ATE291023T1 - Herstellung von oxymorphon, oxycodon und derivaten davon - Google Patents

Herstellung von oxymorphon, oxycodon und derivaten davon

Info

Publication number
ATE291023T1
ATE291023T1 AT98934213T AT98934213T ATE291023T1 AT E291023 T1 ATE291023 T1 AT E291023T1 AT 98934213 T AT98934213 T AT 98934213T AT 98934213 T AT98934213 T AT 98934213T AT E291023 T1 ATE291023 T1 AT E291023T1
Authority
AT
Austria
Prior art keywords
synthesis
oxymorphone
oxycodone
derivatives
production
Prior art date
Application number
AT98934213T
Other languages
German (de)
English (en)
Inventor
Bao-Shan Huang
Aris Christodoulou
Yansong Lu
Ben-Yi Ji
Original Assignee
Penick Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25401603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE291023(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corp filed Critical Penick Corp
Application granted granted Critical
Publication of ATE291023T1 publication Critical patent/ATE291023T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT98934213T 1997-07-11 1998-07-10 Herstellung von oxymorphon, oxycodon und derivaten davon ATE291023T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/893,464 US5869669A (en) 1996-07-26 1997-07-11 Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
PCT/US1998/013592 WO1999002529A1 (en) 1997-07-11 1998-07-10 Preparation of oxymorphone, oxycodone and derivatives

Publications (1)

Publication Number Publication Date
ATE291023T1 true ATE291023T1 (de) 2005-04-15

Family

ID=25401603

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98934213T ATE291023T1 (de) 1997-07-11 1998-07-10 Herstellung von oxymorphon, oxycodon und derivaten davon

Country Status (19)

Country Link
US (7) US5869669A (https=)
EP (1) EP1000065B1 (https=)
JP (1) JP2001518444A (https=)
KR (1) KR100363486B1 (https=)
CN (1) CN1152880C (https=)
AT (1) ATE291023T1 (https=)
AU (1) AU740822B2 (https=)
CA (1) CA2296035C (https=)
DE (1) DE69829379D1 (https=)
HU (1) HUP0003918A3 (https=)
IL (1) IL133792A0 (https=)
IN (1) IN1998KO01500A (https=)
NO (1) NO20000111L (https=)
RU (1) RU2183636C2 (https=)
SK (1) SK102000A3 (https=)
TR (1) TR200000033T2 (https=)
TW (1) TW505648B (https=)
WO (1) WO1999002529A1 (https=)
ZA (1) ZA986144B (https=)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
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RU2215741C1 (ru) * 2002-11-05 2003-11-10 Открытое Акционерное Общество "Международная Научно-Технологическая Корпорация" Сложные эфиры n-замещенных 14-гидроксиморфинанов и способ их получения
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CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
EP3997092A4 (en) 2019-07-08 2023-09-06 University of Health Sciences & Pharmacy in St. Louis G-PROTEIN INFLUENCED OPIOID RECEPTOR AGONIST/ANALGESICS WITH REDUCED ARRESTIN RECRUITMENT
JP2023515918A (ja) 2020-01-13 2023-04-17 デュレクト コーポレーション 不純物が低減された徐放性薬物送達システム及び関連の方法
CN114621239B (zh) * 2020-12-10 2026-02-03 鲁南制药集团股份有限公司 一种纳曲酮的制备方法
KR20230127222A9 (ko) * 2020-12-28 2024-03-25 나빈 삭세나 리서치 앤드 테크놀로지 피브이티. 엘티디. 모르핀으로부터 노르옥시모르폰의 합성을 위한 신규의 제조방법
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

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Also Published As

Publication number Publication date
EP1000065B1 (en) 2005-03-16
KR20010021693A (ko) 2001-03-15
US5952495A (en) 1999-09-14
DE69829379D1 (de) 2005-04-21
NO20000111L (no) 2000-02-25
US5869669A (en) 1999-02-09
TR200000033T2 (tr) 2000-12-21
US5922876A (en) 1999-07-13
AU740822B2 (en) 2001-11-15
AU8379198A (en) 1999-02-08
EP1000065A4 (en) 2001-09-12
HUP0003918A3 (en) 2003-04-28
SK102000A3 (en) 2000-07-11
IL133792A0 (en) 2001-04-30
EP1000065A1 (en) 2000-05-17
RU2183636C2 (ru) 2002-06-20
CA2296035A1 (en) 1999-01-21
US6008355A (en) 1999-12-28
CA2296035C (en) 2004-04-13
US6008354A (en) 1999-12-28
WO1999002529A1 (en) 1999-01-21
HK1028025A1 (en) 2001-02-02
TW505648B (en) 2002-10-11
CN1152880C (zh) 2004-06-09
ZA986144B (en) 1999-05-19
NO20000111D0 (no) 2000-01-10
US6013796A (en) 2000-01-11
IN1998KO01500A (https=) 2005-03-11
CN1272845A (zh) 2000-11-08
US5948788A (en) 1999-09-07
KR100363486B1 (ko) 2002-12-16
HUP0003918A2 (hu) 2001-07-30
JP2001518444A (ja) 2001-10-16

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