US5831002A
(en)
*
|
1992-05-20 |
1998-11-03 |
Basf Aktiengesellschaft |
Antitumor peptides
|
US5530097A
(en)
*
|
1994-08-01 |
1996-06-25 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory peptide amides
|
US5807984A
(en)
*
|
1995-11-09 |
1998-09-15 |
Basf Aktienegesellschaft |
Oligopeptides, the preparation and use thereof
|
US20010009901A1
(en)
*
|
1996-12-11 |
2001-07-26 |
Basf Aktiengesellschaft Germany |
Antineoplastic peptides
|
US5939527A
(en)
*
|
1996-07-30 |
1999-08-17 |
Basf Aktiengesellschaft |
Tetrapeptides as antitumor agents
|
US5741892A
(en)
*
|
1996-07-30 |
1998-04-21 |
Basf Aktiengesellschaft |
Pentapeptides as antitumor agents
|
CA2282504A1
(en)
|
1997-02-25 |
1998-08-27 |
Jun-Ping Xu |
Isolation and structural elucidation of the cytostatic linear and cyclo-depsipeptides dolastatin 16, dolastatin 17, and dolastatin 18
|
US5965537A
(en)
*
|
1997-03-10 |
1999-10-12 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
|
US6103698A
(en)
|
1997-03-13 |
2000-08-15 |
Basf Aktiengesellschaft |
Dolastatin-15 derivatives in combination with taxanes
|
US6143721A
(en)
|
1997-07-18 |
2000-11-07 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives
|
US6015790A
(en)
*
|
1997-10-06 |
2000-01-18 |
Basf Aktiengesellschaft |
Methods and compositions for treating rheumatoid arthritis
|
FR2774989B1
(fr)
*
|
1998-02-18 |
2000-03-17 |
Adir |
Nouveaux cytotoxiques derives de l'oestradiol
|
US5985837A
(en)
*
|
1998-07-08 |
1999-11-16 |
Basf Aktiengesellschaft |
Dolastatin 15 derivatives
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
EP2289549A3
(de)
|
1999-10-01 |
2011-06-15 |
Immunogen, Inc. |
Immunokonjugate für Krebsbehandlung
|
US6884869B2
(en)
*
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
US7256257B2
(en)
|
2001-04-30 |
2007-08-14 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
SI1545613T1
(sl)
|
2002-07-31 |
2011-11-30 |
Seattle Genetics Inc |
Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni
|
AU2004213053C1
(en)
|
2003-02-20 |
2009-07-16 |
Seagen Inc. |
Anti-CD70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
|
EP2478912B1
(de)
*
|
2003-11-06 |
2016-08-31 |
Seattle Genetics, Inc. |
Konjugate von Auristatin mit gegen HER2- oder CD22-gerichtete Antikörper und deren therapeutische Verwendung
|
CA2589374C
(en)
|
2004-11-30 |
2016-05-03 |
Curagen Corporation |
Antibodies directed to gpnmb and uses thereof
|
US20060149603A1
(en)
*
|
2005-01-04 |
2006-07-06 |
Barbara Patterson |
Method and system for determining healthcare eligibility
|
AU2006236225C1
(en)
|
2005-04-19 |
2013-05-02 |
Seagen Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
EP1883627B1
(de)
|
2005-05-18 |
2018-04-18 |
Pharmascience Inc. |
An die bir-domäne bindende verbindungen
|
US8318717B2
(en)
|
2005-05-25 |
2012-11-27 |
2Curex |
Compounds modifying apoptosis
|
EP1888619B1
(de)
*
|
2005-05-25 |
2013-04-17 |
2cureX ApS |
Apoptosemodifizierende Verbindungen
|
WO2007008848A2
(en)
*
|
2005-07-07 |
2007-01-18 |
Seattle Genetics, Inc. |
Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
|
ES2585357T3
(es)
|
2005-07-07 |
2016-10-05 |
Seattle Genetics, Inc. |
Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C
|
EP4026840A1
(de)
|
2005-07-18 |
2022-07-13 |
Seagen Inc. |
Beta-glukuronid-linker-wirkstoffkonjugate
|
JP5419685B2
(ja)
|
2006-05-16 |
2014-02-19 |
ファーマサイエンス・インコーポレイテッド |
Iapbirドメイン結合タンパク質
|
WO2007143600A2
(en)
*
|
2006-06-05 |
2007-12-13 |
Incyte Corporation |
Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases
|
EP2609932B1
(de)
|
2006-12-01 |
2022-02-02 |
Seagen Inc. |
Veränderliche target-bindemittel und verwendungen davon
|
ES2579323T3
(es)
|
2007-07-16 |
2016-08-09 |
Genentech, Inc. |
Anticuerpos anti-CD79B e inmunoconjugados y métodos de uso
|
CL2008002083A1
(es)
|
2007-07-16 |
2008-11-21 |
Genentech Inc |
Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico
|
EP2197489B2
(de)
|
2007-10-04 |
2020-04-01 |
ZymoGenetics, Inc. |
B7-familienmitglied zb7h6 und verwandte zusammensetzungen und verfahren
|
JP5580205B2
(ja)
|
2007-11-19 |
2014-08-27 |
セレラ コーポレーション |
肺癌マーカーとその使用
|
ES2613963T3
(es)
|
2008-01-18 |
2017-05-29 |
Medimmune, Llc |
Anticuerpos manipulados con cisteína para conjugación específica de sitio
|
PE20091318A1
(es)
|
2008-01-31 |
2009-09-16 |
Genentech Inc |
Anticuerpos anti-cd79b e inmunoconjugados y metodos de uso de los mismos
|
WO2009135181A2
(en)
|
2008-05-02 |
2009-11-05 |
Seattle Genetics, Inc. |
Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
|
CA2766405A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
Engineered fc regions for site-specific conjugation
|
MX366890B
(es)
|
2009-10-23 |
2019-07-30 |
Millennium Pharm Inc |
Moléculas de anticuerpo anti - gcc y composiciones y métodos relacionados.
|
PL2510011T3
(pl)
|
2009-12-09 |
2015-02-27 |
Inst Nat Sante Rech Med |
Przeciwciała monoklonalne, które wiążą B7H6 i ich zastosowania
|
AU2011213609B2
(en)
|
2010-02-08 |
2016-11-03 |
Agensys, Inc. |
Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
|
NZ602368A
(en)
|
2010-02-12 |
2014-10-31 |
Pharmascience Inc |
Iap bir domain binding compounds
|
CA2794332C
(en)
|
2010-03-31 |
2019-05-14 |
Boehringer Ingelheim International Gmbh |
Anti-cd40 antibodies
|
PL3409287T3
(pl)
|
2010-09-29 |
2021-09-27 |
Agensys, Inc. |
Koniugaty leków i przeciwciał (adc), które wiążą białka 191p4d12
|
AU2011316917B2
(en)
|
2010-10-22 |
2016-02-25 |
Seagen Inc. |
Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway
|
EP2690955A4
(de)
|
2011-03-30 |
2014-10-15 |
Univ Arizona |
Auristatin-tyramin-phosphat-salze und auristatin-aminochinolin-derivate und prodrugs davon
|
AU2012257418B2
(en)
|
2011-05-16 |
2017-08-03 |
Tagworks Pharmaceuticals B.V. |
Bio-orthogonal drug activation
|
JP2014516960A
(ja)
|
2011-05-19 |
2014-07-17 |
インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) |
抗ヒトher3抗体及びその使用
|
BR112013031819B1
(pt)
|
2011-06-10 |
2022-05-03 |
Mersana Therapeutics, Inc |
Suporte polimérico, composição farmacêutica, composto, e, uso do suporte
|
CA2839508A1
(en)
|
2011-06-22 |
2012-12-27 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Anti-axl antibodies and uses thereof
|
CN103747803B
(zh)
|
2011-06-22 |
2016-10-12 |
国家医疗保健研究所 |
抗axl抗体及其用途
|
MX352738B
(es)
|
2011-11-17 |
2017-12-06 |
Pfizer |
Peptidos citotoxicos y conjugados de anticuerpo-farmaco de los mismos.
|
CA3111357A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
WO2013109994A1
(en)
|
2012-01-20 |
2013-07-25 |
Sea Lane Biotechnologies, Llc |
Surrobody cojugates
|
US9156915B2
(en)
|
2012-04-26 |
2015-10-13 |
Thomas Jefferson University |
Anti-GCC antibody molecules
|
US9522940B2
(en)
|
2012-05-23 |
2016-12-20 |
Pieris Pharmaceuticals Gmbh |
Lipocalin muteins with binding-affinity for glypican-3 (GPC-3) and use of lipocalin muteins for target-specific delivery to cells expressing GPC-3
|
PL2859017T3
(pl)
|
2012-06-08 |
2019-07-31 |
Sutro Biopharma, Inc. |
Przeciwciała zawierające swoiste dla miejsca, niewystępujące naturalnie reszty aminokwasowe, sposoby ich wytwarzania i sposoby ich zastosowania
|
EP3488870B1
(de)
|
2012-06-19 |
2024-03-20 |
Ambrx, Inc. |
Anti-cd70-antikörper-arzneimittelkonjugate
|
WO2014004639A1
(en)
|
2012-06-26 |
2014-01-03 |
Sutro Biopharma, Inc. |
Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
PH12021551473A1
(en)
|
2012-08-23 |
2022-04-25 |
Agensys Inc |
Antibody drug conjugates (adc) that bind to 158p1d7 proteins
|
KR102182800B1
(ko)
|
2012-08-31 |
2020-11-25 |
서트로 바이오파마, 인크. |
아지도 기를 포함하는 변형된 아미노산
|
EP2922574B1
(de)
|
2012-11-22 |
2023-05-17 |
Tagworks Pharmaceuticals B.V. |
Chemisch spaltbare gruppe
|
AU2012395148B2
(en)
|
2012-11-24 |
2016-10-27 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
EP2928504B1
(de)
|
2012-12-10 |
2019-02-20 |
Mersana Therapeutics, Inc. |
Protein-polymer-wirkstoffkonjugate
|
US9872918B2
(en)
|
2012-12-12 |
2018-01-23 |
Mersana Therapeutics, Inc. |
Hydroxyl-polymer-drug-protein conjugates
|
HUE044071T2
(hu)
|
2013-03-15 |
2019-09-30 |
Abbvie Deutschland |
Anti-EGFR ellenanyag és farmakon konjugátumát tartalmazó készítmények
|
KR20150132864A
(ko)
|
2013-03-15 |
2015-11-26 |
애브비 인코포레이티드 |
항체 약물 접합체(adc) 정제
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
EP3027220A1
(de)
|
2013-08-01 |
2016-06-08 |
Agensys, Inc. |
An cd37-proteine bindende antikörper-wirkstoffkonjugate (adc)
|
JP6282745B2
(ja)
|
2013-09-12 |
2018-02-21 |
ハロザイム インコーポレイテッド |
修飾抗上皮成長因子受容体抗体およびその使用法
|
RU2016117810A
(ru)
|
2013-10-11 |
2017-11-17 |
Асана Биосайенсис, Ллк |
Конъюгаты белок-полимер-лекарственное средство
|
EA032231B1
(ru)
|
2013-10-11 |
2019-04-30 |
Мерсана Терапьютикс, Инк. |
Конъюгаты белок-полимер-лекарственное средство
|
EP3620470B1
(de)
|
2013-10-11 |
2023-07-26 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Tem-8-antikörper und deren verwendung
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
WO2015057461A2
(en)
|
2013-10-18 |
2015-04-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that specifically bind ataxia telangiectasia-mutated and rad3-related kinase phosphorylated at position 1989 and their use
|
US20160280798A1
(en)
|
2013-11-06 |
2016-09-29 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Service |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
EP3066124B1
(de)
|
2013-11-07 |
2021-01-06 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Gegen her3, neuregulin allosterische antikörpern
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
EP3094350B1
(de)
|
2014-01-15 |
2020-03-04 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Auf knorpel gerichtete wirkstoffe und deren verwendung
|
CN106414465B
(zh)
|
2014-02-28 |
2021-11-16 |
杭州多禧生物科技有限公司 |
带电荷链接体及其在共轭反应上的应用
|
RU2020124944A
(ru)
|
2014-03-21 |
2020-08-27 |
Эббви Инк. |
Антитела против egfr и конъюгаты антитело-лекарственное средство
|
FR3020063A1
(fr)
|
2014-04-16 |
2015-10-23 |
Gamamabs Pharma |
Anticorps humain anti-her4
|
WO2015183978A1
(en)
*
|
2014-05-28 |
2015-12-03 |
Agensys, Inc. |
Derivatives of dolaproine-dolaisoleuine peptides
|
EP3473271B1
(de)
|
2014-07-31 |
2022-07-20 |
The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services |
Humane monoklonale antikörper gegen epha4 und deren verwendung
|
BR112017023576A2
(pt)
|
2014-09-23 |
2023-10-03 |
Genentech Inc |
Método para tratar uma disfunção proliferativa de células b
|
WO2016130969A1
(en)
|
2015-02-13 |
2016-08-18 |
George Robert Pettit |
Silstatin compounds
|
US10301377B2
(en)
|
2015-02-24 |
2019-05-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
JP6764873B2
(ja)
|
2015-03-09 |
2020-10-07 |
アジェンシス,インコーポレイテッド |
Flt3タンパク質に結合する抗体薬物複合体(adc)
|
EP3091033A1
(de)
|
2015-05-06 |
2016-11-09 |
Gamamabs Pharma |
Anti-human-her3-antikörper und verwendungen davon
|
WO2016180948A1
(en)
|
2015-05-12 |
2016-11-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and kits for labeling, detection and isolation of foxp3+ regulatory t cells, isolated population of foxp3+ regulatory t cells thus obtained and uses thereof
|
WO2016188911A1
(en)
|
2015-05-22 |
2016-12-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies fragments inhibiting both the cath-d catalytic activity and its binding to the lrp1 receptor
|
US20180134788A1
(en)
|
2015-05-26 |
2018-05-17 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and Pharmaceutical Compositions (NTSR1 Inhibitors) for the Treatment of Hepatocellular Carcinomas
|
WO2016189118A1
(en)
|
2015-05-28 |
2016-12-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of prognosis and treatment of patients suffering from acute myeloid leukemia
|
ES2961346T3
(es)
|
2015-06-12 |
2024-03-11 |
Lentigen Tech Inc |
Procedimiento para tratar cáncer con células T modificadas genéticamente
|
WO2015151081A2
(en)
|
2015-07-12 |
2015-10-08 |
Suzhou M-Conj Biotech Co., Ltd |
Bridge linkers for conjugation of a cell-binding molecule
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
AU2016335750B2
(en)
|
2015-10-07 |
2023-05-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
IL-7R-alpha specific antibodies for treating acute lymphoblastic leukemia
|
EP3660044A1
(de)
|
2015-10-09 |
2020-06-03 |
Miltenyi Biotec Technology, Inc. |
Chimäre antigen-rezeptoren und methoden zur verwendung davon
|
WO2017064034A1
(en)
|
2015-10-12 |
2017-04-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
An agent capable of depleting cd8 t cells for the treatment of myocardial infarction or acute myocardial infarction
|
CN106674327A
(zh)
*
|
2015-11-10 |
2017-05-17 |
复旦大学 |
一种Dolastatin 10衍生物、其制备方法及应用
|
CN109069664B
(zh)
|
2016-01-27 |
2022-05-13 |
苏特罗生物制药公司 |
抗cd74抗体偶联物,包含抗cd74抗体偶联物的组合物以及抗cd74抗体偶联物的使用方法
|
US11191821B2
(en)
|
2016-02-27 |
2021-12-07 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Peptide vaccine formulations and use thereof for inducing an immune response
|
TW201740979A
(zh)
|
2016-02-29 |
2017-12-01 |
瑪德瑞高製藥公司 |
熱休克蛋白(hsp)90抑制劑藥物共軛物
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
UA125510C2
(uk)
|
2016-03-25 |
2022-04-13 |
Сіджен Інк. |
Спосіб отримання пегильованої сполуки лікарський препарат-лінкер, де лікарським препаратом є ауристатин, та її проміжних сполук
|
MX2018015285A
(es)
|
2016-06-08 |
2019-09-18 |
Abbvie Inc |
Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco.
|
AU2017279539A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-B7-H3 antibodies and antibody drug conjugates
|
UA124198C2
(uk)
|
2016-06-08 |
2021-08-04 |
Еббві Інк. |
Кон'югат антитіла до в7-н3 та лікарського засобу
|
US20200147235A1
(en)
|
2016-06-08 |
2020-05-14 |
Abbvie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
AU2017277914A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-CD98 antibodies and antibody drug conjugates
|
US11617799B2
(en)
|
2016-06-27 |
2023-04-04 |
Tagworks Pharmaceuticals B.V. |
Cleavable tetrazine used in bio-orthogonal drug activation
|
ES2981703T3
(es)
|
2016-09-02 |
2024-10-10 |
Lentigen Tech Inc |
Composiciones y métodos para tratar cáncer con DuoCars
|
JP7138350B2
(ja)
|
2016-11-14 |
2022-09-16 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ. |
共役連結体、該連結体を含有する細胞結合分子-薬物共役体、並びに該共役体及び連結体の使用及び製造方法
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
ES2936803T3
(es)
|
2017-01-09 |
2023-03-22 |
Lentigen Tech Inc |
Composiciones y métodos para tratar el cáncer con inmunoterapia antimesotelina
|
WO2018175994A1
(en)
|
2017-03-24 |
2018-09-27 |
Seattle Genetics, Inc. |
Process for the preparation of glucuronide drug-linkers and intermediates thereof
|
US10426797B2
(en)
|
2017-03-24 |
2019-10-01 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD33 immunotherapy
|
WO2018195302A1
(en)
|
2017-04-19 |
2018-10-25 |
Bluefin Biomedicine, Inc. |
Anti-vtcn1 antibodies and antibody drug conjugates
|
CN111315414A
(zh)
|
2017-06-22 |
2020-06-19 |
梅尔莎纳医疗公司 |
产生载药聚合物支架和蛋白-聚合物-药物缀合物的方法
|
US20200207859A1
(en)
|
2017-07-26 |
2020-07-02 |
Sutro Biopharma, Inc. |
Methods of using anti-cd74 antibodies and antibody conjugates in treatment of t-cell lymphoma
|
CA3071624A1
(en)
|
2017-07-31 |
2019-02-07 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-cd19/cd20 immunotherapy
|
CN119120527A
(zh)
|
2017-09-15 |
2024-12-13 |
莱蒂恩技术公司 |
用于用抗cd19免疫治疗来治疗癌症的组合物和方法
|
US10596270B2
(en)
|
2017-09-18 |
2020-03-24 |
Sutro Biopharma, Inc. |
Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates
|
JP7275118B2
(ja)
|
2017-10-16 |
2023-05-17 |
レンティジェン・テクノロジー・インコーポレイテッド |
抗cd22免疫療法によってがんを処置するための組成物および方法
|
WO2019094709A1
(en)
|
2017-11-09 |
2019-05-16 |
Pettit George R |
Betulastatin compounds
|
US10894819B2
(en)
|
2017-12-20 |
2021-01-19 |
Lentigen Technology, Inc. |
Compositions and methods for treating HIV/AIDS with immunotherapy
|
EP3787691A1
(de)
|
2018-05-04 |
2021-03-10 |
Tagworks Pharmaceuticals B.V. |
Tetrazine für hohe clickkonjugationsausbeute in vivo und hohe clickfreisetzungsausbeute
|
WO2019212357A1
(en)
|
2018-05-04 |
2019-11-07 |
Tagworks Pharmaceuticals B.V. |
Compounds comprising a linker for increasing transcyclooctene stability
|
WO2020006347A1
(en)
|
2018-06-29 |
2020-01-02 |
Boehringer Ingelheim International Gmbh |
Anti-cd40 antibodies for use in treating autoimmune disease
|
EP3820909B1
(de)
|
2018-07-11 |
2023-03-01 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Monoklonaler antikörper zum nachweis des antiviralen arzneimittels emtricitabin (ftc, 2',3'-dideoxy-5-fluoro-3'-thiacytidin)
|
EP3852811A1
(de)
|
2018-09-17 |
2021-07-28 |
Sutro Biopharma, Inc. |
Kombinationstherapien mit anti-folat-rezeptor-antikörper-konjugaten
|
AU2019343184A1
(en)
|
2018-09-20 |
2021-04-15 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD123 immunotherapy
|
CN118581122A
(zh)
|
2018-09-26 |
2024-09-03 |
莱蒂恩技术公司 |
用于用抗cd19/cd22免疫治疗来治疗癌症的组合物和方法
|
US20230021500A1
(en)
|
2018-10-29 |
2023-01-26 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
EP3886895A1
(de)
|
2018-11-30 |
2021-10-06 |
Lentigen Technology, Inc. |
Zusammensetzungen und verfahren zur behandlung von krebs mit anti-cd38-immuntherapie
|
EP3898699A1
(de)
|
2018-12-19 |
2021-10-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren und zusammensetzungen zur behandlung von krebs durch immunmodulation unter verwendung von antikörpern gegen cathespin-d
|
WO2020181164A1
(en)
|
2019-03-06 |
2020-09-10 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with self-driving chimeric antigen receptors
|
EP3962951A1
(de)
|
2019-05-03 |
2022-03-09 |
Sutro Biopharma, Inc. |
Anti-bcma-antikörper-konjugate
|
CA3140102A1
(en)
|
2019-05-30 |
2020-12-03 |
Dina SCHNEIDER |
Compositions and methods for treating cancer with anti-bcma immunotherapy
|
ES2981364T3
(es)
|
2019-06-17 |
2024-10-08 |
Tagworks Pharmaceuticals B V |
Compuestos para liberación clic rápida y eficiente
|
IL289094A
(en)
|
2019-06-17 |
2022-02-01 |
Tagworks Pharmaceuticals B V |
Tetrazines for increasing the speed and yield of the "click release" reaction
|
JP2022539589A
(ja)
|
2019-07-02 |
2022-09-12 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
EGFRvIIIと結合するモノクローナル抗体およびその使用
|
EP3812008A1
(de)
|
2019-10-23 |
2021-04-28 |
Gamamabs Pharma |
Amh-kompetitiver antagonistischer antikörper
|
TW202138388A
(zh)
|
2019-12-30 |
2021-10-16 |
美商西根公司 |
以非海藻糖苷化抗-cd70抗體治療癌症之方法
|
WO2021178597A1
(en)
|
2020-03-03 |
2021-09-10 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
JP2023532448A
(ja)
|
2020-06-22 |
2023-07-28 |
レンティジェン・テクノロジー・インコーポレイテッド |
Tslpr-cd19またはtslpr-cd22免疫療法によりがんを処置するための組成物および方法
|
WO2022061061A1
(en)
|
2020-09-21 |
2022-03-24 |
Boehringer Ingelheim International Gmbh |
Use of anti-cd40 antibodies for treatment of inflammatory conditions
|
CA3171093A1
(en)
|
2020-11-05 |
2022-05-12 |
Dina SCHNEIDER |
Compositions and methods for treating cancer with anti-cd19/cd22 immunotherapy
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
EP4291227A2
(de)
|
2021-02-15 |
2023-12-20 |
Takeda Pharmaceutical Company Limited |
Zelltherapiezusammensetzungen und verfahren zur modulierung der tgf-b-signalisierung
|
CN117396231A
(zh)
|
2021-04-30 |
2024-01-12 |
新基公司 |
使用抗BCMA抗体药物缀合物(ADC)与γ分泌酶抑制剂(GSI)的组合的组合疗法
|
AU2022304582A1
(en)
|
2021-06-29 |
2024-02-01 |
Seagen Inc. |
Methods of treating cancer with a combination of a nonfucosylated anti-cd70 antibody and a cd47 antagonist
|
CN118119409A
(zh)
|
2021-09-03 |
2024-05-31 |
东丽株式会社 |
癌的治疗和/或预防用药物组合物
|
CA3230774A1
(en)
|
2021-09-06 |
2023-03-09 |
Veraxa Biotech Gmbh |
Novel aminoacyl-trna synthetase variants for genetic code expansion in eukaryotes
|
AU2022395626A1
(en)
|
2021-11-25 |
2024-05-30 |
Veraxa Biotech Gmbh |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
EP4186529A1
(de)
|
2021-11-25 |
2023-05-31 |
Veraxa Biotech GmbH |
Verbesserte antikörper-nutzlast-konjugate (aps), hergestellt durch ortsspezifische konjugation mittels genetischer codeerweiterung
|
KR20240119102A
(ko)
|
2021-12-08 |
2024-08-06 |
유럽피안 몰레큘러 바이올로지 래보러토리 |
표적화 접합체의 제조를 위한 친수성 테트라진-관능화 페이로드
|
EP4314031B1
(de)
|
2022-02-15 |
2024-03-13 |
Tagworks Pharmaceuticals B.V. |
Maskiertes il12-protein
|
US11590169B1
(en)
|
2022-03-02 |
2023-02-28 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with anti-CD123 immunotherapy
|
US20230338424A1
(en)
|
2022-03-02 |
2023-10-26 |
Lentigen Technology, Inc. |
Compositions and Methods for Treating Cancer with Anti-CD123 Immunotherapy
|
WO2024006542A1
(en)
|
2022-06-30 |
2024-01-04 |
Sutro Biopharma, Inc. |
Anti-ror1 antibodies and antibody conjugates, compositions comprising anti-ror1 antibodies or antibody conjugates, and methods of making and using anti-ror1 antibodies and antibody conjugates
|
WO2024013724A1
(en)
|
2022-07-15 |
2024-01-18 |
Pheon Therapeutics Ltd |
Antibody-drug conjugates
|
WO2024026107A2
(en)
|
2022-07-28 |
2024-02-01 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating solid tumors
|
WO2024044743A1
(en)
|
2022-08-26 |
2024-02-29 |
Lentigen Technology, Inc. |
Compositions and methods for treating cancer with fully human anti-cd20/cd19 immunotherapy
|
WO2024080872A1
(en)
|
2022-10-12 |
2024-04-18 |
Tagworks Pharmaceuticals B.V. |
Strained bicyclononenes
|
WO2024153789A1
(en)
|
2023-01-20 |
2024-07-25 |
Basf Se |
Stabilized biopolymer composition, their manufacture and use
|
WO2024191293A1
(en)
|
2023-03-10 |
2024-09-19 |
Tagworks Pharmaceuticals B.V. |
Trans-cyclooctene with improved t-linker
|
WO2024197151A2
(en)
|
2023-03-22 |
2024-09-26 |
Salubris Biotherapeutics, Inc. |
Anti-5t4 antigen binding domains, antibody-drug conjugates and methods of use thereof
|
WO2024236156A1
(en)
|
2023-05-17 |
2024-11-21 |
Institut National de la Santé et de la Recherche Médicale |
Anti-cathepsin-d antibodies
|
WO2025014896A1
(en)
|
2023-07-07 |
2025-01-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Humanized 40h3 antibody
|
WO2025021929A1
(en)
|
2023-07-27 |
2025-01-30 |
Veraxa Biotech Gmbh |
Hydrophilic trans-cyclooctene (hytco) compounds, constructs and conjugates containing the same
|