ATE225847T1 - Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen - Google Patents

Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Info

Publication number
ATE225847T1
ATE225847T1 AT93908270T AT93908270T ATE225847T1 AT E225847 T1 ATE225847 T1 AT E225847T1 AT 93908270 T AT93908270 T AT 93908270T AT 93908270 T AT93908270 T AT 93908270T AT E225847 T1 ATE225847 T1 AT E225847T1
Authority
AT
Austria
Prior art keywords
cells
compositions
maintaining
methods
devices
Prior art date
Application number
AT93908270T
Other languages
English (en)
Inventor
Bernhard O Palsson
Stephen G Emerson
Richard M Schwartz
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of ATE225847T1 publication Critical patent/ATE225847T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT93908270T 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen ATE225847T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84596992A 1992-03-04 1992-03-04
PCT/US1993/001803 WO1993018132A1 (en) 1992-03-04 1993-03-04 Methods, compositions and devices for maintaining and growing human stem and/or hematopoietic cells

Publications (1)

Publication Number Publication Date
ATE225847T1 true ATE225847T1 (de) 2002-10-15

Family

ID=25296563

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93908270T ATE225847T1 (de) 1992-03-04 1993-03-04 Verfahren,zusammensetzungen und vorrichtungen zur erhaltung und zur züchtung menschlicher stammzellen und/oder hämatopoetischer zellen

Country Status (8)

Country Link
EP (1) EP0629236B1 (de)
JP (1) JPH07504570A (de)
KR (1) KR100271284B1 (de)
AT (1) ATE225847T1 (de)
AU (1) AU685743B2 (de)
CA (1) CA2131385C (de)
DE (1) DE69332374T2 (de)
WO (1) WO1993018132A1 (de)

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US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
JPH09501324A (ja) * 1994-03-11 1997-02-10 バクスター、インターナショナル、インコーポレイテッド 細胞保持用の溝を備えた貫流バイオリアクター
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
AU5931896A (en) * 1995-06-07 1996-12-30 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
US5843766A (en) * 1995-06-07 1998-12-01 Advanced Tissue Sciences, Inc. Apparatus for the growth and packaging of three dimensional tissue cultures
US5688687A (en) * 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
US5763267A (en) * 1996-04-16 1998-06-09 Advanced Tissue Sciences Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
WO1998050522A1 (en) * 1997-05-07 1998-11-12 Baxter International Inc. Method and apparatus for high volume production of viral particles
FR2771421B1 (fr) * 1997-11-27 2001-05-04 Bertin & Cie Dispositif d'amplification de cellules hematopoietiques et ses applications
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
EP1408746B1 (de) * 2000-10-06 2015-07-01 Dancu, Michael B. System und verfahren zur simulation der hämodynamik
DE10128810B4 (de) * 2001-06-18 2013-11-07 Pan-Biotech Gmbh Einrichtung zur Kultivierung von Zellen, insbesondere menschlicher oder tierischer Zellen
AU2003218572B2 (en) * 2002-04-08 2009-08-20 Octane Biotech, Inc. Automated tissue engineering system
DE10223536A1 (de) * 2002-05-27 2003-12-18 J Hinrich Peters Verfahren zur Trennung nicht-adhärenter Zellen von adhärenten Zellen
EP1539922B1 (de) 2002-09-16 2007-10-24 Pan-Biotech GmbH Verfahren zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
CN1993460A (zh) * 2004-07-12 2007-07-04 索林集团意大利有限公司 用于培养人细胞的装置和方法
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
WO2008028241A1 (en) * 2006-09-06 2008-03-13 The University Of Queensland Microbioreactor
JP5666131B2 (ja) * 2008-02-22 2015-02-12 コバレントマテリアル株式会社 細胞培養モジュール
MX353489B (es) * 2009-07-02 2018-01-16 Anthrogenesis Corp Metodo para producir eritrocitos sin celulas alimentadoras.
GB0914195D0 (en) * 2009-08-13 2009-09-16 Plasticell Ltd Vessel for culturing cells
AU2012271341B2 (en) 2011-06-15 2017-07-13 The Charles Stark Draper Laboratory, Inc. Systems, methods, and devices relating to a biomimetic cellularized nephron unit
WO2012174445A1 (en) * 2011-06-15 2012-12-20 The Charles Stark Draper Laboratory, Inc. Device and method for culturing cells in a biomimetic environment
SG11201404608WA (en) 2012-02-13 2014-09-26 Gamida Cell Ltd Mesenchymal stem cells conditioned medium and methods of generating and using the same
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
JP5828823B2 (ja) * 2012-09-28 2015-12-09 クアーズテック株式会社 細胞培養モジュール及び細胞培養方法
US10866169B2 (en) 2012-10-17 2020-12-15 Konica Minolta, Inc. Method for recovering rare cells and method for detecting rare cells
JP2014124097A (ja) * 2012-12-25 2014-07-07 Hitachi High-Technologies Corp 核酸分析用カートリッジ及び核酸分析装置
US20170158999A1 (en) * 2015-12-03 2017-06-08 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Modular bioreactor for culture of biopaper based tissues
JP7116061B2 (ja) * 2016-08-21 2022-08-09 アドヴァ バイオテクノロジー リミテッド バイオリアクタおよびその使用法
DE102018000561B4 (de) 2018-01-24 2019-11-07 Zellwerk Gmbh Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE202018000370U1 (de) 2018-01-24 2018-04-12 Zellwerk Gmbh Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE202018004857U1 (de) 2018-10-20 2019-01-14 Zellwerk Gmbh Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen
US20230242864A1 (en) * 2022-01-31 2023-08-03 Sciperio, Inc In-time storage of manufactured cells for medical cellular therapy grown and differentiated in bioreactors

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Publication number Priority date Publication date Assignee Title
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
ZA839242B (en) * 1982-12-15 1984-09-26 Bio Response Inc A method and system for culturing and treating substances disposed in a flowing culture fluid
US5135853A (en) * 1983-07-22 1992-08-04 Rensselaer Polytechnic Institute Three compartment bioreactor and method of use
DE3409501A1 (de) * 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen
US4894342A (en) * 1986-05-12 1990-01-16 C. D. Medical, Inc. Bioreactor system
US4861483A (en) * 1986-07-07 1989-08-29 Cornell Research Foundation, Inc. Apparatus and process to eliminate diffusional limitations in a membrane biological reactor by pressure cycling
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
ES2097149T3 (es) * 1989-06-15 1997-04-01 Univ Michigan Procedimientos, composiciones y dispositivos para desarrollar celulas.
DE69214391T2 (de) * 1991-06-19 1997-05-15 Endotronics Inc Zellkultur Apparat
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen

Also Published As

Publication number Publication date
DE69332374D1 (de) 2002-11-14
JPH07504570A (ja) 1995-05-25
EP0629236A1 (de) 1994-12-21
CA2131385C (en) 2008-07-15
EP0629236A4 (de) 1997-06-04
AU685743B2 (en) 1998-01-29
KR100271284B1 (ko) 2000-11-01
EP0629236B1 (de) 2002-10-09
CA2131385A1 (en) 1993-09-16
DE69332374T2 (de) 2003-06-12
AU3914893A (en) 1993-10-05
WO1993018132A1 (en) 1993-09-16

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