ATE286980T1 - Die p110-delta katalytische untereinheit der phosphatidylinositol-3-kinase - Google Patents

Die p110-delta katalytische untereinheit der phosphatidylinositol-3-kinase

Info

Publication number
ATE286980T1
ATE286980T1 AT97948540T AT97948540T ATE286980T1 AT E286980 T1 ATE286980 T1 AT E286980T1 AT 97948540 T AT97948540 T AT 97948540T AT 97948540 T AT97948540 T AT 97948540T AT E286980 T1 ATE286980 T1 AT E286980T1
Authority
AT
Austria
Prior art keywords
delta
catalytic subunit
phosphatidylinositol
kinase
delta catalytic
Prior art date
Application number
AT97948540T
Other languages
English (en)
Inventor
David H Chantry
Merl F Hoekstra
Douglas A Holtzman
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE286980T1 publication Critical patent/ATE286980T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Record Carriers (AREA)
  • Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97948540T 1996-11-25 1997-11-25 Die p110-delta katalytische untereinheit der phosphatidylinositol-3-kinase ATE286980T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/777,405 US5858753A (en) 1996-11-25 1996-11-25 Lipid kinase
PCT/US1997/021655 WO1998023760A1 (en) 1996-11-25 1997-11-25 Phosphatidylinositol 3-kinase p110 delta catalytic subunit

Publications (1)

Publication Number Publication Date
ATE286980T1 true ATE286980T1 (de) 2005-01-15

Family

ID=25110168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97948540T ATE286980T1 (de) 1996-11-25 1997-11-25 Die p110-delta katalytische untereinheit der phosphatidylinositol-3-kinase

Country Status (11)

Country Link
US (3) US5858753A (de)
EP (2) EP1522584A3 (de)
JP (1) JP2000505653A (de)
AT (1) ATE286980T1 (de)
AU (1) AU5458798A (de)
CA (1) CA2243944A1 (de)
DE (1) DE69732228T2 (de)
DK (1) DK0891428T3 (de)
ES (1) ES2236834T3 (de)
PT (1) PT891428E (de)
WO (1) WO1998023760A1 (de)

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Also Published As

Publication number Publication date
EP0891428B1 (de) 2005-01-12
EP0891428A1 (de) 1999-01-20
ES2236834T3 (es) 2005-07-16
WO1998023760A1 (en) 1998-06-04
DE69732228T2 (de) 2005-12-29
EP1522584A3 (de) 2005-06-15
US5882910A (en) 1999-03-16
US5858753A (en) 1999-01-12
AU5458798A (en) 1998-06-22
PT891428E (pt) 2005-05-31
CA2243944A1 (en) 1998-06-04
DK0891428T3 (da) 2005-05-30
US5985589A (en) 1999-11-16
JP2000505653A (ja) 2000-05-16
EP1522584A2 (de) 2005-04-13
DE69732228D1 (de) 2005-02-17

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