ATE293958T1 - Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle - Google Patents

Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Info

Publication number
ATE293958T1
ATE293958T1 AT98932506T AT98932506T ATE293958T1 AT E293958 T1 ATE293958 T1 AT E293958T1 AT 98932506 T AT98932506 T AT 98932506T AT 98932506 T AT98932506 T AT 98932506T AT E293958 T1 ATE293958 T1 AT E293958T1
Authority
AT
Austria
Prior art keywords
microparticles
biologically active
controlled delivery
active molecules
synthetic
Prior art date
Application number
AT98932506T
Other languages
English (en)
Inventor
Jenny Cowdall
John Davies
Mark Roberts
Anders Carlsson
Roberto Solaro
Giuseppe Mazzanti
Elisabetta Chiellini
Federica Chiellini
Erik Soederlind
Original Assignee
Isi Ist Sierovaccinogeno Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isi Ist Sierovaccinogeno Ital filed Critical Isi Ist Sierovaccinogeno Ital
Application granted granted Critical
Publication of ATE293958T1 publication Critical patent/ATE293958T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT98932506T 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle ATE293958T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97RM000418A IT1293088B1 (it) 1997-07-10 1997-07-10 Microparticelle per il rilascio controllato di molecole biologicamente attive e loro uso in terapia, profilassi e diagnostica in vitro e in
PCT/IT1998/000192 WO1999002135A1 (en) 1997-07-10 1998-07-09 Microparticles for controlled delivery of biologically active molecules

Publications (1)

Publication Number Publication Date
ATE293958T1 true ATE293958T1 (de) 2005-05-15

Family

ID=11405168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98932506T ATE293958T1 (de) 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Country Status (7)

Country Link
EP (1) EP1003482B1 (de)
AT (1) ATE293958T1 (de)
AU (1) AU8240998A (de)
DE (1) DE69829975T2 (de)
ES (1) ES2242287T3 (de)
IT (1) IT1293088B1 (de)
WO (1) WO1999002135A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1407787B1 (de) 2001-06-20 2009-04-29 Dainippon Sumitomo Pharma Co., Ltd. Verfahren zur förderung des nukleinsäuretransfers
JP2008067717A (ja) * 2001-06-20 2008-03-27 Dainippon Sumitomo Pharma Co Ltd 核酸導入を促進させる方法
US7166575B2 (en) 2002-12-17 2007-01-23 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
US7229966B2 (en) 2002-12-17 2007-06-12 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity
EP1581245A2 (de) 2002-12-17 2005-10-05 Nastech Pharmaceutical Company Inc. Zusammensetzungen und verfahren für verstärkte mukosale abgabe von y2-rezeptorbindenden peptiden sowie verfahren zur behandlung und prävention von adipositas
US7186692B2 (en) 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
EP3370694A1 (de) 2015-11-06 2018-09-12 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit einem biokompatiblen und biologisch abbaubaren polymer, nanoträger und arzneimittel sowie verfahren zur herstellung und verwendung davon

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2660556B1 (fr) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Microspheres, leur procede de preparation et leur utilisation.
IT1244511B (it) * 1991-04-15 1994-07-15 Isi Ist Sierovaccinogeno Ital Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione.
ATE222500T1 (de) * 1992-06-11 2002-09-15 Alkermes Inc Enythropoietin enthaltendes arzneimittelabgabesystem
AU6707194A (en) * 1993-04-19 1994-11-08 Medisorb Technologies International L.P. Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression

Also Published As

Publication number Publication date
ES2242287T3 (es) 2005-11-01
EP1003482A1 (de) 2000-05-31
WO1999002135A1 (en) 1999-01-21
ITRM970418A0 (de) 1997-07-10
DE69829975D1 (de) 2005-06-02
EP1003482B1 (de) 2005-04-27
DE69829975T2 (de) 2006-03-09
AU8240998A (en) 1999-02-08
ITRM970418A1 (it) 1999-01-10
IT1293088B1 (it) 1999-02-11

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Legal Events

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