DE69829975D1 - Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle - Google Patents

Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Info

Publication number
DE69829975D1
DE69829975D1 DE69829975T DE69829975T DE69829975D1 DE 69829975 D1 DE69829975 D1 DE 69829975D1 DE 69829975 T DE69829975 T DE 69829975T DE 69829975 T DE69829975 T DE 69829975T DE 69829975 D1 DE69829975 D1 DE 69829975D1
Authority
DE
Germany
Prior art keywords
microparticles
taxed
molecules
synthetic
natural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69829975T
Other languages
English (en)
Other versions
DE69829975T2 (de
Inventor
Jenny Cowdall
John Davies
Mark Roberts
Anders Carlsson
Roberto Solaro
Giuseppe Mazzanti
Elisabetta Chiellini
Federica Chiellini
Erik Soederlind
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISI IST SIEROVACCINOGENO ITAL
Original Assignee
ISI IST SIEROVACCINOGENO ITAL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISI IST SIEROVACCINOGENO ITAL filed Critical ISI IST SIEROVACCINOGENO ITAL
Application granted granted Critical
Publication of DE69829975D1 publication Critical patent/DE69829975D1/de
Publication of DE69829975T2 publication Critical patent/DE69829975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69829975T 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle Expired - Lifetime DE69829975T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97RM000418A IT1293088B1 (it) 1997-07-10 1997-07-10 Microparticelle per il rilascio controllato di molecole biologicamente attive e loro uso in terapia, profilassi e diagnostica in vitro e in
ITRM970418 1997-07-10
PCT/IT1998/000192 WO1999002135A1 (en) 1997-07-10 1998-07-09 Microparticles for controlled delivery of biologically active molecules

Publications (2)

Publication Number Publication Date
DE69829975D1 true DE69829975D1 (de) 2005-06-02
DE69829975T2 DE69829975T2 (de) 2006-03-09

Family

ID=11405168

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829975T Expired - Lifetime DE69829975T2 (de) 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Country Status (7)

Country Link
EP (1) EP1003482B1 (de)
AT (1) ATE293958T1 (de)
AU (1) AU8240998A (de)
DE (1) DE69829975T2 (de)
ES (1) ES2242287T3 (de)
IT (1) IT1293088B1 (de)
WO (1) WO1999002135A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1407787T3 (da) 2001-06-20 2009-06-02 Dainippon Sumitomo Pharma Co Fremgangsmåde til fremme af nukleinsyreoverförsel
JP2008067717A (ja) * 2001-06-20 2008-03-27 Dainippon Sumitomo Pharma Co Ltd 核酸導入を促進させる方法
US7166575B2 (en) 2002-12-17 2007-01-23 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
US7186692B2 (en) 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
JP2006516262A (ja) 2002-12-17 2006-06-29 ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド Ｙ２受容体結合ペプチドの粘膜送達促進のための組成物および方法ならびに肥満症の治療法および予防法
US7229966B2 (en) 2002-12-17 2007-06-12 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity
US10953103B2 (en) 2015-11-06 2021-03-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V Composition comprising a biocompatible and biodegradable polymer, nanocarriers and a drug and methods of making and using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2660556B1 (fr) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Microspheres, leur procede de preparation et leur utilisation.
IT1244511B (it) * 1991-04-15 1994-07-15 Isi Ist Sierovaccinogeno Ital Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione.
EP0644771B2 (de) * 1992-06-11 2006-12-06 Alkermes Controlled Therapeutics, Inc. Enythropoietin enthaltendes arzneimittelabgabesystem
CA2160878A1 (en) * 1993-04-19 1994-10-27 Sandra Gertrude Mcelligott Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression

Also Published As

Publication number Publication date
EP1003482A1 (de) 2000-05-31
DE69829975T2 (de) 2006-03-09
IT1293088B1 (it) 1999-02-11
AU8240998A (en) 1999-02-08
WO1999002135A1 (en) 1999-01-21
ES2242287T3 (es) 2005-11-01
ITRM970418A1 (it) 1999-01-10
EP1003482B1 (de) 2005-04-27
ITRM970418A0 (de) 1997-07-10
ATE293958T1 (de) 2005-05-15

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Legal Events

Date Code Title Description
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