ES2176459T3 - Patrones y soluciones de contraste estabilizados. - Google Patents
Patrones y soluciones de contraste estabilizados.Info
- Publication number
- ES2176459T3 ES2176459T3 ES96916602T ES96916602T ES2176459T3 ES 2176459 T3 ES2176459 T3 ES 2176459T3 ES 96916602 T ES96916602 T ES 96916602T ES 96916602 T ES96916602 T ES 96916602T ES 2176459 T3 ES2176459 T3 ES 2176459T3
- Authority
- ES
- Spain
- Prior art keywords
- solutions
- contrast patterns
- stabilized contrast
- rapamycin
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/102499—Blood gas standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/106664—Blood serum or blood plasma standard or control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Polymerisation Methods In General (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION ACUOSA IN VITRO QUE CONTIENE UN FARMACO, PREFERENTEMENTE TACROLIMUS O RAPAMICINA, QUE TIENE UNA ESTABILIDAD MEJORADA. EN LA INVENCION SE HACE USO DE UNA PROTEINA AGLUTINANTE, PREFERENTEMENTE LA FKBP, PARA ESTABILIZAR EL FARMACO EN UNA MATRIZ ACUOSA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/474,589 US5635406A (en) | 1995-06-07 | 1995-06-07 | Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2176459T3 true ES2176459T3 (es) | 2002-12-01 |
Family
ID=23884190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96916602T Expired - Lifetime ES2176459T3 (es) | 1995-06-07 | 1996-05-24 | Patrones y soluciones de contraste estabilizados. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5635406A (es) |
EP (1) | EP0832433B1 (es) |
JP (1) | JP3863564B2 (es) |
AT (1) | ATE214803T1 (es) |
CA (1) | CA2219931C (es) |
DE (1) | DE69619982T2 (es) |
ES (1) | ES2176459T3 (es) |
WO (1) | WO1996041184A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6709873B1 (en) * | 1997-04-09 | 2004-03-23 | Isodiagnostika Inc. | Method for production of antibodies to specific sites of rapamycin |
US7078495B1 (en) * | 1999-08-03 | 2006-07-18 | Dade Behring Inc. | Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus |
US6613083B2 (en) * | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
US20030054042A1 (en) * | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
US7186518B2 (en) * | 2003-11-21 | 2007-03-06 | Dade Behring Inc. | Method and composition useful for determining FK 506 |
US8022188B2 (en) * | 2006-04-24 | 2011-09-20 | Abbott Laboratories | Immunosuppressant binding antibodies and methods of obtaining and using same |
US7642338B2 (en) * | 2006-06-20 | 2010-01-05 | Siemens Healthcare Diagnostics Inc. | Tacrolimus standard and methods of using same |
US8329424B2 (en) | 2010-06-25 | 2012-12-11 | Siemens Healthcare Diagnostics | Reduction in false results in assay measurements |
US8809003B2 (en) | 2010-06-25 | 2014-08-19 | Siemens Healthcare Diagnostics Inc. | Reduction in false results in assay measurements |
US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
ES2576927T3 (es) | 2010-10-22 | 2016-07-12 | T2 Biosystems, Inc. | Sistemas de RMN y métodos para la detección rápida de analitos |
WO2013158281A1 (en) | 2012-04-20 | 2013-10-24 | T2 Biosystems, Inc. | Compositions and methods for detection of candida species |
GB201309376D0 (en) * | 2013-05-24 | 2013-07-10 | Chronos Therapeutics Ltd | Medical methods and compounds for medical use |
WO2017127731A1 (en) | 2016-01-21 | 2017-07-27 | T2 Biosystems, Inc. | Nmr methods and systems for the rapid detection of bacteria |
CN110849694B (zh) * | 2019-12-02 | 2022-03-18 | 北京丹大生物技术有限公司 | 一种他克莫司全血样本前处理液及其使用方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3886265T2 (de) * | 1987-06-05 | 1994-04-28 | Fujisawa Pharmaceutical Co | Anti-FR-900506-Stoffe-Antikörper und höchstempfindliches Enzym-Immunoassay-Verfahren. |
US5322772A (en) * | 1991-04-09 | 1994-06-21 | Children's Research Institute | Rapamycin assay |
WO1994024568A1 (en) * | 1993-04-20 | 1994-10-27 | Abbott Laboratories | Stable aqueous fk506 standards |
AU4400593A (en) * | 1992-06-05 | 1994-01-04 | Abbott Laboratories | Methods and reagents for the determination of immunosuppressive agents |
GB9307491D0 (en) * | 1993-04-08 | 1993-06-02 | Sandoz Ltd | Organic compounds |
GB9313163D0 (en) * | 1993-06-25 | 1993-08-11 | Health Lab Service Board | Storage of antibodies |
-
1995
- 1995-06-07 US US08/474,589 patent/US5635406A/en not_active Expired - Lifetime
-
1996
- 1996-05-24 DE DE69619982T patent/DE69619982T2/de not_active Expired - Lifetime
- 1996-05-24 JP JP50070597A patent/JP3863564B2/ja not_active Expired - Lifetime
- 1996-05-24 ES ES96916602T patent/ES2176459T3/es not_active Expired - Lifetime
- 1996-05-24 EP EP96916602A patent/EP0832433B1/en not_active Expired - Lifetime
- 1996-05-24 CA CA2219931A patent/CA2219931C/en not_active Expired - Lifetime
- 1996-05-24 AT AT96916602T patent/ATE214803T1/de not_active IP Right Cessation
- 1996-05-24 WO PCT/US1996/007617 patent/WO1996041184A1/en active IP Right Grant
- 1996-09-27 US US08/723,203 patent/US5736401A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69619982T2 (de) | 2002-11-21 |
WO1996041184A1 (en) | 1996-12-19 |
ATE214803T1 (de) | 2002-04-15 |
JP2001515581A (ja) | 2001-09-18 |
JP3863564B2 (ja) | 2006-12-27 |
US5736401A (en) | 1998-04-07 |
EP0832433B1 (en) | 2002-03-20 |
CA2219931A1 (en) | 1996-12-19 |
EP0832433A1 (en) | 1998-04-01 |
DE69619982D1 (de) | 2002-04-25 |
CA2219931C (en) | 2012-05-15 |
US5635406A (en) | 1997-06-03 |
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