|
US6770283B1
(en)
*
|
1990-12-13 |
2004-08-03 |
Bioption Ab |
DNA expression systems based on alphaviruses
|
|
US6015686A
(en)
*
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
WO1995007994A2
(en)
|
1993-09-15 |
1995-03-23 |
Viagene, Inc. |
Recombinant alphavirus vectors
|
|
SE9401091D0
(sv)
|
1994-03-31 |
1994-03-31 |
Bioption Ab |
Alphavirus cDNA vectors
|
|
SE9401709D0
(sv)
|
1994-05-18 |
1994-05-18 |
Mathilda Sjoeberg |
Improved alphavirus vectors for expression of heterologous DNA
|
|
US5505947A
(en)
*
|
1994-05-27 |
1996-04-09 |
The University Of North Carolina At Chapel Hill |
Attenuating mutations in Venezuelan Equine Encephalitis virus
|
|
DE19512142A1
(de)
*
|
1995-03-31 |
1996-10-02 |
Immuno Ag |
Infektiöser cDNA-Klon des Tick-Borne Enzephalitis (TBE)-Virus, davon abgeleiteter rekombinanter Impfstoff und Herstellung desselben sowie ein pharmazeutisches Produkt, das eine replizierbare Nukleinsäure enthält
|
|
US5792462A
(en)
*
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US5639650A
(en)
*
|
1995-05-23 |
1997-06-17 |
The University Of North Carolina At Chapel Hill |
cDNA clone for South African Arbovirus No. 86
|
|
US6451592B1
(en)
|
1996-04-05 |
2002-09-17 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
US6458560B1
(en)
|
1996-04-05 |
2002-10-01 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
US5939262A
(en)
*
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
|
US5677124A
(en)
*
|
1996-07-03 |
1997-10-14 |
Ambion, Inc. |
Ribonuclease resistant viral RNA standards
|
|
WO1998013511A1
(en)
*
|
1996-09-25 |
1998-04-02 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Retroviral packaging cassettes amplified in the cytoplasm by autocatalytic togavirus vectors
|
|
AU729690B2
(en)
*
|
1996-10-10 |
2001-02-08 |
Henrik Garoff |
Alphavirus-retrovirus vectors
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US5811407A
(en)
*
|
1997-02-19 |
1998-09-22 |
The University Of North Carolina At Chapel Hill |
System for the in vivo delivery and expression of heterologous genes in the bone marrow
|
|
US6432699B1
(en)
|
1997-03-28 |
2002-08-13 |
New York University |
Viral vectors having chimeric envelope proteins containing the IgG-binding domain of protein A
|
|
CA2306443A1
(en)
|
1997-10-14 |
1999-04-22 |
Darwin Molecular Corporation |
Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
|
|
BR9813930A
(pt)
|
1997-11-06 |
2006-12-19 |
Chiron Spa |
antìgeno neisserial
|
|
AU749345B2
(en)
|
1997-11-14 |
2002-06-27 |
Connaught Laboratories Limited |
Alphavirus vectors for paramyxovirus vaccines
|
|
ATE446368T1
(de)
|
1998-01-14 |
2009-11-15 |
Novartis Vaccines & Diagnostic |
Antigene aus neisseria meningitidis
|
|
US6844188B1
(en)
|
1998-04-08 |
2005-01-18 |
University Of North Carolina At Chapel Hill |
Methods and modified cells for the treatment of cancer
|
|
CA2327835C
(en)
|
1998-04-08 |
2010-09-21 |
University Of North Carolina At Chapel Hill |
Methods and modified cells for the treatment of cancer
|
|
MX343752B
(es)
|
1998-05-01 |
2016-11-22 |
Novartis Vaccines & Diagnostics Inc |
Antigenos de neisseria meningitidis y composiciones que los contienen.
|
|
JP4323720B2
(ja)
*
|
1998-05-08 |
2009-09-02 |
インターベツト・インターナシヨナル・ベー・ベー |
魚膵臓病ウイルス構造タンパク質およびその使用
|
|
EP1121437B1
(de)
|
1998-10-15 |
2008-02-20 |
Novartis Vaccines and Diagnostics, Inc. |
Gene mit veränderter expression in metastatischen brust- oder dickdarm- krebszellen
|
|
MXPA01005389A
(es)
*
|
1998-11-30 |
2003-03-27 |
Cytos Biotechnology Ag |
Presentacion molecular ordenada de antigenos, metodos de preparacion y uso.
|
|
DK1141331T3
(da)
|
1998-12-16 |
2009-01-05 |
Novartis Vaccines & Diagnostic |
Human cyclinafhængig kinase (hPNQALRE)
|
|
US8647864B2
(en)
|
1999-04-14 |
2014-02-11 |
Novartis Ag |
Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
|
|
CA2373300C
(en)
|
1999-04-14 |
2012-02-21 |
Chiron Corporation |
Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
|
|
NZ571167A
(en)
|
1999-04-30 |
2010-05-28 |
Novartis Vaccines & Diagnostic |
Fragments from Neisseria protein ORF 953 and their use in medicaments and diagnostic reagents
|
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
|
US6297013B1
(en)
|
1999-06-24 |
2001-10-02 |
Dnab Diagnostics Inc. |
Compositions and methods for determining the activity of DNA-binding proteins and of initiation of transcription
|
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
|
CA2388301C
(en)
|
1999-10-22 |
2011-01-04 |
Aventis Pasteur Limited |
Modified gp100 and uses thereof
|
|
JP2003512077A
(ja)
*
|
1999-10-26 |
2003-04-02 |
インターナショナル エイズ バクシーン イニシアティブ |
アルファウイルスレプリコンを発現する侵襲性細菌
|
|
PT2275551E
(pt)
|
1999-10-29 |
2015-06-29 |
Novartis Vaccines & Diagnostic |
Péptidos antigénicos de neisseria
|
|
PT1232264E
(pt)
|
1999-11-18 |
2009-11-26 |
Novartis Vaccines & Diagnostic |
Gene fgf-21 humano e produtos da expressão do gene
|
|
ES2588917T3
(es)
|
2000-01-17 |
2016-11-07 |
Glaxosmithkline Biologicals Sa |
Vacuna de VME suplementada contra meningococo
|
|
WO2001066595A2
(en)
|
2000-03-08 |
2001-09-13 |
Chiron Corporation |
Human fgf-23 gene and gene expression products
|
|
EP1278542A2
(de)
|
2000-05-05 |
2003-01-29 |
Cytos Biotechnology AG |
Molekuläre antigenarrays und impfstoffe
|
|
US7851212B2
(en)
|
2000-05-10 |
2010-12-14 |
Sanofi Pasteur Limited |
Immunogenic polypeptides encoded by MAGE minigenes and uses thereof
|
|
US6767699B2
(en)
|
2000-05-31 |
2004-07-27 |
Chiron Corporation |
Method for the quantitation of alphavirus replicon particles
|
|
US6783939B2
(en)
|
2000-07-07 |
2004-08-31 |
Alphavax, Inc. |
Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
|
|
WO2002020721A2
(en)
*
|
2000-09-07 |
2002-03-14 |
University Of North Carolina At Chapel Hill |
Vectors derived from south african arbovirus no. 86
|
|
US7939087B2
(en)
|
2000-10-27 |
2011-05-10 |
Novartis Vaccines And Diagnostics, Inc. |
Nucleic acids and proteins from Streptococcus groups A & B
|
|
EP2105496B1
(de)
|
2000-12-08 |
2013-02-20 |
Life Technologies Corporation |
Verfahren und Zusammensetzungen zur Synthese von Nukleinsäuremolekülen unter Verwendung multipler Erkennungsstellen
|
|
US7128911B2
(en)
|
2001-01-19 |
2006-10-31 |
Cytos Biotechnology Ag |
Antigen arrays for treatment of bone disease
|
|
US7094409B2
(en)
*
|
2001-01-19 |
2006-08-22 |
Cytos Biotechnology Ag |
Antigen arrays for treatment of allergic eosinophilic diseases
|
|
US7264810B2
(en)
*
|
2001-01-19 |
2007-09-04 |
Cytos Biotechnology Ag |
Molecular antigen array
|
|
CA2440890C
(en)
*
|
2001-03-27 |
2011-07-19 |
New York University |
Tumor therapy with alphavirus-based and high affinity laminin receptor-targeted vectors
|
|
GB0107661D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Staphylococcus aureus
|
|
GB0107658D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Streptococcus pneumoniae
|
|
WO2002081641A2
(en)
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene scc-112 and diagnostic and therapeutic uses thereof
|
|
WO2002081642A2
(en)
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene brcc-3 and diagnostic and therapeutic uses thereof
|
|
AU2002303261A1
(en)
|
2001-04-06 |
2002-10-21 |
Georgetown University |
Gene brcc2 and diagnostic and therapeutic uses thereof
|
|
ATE291925T1
(de)
|
2001-06-05 |
2005-04-15 |
Curevac Gmbh |
Stabilisierte mrna mit erhöhtem g/c-gehalt und optimierter codon usage für die gentherapie
|
|
WO2003023026A1
(en)
|
2001-09-06 |
2003-03-20 |
Alphavax, Inc. |
Alphavirus replicon vector systems
|
|
US7115266B2
(en)
*
|
2001-10-05 |
2006-10-03 |
Cytos Biotechnology Ag |
Angiotensin peptide-carrier conjugates and uses thereof
|
|
MXPA04002644A
(es)
|
2001-10-05 |
2004-07-08 |
Cytos Biotechnology Ag |
Conjugados que portan un peptido de angiotensina y usos de los mismos.
|
|
ES2386386T3
(es)
|
2001-12-12 |
2012-08-20 |
Novartis Vaccines And Diagnostics S.R.L. |
Inmunización contra Chlamydia trachomatis
|
|
US7877273B2
(en)
*
|
2002-01-08 |
2011-01-25 |
Fredric David Abramson |
System and method for evaluating and providing nutrigenomic data, information and advice
|
|
US20030219459A1
(en)
*
|
2002-01-18 |
2003-11-27 |
Cytos Biotechnology Ag |
Prion protein carrier-conjugates
|
|
CA2479118A1
(en)
|
2002-03-15 |
2003-09-25 |
Wyeth Holdings Corporation |
Mutants of the p4 protein of nontypable haemophilus influenzae with reduced enzymatic activity
|
|
ATE369895T1
(de)
|
2002-04-09 |
2007-09-15 |
Sanofi Pasteur Ltd |
Modifizierte cea nucleinsäure und expressionsvektoren
|
|
WO2005035773A2
(en)
*
|
2003-10-08 |
2005-04-21 |
Sanofi Pasteur, Inc. |
Modified cea /b7 vector
|
|
US7138512B2
(en)
|
2002-04-10 |
2006-11-21 |
Georgetown University |
Gene SHINC-2 and diagnostic and therapeutic uses thereof
|
|
US7244565B2
(en)
|
2002-04-10 |
2007-07-17 |
Georgetown University |
Gene shinc-3 and diagnostic and therapeutic uses thereof
|
|
ATE489969T1
(de)
*
|
2002-06-20 |
2010-12-15 |
Cytos Biotechnology Ag |
Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung
|
|
AU2003246690B2
(en)
|
2002-07-17 |
2010-03-11 |
Cytos Biotechnology Ag |
Molecular antigen arrays using a virus like particle derived from the AP205 coat protein
|
|
NZ537003A
(en)
*
|
2002-07-18 |
2008-03-28 |
Cytos Biotechnology Ag |
Hapten-carrier conjugates comprising virus like particles and uses thereof
|
|
BR0312792A
(pt)
|
2002-07-19 |
2005-05-03 |
Cytos Biotechnology Ag |
Composições de vacinas contendo séries antigênicas de amilóide beta1-6
|
|
AU2003284239B2
(en)
|
2002-10-21 |
2008-08-21 |
Eisai Inc. |
Compositions and methods for treating human papillomavirus-mediated disease
|
|
CA2506318C
(en)
|
2002-11-15 |
2011-07-12 |
Chiron Srl |
Unexpected surface proteins in neisseria meningitidis
|
|
AU2003297041B2
(en)
|
2002-12-13 |
2009-02-26 |
Alphavax, Inc. |
Alphavirus particles and methods for preparation
|
|
AU2003297039B2
(en)
*
|
2002-12-13 |
2009-03-05 |
Alphavax, Inc. |
Multi-antigenic alphavirus replicon particles and methods
|
|
CA2513072A1
(en)
*
|
2003-01-09 |
2004-07-29 |
Invitrogen Corporation |
Cellular delivery and activation polypeptide-nucleic acid complexes
|
|
EP1608762B1
(de)
|
2003-03-20 |
2014-01-08 |
Alphavax, Inc. |
Verbesserte alphavirus replikons und helferkonstrukt
|
|
GB0308198D0
(en)
|
2003-04-09 |
2003-05-14 |
Chiron Srl |
ADP-ribosylating bacterial toxin
|
|
WO2004102198A2
(en)
*
|
2003-05-15 |
2004-11-25 |
Cytos Biotechnology Ag |
Selection of b cells with specificity of interest: method of preparation and use
|
|
PT1651666E
(pt)
*
|
2003-07-11 |
2009-08-28 |
Alphavax Inc |
Vacinas de citomegalovírus à base de alfavírus
|
|
US7910093B2
(en)
|
2003-08-19 |
2011-03-22 |
New York University |
Method for detecting cancer cells and monitoring cancer therapy
|
|
EP1706152A2
(de)
*
|
2004-01-20 |
2006-10-04 |
Cytos Biotechnology AG |
Partikelinduzierte ghrelin-immunantwort
|
|
KR101222281B1
(ko)
|
2004-03-29 |
2013-01-28 |
가르파마 컴퍼니 리미티드 |
신규 갈렉틴 9 개변체 단백질 및 그 용도
|
|
PT1751289E
(pt)
|
2004-05-18 |
2009-03-31 |
Alphavax Inc |
Vectores de alfavirais derivados da tc-83, partículas e métodos
|
|
ES2292271B1
(es)
*
|
2004-05-20 |
2009-02-16 |
Proyecto De Biomedicina Cima, S.L. |
Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales.
|
|
KR20070058426A
(ko)
*
|
2004-06-02 |
2007-06-08 |
사이토스 바이오테크놀로지 아게 |
비-인간 tnf-펩티드의 담체 콘쥬게이트의 의학적 용도
|
|
US7189540B2
(en)
*
|
2004-06-21 |
2007-03-13 |
Quattromed As |
Optimized recognition site of the alphavirus non-structural protease for tag removal and specific processing of recombinant proteins
|
|
AU2005327198B2
(en)
|
2004-07-09 |
2011-03-31 |
University Of North Carolina At Chapel Hill |
Viral adjuvants
|
|
US7998733B2
(en)
|
2004-10-05 |
2011-08-16 |
Merial Limited |
Chimeric vectors
|
|
EP1856250B1
(de)
*
|
2005-02-15 |
2013-07-24 |
The University of North Carolina At Chapel Hill |
Neue lebende virus-impfstoffe
|
|
EP2551282A3
(de)
|
2005-03-23 |
2013-02-13 |
Genmab A/S |
Antikörper gegen CD38 zur Behandling von multiplem Myelom
|
|
US7303898B2
(en)
*
|
2005-03-29 |
2007-12-04 |
New York University |
Defective sindbis viral vectors
|
|
DK2054431T3
(da)
|
2006-06-09 |
2012-01-02 |
Novartis Ag |
Konformere af bakterielle adhæsiner
|
|
US20090022760A1
(en)
|
2006-09-12 |
2009-01-22 |
Alphavax |
Alphavirus Replicon Particles Matched to Protein Antigens as Immunological Adjuvants
|
|
AU2007342333B2
(en)
|
2006-09-12 |
2013-02-28 |
Alphavax, Inc. |
Alphavirus replicon particles encoding IL- 12 as immunological adjuvants
|
|
US20090047255A1
(en)
|
2006-11-03 |
2009-02-19 |
Alphavax, Inc. |
Alphavirus and Alphavirus Replicon Particle Formulations and Methods
|
|
EP2139447A2
(de)
|
2007-03-20 |
2010-01-06 |
Harold Brem |
Gm-csf-kosmezeutikazusammensetzungen und verfahren zu ihrer verwendung
|
|
DK2947149T3
(en)
|
2007-06-21 |
2018-06-06 |
Alphavax Inc |
ALPHAVIRUS REPLICATION PARTICLES FOR USE IN VACCINATION
|
|
CA2703263C
(en)
|
2007-11-01 |
2014-03-18 |
Perseid Therapeutics Llc |
Immunosuppressive polypeptides and nucleic acids
|
|
US8680258B2
(en)
|
2008-12-01 |
2014-03-25 |
Alphavax, Inc. |
Use of microRNAs to control virus helper nucleic acids
|
|
AU2010234362B2
(en)
|
2009-04-08 |
2015-11-26 |
Alphavax, Inc. |
Alphavirus replicon particles expressing TRP2
|
|
US8563261B2
(en)
|
2009-09-28 |
2013-10-22 |
The Trustees Of The University Of Pennsylvania |
Method of diagnosing and treating interstitial cystitis
|
|
EE05711B1
(et)
|
2009-10-07 |
2014-04-15 |
Tartu Ülikool |
Meetod ja kompositsioon konditsionaalselt letaalsete viirusmutantide loomiseks ja eukarootse raku elulisuse k?rvaldamiseks
|
|
WO2011064437A2
(es)
|
2009-11-26 |
2011-06-03 |
Proyecto De Biomedicina Cima, S.L. |
Vectores virales y procedimientos útiles en la preparación de gdnf
|
|
WO2011119920A2
(en)
|
2010-03-25 |
2011-09-29 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
|
EP2698635A3
(de)
|
2010-12-01 |
2014-05-28 |
The University Of North Carolina At Chapel Hill |
Verfahren und Zusammensetzungen zum Targeting auf Stellen neovaskulären Wachstums
|
|
EP2668201A2
(de)
|
2011-01-28 |
2013-12-04 |
Sanofi Pasteur SA |
Immunologische zusammensetzungen mit hiv-gp41-polypeptidderivaten
|
|
ES2667425T3
(es)
|
2011-06-10 |
2018-05-10 |
Oregon Health & Science University |
Glucoproteínas y vectores recombinantes de CMV
|
|
AU2012216792A1
(en)
|
2011-09-12 |
2013-03-28 |
International Aids Vaccine Initiative |
Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
|
|
EP2586461A1
(de)
|
2011-10-27 |
2013-05-01 |
Christopher L. Parks |
Von einem eingehüllten Virus abgeleitete Virenpartikel
|
|
EP2679596B1
(de)
|
2012-06-27 |
2017-04-12 |
International Aids Vaccine Initiative |
HIV-1 Env-proteinvariante
|
|
WO2014140938A2
(en)
|
2013-03-14 |
2014-09-18 |
Centre Hospitalier Universitaire Vaudois |
Immunological methods
|
|
US20150065381A1
(en)
|
2013-09-05 |
2015-03-05 |
International Aids Vaccine Initiative |
Methods of identifying novel hiv-1 immunogens
|
|
EP2873423B1
(de)
|
2013-10-07 |
2017-05-31 |
International Aids Vaccine Initiative |
Lösliche hiv-1-hüllglykoproteintrimere
|
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
|
EP3072901A1
(de)
|
2015-03-23 |
2016-09-28 |
International Aids Vaccine Initiative |
Lösliche hiv-1-hüllglykoproteintrimere
|
|
US20190282679A1
(en)
*
|
2016-04-18 |
2019-09-19 |
Rima McLeod |
Toxoplasma gondii vaccines and their use
|
|
IL268856B2
(en)
|
2017-02-27 |
2024-09-01 |
Translate Bio Inc |
Methods for purification of messenger rna
|
|
EP4010481A4
(de)
|
2019-08-09 |
2023-09-20 |
Nutcracker Therapeutics, Inc. |
Mikrofluidische vorrichtungen und verfahren zur verwendung davon
|
|
AU2024208643A1
(en)
|
2023-01-12 |
2025-06-26 |
Bavarian Nordic A/S |
RECOMBINANT MODIFIED saRNA (VRP) FOR CANCER VACCINE
|