DE69832166D1 - Matrix zur trennung und nutzung der matrix zur trennung - Google Patents

Matrix zur trennung und nutzung der matrix zur trennung

Info

Publication number
DE69832166D1
DE69832166D1 DE69832166T DE69832166T DE69832166D1 DE 69832166 D1 DE69832166 D1 DE 69832166D1 DE 69832166 T DE69832166 T DE 69832166T DE 69832166 T DE69832166 T DE 69832166T DE 69832166 D1 DE69832166 D1 DE 69832166D1
Authority
DE
Germany
Prior art keywords
matrix
separation
micropores
penetrate
openings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69832166T
Other languages
English (en)
Other versions
DE69832166T2 (de
Inventor
Jan Bergstroem
Rolf Berglund
Lennart Soederberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Sweden AB
Original Assignee
Amersham Bioscience AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20406014&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69832166(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amersham Bioscience AB filed Critical Amersham Bioscience AB
Publication of DE69832166D1 publication Critical patent/DE69832166D1/de
Application granted granted Critical
Publication of DE69832166T2 publication Critical patent/DE69832166T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • B01J20/3212Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/285Porous sorbents based on polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • G01N2030/524Physical parameters structural properties
    • G01N2030/528Monolithic sorbent material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
DE69832166T 1997-03-04 1998-03-04 Matrix zur trennung und nutzung der matrix zur trennung Revoked DE69832166T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9700769A SE9700769D0 (sv) 1997-03-04 1997-03-04 Matriser för separation och separation som utnyttjar matriserna
SE9700769 1997-03-04
PCT/SE1998/000387 WO1998039094A1 (en) 1997-03-04 1998-03-04 Matrices for separation and separation exploiting said matrices

Publications (2)

Publication Number Publication Date
DE69832166D1 true DE69832166D1 (de) 2005-12-08
DE69832166T2 DE69832166T2 (de) 2006-08-03

Family

ID=20406014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832166T Revoked DE69832166T2 (de) 1997-03-04 1998-03-04 Matrix zur trennung und nutzung der matrix zur trennung

Country Status (10)

Country Link
US (1) US6572766B1 (de)
EP (1) EP0980288B1 (de)
JP (1) JP4135812B2 (de)
AT (1) ATE308380T1 (de)
AU (1) AU729313B2 (de)
CA (1) CA2281846C (de)
DE (1) DE69832166T2 (de)
ES (1) ES2251766T3 (de)
SE (1) SE9700769D0 (de)
WO (1) WO1998039094A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9601368D0 (sv) * 1996-04-11 1996-04-11 Pharmacia Biotech Ab Process for the production of a porous cross-linked polysaccharide gel
SE9904272D0 (sv) * 1999-11-25 1999-11-25 Amersham Pharm Biotech Ab A method for selective removal of a substance from samples containing compounds having nucleic acid structure
JP2005512070A (ja) * 2001-11-27 2005-04-28 シファーゲン バイオシステムズ, インコーポレイテッド ヒドロキシアパタイトが充填された細孔を有する酸化鉱物ビーズからなる複合クロマトグラフィー吸着媒
US7347976B2 (en) 2001-12-20 2008-03-25 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix
US7192560B2 (en) 2001-12-20 2007-03-20 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
US6749749B2 (en) * 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
US7473367B2 (en) * 2002-06-26 2009-01-06 Dionex Corporation Monolithic column
US20050061745A1 (en) * 2002-06-26 2005-03-24 Teledyne Isco, Inc. Separation system, components of a separation system and methods of making and using them
EP1525052A1 (de) * 2002-07-26 2005-04-27 Applera Corporation Grössendiskriminierende ionenaustauscherteilchen
US20040016702A1 (en) * 2002-07-26 2004-01-29 Applera Corporation Device and method for purification of nucleic acids
SE0202551D0 (sv) * 2002-08-27 2002-08-27 Amersham Biosciences Ab Chromatographic two-layer particles
US7981600B2 (en) * 2003-04-17 2011-07-19 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene
US8137548B2 (en) * 2003-10-17 2012-03-20 Zirchrom Separations, Inc. Chelator-modified inorganic oxide particles
US7939249B2 (en) 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step
US20050181378A1 (en) * 2004-02-18 2005-08-18 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
US20050196856A1 (en) * 2004-02-18 2005-09-08 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
JP2007522807A (ja) * 2004-02-18 2007-08-16 アプレラ コーポレイション 高分子電解質コーティングされたサイズ排除イオン交換粒子
US20060160122A1 (en) * 2004-02-18 2006-07-20 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
SE0400490D0 (sv) 2004-02-26 2004-02-26 Amersham Biosciences Ab Plasmid purification
SE0502485L (sv) * 2005-11-09 2007-05-10 Peter Viberg Partiklar
WO2007063701A1 (ja) * 2005-12-02 2007-06-07 Sekisui Chemical Co., Ltd. 親水性高分子微粒子、イオン交換液体クロマトグラフィー用充填剤及びイオン交換液体クロマトグラフィー用充填剤の製造方法
WO2009014481A1 (en) * 2007-07-25 2009-01-29 Ge Healthcare Bio-Sciences Ab Separation matrix
CN102015094B (zh) * 2008-04-22 2016-11-09 通用电气医疗集团生物工艺研发股份公司 层析介质
WO2010027696A1 (en) * 2008-08-25 2010-03-11 Ge Healthcare Bio-Sciences Corp. Simple load and elute process for purification of genomic dna
EP2470642A4 (de) * 2009-08-27 2013-03-20 Ge Healthcare Bio Sciences Ab Zellexpansionsverfahren
WO2011035282A1 (en) * 2009-09-21 2011-03-24 Ge Healthcare Bio-Sciences Ab Dual capture separation
CN102821843A (zh) * 2010-02-19 2012-12-12 通用电气健康护理生物科学股份公司 色谱介质的制备方法
AU2011245735A1 (en) * 2010-04-26 2012-11-15 Ge Healthcare Bio-Sciences Ab Method for production of chromatography media
JP5474881B2 (ja) * 2010-07-28 2014-04-16 ローム アンド ハース カンパニー 向上したクロマトグラフィー媒体の製造方法および使用方法
JP5631271B2 (ja) * 2010-07-28 2014-11-26 ローム アンド ハース カンパニーRohm And Haas Company 改良されたクロマトグラフィー媒体の製造方法および使用方法
WO2014092636A1 (en) * 2012-12-14 2014-06-19 Ge Healthcare Bio-Sciences Ab Method for cleaning of packed bed chromatography columns
CA2910119A1 (en) 2013-05-20 2014-11-27 Shantha Biotechnics Private Limited Purification of polysaccharide protein conjugates
US9731249B2 (en) * 2014-04-15 2017-08-15 Ut-Battelle, Llc Polymeric molecular sieve membranes for gas separation
WO2016117574A1 (ja) * 2015-01-19 2016-07-28 日立化成株式会社 分離材
JP6746919B2 (ja) * 2016-01-15 2020-08-26 日立化成株式会社 分離材及びカラム

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959251A (en) 1970-06-25 1976-05-25 Exploaterings Aktiebolaget T.B.F. Stabilized agar product and method for its stabilization
LU73094A1 (de) * 1975-07-29 1977-03-24
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
ATE15378T1 (de) * 1980-06-27 1985-09-15 Akzo Nv Mit einer unbeweglichen organischen phase ueberzogenes anorganisches poroeses traegermaterial, anwendung fuer die chromatographie und sein herstellungsverfahren.
SE8205908D0 (sv) * 1982-10-18 1982-10-18 Pharmacia Diagnostics Ab Sett att bilda polymerskikt
SE8302758L (sv) 1983-05-17 1984-11-18 Pharmacia Ab Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening
SE470261B (sv) 1984-05-17 1993-12-20 Jerker Porath Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering
SE470099B (sv) 1984-05-17 1993-11-08 Jerker Porath Sulfonaktiverade tioeteradsorbenter för separation av t ex protein
US4544485A (en) 1984-08-31 1985-10-01 Purdue Research Foundation Chromatographic method and means
US4794002A (en) * 1985-11-01 1988-12-27 Monsanto Company Modified polymeric surfaces and process for preparing same
US4746572A (en) * 1986-11-28 1988-05-24 E. I. Dupont De Nemours And Company Structures surface modified with bidentate silanes
US4871711A (en) * 1986-12-29 1989-10-03 Aluminum Company Of America Active material produced from metal oxide/hydroxide particles and phosphate esters
ATE179901T1 (de) 1989-07-06 1999-05-15 Perseptive Biosystems Inc Chromatographieverfahren
US5030352A (en) * 1990-01-25 1991-07-09 Purdue Research Foundation Coated media for chromatography
DK164303C (da) 1990-05-14 1992-10-19 Vik Consult Isolering til et roer eller en kanal med en relativ lav overfladetemperatur og fremgangsmaade til fremstilling af isoleringen
DK165090D0 (da) 1990-07-09 1990-07-09 Kem En Tec As Konglomererede partikler
US5128291A (en) * 1990-12-11 1992-07-07 Wax Michael J Porous titania or zirconia spheres
SE9101149D0 (sv) 1991-04-17 1991-04-17 Pharmacia Lkb Biotech Beads for down stream processing
US5306561A (en) 1992-02-20 1994-04-26 Cornell Research Foundation, Inc. Preparation of surface-functional polymer particles
SE9200827D0 (sv) 1992-03-18 1992-03-18 Pharmacia Lkb Biotech Supet porous polysaccharide gels
US5906734A (en) * 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
JPH08502534A (ja) * 1992-10-21 1996-03-19 コーネル リサーチ ファウンデーション、インコーポレーテッド 多孔物質の細孔サイズ選択的修飾法
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
US5653875A (en) * 1994-02-04 1997-08-05 Supelco, Inc. Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices
SE9401960L (sv) 1994-06-07 1995-12-08 Sven Oscarsson Alkalibeständigt proteinadsorbent
US5522994A (en) 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
SE9600590D0 (sv) 1996-02-19 1996-02-19 Pharmacia Biotech Ab Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
SE9700768D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Förfarande för att introducera funktionalitet

Also Published As

Publication number Publication date
CA2281846C (en) 2007-07-03
EP0980288B1 (de) 2005-11-02
AU729313B2 (en) 2001-02-01
SE9700769D0 (sv) 1997-03-04
WO1998039094A1 (en) 1998-09-11
JP2001514745A (ja) 2001-09-11
ATE308380T1 (de) 2005-11-15
CA2281846A1 (en) 1998-09-11
US6572766B1 (en) 2003-06-03
ES2251766T3 (es) 2006-05-01
AU6644298A (en) 1998-09-22
EP0980288A1 (de) 2000-02-23
JP4135812B2 (ja) 2008-08-20
DE69832166T2 (de) 2006-08-03

Similar Documents

Publication Publication Date Title
DE69832166D1 (de) Matrix zur trennung und nutzung der matrix zur trennung
DE59702949D1 (de) Verfahren und Vorrichtung zur Herstellung von Homo- und Copolymeren in Emulsionspolymerisationstechnik
DE69840251D1 (de) Festpolymerelektrolyt und Verfahren zur Herstellung
DE69835923D1 (de) Verfahren und vorrichtung zur herstellung von kornorientiertem stahlblech mit hervorragenden magnetischen eigenschaften
DE69728846T2 (de) Verfahren zur Herstellung von Gummi-modifizierte feste Silikon-Harze und daraus hergestellte Komposite
DE69702677D1 (de) Keramikmatrix-Verbundwerkstoff und Verfahren zur Herstellung desselben
DE59102505D1 (de) Vorrichtung zur Rekombination von Wasserstoff und Sauerstoff.
DE69007405D1 (de) Gasentfeuchter und Verfahren zur Gasentfeuchtung.
DE69722171D1 (de) Vorrichtung zur markierung von gewebe
DE60109726D1 (de) Luftverwaltungssystem zur Herstellung von Vliesstoffen und Verbundvliesstoffen
DE69716224D1 (de) Vorrichtungen zur Herstellung von Feinpartikeln
DE69708515D1 (de) Verbesserte Photoresiste und Verfahren zur Herstellung von Druckplatten
DE69605995D1 (de) Sicherungsplatte und Verfahren zur Herstellung der Sicherungsplatte
ID21403A (id) Polimer baru dan penggunaanya
FI945118A (fi) Polymeerisysteemejä, menetelmä niiden valmistamiseksi sekä niiden käyttö painovärien valmistukseen
DE69723589D1 (de) Osmotisches verabreichungssystem und methode zur leistungserhöhung und verbesserung der initialwirkung von osmotischen verabreichungssystemen
DE3888520D1 (de) Hoch vernetzte Polymerteilchen und Verfahren zur Herstellung derselben.
DE69825310D1 (de) Verfahren und vorrichtung zur herstellung von polymeren
DE69605835D1 (de) Sicherungsplatte und Verfahren zur Herstellung der Sicherungsplatte
DE59705368D1 (de) Vorrichtung zur Herstellung von Kunststoff-Verbund-Rohren
ID17415A (id) Campuran monomer aromatik viniliden dan alpa-olefin serta antar-polimer monomer viniliden sikloalipatik atau alipatik
DE69813612D1 (de) Automatisches system zur erstellung und verwaltung von strafzetteln
DE69723915D1 (de) Vorrichtung zur automatischen Herstellung von Druckringen mit formschlüssigem Verschluss
DE69718858D1 (de) Vorrichtung zur Druckregelung und Radaufhängung
DE69728113D1 (de) Negativer widerstand des molekulardispersionstyps und verfahren zur herstellung

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: GE HEALTHCARE BIO-SCIENCES AB, UPPSALA, SE

8363 Opposition against the patent
8331 Complete revocation