ATE226205T1 - Verbindungen - Google Patents
VerbindungenInfo
- Publication number
- ATE226205T1 ATE226205T1 AT98924705T AT98924705T ATE226205T1 AT E226205 T1 ATE226205 T1 AT E226205T1 AT 98924705 T AT98924705 T AT 98924705T AT 98924705 T AT98924705 T AT 98924705T AT E226205 T1 ATE226205 T1 AT E226205T1
- Authority
- AT
- Austria
- Prior art keywords
- links
- pyrimidinediones
- thieno
- processes
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9702001A SE9702001D0 (sv) | 1997-05-28 | 1997-05-28 | Novel compounds |
PCT/SE1998/000935 WO1998054190A1 (en) | 1997-05-28 | 1998-05-18 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE226205T1 true ATE226205T1 (de) | 2002-11-15 |
Family
ID=20407123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98924705T ATE226205T1 (de) | 1997-05-28 | 1998-05-18 | Verbindungen |
Country Status (28)
Country | Link |
---|---|
US (2) | US6180635B1 (de) |
EP (1) | EP0991653B1 (de) |
JP (1) | JP2002500666A (de) |
KR (1) | KR100561988B1 (de) |
CN (1) | CN1122037C (de) |
AT (1) | ATE226205T1 (de) |
AU (1) | AU723708B2 (de) |
BR (1) | BR9809481A (de) |
CA (1) | CA2289509C (de) |
CZ (1) | CZ297536B6 (de) |
DE (1) | DE69808765T2 (de) |
DK (1) | DK0991653T3 (de) |
EE (1) | EE04018B1 (de) |
ES (1) | ES2184270T3 (de) |
HU (1) | HU226627B1 (de) |
ID (1) | ID28432A (de) |
IL (2) | IL132763A0 (de) |
IS (1) | IS1983B (de) |
NO (1) | NO323752B1 (de) |
NZ (1) | NZ500853A (de) |
PL (1) | PL199567B1 (de) |
PT (1) | PT991653E (de) |
RU (1) | RU2225410C2 (de) |
SE (1) | SE9702001D0 (de) |
SK (1) | SK283589B6 (de) |
TR (1) | TR199902904T2 (de) |
UA (1) | UA61111C2 (de) |
WO (1) | WO1998054190A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9801399D0 (sv) | 1998-04-21 | 1998-04-21 | Astra Pharma Prod | Method and apparatus for filling containers |
GB9819382D0 (en) * | 1998-09-04 | 1998-10-28 | Cerebrus Ltd | Chemical compounds I |
GB9819384D0 (en) | 1998-09-04 | 1998-10-28 | Cerebrus Ltd | Chemical compounds II |
ATE272642T1 (de) * | 2000-05-04 | 2004-08-15 | Astrazeneca Ab | Thieno(2,3-d)pyrimidindione und ihre verwendung als pharmazeutische mittel |
GB2361917A (en) * | 2000-05-04 | 2001-11-07 | Astrazeneca Ab | Novel thieno[2,3-d]pyrimidinediones |
GB2363377B (en) * | 2000-06-14 | 2004-06-09 | Astrazeneca Ab | Novel thieno[2,3-d]pyrimidinediones and therapeutic uses thereof |
MXPA03004926A (es) * | 2001-02-14 | 2005-02-14 | Warner Lambert Co | Inhibidores de metaloproteinasas de matriz basados en pirimidinonas fusionadas. |
GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
BR0215212A (pt) * | 2001-12-21 | 2004-12-07 | Novo Nordisk As | Ativador de carboxamida ou sulfonamida de glicoquinase, composto, composição farmacêutica, e, uso de um composto |
KR101116627B1 (ko) * | 2002-06-27 | 2012-10-09 | 노보 노르디스크 에이/에스 | 치료제로서 아릴 카르보닐 유도체 |
US6890923B2 (en) * | 2002-12-16 | 2005-05-10 | Astrazeneca Ab | Compounds |
SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
WO2004065395A1 (en) * | 2003-01-17 | 2004-08-05 | Astrazeneca Ab | Thienopyridazinones and their use in modulation of autoimmune disease |
SE0300117D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel Compounds |
SE0300119D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
DK1723128T3 (da) | 2004-01-06 | 2013-02-18 | Novo Nordisk As | Heteroarylurinstoffer og deres anvendelse som glucokinaseaktivatorer |
JP2009500378A (ja) * | 2005-07-08 | 2009-01-08 | ノボ・ノルデイスク・エー/エス | グルコキナーゼ活性化剤としてのジシクロアルキルカルバモイル尿素 |
CA2614518A1 (en) * | 2005-07-08 | 2007-01-18 | Novo-Nordisk A/S | Dicycloalkyl urea glucokinase activators |
JP4960355B2 (ja) * | 2005-07-14 | 2012-06-27 | ノボ・ノルデイスク・エー/エス | ウレア型グルコキナーゼ活性化剤 |
JP2009528389A (ja) * | 2006-03-02 | 2009-08-06 | シーブイ・セラピューティクス・インコーポレイテッド | A2aアデノシン受容体拮抗剤 |
CN101186612B (zh) * | 2006-11-15 | 2012-10-03 | 天津和美生物技术有限公司 | 可抑制细胞释放肿瘤坏死因子的吡咯啉衍生物及其制备和应用 |
JP2010511628A (ja) * | 2006-12-01 | 2010-04-15 | ギリアード・パロ・アルト・インコーポレイテッド | A2aアデノシン受容体アンタゴニスト |
US8138185B2 (en) * | 2007-01-09 | 2012-03-20 | Novo Nordisk A/S | Urea glucokinase activators |
AU2008204530B2 (en) * | 2007-01-11 | 2013-08-01 | Vtv Therapeutics Llc | Urea glucokinase activators |
EP2008656A1 (de) | 2007-06-28 | 2008-12-31 | Bergen Teknologioverforing AS | Zusammensetzungen zur Behandlung von Hyperphenylalaninämie |
AU2010227225A1 (en) * | 2009-03-23 | 2011-09-15 | Glenmark Pharmaceuticals, S.A. | Furopyrimidinedione derivatives as TRPA1 modulators |
PL2776038T3 (pl) | 2011-11-11 | 2018-06-29 | Gilead Apollo, Llc | Inhibitory acc i ich zastosowania |
WO2014042176A1 (ja) * | 2012-09-14 | 2014-03-20 | キッセイ薬品工業株式会社 | 縮合複素環誘導体の製造方法およびその製造中間体 |
AU2014334040A1 (en) | 2013-10-07 | 2016-04-28 | Bayer Pharma Aktiengesellschaft | Cyclic thienouracil-carboxamides and use thereof |
UY36586A (es) | 2015-03-26 | 2016-10-31 | Bayer Pharma AG | Heterociclilmetiltienouracilos y uso de los mismos |
AR106472A1 (es) | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
PT3380480T (pt) | 2015-11-25 | 2023-03-14 | Gilead Apollo Llc | Inibidores de pirazol acc e seus usos |
CN108349994B (zh) | 2015-11-25 | 2021-06-22 | 吉利德阿波罗公司 | 三唑acc抑制剂及其用途 |
AU2016361414A1 (en) | 2015-11-25 | 2018-05-24 | Gilead Apollo, Llc | Ester ACC inhibitors and uses thereof |
MX2018006285A (es) | 2015-11-25 | 2018-09-07 | Gilead Apollo Llc | Composiciones fungicidas que contienen derivados de 2,4-dioxido-1,4-dihidrotieno[2,3-d] pirimidina. |
TW202400605A (zh) | 2016-03-02 | 2024-01-01 | 美商基利阿波羅有限責任公司 | 噻吩并嘧啶二酮acc抑制劑之固體型式及其製造方法 |
WO2018041771A1 (de) | 2016-09-02 | 2018-03-08 | Bayer Pharma Aktiengesellschaft | (1-methylcyclopropyl)methyl-substituierte thienouracile und ihre verwendung |
US20200016159A1 (en) | 2016-09-23 | 2020-01-16 | Bayer Aktiengesellschaft | N3-cyclically substituted thienouracils and use thereof |
AU2018243719B2 (en) | 2017-03-28 | 2021-01-21 | Gilead Sciences, Inc. | Therapeutic combinations for treating liver diseases |
MX2020008905A (es) | 2018-06-12 | 2020-12-03 | Vtv Therapeutics Llc | Usos terapeuticos de activadores de glucoquinasa en combinacion con insulina o analogos de insulinas. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0335979A4 (en) * | 1987-09-16 | 1992-02-26 | Taiho Pharmaceutical Company, Limited | Thienopyrimidine derivatives |
TW276256B (de) | 1993-08-26 | 1996-05-21 | Takeda Pharm Industry Co Ltd | |
FR2750862B1 (fr) * | 1996-07-12 | 1998-10-16 | Dupin Jean Pierre | Utilisation d'heterocycles diazotes fusionnes avec un systeme aromatique ou heteroaromatique pour le traitement des maladies thrombo-emboliques |
-
1997
- 1997-05-28 SE SE9702001A patent/SE9702001D0/xx unknown
-
1998
- 1998-05-18 CA CA002289509A patent/CA2289509C/en not_active Expired - Fee Related
- 1998-05-18 SK SK1513-99A patent/SK283589B6/sk not_active IP Right Cessation
- 1998-05-18 DE DE69808765T patent/DE69808765T2/de not_active Expired - Fee Related
- 1998-05-18 HU HU0003355A patent/HU226627B1/hu not_active IP Right Cessation
- 1998-05-18 CN CN98807378A patent/CN1122037C/zh not_active Expired - Fee Related
- 1998-05-18 RU RU99128111/04A patent/RU2225410C2/ru not_active IP Right Cessation
- 1998-05-18 KR KR1019997011086A patent/KR100561988B1/ko not_active IP Right Cessation
- 1998-05-18 ID IDW991450A patent/ID28432A/id unknown
- 1998-05-18 JP JP50056599A patent/JP2002500666A/ja not_active Ceased
- 1998-05-18 CZ CZ0420199A patent/CZ297536B6/cs not_active IP Right Cessation
- 1998-05-18 EP EP98924705A patent/EP0991653B1/de not_active Expired - Lifetime
- 1998-05-18 TR TR1999/02904T patent/TR199902904T2/xx unknown
- 1998-05-18 US US09/117,426 patent/US6180635B1/en not_active Expired - Fee Related
- 1998-05-18 IL IL13276398A patent/IL132763A0/xx active IP Right Grant
- 1998-05-18 BR BR9809481-5A patent/BR9809481A/pt not_active Application Discontinuation
- 1998-05-18 AU AU76808/98A patent/AU723708B2/en not_active Ceased
- 1998-05-18 NZ NZ500853A patent/NZ500853A/en unknown
- 1998-05-18 DK DK98924705T patent/DK0991653T3/da active
- 1998-05-18 ES ES98924705T patent/ES2184270T3/es not_active Expired - Lifetime
- 1998-05-18 PT PT98924705T patent/PT991653E/pt unknown
- 1998-05-18 PL PL337126A patent/PL199567B1/pl not_active IP Right Cessation
- 1998-05-18 UA UA99127140A patent/UA61111C2/uk unknown
- 1998-05-18 WO PCT/SE1998/000935 patent/WO1998054190A1/en active IP Right Grant
- 1998-05-18 AT AT98924705T patent/ATE226205T1/de not_active IP Right Cessation
- 1998-05-18 EE EEP199900539A patent/EE04018B1/xx not_active IP Right Cessation
-
1999
- 1999-11-04 IL IL132763A patent/IL132763A/en not_active IP Right Cessation
- 1999-11-23 IS IS5264A patent/IS1983B/is unknown
- 1999-11-26 NO NO19995810A patent/NO323752B1/no unknown
-
2000
- 2000-10-23 US US09/693,896 patent/US6342502B1/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE226205T1 (de) | Verbindungen | |
DE69807741D1 (de) | Neuartige verbindungen | |
SE9701398D0 (sv) | Novel compounds | |
IL114003A (en) | 1,4,6-Trisubstituted 1H-pyrrolo[2,3-b]pyridine and 1-H-pyrazolo[3,4-b] pyridine derivatives and pharmaceutical compositions containing them and some intermediates for their preparation | |
ZA965752B (en) | Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents. | |
DE69808130D1 (de) | Adamantan-derivate | |
DE69905170D1 (en) | Thiazolopyrimidinderivate | |
IS5082A (is) | Pýrróló[3,4-D]pýrimídínon-afleiður og notkun þeirra sem lyfja | |
MX9601994A (es) | Profarmacos de derivados de paclitaxel. | |
ATE240303T1 (de) | 1,2,4-triazol-3-thion verbindungen | |
PH30665A (en) | Aminosulfonyl urea acat inhibitors | |
MX9704034A (es) | Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso. | |
AP2001002369A0 (en) | Pharmaceutical complex. | |
MY103593A (en) | Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation | |
AU2001252825A1 (en) | Thieno(2,3-d)pyrimidinediones and their use as pharmaceuticals | |
TR199801251T2 (xx) | Eritrosit olu�umunu te�vik i�in thieno (2,3-b) pyrazolo (3,4-D) pyridin-3-on'lar. | |
MX9802809A (es) | Ureasa para el tratamiento de infecciones de helicobacter pylori. | |
MY113450A (en) | Anellated b-carbolines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0991653 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |