ATE220401T1 - Chinolonderivate und verfahren zu deren herstellung - Google Patents

Chinolonderivate und verfahren zu deren herstellung

Info

Publication number
ATE220401T1
ATE220401T1 AT94904771T AT94904771T ATE220401T1 AT E220401 T1 ATE220401 T1 AT E220401T1 AT 94904771 T AT94904771 T AT 94904771T AT 94904771 T AT94904771 T AT 94904771T AT E220401 T1 ATE220401 T1 AT E220401T1
Authority
AT
Austria
Prior art keywords
pct
chinolone
derivatives
production
sec
Prior art date
Application number
AT94904771T
Other languages
English (en)
Inventor
Wan Joo Kim
Tae Ho Park
Bong Jin Kim
Moon Hwan Kim
Neil Pearson
Original Assignee
Korea Res Inst Chem Tech
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Res Inst Chem Tech, Smithkline Beecham Plc filed Critical Korea Res Inst Chem Tech
Application granted granted Critical
Publication of ATE220401T1 publication Critical patent/ATE220401T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT94904771T 1993-01-18 1994-01-18 Chinolonderivate und verfahren zu deren herstellung ATE220401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019930000543A KR0148277B1 (ko) 1993-01-18 1993-01-18 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
PCT/KR1994/000005 WO1994015938A1 (en) 1993-01-18 1994-01-18 Novel quinolone derivatives and processes for preparing the same

Publications (1)

Publication Number Publication Date
ATE220401T1 true ATE220401T1 (de) 2002-07-15

Family

ID=19349719

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94904771T ATE220401T1 (de) 1993-01-18 1994-01-18 Chinolonderivate und verfahren zu deren herstellung

Country Status (8)

Country Link
US (1) US5770597A (de)
EP (1) EP0690862B1 (de)
JP (1) JPH08505385A (de)
KR (1) KR0148277B1 (de)
AT (1) ATE220401T1 (de)
AU (1) AU5866594A (de)
DE (1) DE69430950T2 (de)
WO (1) WO1994015938A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703244A (en) * 1996-11-21 1997-12-30 Abbott Laboratories Process for preparation of chiral 3-amino-pyrrolidine and analogous bicyclic compounds
DE19735198A1 (de) * 1997-08-14 1999-02-18 Bayer Ag Verfahren zur Racematspaltung von cis- und trans-Pyrrolopiperidin
AR013493A1 (es) * 1997-09-15 2000-12-27 Procter & Gamble COMPUESTO DE QUINOLONA, SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO Y COMPOSICIoN FARMACEUTICA QUE LO COMPRENDE
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US6197974B1 (en) 1998-10-26 2001-03-06 Abbott Laboratories Enantioselective synthesis of 3-aminopyrrolidines
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6777420B2 (en) 2001-06-15 2004-08-17 Microbiotix, Inc. Heterocyclic antibacterial compounds
ATE366734T1 (de) 2003-09-04 2007-08-15 Wockhardt Ltd Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat
MY145148A (en) * 2004-08-13 2011-12-30 Schering Plough Ltd Pharmaceutical formulation comprising an antibiotic, a triazole and a carticosteroid
HRP20110558T1 (hr) * 2006-03-28 2011-09-30 Warner Chilcott Company Malatne soli i polimorfi od (3s, 5s)-7-[3-amino-5-metil-piperidinil]-1-ciklopropil-1, 4-dihidro-8-metoksi-4-okso-3-kinolinkarboksilne kiseline
WO2007110835A2 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
JP4876165B2 (ja) * 2006-03-28 2012-02-15 ザ プロクター アンド ギャンブル カンパニー キノロン中間体を調製するための水素化物還元法
US7692015B2 (en) * 2007-01-05 2010-04-06 Zheqing Wang Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
NZ610978A (en) * 2009-05-15 2014-11-28 Redx Pharma Ltd Redox drug derivatives
KR101279822B1 (ko) * 2011-08-02 2013-06-28 한국해양과학기술원 브로모페놀계 화합물, 이것의 제조방법 및 이것을 포함하는 조성물
CN102964346B (zh) * 2011-09-01 2015-04-22 中国中化股份有限公司 一种制备(S,S)-八氢-6H-吡咯并[3,4-b]吡啶的方法
CN103044418B (zh) * 2011-10-14 2015-02-04 上海朴颐化学科技有限公司 (s,s)-2,8-二氮杂双环[4,3,0]壬烷的不对称合成方法、相关原料及制备方法
CN104277036B (zh) * 2013-07-02 2016-12-28 上海朴颐化学科技有限公司 一种(4aS,7aS)‑八氢‑1H‑吡咯并[3,4‑b]吡啶的纯化方法
CN106188047B (zh) * 2016-07-08 2019-07-05 上海沃凯生物技术有限公司 一种制备6-(1-苯基-乙基)-吡咯并[3,4-b]吡啶-5,7-二酮的方法
CN106083846B (zh) * 2016-07-08 2019-07-05 上海沃凯生物技术有限公司 一种6-(1-苯基-乙基)-吡咯并[3,4-b]吡啶-5,7-二酮的合成方法
RU2713932C1 (ru) * 2019-10-31 2020-02-11 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Соединения фторхинолонового ряда на основе производных пиридоксина, обладающие антибактериальными свойствами

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60228479A (ja) * 1984-04-26 1985-11-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
DE3632222A1 (de) * 1986-09-23 1988-04-07 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren
US4965273A (en) * 1986-10-08 1990-10-23 Bristol-Myers Company Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents
US4954507A (en) * 1986-10-08 1990-09-04 Bristol-Myers Company 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents
NZ222047A (en) * 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
CA2012681A1 (en) * 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
DE4032560A1 (de) * 1990-10-13 1992-04-16 Bayer Ag 7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate
TW209865B (de) * 1992-01-10 1993-07-21 Bayer Ag
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same

Also Published As

Publication number Publication date
EP0690862B1 (de) 2002-07-10
KR0148277B1 (ko) 1998-11-02
AU5866594A (en) 1994-08-15
DE69430950T2 (de) 2002-11-14
WO1994015938A1 (en) 1994-07-21
KR940018383A (ko) 1994-08-16
EP0690862A1 (de) 1996-01-10
JPH08505385A (ja) 1996-06-11
US5770597A (en) 1998-06-23
DE69430950D1 (de) 2002-08-14

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties