ATE238269T1 - Antikrebs-platin-(vi)-komplexe zur oralen verabreichung - Google Patents
Antikrebs-platin-(vi)-komplexe zur oralen verabreichungInfo
- Publication number
- ATE238269T1 ATE238269T1 AT98961662T AT98961662T ATE238269T1 AT E238269 T1 ATE238269 T1 AT E238269T1 AT 98961662 T AT98961662 T AT 98961662T AT 98961662 T AT98961662 T AT 98961662T AT E238269 T1 ATE238269 T1 AT E238269T1
- Authority
- AT
- Austria
- Prior art keywords
- complexes
- oral administration
- platinum
- cancer
- cancer platinum
- Prior art date
Links
- VFVBGFGJGGQIPD-UHFFFAOYSA-N [Pt+6] Chemical class [Pt+6] VFVBGFGJGGQIPD-UHFFFAOYSA-N 0.000 title 1
- 230000001093 anti-cancer Effects 0.000 title 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- DDHUNHGZUHZNKB-UHFFFAOYSA-N 2,2-dimethylpropane-1,3-diamine Chemical compound NCC(C)(C)CN DDHUNHGZUHZNKB-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- XZAHJRZBUWYCBM-UHFFFAOYSA-N [1-(aminomethyl)cyclohexyl]methanamine Chemical compound NCC1(CN)CCCCC1 XZAHJRZBUWYCBM-UHFFFAOYSA-N 0.000 abstract 1
- HFAYPKGISTWLIZ-UHFFFAOYSA-N [4-(aminomethyl)oxan-4-yl]methanamine Chemical compound NCC1(CN)CCOCC1 HFAYPKGISTWLIZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000013522 chelant Substances 0.000 abstract 1
- 150000004985 diamines Chemical class 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- NDBYXKQCPYUOMI-UHFFFAOYSA-N platinum(4+) Chemical class [Pt+4] NDBYXKQCPYUOMI-UHFFFAOYSA-N 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/122—Propionic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
- C07C211/10—Diaminoethanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
- C07C211/11—Diaminopropanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
- C07C211/18—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing at least two amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/36—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/124—Acids containing four carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019970079743A KR100246722B1 (ko) | 1997-12-30 | 1997-12-30 | 경구용 백금 착화합물 항암제 및 그 제조방법 |
| PCT/KR1998/000456 WO1999033782A1 (en) | 1997-12-30 | 1998-12-23 | Anticancer platinum (iv) complexes for oral administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238269T1 true ATE238269T1 (de) | 2003-05-15 |
Family
ID=19530197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98961662T ATE238269T1 (de) | 1997-12-30 | 1998-12-23 | Antikrebs-platin-(vi)-komplexe zur oralen verabreichung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5998648A (de) |
| EP (1) | EP1051387B1 (de) |
| JP (1) | JP3648452B2 (de) |
| KR (2) | KR100246722B1 (de) |
| AT (1) | ATE238269T1 (de) |
| AU (1) | AU1693899A (de) |
| DE (1) | DE69813903T2 (de) |
| ES (1) | ES2196634T3 (de) |
| WO (1) | WO1999033782A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2266607A3 (de) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunokonjugate für Krebsbehandlung |
| RU2178702C1 (ru) * | 2001-02-21 | 2002-01-27 | Общество с ограниченной ответственностью "Нобель" | Антираковое средство |
| JP2007502777A (ja) * | 2003-08-13 | 2007-02-15 | ユニバーシティー オブ サウス フロリダ | 腫瘍の処置のための白金錯体 |
| US20050288365A1 (en) * | 2004-01-06 | 2005-12-29 | Heidi Kay | Platinum complexes and methods for inhibiting tumor cell proliferation |
| CZ2004964A3 (cs) * | 2004-09-14 | 2006-03-15 | Pliva-Lachema A. S. | Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo |
| CA2587779A1 (en) * | 2004-11-10 | 2007-01-18 | University Of South Florida | Platinum complexes for targeted drug delivery |
| KR100698609B1 (ko) * | 2005-05-06 | 2007-03-22 | 서울시립대학교 산학협력단 | 심지 급수형 화분 |
| WO2007006019A1 (en) * | 2005-07-06 | 2007-01-11 | University Of South Florida | Materials and methods for screening, diagnosis and prognosis of conditions associated with stat protein expression |
| DE602006017567D1 (de) * | 2005-09-12 | 2010-11-25 | Bendale N | Neues bioplatin, herstellungsverfahren, verfahren zur verabreichung einer antitumoralen behandlung |
| CZ300424B6 (cs) * | 2006-06-20 | 2009-05-13 | Pliva - Lachema A. S. | Farmaceutická kompozice pro perorální podání |
| EP2208731B1 (de) | 2009-06-26 | 2012-08-15 | Umicore AG & Co. KG | Verfahren zur Herstellung von 1,2-Diamino-Cyclohexan-Platin(II)-Komplexen |
| KR20240025177A (ko) | 2022-08-18 | 2024-02-27 | 정민우 | 왜곡현상을 방지하는 광학용 오목렌즈 및 광학용 오목렌즈 제조방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4996337A (en) * | 1987-06-23 | 1991-02-26 | American Cyanamid Company | Synthesis of cisplatin analogs |
| US4937358A (en) * | 1987-06-23 | 1990-06-26 | American Cyanamid Company | Synthesis of cisplatin analogs |
| EP0328274B1 (de) * | 1988-02-02 | 1994-10-19 | Johnson Matthey, Inc., | Pt(IV) Komplexe |
| US5072011A (en) * | 1988-02-02 | 1991-12-10 | Johnson Matthey, Inc. | Pt(IV) complexes |
| US5041578A (en) * | 1988-11-22 | 1991-08-20 | Board Of Regents, The University Of Texas System | Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents |
| JPH07138274A (ja) * | 1993-11-12 | 1995-05-30 | Tanaka Kikinzoku Kogyo Kk | Ｚ軸上に脂溶性基を有する抗腫瘍性シクロヘキサンジアミン誘導体白金（ｉｖ）錯体 |
| JPH07101970A (ja) * | 1993-10-04 | 1995-04-18 | Tanaka Kikinzoku Kogyo Kk | 抗腫瘍性シクロヘキサンジアミン誘導体の脂溶性新規白金（ｉｖ）錯体 |
| EP0646589A3 (de) * | 1993-10-04 | 1995-06-28 | Tanaka Precious Metal Ind | Anti-tumor Platin (IV) Komplexe. |
| WO1998000456A1 (en) * | 1996-07-02 | 1998-01-08 | Ciba Speciality Chemicals Holding Inc. | Process for curing a polymerizable composition |
| JPH10251285A (ja) * | 1997-03-14 | 1998-09-22 | Ss Pharmaceut Co Ltd | 白金（ｉｖ）錯体及びこれを含有する医薬 |
-
1997
- 1997-12-30 KR KR1019970079743A patent/KR100246722B1/ko not_active IP Right Cessation
-
1998
- 1998-08-14 US US09/134,697 patent/US5998648A/en not_active Expired - Fee Related
- 1998-12-23 JP JP2000526469A patent/JP3648452B2/ja not_active Expired - Fee Related
- 1998-12-23 WO PCT/KR1998/000456 patent/WO1999033782A1/en active IP Right Grant
- 1998-12-23 KR KR10-2000-7007188A patent/KR100377328B1/ko not_active IP Right Cessation
- 1998-12-23 AU AU16938/99A patent/AU1693899A/en not_active Abandoned
- 1998-12-23 ES ES98961662T patent/ES2196634T3/es not_active Expired - Lifetime
- 1998-12-23 AT AT98961662T patent/ATE238269T1/de not_active IP Right Cessation
- 1998-12-23 DE DE69813903T patent/DE69813903T2/de not_active Expired - Fee Related
- 1998-12-23 EP EP98961662A patent/EP1051387B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR100377328B1 (ko) | 2003-03-26 |
| ES2196634T3 (es) | 2003-12-16 |
| EP1051387A1 (de) | 2000-11-15 |
| KR100246722B1 (ko) | 2000-04-01 |
| US5998648A (en) | 1999-12-07 |
| EP1051387B1 (de) | 2003-04-23 |
| WO1999033782A1 (en) | 1999-07-08 |
| DE69813903D1 (de) | 2003-05-28 |
| JP3648452B2 (ja) | 2005-05-18 |
| JP2001527059A (ja) | 2001-12-25 |
| KR19990059535A (ko) | 1999-07-26 |
| KR20000064233A (ko) | 2000-11-06 |
| DE69813903T2 (de) | 2003-12-18 |
| AU1693899A (en) | 1999-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1051387 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |