|
US6770283B1
(en)
*
|
1990-12-13 |
2004-08-03 |
Bioption Ab |
DNA expression systems based on alphaviruses
|
|
US6015686A
(en)
*
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
EP0711829A3
(de)
*
|
1993-09-15 |
1997-07-09 |
Viagene Inc |
Rekombinanter Alphavirus Vektor
|
|
SE9401091D0
(sv)
*
|
1994-03-31 |
1994-03-31 |
Bioption Ab |
Alphavirus cDNA vectors
|
|
SE9401709D0
(sv)
*
|
1994-05-18 |
1994-05-18 |
Mathilda Sjoeberg |
Improved alphavirus vectors for expression of heterologous DNA
|
|
US5505947A
(en)
*
|
1994-05-27 |
1996-04-09 |
The University Of North Carolina At Chapel Hill |
Attenuating mutations in Venezuelan Equine Encephalitis virus
|
|
DE19512142A1
(de)
*
|
1995-03-31 |
1996-10-02 |
Immuno Ag |
Infektiöser cDNA-Klon des Tick-Borne Enzephalitis (TBE)-Virus, davon abgeleiteter rekombinanter Impfstoff und Herstellung desselben sowie ein pharmazeutisches Produkt, das eine replizierbare Nukleinsäure enthält
|
|
US5792462A
(en)
*
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US5639650A
(en)
*
|
1995-05-23 |
1997-06-17 |
The University Of North Carolina At Chapel Hill |
cDNA clone for South African Arbovirus No. 86
|
|
US6465634B1
(en)
|
1996-04-05 |
2002-10-15 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
US6451592B1
(en)
|
1996-04-05 |
2002-09-17 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
US5939262A
(en)
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
|
US5677124A
(en)
*
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
|
AU4737597A
(en)
|
1996-09-25 |
1998-04-17 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Retroviral packaging cassettes amplified in the cytoplasm by autocatalytic togavirus vectors
|
|
WO1998015636A1
(en)
*
|
1996-10-10 |
1998-04-16 |
Henrik Garoff |
Alphavirus-retrovirus vectors
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US5811407A
(en)
|
1997-02-19 |
1998-09-22 |
The University Of North Carolina At Chapel Hill |
System for the in vivo delivery and expression of heterologous genes in the bone marrow
|
|
US6432699B1
(en)
*
|
1997-03-28 |
2002-08-13 |
New York University |
Viral vectors having chimeric envelope proteins containing the IgG-binding domain of protein A
|
|
EP1025212B1
(de)
|
1997-10-14 |
2007-09-26 |
Darwin Molecular Corporation |
Thymidinkinase mutanten und fusionproteine mit thymidinkinase und guanylatekinase aktivitäten
|
|
EP1900818A3
(de)
|
1997-11-06 |
2008-06-11 |
Novartis Vaccines and Diagnostics S.r.l. |
Neissersche Antigene
|
|
CA2309826A1
(en)
|
1997-11-14 |
1999-05-27 |
Connaught Laboratories Limited |
Alphavirus vectors for paramyxovirus vaccines
|
|
WO1999036544A2
(en)
|
1998-01-14 |
1999-07-22 |
Chiron S.P.A. |
Neisseria meningitidis antigens
|
|
US6844188B1
(en)
|
1998-04-08 |
2005-01-18 |
University Of North Carolina At Chapel Hill |
Methods and modified cells for the treatment of cancer
|
|
AU754320B2
(en)
|
1998-04-08 |
2002-11-14 |
University Of North Carolina At Chapel Hill, The |
Methods and modified cells for the treatment of cancer
|
|
EP2261347A3
(de)
|
1998-05-01 |
2012-01-11 |
Novartis Vaccines and Diagnostics, Inc. |
Antigene und Zusammensetzungen gegen Neisseria meningitidis
|
|
WO1999058639A2
(en)
*
|
1998-05-08 |
1999-11-18 |
Akzo Nobel N.V. |
Structural proteins of fish pancreatic disease virus and uses thereof
|
|
JP2002527066A
(ja)
|
1998-10-15 |
2002-08-27 |
カイロン コーポレイション |
転移性乳癌および結腸癌調節遺伝子
|
|
PL192016B1
(pl)
*
|
1998-11-30 |
2006-08-31 |
Cytos Biotechnology Ag |
Kompozycja, sposób wytwarzania sztucznego, uporządkowanego i powtarzalnego układu antygenu, zastosowanie kompozycji oraz kompozycja szczepionki
|
|
EP1961813B1
(de)
|
1998-12-16 |
2011-08-10 |
Novartis Vaccines and Diagnostics, Inc. |
Menschliche Cyclin-abhängige Kinase (hPNQALRE)
|
|
DK1175497T3
(da)
*
|
1999-04-14 |
2010-05-31 |
Novartis Vaccines & Diagnostic |
Præparater og fremgangsmåder til generering af et immunrespons ved udnyttelse af alfavirusbaserede vektorsystemer
|
|
US8647864B2
(en)
|
1999-04-14 |
2014-02-11 |
Novartis Ag |
Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
|
|
CA2372235A1
(en)
|
1999-04-30 |
2000-11-09 |
Rino Rappuoli |
Conserved neisserial antigens
|
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
|
US6297013B1
(en)
|
1999-06-24 |
2001-10-02 |
Dnab Diagnostics Inc. |
Compositions and methods for determining the activity of DNA-binding proteins and of initiation of transcription
|
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
|
AU1013601A
(en)
|
1999-10-22 |
2001-05-08 |
Aventis Pasteur Limited |
Method of inducing and/or enhancing an immune response to tumor antigens
|
|
WO2001031046A1
(en)
|
1999-10-26 |
2001-05-03 |
International Aids Vaccine Initiative |
Invasive bacterial vectors for expressing alphavirus replicons
|
|
EP1226253A2
(de)
|
1999-10-29 |
2002-07-31 |
Chiron S.P.A. |
Antigene peptide aus neisseria
|
|
JP2003516731A
(ja)
|
1999-11-18 |
2003-05-20 |
カイロン コーポレイション |
ヒトfgf−21遺伝子および遺伝子発現産物
|
|
CA2871789C
(en)
|
2000-01-17 |
2017-04-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
|
|
EP1261638A2
(de)
|
2000-03-08 |
2002-12-04 |
Chiron Corporation |
Humanes fgf-23 gen und genexpressionsprodukte
|
|
WO2001085208A2
(en)
|
2000-05-05 |
2001-11-15 |
Cytos Biotechnology Ag |
Molecular antigen arrays and vaccines
|
|
ATE346925T1
(de)
*
|
2000-05-10 |
2006-12-15 |
Sanofi Pasteur Ltd |
Durch mage minigene kodierte immunogene polypeptide und ihre verwendungen
|
|
AU2001275191A1
(en)
*
|
2000-05-31 |
2001-12-11 |
Chiron Corporation |
Method for the purification of alphavirus replicon particles
|
|
US6783939B2
(en)
|
2000-07-07 |
2004-08-31 |
Alphavax, Inc. |
Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
|
|
US6982087B2
(en)
|
2000-09-07 |
2006-01-03 |
The University Of North Carolina At Chapel Hill |
Vectors derived from South African Arbovirus No. 86
|
|
ATE439372T1
(de)
|
2000-10-27 |
2009-08-15 |
Novartis Vaccines & Diagnostic |
Nukleinsäuren und proteine von gruppen a und b- streptokokken
|
|
JP4394878B2
(ja)
|
2000-12-08 |
2010-01-06 |
ライフ テクノロジーズ コーポレーション |
複数の認識部位を用いた核酸分子合成のための方法および組成物
|
|
US7094409B2
(en)
*
|
2001-01-19 |
2006-08-22 |
Cytos Biotechnology Ag |
Antigen arrays for treatment of allergic eosinophilic diseases
|
|
US7320793B2
(en)
*
|
2001-01-19 |
2008-01-22 |
Cytos Biotechnology Ag |
Molecular antigen array
|
|
US7128911B2
(en)
|
2001-01-19 |
2006-10-31 |
Cytos Biotechnology Ag |
Antigen arrays for treatment of bone disease
|
|
GB0107661D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Staphylococcus aureus
|
|
GB0107658D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Streptococcus pneumoniae
|
|
JP5089847B2
(ja)
*
|
2001-03-27 |
2012-12-05 |
ニューヨーク・ユニバーシティ |
アルファウイルスに基づく高親和性ラミニン受容体標的化ベクターを用いた腫瘍の治療
|
|
AU2002305151A1
(en)
|
2001-04-06 |
2002-10-21 |
Georgetown University |
Gene scc-112 and diagnostic and therapeutic uses thereof
|
|
WO2002081642A2
(en)
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene brcc-3 and diagnostic and therapeutic uses thereof
|
|
AU2002303261A1
(en)
|
2001-04-06 |
2002-10-21 |
Georgetown University |
Gene brcc2 and diagnostic and therapeutic uses thereof
|
|
EP1903054A3
(de)
|
2001-06-05 |
2008-07-23 |
CureVac GmbH |
Stabilisierte mRNA mit erhöhtem G/C-Gehalt und optimierter Codon Usage für die Gentherapie
|
|
US7045335B2
(en)
*
|
2001-09-06 |
2006-05-16 |
Alphavax, Inc. |
Alphavirus replicon vector systems
|
|
US7115266B2
(en)
*
|
2001-10-05 |
2006-10-03 |
Cytos Biotechnology Ag |
Angiotensin peptide-carrier conjugates and uses thereof
|
|
MXPA04002644A
(es)
|
2001-10-05 |
2004-07-08 |
Cytos Biotechnology Ag |
Conjugados que portan un peptido de angiotensina y usos de los mismos.
|
|
EP2168596B1
(de)
|
2001-12-12 |
2012-05-23 |
Novartis Vaccines and Diagnostics S.r.l. |
Immunisierung gegen Chlamydia trachomatis
|
|
US7877273B2
(en)
*
|
2002-01-08 |
2011-01-25 |
Fredric David Abramson |
System and method for evaluating and providing nutrigenomic data, information and advice
|
|
US20030219459A1
(en)
*
|
2002-01-18 |
2003-11-27 |
Cytos Biotechnology Ag |
Prion protein carrier-conjugates
|
|
MXPA04008890A
(es)
|
2002-03-15 |
2005-10-18 |
Wyeth Corp |
Mutantes de la proteina p4 de haemophilus influenzae no tipicable con actividad enzimatica reducida.
|
|
ATE369895T1
(de)
|
2002-04-09 |
2007-09-15 |
Sanofi Pasteur Ltd |
Modifizierte cea nucleinsäure und expressionsvektoren
|
|
US7244565B2
(en)
|
2002-04-10 |
2007-07-17 |
Georgetown University |
Gene shinc-3 and diagnostic and therapeutic uses thereof
|
|
US7138512B2
(en)
|
2002-04-10 |
2006-11-21 |
Georgetown University |
Gene SHINC-2 and diagnostic and therapeutic uses thereof
|
|
BR0311995A
(pt)
*
|
2002-06-20 |
2005-04-05 |
Cytos Biotechnology Ag |
Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso
|
|
JP4726483B2
(ja)
|
2002-07-17 |
2011-07-20 |
サイトス バイオテクノロジー アーゲー |
分子抗原アレイ
|
|
KR101228376B1
(ko)
*
|
2002-07-18 |
2013-01-31 |
사이토스 바이오테크놀로지 아게 |
합텐-캐리어 컨쥬게이트 및 그의 용도
|
|
DE60336902D1
(de)
|
2002-07-19 |
2011-06-09 |
Cytos Biotechnology Ag |
Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays
|
|
AU2003284239B2
(en)
|
2002-10-21 |
2008-08-21 |
Eisai Inc. |
Compositions and methods for treating human papillomavirus-mediated disease
|
|
WO2004046177A2
(en)
|
2002-11-15 |
2004-06-03 |
Chiron Srl |
Unexpected surface proteins in neisseria meningitidis
|
|
EP1585812B1
(de)
|
2002-12-13 |
2017-01-18 |
Alphavax, Inc. |
Multiantigene alphavirusrepliconpartikel und verfahren
|
|
JP5079981B2
(ja)
|
2002-12-13 |
2012-11-21 |
アルファバックス,インコーポレイティド |
アルファウイルス粒子及び調製方法
|
|
WO2004063342A2
(en)
*
|
2003-01-09 |
2004-07-29 |
Invitrogen Corporation |
Cellular delivery and activation polypeptide-nucleic acid complexes
|
|
KR101518309B1
(ko)
*
|
2003-03-20 |
2015-05-08 |
알파벡스, 인크. |
개선된 알파바이러스 레플리콘 및 헬퍼 구축물
|
|
GB0308198D0
(en)
|
2003-04-09 |
2003-05-14 |
Chiron Srl |
ADP-ribosylating bacterial toxin
|
|
EP1623229A2
(de)
*
|
2003-05-15 |
2006-02-08 |
Cytos Biotechnology AG |
Selektion von b-zellen mit gewünschter spezifität: verfahren zur herstellung und deren verwendung
|
|
EP1651666B1
(de)
|
2003-07-11 |
2009-05-27 |
Alphavax, Inc. |
Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
|
|
US7910093B2
(en)
|
2003-08-19 |
2011-03-22 |
New York University |
Method for detecting cancer cells and monitoring cancer therapy
|
|
US8562970B2
(en)
*
|
2003-10-08 |
2013-10-22 |
Sanofi Pasteur Limited |
Modified CEA/B7 vector
|
|
CN1905903A
(zh)
*
|
2004-01-20 |
2007-01-31 |
赛托斯生物技术公司 |
生长素释放肽-载体偶联物
|
|
US8268324B2
(en)
|
2004-03-29 |
2012-09-18 |
Galpharma Co., Ltd. |
Modified galectin 9 proteins and use thereof
|
|
ES2321212T3
(es)
|
2004-05-18 |
2009-06-03 |
Alphavax, Inc. |
Vectores alfavirus derivados de tc-83, particulas y metodos antecentes de la invencion.
|
|
ES2292271B1
(es)
*
|
2004-05-20 |
2009-02-16 |
Proyecto De Biomedicina Cima, S.L. |
Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales.
|
|
JP2008501658A
(ja)
*
|
2004-06-02 |
2008-01-24 |
サイトス バイオテクノロジー アーゲー |
非ヒトtnf−ペプチドの担体コンジュゲートの医学上の使用
|
|
US7189540B2
(en)
*
|
2004-06-21 |
2007-03-13 |
Quattromed As |
Optimized recognition site of the alphavirus non-structural protease for tag removal and specific processing of recombinant proteins
|
|
US7862829B2
(en)
*
|
2004-07-09 |
2011-01-04 |
University Of North Carolina At Chapel Hill |
Viral adjuvants
|
|
US7998733B2
(en)
|
2004-10-05 |
2011-08-16 |
Merial Limited |
Chimeric vectors
|
|
WO2007046839A2
(en)
*
|
2005-02-15 |
2007-04-26 |
University Of North Carolina At Chapel Hill |
New live virus vaccines
|
|
EP3312196B1
(de)
|
2005-03-23 |
2019-07-17 |
Genmab A/S |
Antikörper gegen cd38 zur behandlung von multiplem myelom
|
|
US7303898B2
(en)
*
|
2005-03-29 |
2007-12-04 |
New York University |
Defective sindbis viral vectors
|
|
ATE522541T1
(de)
|
2006-06-09 |
2011-09-15 |
Novartis Ag |
Bakterielle adhäsine konformere
|
|
ES2517869T3
(es)
|
2006-09-12 |
2014-11-04 |
Alphavax, Inc. |
Partículas de replicones de alfavirus emparejadas con antígenos proteicos como adyuvantes inmunológicos
|
|
AU2007342333B2
(en)
|
2006-09-12 |
2013-02-28 |
Alphavax, Inc. |
Alphavirus replicon particles encoding IL- 12 as immunological adjuvants
|
|
CA2668417A1
(en)
*
|
2006-11-03 |
2008-05-15 |
Alphavax, Inc. |
Alphavirus and alphavirus replicon particle formulations and methods
|
|
EP2139447A2
(de)
|
2007-03-20 |
2010-01-06 |
Harold Brem |
Gm-csf-kosmezeutikazusammensetzungen und verfahren zu ihrer verwendung
|
|
DK2183368T3
(en)
|
2007-06-21 |
2016-09-05 |
Alphavax Inc |
PROMOTER-FREE CASES FOR EXPRESSION OF ALPHAVIRUS STRUCTURE PROTEINS
|
|
PT2222697E
(pt)
|
2007-11-01 |
2013-02-15 |
Perseid Therapeutics Llc |
Polipeptídeos imunossupressores e ácidos nucleicos
|
|
US8680258B2
(en)
|
2008-12-01 |
2014-03-25 |
Alphavax, Inc. |
Use of microRNAs to control virus helper nucleic acids
|
|
US20120128714A1
(en)
|
2009-04-08 |
2012-05-24 |
Wolchok Jedd D |
Alphavirus Replicon Particles Expressing TRP2
|
|
US8563261B2
(en)
|
2009-09-28 |
2013-10-22 |
The Trustees Of The University Of Pennsylvania |
Method of diagnosing and treating interstitial cystitis
|
|
EE05711B1
(et)
|
2009-10-07 |
2014-04-15 |
Tartu Ülikool |
Meetod ja kompositsioon konditsionaalselt letaalsete viirusmutantide loomiseks ja eukarootse raku elulisuse k?rvaldamiseks
|
|
WO2011064437A2
(es)
|
2009-11-26 |
2011-06-03 |
Proyecto De Biomedicina Cima, S.L. |
Vectores virales y procedimientos útiles en la preparación de gdnf
|
|
WO2011119920A2
(en)
|
2010-03-25 |
2011-09-29 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
|
US9198975B2
(en)
|
2010-12-01 |
2015-12-01 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeting sites of neovascular growth
|
|
US20140093556A1
(en)
|
2011-01-28 |
2014-04-03 |
Sanofi Pasteur Sa |
Immunological Compositions Against HIV
|
|
SMT201800284T1
(it)
|
2011-06-10 |
2018-07-17 |
Univ Oregon Health & Science |
Glicoproteine cmv e vettori ricombinanti
|
|
EP2568289A3
(de)
|
2011-09-12 |
2013-04-03 |
International AIDS Vaccine Initiative |
Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
|
|
EP2586461A1
(de)
|
2011-10-27 |
2013-05-01 |
Christopher L. Parks |
Von einem eingehüllten Virus abgeleitete Virenpartikel
|
|
ES2631608T3
(es)
|
2012-06-27 |
2017-09-01 |
International Aids Vaccine Initiative |
Variante de la glicoproteína Env del VIH-1
|
|
WO2014140938A2
(en)
|
2013-03-14 |
2014-09-18 |
Centre Hospitalier Universitaire Vaudois |
Immunological methods
|
|
EP2848937A1
(de)
|
2013-09-05 |
2015-03-18 |
International Aids Vaccine Initiative |
Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
|
|
EP2873423B1
(de)
|
2013-10-07 |
2017-05-31 |
International Aids Vaccine Initiative |
Lösliche hiv-1-hüllglykoproteintrimere
|
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
US9931394B2
(en)
|
2015-03-23 |
2018-04-03 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
US20190282679A1
(en)
*
|
2016-04-18 |
2019-09-19 |
Rima McLeod |
Toxoplasma gondii vaccines and their use
|
|
ES2925083T3
(es)
*
|
2017-02-27 |
2022-10-13 |
Translate Bio Inc |
Métodos de purificación de ARN mensajero
|
|
US11926817B2
(en)
|
2019-08-09 |
2024-03-12 |
Nutcracker Therapeutics, Inc. |
Microfluidic apparatus and methods of use thereof
|
|
JP2026502453A
(ja)
|
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