FI933506A - Bisyklopolyatsamakrosyklokarboksyylihappokomplekseja, niiden konjugaatteja, menetelmä niiden valmistamiseksi ja käyttö varjoaineina - Google Patents

Bisyklopolyatsamakrosyklokarboksyylihappokomplekseja, niiden konjugaatteja, menetelmä niiden valmistamiseksi ja käyttö varjoaineina Download PDF

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Publication number
FI933506A
FI933506A FI933506A FI933506A FI933506A FI 933506 A FI933506 A FI 933506A FI 933506 A FI933506 A FI 933506A FI 933506 A FI933506 A FI 933506A FI 933506 A FI933506 A FI 933506A
Authority
FI
Finland
Prior art keywords
conjugates
preparation
contrast agents
acid complexes
bicyclopolyazamacrocyclocarboxylic
Prior art date
Application number
FI933506A
Other languages
English (en)
Swedish (sv)
Other versions
FI933506A0 (fi
Inventor
Garry E Kiefer
Jaime Simon
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002139738A external-priority patent/CA2139738A1/en
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of FI933506A0 publication Critical patent/FI933506A0/fi
Publication of FI933506A publication Critical patent/FI933506A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
FI933506A 1993-05-06 1993-08-09 Bisyklopolyatsamakrosyklokarboksyylihappokomplekseja, niiden konjugaatteja, menetelmä niiden valmistamiseksi ja käyttö varjoaineina FI933506A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1993/004322 WO1994026313A1 (en) 1993-05-06 1993-05-06 Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
CA002139738A CA2139738A1 (en) 1993-05-06 1993-05-06 Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents

Publications (2)

Publication Number Publication Date
FI933506A0 FI933506A0 (fi) 1993-08-09
FI933506A true FI933506A (fi) 1994-11-07

Family

ID=25677723

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933506A FI933506A (fi) 1993-05-06 1993-08-09 Bisyklopolyatsamakrosyklokarboksyylihappokomplekseja, niiden konjugaatteja, menetelmä niiden valmistamiseksi ja käyttö varjoaineina

Country Status (2)

Country Link
FI (1) FI933506A (fi)
WO (1) WO1994026313A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5450235A (en) 1993-10-20 1995-09-12 Minnesota Mining And Manufacturing Company Flexible cube-corner retroreflective sheeting
US6207826B1 (en) 1995-03-27 2001-03-27 Isis Pharmaceuticals, Inc. Macrocyclic compounds having nitrogen-containing linkages
WO1996030377A1 (en) 1995-03-27 1996-10-03 Isis Pharmaceuticals, Inc. Nitrogenous macrocyclic compounds
JP2004509924A (ja) * 2000-09-25 2004-04-02 ザ、プロクター、エンド、ギャンブル、カンパニー Ｍｒｉ画像増強組成物
NO331773B1 (no) * 2009-12-18 2012-03-26 Ge Healthcare As Mangankelater, sammensetninger omfattende slike og anvendelse av disse som kontrastmidler for magnettomografi (MR)
GB201610738D0 (en) 2016-06-20 2016-08-03 Ge Healthcare As Chelate compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3825040A1 (de) * 1988-07-20 1990-01-25 Schering Ag 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant
DE3938992A1 (de) * 1989-11-21 1991-05-23 Schering Ag Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
GB9001245D0 (en) * 1990-01-19 1990-03-21 Salutar Inc Compounds
JP3131219B2 (ja) * 1990-01-19 2001-01-31 ニユコメド・イメージング・アクシエセルカペト キレート化合物

Also Published As

Publication number Publication date
WO1994026313A1 (en) 1994-11-24
FI933506A0 (fi) 1993-08-09

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