ATE289815T1 - Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie - Google Patents

Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie

Info

Publication number
ATE289815T1
ATE289815T1 AT96945220T AT96945220T ATE289815T1 AT E289815 T1 ATE289815 T1 AT E289815T1 AT 96945220 T AT96945220 T AT 96945220T AT 96945220 T AT96945220 T AT 96945220T AT E289815 T1 ATE289815 T1 AT E289815T1
Authority
AT
Austria
Prior art keywords
glaucoma
medication
preparing
treatment
sulfonyl compounds
Prior art date
Application number
AT96945220T
Other languages
English (en)
Inventor
Michael A Kapin
Louis M Desantis Jr
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE289815T1 publication Critical patent/ATE289815T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
AT96945220T 1995-12-21 1996-12-20 Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie ATE289815T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US935195P 1995-12-21 1995-12-21
PCT/US1996/020197 WO1997023222A1 (en) 1995-12-21 1996-12-20 Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia

Publications (1)

Publication Number Publication Date
ATE289815T1 true ATE289815T1 (de) 2005-03-15

Family

ID=21737108

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96945220T ATE289815T1 (de) 1995-12-21 1996-12-20 Verwendung von substituierten isochinolinsulfonyl-verbindungen zur herstellung eines medikaments für die behandlung von glaukom und okularer ischämie

Country Status (14)

Country Link
US (2) US6271224B1 (de)
EP (1) EP0868186B1 (de)
JP (1) JP3719609B2 (de)
KR (1) KR100452715B1 (de)
CN (1) CN1155383C (de)
AT (1) ATE289815T1 (de)
AU (1) AU720326B2 (de)
DE (1) DE69634414T2 (de)
ES (1) ES2238702T3 (de)
HK (1) HK1015691A1 (de)
MX (1) MX9805033A (de)
PT (1) PT868186E (de)
TW (1) TW534814B (de)
WO (1) WO1997023222A1 (de)

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Also Published As

Publication number Publication date
DE69634414D1 (de) 2005-04-07
JP3719609B2 (ja) 2005-11-24
TW534814B (en) 2003-06-01
HK1015691A1 (en) 1999-10-22
MX9805033A (es) 1998-09-30
ES2238702T3 (es) 2005-09-01
AU720326B2 (en) 2000-05-25
WO1997023222A1 (en) 1997-07-03
CN1155383C (zh) 2004-06-30
US6271224B1 (en) 2001-08-07
CN1207680A (zh) 1999-02-10
JP2001509780A (ja) 2001-07-24
PT868186E (pt) 2005-05-31
KR19990076580A (ko) 1999-10-15
KR100452715B1 (ko) 2004-12-17
US6403590B1 (en) 2002-06-11
DE69634414T2 (de) 2005-11-17
EP0868186B1 (de) 2005-03-02
EP0868186A1 (de) 1998-10-07
AU1464497A (en) 1997-07-17

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