ATE231862T1 - Tetrahydropyridoether - Google Patents

Tetrahydropyridoether

Info

Publication number
ATE231862T1
ATE231862T1 AT99948776T AT99948776T ATE231862T1 AT E231862 T1 ATE231862 T1 AT E231862T1 AT 99948776 T AT99948776 T AT 99948776T AT 99948776 T AT99948776 T AT 99948776T AT E231862 T1 ATE231862 T1 AT E231862T1
Authority
AT
Austria
Prior art keywords
tetrahydropyridoether
naphthyridine
imidazo
methoxyethoxy
tetrahydro
Prior art date
Application number
AT99948776T
Other languages
German (de)
English (en)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Ernst Sturm
Joerg Senn-Bilfinger
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE231862T1 publication Critical patent/ATE231862T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT99948776T 1998-09-23 1999-09-17 Tetrahydropyridoether ATE231862T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
PCT/EP1999/006899 WO2000017200A1 (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Publications (1)

Publication Number Publication Date
ATE231862T1 true ATE231862T1 (de) 2003-02-15

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948776T ATE231862T1 (de) 1998-09-23 1999-09-17 Tetrahydropyridoether

Country Status (31)

Country Link
US (4) US6436953B1 (et)
EP (1) EP1115725B1 (et)
JP (1) JP4145492B2 (et)
KR (1) KR100668400B1 (et)
CN (2) CN1155598C (et)
AT (1) ATE231862T1 (et)
AU (1) AU763463B2 (et)
BG (1) BG65195B1 (et)
BR (1) BR9914044A (et)
CA (1) CA2344251A1 (et)
CZ (1) CZ292335B6 (et)
DE (1) DE69905178T2 (et)
DK (1) DK1115725T3 (et)
EA (1) EA005377B1 (et)
EE (1) EE04677B1 (et)
ES (1) ES2191464T3 (et)
GE (1) GEP20032926B (et)
HK (1) HK1038360B (et)
HR (1) HRP20010224A2 (et)
HU (1) HUP0102990A3 (et)
ID (1) ID28896A (et)
IL (2) IL142063A0 (et)
NO (1) NO317304B1 (et)
NZ (1) NZ510610A (et)
PL (1) PL193616B1 (et)
PT (1) PT1115725E (et)
RS (1) RS50145B (et)
SI (1) SI1115725T1 (et)
SK (1) SK285165B6 (et)
TR (1) TR200100805T2 (et)
WO (1) WO2000017200A1 (et)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL193616B1 (pl) 1998-09-23 2007-02-28 Altana Pharma Ag Tetrahydropirydoetery
SI1173439T1 (en) 1999-04-17 2003-10-31 Altana Pharma Ag Haloalkoxy imidazonaphthyridines
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
ATE356131T1 (de) * 2000-03-29 2007-03-15 Altana Pharma Ag Tricyclische imidazopyridine
BR0109483A (pt) * 2000-03-29 2003-06-10 Altana Pharma Ag Pró-drogas de derivados de imidazopiridina
CA2426616A1 (en) * 2000-10-25 2002-05-02 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
IL157461A0 (en) * 2001-03-08 2004-03-28 Astrazeneca Ab Astrazeneca Ab Use of carboxamido imidazo [1,2] pyridine deivatives in the preparation of medicaments for treating or preventing gastric ulcer
US6927292B2 (en) 2001-08-02 2005-08-09 Altana Pharma Ag Tricyclic epoxides
KR20040023697A (ko) * 2001-08-03 2004-03-18 알타나 파마 아게 위장관계 장애의 치료를 위한 알킬 치환 이미다조피리딘
WO2003014120A1 (en) * 2001-08-03 2003-02-20 Altana Pharma Ag Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
JP2005519933A (ja) 2002-02-15 2005-07-07 アルタナ　ファルマ　アクチエンゲゼルシャフト 三環式ｎ−アシル化合物
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PL373287A1 (en) * 2002-05-07 2005-08-22 Altana Pharma Ag New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
CN100384842C (zh) 2002-11-19 2008-04-30 奥坦纳医药公司 8-取代的咪唑并吡啶类化合物
ATE405275T1 (de) 2002-12-12 2008-09-15 Nycomed Gmbh Kombinationsarzneimittel aus r,r-formoterol und ciclesonide
PL375933A1 (en) * 2002-12-20 2005-12-12 Altana Pharma Ag 8-trialkylsiloxy-2-methyl-9-phenyl-7-oxo-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridines
WO2004071391A2 (en) * 2003-02-17 2004-08-26 Altana Pharma Ag Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders
EP1606261B1 (en) 2003-03-10 2009-11-04 Nycomed GmbH Novel process for the preparation of roflumilast
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
WO2005021040A2 (en) * 2003-08-29 2005-03-10 Dynogen Pharmaceuticals, Inc. Compositions useful for treating gastrointestinal motility disorders
CA2538419C (en) 2003-09-16 2012-07-03 Altana Pharma Ag Use of ciclesonide for the treatment of respiratory diseases
CN1874772A (zh) * 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR047605A1 (es) * 2004-02-17 2006-01-25 Altana Pharma Ag Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos.
US8148529B2 (en) 2004-09-03 2012-04-03 Yuhan Corporation Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof
BRPI0514695A (pt) 2004-09-03 2008-06-17 Yuhan Corp derivados de pirrol[3, 2-b]piridina e processos para a preparação destes
KR100958830B1 (ko) 2004-09-03 2010-05-24 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
EP1861074B1 (en) * 2005-03-16 2013-04-24 Takeda GmbH Taste masked dosage form containing roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
JP5802898B2 (ja) 2009-07-09 2015-11-04 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
WO2013187727A1 (en) * 2012-06-15 2013-12-19 Bio-Pharm Solutions Co., Ltd. Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same
US20160235724A1 (en) 2013-10-08 2016-08-18 Katairo Gmbh Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
KR890701585A (ko) 1987-07-16 1989-12-21 헤르베르크 슈키·울리히 볼프 새로운 디아졸
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
NZ290819A (en) * 1994-07-28 1998-06-26 Byk Gulden Lomberg Chem Fab Acyl 8-benzyloxy- or 8-benzylaminoimidazopyridines
EA002402B1 (ru) * 1997-03-24 2002-04-25 Бык Гульден Ломберг Хемише Фабрик Гмбх Тетрагидропиридо-соединения
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
PL193616B1 (pl) * 1998-09-23 2007-02-28 Altana Pharma Ag Tetrahydropirydoetery

Also Published As

Publication number Publication date
IL142063A (en) 2007-10-31
PL346617A1 (en) 2002-02-25
CN1560055A (zh) 2005-01-05
HK1038360A1 (en) 2002-03-15
WO2000017200A1 (en) 2000-03-30
CN1319101A (zh) 2001-10-24
BG105270A (en) 2001-11-30
HUP0102990A3 (en) 2002-09-30
BG65195B1 (bg) 2007-06-29
CZ20011082A3 (cs) 2001-09-12
HRP20010224A2 (en) 2002-04-30
NZ510610A (en) 2003-07-25
DE69905178T2 (de) 2003-07-17
IL142063A0 (en) 2002-03-10
EE200100172A (et) 2002-06-17
DK1115725T3 (da) 2003-06-23
NO317304B1 (no) 2004-10-04
JP4145492B2 (ja) 2008-09-03
US7105676B2 (en) 2006-09-12
US6696460B2 (en) 2004-02-24
EP1115725A1 (en) 2001-07-18
SI1115725T1 (en) 2003-06-30
ID28896A (id) 2001-07-12
HUP0102990A2 (hu) 2002-01-28
BR9914044A (pt) 2001-12-04
EA200100315A1 (ru) 2001-10-22
AU6192099A (en) 2000-04-10
US6436953B1 (en) 2002-08-20
CZ292335B6 (cs) 2003-09-17
RS50145B (sr) 2009-03-25
PL193616B1 (pl) 2007-02-28
NO20011243D0 (no) 2001-03-12
YU21401A (sh) 2004-03-12
CA2344251A1 (en) 2000-03-30
CN100506821C (zh) 2009-07-01
JP2002526499A (ja) 2002-08-20
KR100668400B1 (ko) 2007-01-17
SK285165B6 (sk) 2006-07-07
DE69905178D1 (de) 2003-03-06
NO20011243L (no) 2001-03-12
HK1038360B (zh) 2003-05-16
US7393860B1 (en) 2008-07-01
PT1115725E (pt) 2003-06-30
AU763463B2 (en) 2003-07-24
GEP20032926B (en) 2003-03-25
CN1155598C (zh) 2004-06-30
EP1115725B1 (en) 2003-01-29
US20020169320A1 (en) 2002-11-14
KR20010075223A (ko) 2001-08-09
EE04677B1 (et) 2006-08-15
US20040162310A1 (en) 2004-08-19
TR200100805T2 (tr) 2001-08-21
ES2191464T3 (es) 2003-09-01
EA005377B1 (ru) 2005-02-24
SK3992001A3 (en) 2001-12-03

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