ATE283365T1 - Il-1 rezeptor fusionsproteine verwendet als antagoniste und verfahren zu deren verwendung und herstellung - Google Patents

Il-1 rezeptor fusionsproteine verwendet als antagoniste und verfahren zu deren verwendung und herstellung

Info

Publication number
ATE283365T1
ATE283365T1 AT02007831T AT02007831T ATE283365T1 AT E283365 T1 ATE283365 T1 AT E283365T1 AT 02007831 T AT02007831 T AT 02007831T AT 02007831 T AT02007831 T AT 02007831T AT E283365 T1 ATE283365 T1 AT E283365T1
Authority
AT
Austria
Prior art keywords
antagonists
production
fusion proteins
proteins used
receptor fusion
Prior art date
Application number
AT02007831T
Other languages
English (en)
Inventor
George D Yancopoulos
Neil Stahl
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Application granted granted Critical
Publication of ATE283365T1 publication Critical patent/ATE283365T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02007831T 1998-09-25 1999-09-22 Il-1 rezeptor fusionsproteine verwendet als antagoniste und verfahren zu deren verwendung und herstellung ATE283365T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10185898P 1998-09-25 1998-09-25
US09/313,942 US6472179B2 (en) 1998-09-25 1999-05-19 Receptor based antagonists and methods of making and using

Publications (1)

Publication Number Publication Date
ATE283365T1 true ATE283365T1 (de) 2004-12-15

Family

ID=26798712

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99952942T ATE336583T1 (de) 1998-09-25 1999-09-22 Antagonisten auf rezeptorgrundlage und verfahren zur deren herstellung und verwendung
AT02007831T ATE283365T1 (de) 1998-09-25 1999-09-22 Il-1 rezeptor fusionsproteine verwendet als antagoniste und verfahren zu deren verwendung und herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT99952942T ATE336583T1 (de) 1998-09-25 1999-09-22 Antagonisten auf rezeptorgrundlage und verfahren zur deren herstellung und verwendung

Country Status (19)

Country Link
US (2) US6472179B2 (de)
EP (3) EP1229047B1 (de)
JP (1) JP3902728B2 (de)
CN (1) CN100345970C (de)
AT (2) ATE336583T1 (de)
AU (1) AU758970C (de)
BE (1) BE2010C021I2 (de)
CA (1) CA2345109C (de)
DE (3) DE69922269T2 (de)
DK (1) DK1229047T3 (de)
ES (2) ES2233733T3 (de)
FR (1) FR10C0025I2 (de)
HK (1) HK1045847B (de)
IL (2) IL142103A0 (de)
NO (2) NO329976B1 (de)
NZ (1) NZ510720A (de)
PL (1) PL201246B1 (de)
PT (1) PT1229047E (de)
WO (1) WO2000018932A2 (de)

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Also Published As

Publication number Publication date
US6472179B2 (en) 2002-10-29
NO20011513L (no) 2001-05-25
US20020164690A1 (en) 2002-11-07
JP2002525119A (ja) 2002-08-13
US20020012962A1 (en) 2002-01-31
CN100345970C (zh) 2007-10-31
ES2267300T3 (es) 2007-03-01
HK1035377A1 (en) 2001-11-23
JP3902728B2 (ja) 2007-04-11
DE69922269T2 (de) 2005-12-01
NO20011513D0 (no) 2001-03-23
IL142103A (en) 2007-07-04
EP1115876B1 (de) 2006-08-16
EP1229047A3 (de) 2002-10-02
FR10C0025I2 (fr) 2011-04-01
PL201246B1 (pl) 2009-03-31
NZ510720A (en) 2003-11-28
DE122010000023I2 (de) 2012-04-26
DE69932832D1 (de) 2006-09-28
NO2011003I2 (de) 2011-04-11
AU6499499A (en) 2000-04-17
NO329976B1 (no) 2011-01-31
CA2345109C (en) 2012-12-18
CN1357049A (zh) 2002-07-03
DE69932832T2 (de) 2007-02-08
WO2000018932A9 (en) 2000-08-31
ES2233733T3 (es) 2005-06-16
EP1229047B1 (de) 2004-11-24
EP1405915A1 (de) 2004-04-07
EP1115876A2 (de) 2001-07-18
DK1229047T3 (da) 2005-02-21
AU758970C (en) 2007-05-03
CA2345109A1 (en) 2000-04-06
PT1229047E (pt) 2005-03-31
WO2000018932A3 (en) 2000-11-02
WO2000018932A2 (en) 2000-04-06
AU758970B2 (en) 2003-04-03
IL142103A0 (en) 2002-03-10
BE2010C021I2 (de) 2018-12-04
FR10C0025I1 (de) 2010-05-21
DE122010000023I1 (de) 2012-04-26
HK1045847A1 (en) 2002-12-13
ATE336583T1 (de) 2006-09-15
EP1229047A2 (de) 2002-08-07
HK1045847B (en) 2005-03-24
PL348529A1 (en) 2002-06-03
NO2011003I1 (no) 2011-05-02
DE69922269D1 (de) 2004-12-30

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