ATE255882T1 - Liposomen-umschlossene polynukleotidzusammensetzung sowie verfahren - Google Patents

Liposomen-umschlossene polynukleotidzusammensetzung sowie verfahren

Info

Publication number
ATE255882T1
ATE255882T1 AT98930447T AT98930447T ATE255882T1 AT E255882 T1 ATE255882 T1 AT E255882T1 AT 98930447 T AT98930447 T AT 98930447T AT 98930447 T AT98930447 T AT 98930447T AT E255882 T1 ATE255882 T1 AT E255882T1
Authority
AT
Austria
Prior art keywords
liposomes
polynucleotide composition
polynucleotide
liposome
composition
Prior art date
Application number
AT98930447T
Other languages
German (de)
English (en)
Inventor
Theresa M Allen
Darrin Stuart
Original Assignee
Sequus Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequus Pharm Inc filed Critical Sequus Pharm Inc
Application granted granted Critical
Publication of ATE255882T1 publication Critical patent/ATE255882T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98930447T 1997-06-23 1998-06-22 Liposomen-umschlossene polynukleotidzusammensetzung sowie verfahren ATE255882T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5049097P 1997-06-23 1997-06-23
PCT/US1998/012937 WO1998058630A1 (en) 1997-06-23 1998-06-22 Liposome-entrapped polynucleotide composition and method

Publications (1)

Publication Number Publication Date
ATE255882T1 true ATE255882T1 (de) 2003-12-15

Family

ID=21965541

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98930447T ATE255882T1 (de) 1997-06-23 1998-06-22 Liposomen-umschlossene polynukleotidzusammensetzung sowie verfahren

Country Status (11)

Country Link
US (1) US6120798A (enExample)
EP (1) EP1017365B1 (enExample)
JP (1) JP2002508765A (enExample)
AT (1) ATE255882T1 (enExample)
AU (1) AU7983798A (enExample)
CA (1) CA2294579C (enExample)
DE (1) DE69820465T2 (enExample)
DK (1) DK1017365T3 (enExample)
ES (1) ES2212305T3 (enExample)
TW (1) TWI225412B (enExample)
WO (1) WO1998058630A1 (enExample)

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US7285288B1 (en) 1997-10-03 2007-10-23 Board Of Regents, The University Of Texas System Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides
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Also Published As

Publication number Publication date
US6120798A (en) 2000-09-19
WO1998058630A1 (en) 1998-12-30
JP2002508765A (ja) 2002-03-19
DE69820465T2 (de) 2004-09-16
ES2212305T3 (es) 2004-07-16
AU7983798A (en) 1999-01-04
EP1017365A1 (en) 2000-07-12
EP1017365B1 (en) 2003-12-10
CA2294579C (en) 2007-10-09
TWI225412B (en) 2004-12-21
HK1025906A1 (en) 2000-12-01
DE69820465D1 (de) 2004-01-22
DK1017365T3 (da) 2004-03-29
CA2294579A1 (en) 1998-12-30

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