ATE215554T1 - Radionuklidmarkierung von vitamin b12 und deren coenzyme - Google Patents

Radionuklidmarkierung von vitamin b12 und deren coenzyme

Info

Publication number
ATE215554T1
ATE215554T1 AT96942005T AT96942005T ATE215554T1 AT E215554 T1 ATE215554 T1 AT E215554T1 AT 96942005 T AT96942005 T AT 96942005T AT 96942005 T AT96942005 T AT 96942005T AT E215554 T1 ATE215554 T1 AT E215554T1
Authority
AT
Austria
Prior art keywords
coenzymes
vitamin
cobalamin
radionuclide labeling
group
Prior art date
Application number
AT96942005T
Other languages
English (en)
Inventor
Douglas A Collins
Henricus P C Hogenkamp
Original Assignee
Mayo Foundation
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation, Univ Minnesota filed Critical Mayo Foundation
Application granted granted Critical
Publication of ATE215554T1 publication Critical patent/ATE215554T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96942005T 1995-11-13 1996-11-12 Radionuklidmarkierung von vitamin b12 und deren coenzyme ATE215554T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/557,955 US5739313A (en) 1995-11-13 1995-11-13 Radionuclide labeling of vitamin B12 and coenzymes thereof
PCT/US1996/018334 WO1997018231A1 (en) 1995-11-13 1996-11-12 Radionuclide labeling of vitamin b12 and coenzymes thereof

Publications (1)

Publication Number Publication Date
ATE215554T1 true ATE215554T1 (de) 2002-04-15

Family

ID=24227541

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96942005T ATE215554T1 (de) 1995-11-13 1996-11-12 Radionuklidmarkierung von vitamin b12 und deren coenzyme

Country Status (12)

Country Link
US (8) US5739313A (de)
EP (1) EP0883627B1 (de)
JP (1) JP4156667B2 (de)
AT (1) ATE215554T1 (de)
AU (2) AU702026B2 (de)
CA (2) CA2237263C (de)
DE (1) DE69620467T2 (de)
DK (1) DK0883627T3 (de)
ES (1) ES2175162T3 (de)
NZ (1) NZ324114A (de)
PT (1) PT883627E (de)
WO (1) WO1997018231A1 (de)

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DE69620467D1 (de) 2002-05-08
AU1119597A (en) 1997-06-05
US6096290A (en) 2000-08-01
US20050069493A1 (en) 2005-03-31
PT883627E (pt) 2002-09-30
AU702026B2 (en) 1999-02-11
NZ324114A (en) 2000-01-28
CA2237263C (en) 2001-07-31
JP2000500753A (ja) 2000-01-25
JP4156667B2 (ja) 2008-09-24
US6004533A (en) 1999-12-21
US6613305B1 (en) 2003-09-02
US20090162281A1 (en) 2009-06-25
WO1997018231A1 (en) 1997-05-22
EP0883627A1 (de) 1998-12-16
US7141233B2 (en) 2006-11-28
US5739313A (en) 1998-04-14
US7462345B2 (en) 2008-12-09
AU719545B2 (en) 2000-05-11
CA2351207A1 (en) 1997-05-22
EP0883627B1 (de) 2002-04-03
US20070110667A1 (en) 2007-05-17
CA2351207C (en) 2006-05-23
DK0883627T3 (da) 2002-07-15
ES2175162T3 (es) 2002-11-16
DE69620467T2 (de) 2002-11-21
CA2237263A1 (en) 1997-05-22
US6211355B1 (en) 2001-04-03
AU2499999A (en) 1999-06-17

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