ATE277922T1 - Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten - Google Patents
Verfahren zur herstellung von 10, 11methanodibenzosuberanderivatenInfo
- Publication number
- ATE277922T1 ATE277922T1 AT00935852T AT00935852T ATE277922T1 AT E277922 T1 ATE277922 T1 AT E277922T1 AT 00935852 T AT00935852 T AT 00935852T AT 00935852 T AT00935852 T AT 00935852T AT E277922 T1 ATE277922 T1 AT E277922T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- difluoromethanodibenzosuber
- hydroxypropoxy
- piperazin
- quinoline
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
- 125000004194 piperazin-1-yl group Chemical group [H]N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13728499P | 1999-06-03 | 1999-06-03 | |
| PCT/US2000/011863 WO2000075132A1 (en) | 1999-06-03 | 2000-05-30 | Process for preparing a 10,11-methanodibenzosuberane derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE277922T1 true ATE277922T1 (de) | 2004-10-15 |
Family
ID=22476646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00935852T ATE277922T1 (de) | 1999-06-03 | 2000-05-30 | Verfahren zur herstellung von 10, 11methanodibenzosuberanderivaten |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6570016B1 (enExample) |
| EP (1) | EP1198462B1 (enExample) |
| JP (1) | JP2003501425A (enExample) |
| AT (1) | ATE277922T1 (enExample) |
| AU (1) | AU5125200A (enExample) |
| CA (1) | CA2375283A1 (enExample) |
| DE (1) | DE60014386T2 (enExample) |
| ES (1) | ES2228534T3 (enExample) |
| PE (1) | PE20010291A1 (enExample) |
| WO (1) | WO2000075132A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207392B1 (en) * | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| CA2375283A1 (en) * | 1999-06-03 | 2000-12-14 | Eli Lilly And Company | Process for preparing a 10,11-methanodibenzosuberane derivative |
| PT1387683E (pt) | 2001-04-25 | 2005-06-30 | Lilly Co Eli | Novos sais e formas cristalinas de (2r) -anti-5{3-[4-(10,11-difluorometanodibenzosuber-5-il]-2-hidroxipropoxi}quinolina |
| ATE489482T1 (de) * | 2005-08-19 | 2010-12-15 | Nanosphere Inc | Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69322707T2 (de) * | 1992-07-31 | 1999-08-19 | Bristol-Myers Squibb Company | Diphenyl Oxazole-, Thiazole- und Imidazole-Derivate als Inhibitoren der Wiederaufnahme des Adenosins |
| US5643909A (en) * | 1993-04-19 | 1997-07-01 | Syntex (U.S.A.) Inc. | 10,11-Methanodibenzosuberane derivatives |
| AU6167696A (en) * | 1995-06-07 | 1996-12-30 | Dade Chemistry Systems Inc. | Preparation of immunogens and other conjugates of drugs |
| CA2258556A1 (en) * | 1996-06-17 | 1997-12-24 | Julian Stanley Kroin | Drug resistance and multidrug resistance modulators |
| AU3485797A (en) * | 1996-11-22 | 1998-06-10 | Eli Lilly And Company | Drug resistance and multidrug resistance modulators |
| CA2375283A1 (en) * | 1999-06-03 | 2000-12-14 | Eli Lilly And Company | Process for preparing a 10,11-methanodibenzosuberane derivative |
| TWI267511B (en) * | 1999-06-03 | 2006-12-01 | Lilly Co Eli | Process for preparing 10,11-methanobenzosuberane derivatives |
-
2000
- 2000-05-30 CA CA002375283A patent/CA2375283A1/en not_active Abandoned
- 2000-05-30 AU AU51252/00A patent/AU5125200A/en not_active Abandoned
- 2000-05-30 US US09/979,598 patent/US6570016B1/en not_active Expired - Fee Related
- 2000-05-30 WO PCT/US2000/011863 patent/WO2000075132A1/en not_active Ceased
- 2000-05-30 ES ES00935852T patent/ES2228534T3/es not_active Expired - Lifetime
- 2000-05-30 JP JP2001502415A patent/JP2003501425A/ja active Pending
- 2000-05-30 EP EP00935852A patent/EP1198462B1/en not_active Expired - Lifetime
- 2000-05-30 DE DE60014386T patent/DE60014386T2/de not_active Expired - Fee Related
- 2000-05-30 AT AT00935852T patent/ATE277922T1/de not_active IP Right Cessation
- 2000-06-01 PE PE2000000540A patent/PE20010291A1/es not_active Application Discontinuation
-
2003
- 2003-03-03 US US10/378,436 patent/US6624304B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000075132A1 (en) | 2000-12-14 |
| EP1198462B1 (en) | 2004-09-29 |
| JP2003501425A (ja) | 2003-01-14 |
| DE60014386T2 (de) | 2005-10-13 |
| DE60014386D1 (de) | 2004-11-04 |
| CA2375283A1 (en) | 2000-12-14 |
| AU5125200A (en) | 2000-12-28 |
| PE20010291A1 (es) | 2001-03-07 |
| EP1198462A1 (en) | 2002-04-24 |
| US6624304B1 (en) | 2003-09-23 |
| ES2228534T3 (es) | 2005-04-16 |
| US6570016B1 (en) | 2003-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |