ATE206304T1 - Bioadhesive feste arzneimittelform - Google Patents

Bioadhesive feste arzneimittelform

Info

Publication number
ATE206304T1
ATE206304T1 AT96944692T AT96944692T ATE206304T1 AT E206304 T1 ATE206304 T1 AT E206304T1 AT 96944692 T AT96944692 T AT 96944692T AT 96944692 T AT96944692 T AT 96944692T AT E206304 T1 ATE206304 T1 AT E206304T1
Authority
AT
Austria
Prior art keywords
solid drug
drug form
dosage forms
solid dosage
bioadhesive
Prior art date
Application number
AT96944692T
Other languages
English (en)
Inventor
Paul Marie Victor Gilis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE206304T1 publication Critical patent/ATE206304T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96944692T 1995-12-27 1996-12-20 Bioadhesive feste arzneimittelform ATE206304T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95203649 1995-12-27
PCT/EP1996/005884 WO1997024109A1 (en) 1995-12-27 1996-12-20 Bioadhesive solid dosage form

Publications (1)

Publication Number Publication Date
ATE206304T1 true ATE206304T1 (de) 2001-10-15

Family

ID=8221021

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96944692T ATE206304T1 (de) 1995-12-27 1996-12-20 Bioadhesive feste arzneimittelform

Country Status (27)

Country Link
US (1) US6303147B1 (de)
EP (1) EP0869772B1 (de)
JP (1) JP4317264B2 (de)
KR (1) KR100459029B1 (de)
CN (1) CN1146401C (de)
AT (1) ATE206304T1 (de)
AU (1) AU713849B2 (de)
BR (1) BR9612291A (de)
CA (1) CA2232152C (de)
CY (1) CY2269B1 (de)
CZ (1) CZ298690B6 (de)
DE (1) DE69615704T2 (de)
DK (1) DK0869772T3 (de)
EA (1) EA000818B1 (de)
ES (1) ES2164940T3 (de)
HK (1) HK1015680A1 (de)
HU (1) HU228350B1 (de)
IL (1) IL123636A (de)
NO (1) NO320015B1 (de)
NZ (1) NZ325844A (de)
PL (1) PL186278B1 (de)
PT (1) PT869772E (de)
SI (1) SI0869772T1 (de)
SK (1) SK283370B6 (de)
TR (1) TR199800894T2 (de)
WO (1) WO1997024109A1 (de)
ZA (1) ZA9610886B (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
EP1117384A1 (de) * 1998-10-01 2001-07-25 Elan Pharma International Limited Nanopartikelformulierungen mit kontrollierter wirkstofffreisetzung
US20080213378A1 (en) * 1998-10-01 2008-09-04 Elan Pharma International, Ltd. Nanoparticulate statin formulations and novel statin combinations
US6428814B1 (en) * 1999-10-08 2002-08-06 Elan Pharma International Ltd. Bioadhesive nanoparticulate compositions having cationic surface stabilizers
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
EA005291B1 (ru) 1999-03-31 2004-12-30 Янссен Фармацевтика Н.В. Применение предварительно желатинированного крахмала в композиции с контролируемым высвобождением
US7503493B2 (en) * 1999-10-25 2009-03-17 Silverbrook Research Pty Ltd Method and system for digitizing freehand graphics with user-selected properties
US20040156872A1 (en) * 2000-05-18 2004-08-12 Elan Pharma International Ltd. Novel nimesulide compositions
US7198795B2 (en) * 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
EP1236466B1 (de) * 2001-02-28 2011-09-21 Axiomedic Ltd. Feste selbst-haftende Zusammensetzungen zur topischen Behandlung von Störungen der Mundschleimhaut
US8980334B2 (en) * 2001-02-28 2015-03-17 Axiomedic Ltd. Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders
FR2827517B1 (fr) * 2001-07-23 2003-10-24 Bioalliance Pharma Systemes therapeutiques bioadhesifs a liberation prolongee
US20030083286A1 (en) * 2001-08-22 2003-05-01 Ching-Leou Teng Bioadhesive compositions and methods for enhanced intestinal drug absorption
US20030124196A1 (en) * 2001-08-22 2003-07-03 Susan Weinbach Pulsatile release compositions and methods for enhanced intestinal drug absorption
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
US7846478B2 (en) * 2002-01-31 2010-12-07 Henkel Ag & Co. Kgaa Bioadhesive composition
PT1471887E (pt) 2002-02-04 2010-07-16 Elan Pharma Int Ltd ComposiãŽes de nanopartculas com lisozima como um estabilizador superficial
WO2004006959A1 (en) * 2002-07-16 2004-01-22 Elan Pharma International, Ltd Liquid dosage compositions of stable nanoparticulate active agents
MY142204A (en) 2002-07-25 2010-10-29 Pharmacia Corp Pramipexole once-daily dosage form
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
WO2005032554A1 (en) 2003-10-03 2005-04-14 Astron Research Pvt. Ltd A novel transmucosal delivery system
US20080234353A1 (en) * 2004-03-24 2008-09-25 Reynir Eyjolfsson Formulations of Ramipril
WO2005102287A2 (en) * 2004-04-22 2005-11-03 Duocort Ab Pharmaceutical compositions for acute glucocorticoid therapy
TWI338583B (en) * 2004-05-20 2011-03-11 Otsuka Pharma Co Ltd Solid pharmaceutical formulation
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
NZ553645A (en) 2004-08-13 2010-09-30 Boehringer Ingelheim Int Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof
US20070048369A1 (en) * 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet
GB0518129D0 (en) * 2005-09-06 2005-10-12 Arrow Int Ltd Ramipril formulation
US20070098782A1 (en) * 2005-10-28 2007-05-03 Selamine Limited Ramipril Formulation
GB2431579A (en) * 2005-10-28 2007-05-02 Arrow Int Ltd Ramipril formulations
US8349120B2 (en) * 2006-03-07 2013-01-08 Ora Health Corporation Multi-layer patch made on a sheet and enclosed in a blister
EP1837020A1 (de) 2006-03-24 2007-09-26 Bioalliance Pharma Bioadhäsive Schleimhautträger zur langsamen Verabreichung von aktiven Substanzen
US20070248655A1 (en) * 2006-04-21 2007-10-25 Haley Jeffrey T Lenticular shaped protective mouth sore discs
US20070293587A1 (en) * 2006-05-23 2007-12-20 Haley Jeffrey T Combating sinus, throat, and blood infections with xylitol delivered in the mouth
KR101474871B1 (ko) * 2006-05-23 2014-12-19 오라헬쓰 코포레이션 아카시아 껌 접착제를 갖는 2층 구강 접착 정제
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
CA2657533A1 (en) * 2006-07-12 2008-01-17 Controlled Therapeutics (Scotland) Ltd. Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
US8974825B2 (en) * 2007-07-06 2015-03-10 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
EP2942053A1 (de) 2007-07-06 2015-11-11 Lupin Limited Pharmazeutische Zusammensetzungen zur Wirkstoffverabreichung im Magen-Darm-Trakt
US20120027855A1 (en) 2007-07-06 2012-02-02 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
EP2163240A1 (de) * 2008-09-12 2010-03-17 Universita' Degli Studi Di Genova Verfahren zur Herstellung von bioadhesiven Kompaktmatrizen
WO2012087966A2 (en) 2010-12-20 2012-06-28 E. I. Du Pont De Nemours And Company Targeted perhydrolases
AU2014224238B2 (en) * 2013-03-06 2016-07-14 Novartis Ag Formulations of organic compounds
CN105193768A (zh) * 2015-08-27 2015-12-30 武汉武药科技有限公司 一种曲安奈德口腔粘贴片及其制备工艺
ES2957388T3 (es) * 2016-07-15 2024-01-18 H2 Water Tech Ltd Composición para producir agua rica en hidrógeno

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3554764A (en) * 1967-12-21 1971-01-12 Gen Foods Corp Freeze-thaw resistant flour and starch thickener blend
DE3739690A1 (de) * 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
EP0451433B1 (de) * 1990-04-12 1996-10-23 Janssen Pharmaceutica N.V. Zusammensetzung zur Anwendung eines Arzneimittels, bestehend aus einem Bioadhäsiven Trägerstoff mit verzögerter Freisetzung
US5330761A (en) * 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5662933A (en) * 1993-09-09 1997-09-02 Edward Mendell Co., Inc. Controlled release formulation (albuterol)
US5370878A (en) 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
TW355683B (en) 1994-02-17 1999-04-11 Janssen Pharmaceutica Nv Composition containing micronized nebivolol
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5656283A (en) 1995-06-08 1997-08-12 Ortho Pharmaceutical Corporation In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product

Also Published As

Publication number Publication date
NO981027D0 (no) 1998-03-09
IL123636A (en) 2001-04-30
SK88798A3 (en) 1998-11-04
CN1146401C (zh) 2004-04-21
SI0869772T1 (en) 2002-04-30
HUP9802913A3 (en) 2000-06-28
SK283370B6 (sk) 2003-06-03
TR199800894T2 (xx) 1998-08-21
EA000818B1 (ru) 2000-04-24
JP4317264B2 (ja) 2009-08-19
DE69615704D1 (de) 2001-11-08
CN1200667A (zh) 1998-12-02
NO981027L (no) 1998-06-15
CA2232152C (en) 2007-02-06
HK1015680A1 (en) 1999-10-22
DK0869772T3 (da) 2002-01-21
KR19990067112A (ko) 1999-08-16
ES2164940T3 (es) 2002-03-01
CY2269B1 (en) 2003-07-04
PT869772E (pt) 2002-03-28
BR9612291A (pt) 1999-07-13
NO320015B1 (no) 2005-10-10
EP0869772A1 (de) 1998-10-14
PL186278B1 (pl) 2003-12-31
PL326196A1 (en) 1998-08-31
EA199800350A1 (ru) 1998-10-29
ZA9610886B (en) 1998-06-23
CZ199298A3 (cs) 1998-09-16
WO1997024109A1 (en) 1997-07-10
DE69615704T2 (de) 2002-07-11
JP2000502691A (ja) 2000-03-07
HUP9802913A2 (hu) 1999-06-28
CZ298690B6 (cs) 2007-12-27
IL123636A0 (en) 1998-10-30
NZ325844A (en) 1999-06-29
AU713849B2 (en) 1999-12-09
CA2232152A1 (en) 1997-07-10
AU1308597A (en) 1997-07-28
HU228350B1 (hu) 2013-03-28
KR100459029B1 (ko) 2006-03-27
US6303147B1 (en) 2001-10-16
EP0869772B1 (de) 2001-10-04

Similar Documents

Publication Publication Date Title
ATE206304T1 (de) Bioadhesive feste arzneimittelform
KR950007841A (ko) 트라마돌 염을 함유하는 서방성 약물 제제
BG105857A (en) Pregelatinized starch in a controlled release formulation
UA41346C2 (uk) Фармацевтична композиція, яка містить флуоксетин або його сіль, таблетка на її основі, спосіб виробництва таблетки, яка диспергується
KR890001526A (ko) 경구용 서방성 아세트 아미노펜 제형 및 이의 제조방법
WO2003047519A3 (en) 'compressed annular tablet with molded triturate tablet for oral and intraoral'
MY118371A (en) Tetrahydrolipstatin containing compositions
ES534096A0 (es) Procedimiento de obtencion de tabletas farmaceuticas administrables por via oral
PT92069A (pt) Processo para a producao de um sistema de distribuicao de drogas
NZ507566A (en) Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants
CA2445519A1 (en) Method for manufacturing a low dose pharmaceutical composition
CA2385890A1 (en) Controlled release compositions comprising nimesulide
FR2698788B1 (fr) Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
CA2214026A1 (en) Pharmaceutical compositions comprising monoamine oxidase b inhibitors
TNSN04048A1 (en) Dosage regimen and pharmaceutical composition for emergency contraception
PT975348E (pt) Composicoes de tibolona estabilizadas
AP1485A (en) Orally administered controlled delivery system for once daily administration of ciprofloxacin.
CA2348474A1 (en) Pharmaceutically active composition and dispensing device
HUP9901208A2 (hu) (R)-5-Bróm-n-(1-etil-4-metil-hexahidro-1H-1,4-diazepin-6-il)-2-metoxi-6-(metil-amino)-3-piridin-karboxamid, eljárás előállítására és ezt a vegyületet tartalmazó gyógyászati készítmény
SE9403389D0 (sv) Pharmaceutical composition containing derivattves of sex hormones
AR002727A1 (es) El uso de ridogrel para la fabricacion de un medicamento util para el tratamiento de enfermedades digestivas inflamatorias, una composicionfarmaceutica que comprende ridogrel y un procedimiento para preparar dicha composicion.
TH59375A3 (th) สูตรผสมทางเภสัช ที่ซึ่งการปลดปล่อยออกได้ถูกควบคุม
KR950016757A (ko) 약물중독 치료제 조성물

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner