ATE201704T1 - Harnstoff- und urethangruppen enthaltendes lineares blockpolymer, verfahren zur herstellung von linearen blockpolymeren sowie verwendung der blockpolymeren als implantate - Google Patents

Harnstoff- und urethangruppen enthaltendes lineares blockpolymer, verfahren zur herstellung von linearen blockpolymeren sowie verwendung der blockpolymeren als implantate

Info

Publication number
ATE201704T1
ATE201704T1 AT96942698T AT96942698T ATE201704T1 AT E201704 T1 ATE201704 T1 AT E201704T1 AT 96942698 T AT96942698 T AT 96942698T AT 96942698 T AT96942698 T AT 96942698T AT E201704 T1 ATE201704 T1 AT E201704T1
Authority
AT
Austria
Prior art keywords
linear block
block polymers
implants
urethane groups
polymer containing
Prior art date
Application number
AT96942698T
Other languages
German (de)
English (en)
Inventor
Per Flodin
Original Assignee
Artimplant Dev Artdev Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artimplant Dev Artdev Ab filed Critical Artimplant Dev Artdev Ab
Application granted granted Critical
Publication of ATE201704T1 publication Critical patent/ATE201704T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/67—Unsaturated compounds having active hydrogen
    • C08G18/675—Low-molecular-weight compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4236—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups
    • C08G18/4238—Polycondensates having carboxylic or carbonic ester groups in the main chain containing only aliphatic groups derived from dicarboxylic acids and dialcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269—Lactones
    • C08G18/4277—Caprolactone and/or substituted caprolactone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
AT96942698T 1995-12-15 1996-11-25 Harnstoff- und urethangruppen enthaltendes lineares blockpolymer, verfahren zur herstellung von linearen blockpolymeren sowie verwendung der blockpolymeren als implantate ATE201704T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9504495A SE505703C2 (sv) 1995-12-15 1995-12-15 Linjär blockpolymer innefattande urea- och uretangrupper, förfarande för framställning av linjära blockpolymerer samt användning av blockpolymererna som implantat
PCT/SE1996/001530 WO1997022643A1 (en) 1995-12-15 1996-11-25 Linear block polymer comprising urea and urethane groups, method for the production of linear block polymers and use of the block polymers as implants

Publications (1)

Publication Number Publication Date
ATE201704T1 true ATE201704T1 (de) 2001-06-15

Family

ID=20400606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96942698T ATE201704T1 (de) 1995-12-15 1996-11-25 Harnstoff- und urethangruppen enthaltendes lineares blockpolymer, verfahren zur herstellung von linearen blockpolymeren sowie verwendung der blockpolymeren als implantate

Country Status (26)

Country Link
US (1) US6210441B1 (enExample)
EP (1) EP0866816B1 (enExample)
JP (1) JP4059524B2 (enExample)
KR (1) KR20000064383A (enExample)
CN (1) CN1152899C (enExample)
AT (1) ATE201704T1 (enExample)
AU (1) AU709440B2 (enExample)
BR (1) BR9612032A (enExample)
CA (1) CA2240061A1 (enExample)
CZ (1) CZ179398A3 (enExample)
DE (1) DE69613144T2 (enExample)
DK (1) DK0866816T3 (enExample)
ES (1) ES2159769T3 (enExample)
GR (1) GR3036469T3 (enExample)
HU (1) HUP9901201A3 (enExample)
IL (1) IL124884A (enExample)
NO (1) NO982703L (enExample)
NZ (1) NZ324479A (enExample)
PL (1) PL327246A1 (enExample)
PT (1) PT866816E (enExample)
RU (1) RU2189993C2 (enExample)
SE (1) SE505703C2 (enExample)
SI (1) SI0866816T1 (enExample)
SK (1) SK79798A3 (enExample)
TR (1) TR199801091T2 (enExample)
WO (1) WO1997022643A1 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE510868C2 (sv) 1997-11-03 1999-07-05 Artimplant Dev Artdev Ab Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar
SE513491C2 (sv) 1998-12-15 2000-09-18 Artimplant Dev Artdev Ab Implantat för insättning i människor eller djur innefattande böjliga trådformiga element
SE514064C2 (sv) 1999-02-02 2000-12-18 Artimplant Dev Artdev Ab Film för medicinsk användning bestående av linjära blockpolymerer av polyuretaner samt förfarande för framställning av en sådan film
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
SE0101523L (sv) * 2000-12-29 2002-06-30 Artimplant Ab Linjär polymer
AR032052A1 (es) * 2000-12-29 2003-10-22 Artimplant Ab Polimero lineal de bloques, procedimiento para su preparacion, su uso, implantes, material para relleno, composiciones farmaceuticas y material polimerico poroso que comprenden dicho polimero lineal de bloques
SE526106C2 (sv) * 2002-06-20 2005-07-05 Artimplant Ab Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US20050013793A1 (en) * 2003-01-16 2005-01-20 Beckman Eric J. Biodegradable polyurethanes and use thereof
US8791073B2 (en) * 2004-05-14 2014-07-29 William Marsh Rice University Peptide-modified polyurethane compositions and associated methods
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US20070167617A1 (en) * 2006-01-17 2007-07-19 Fitz Benjamin D Method of making a diisocyanate terminated macromer
US20060153796A1 (en) * 2005-01-10 2006-07-13 Fitz Benjamin D Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant
US7968668B2 (en) 2005-01-10 2011-06-28 Ethicon Inc. Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant
US8470954B2 (en) 2005-01-10 2013-06-25 Ethicon, Inc. Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant
US7728097B2 (en) * 2005-01-10 2010-06-01 Ethicon, Inc. Method of making a diisocyanate terminated macromer
EP1700872A3 (en) * 2005-03-10 2008-07-23 Radi Medical Systems Ab Polyureaurethane material and method of producing a polyureaurethane material
DE102005033101A1 (de) * 2005-07-15 2007-01-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Resorbierbare Polyetherester und ihre Verwendung zur Herstellung von medizinischen Implantaten
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
JP5178520B2 (ja) * 2005-09-22 2013-04-10 メディバス エルエルシー 固体ポリマー送達組成物およびその使用法
US20070123824A1 (en) * 2005-10-17 2007-05-31 Coaptus Medical Corporation Systems and methods for directing valves that control a vacuum applied to a patient
WO2007050415A2 (en) * 2005-10-21 2007-05-03 Medivas, Llc Poly(ester urea) polymers and methods of use
WO2007067744A2 (en) * 2005-12-07 2007-06-14 Medivas, Llc Method for assembling a polymer-biologic delivery composition
CA2649672C (en) * 2006-05-02 2015-07-07 Medivas, Llc Delivery of ophthalmologic agents to the exterior or interior of the eye
WO2007133616A2 (en) * 2006-05-09 2007-11-22 Medivas, Llc Biodegradable water soluble polymers
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
EP1985319B1 (en) * 2007-04-23 2012-06-13 Jointsphere B.V. Device for cartilage repair
CA2709412A1 (en) * 2007-07-24 2009-01-29 Medivas, Llc Biodegradable cationic polymer gene transfer compositions and methods of use
US8324292B2 (en) * 2008-02-29 2012-12-04 Ethicon, Inc. Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant
US8071663B2 (en) * 2008-02-29 2011-12-06 Ethicon, Inc. Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant
WO2010019716A1 (en) * 2008-08-13 2010-02-18 Medivas, Llc Aabb-poly(depsipeptide) biodegradable polymers and methods of use
US8962784B2 (en) * 2008-12-19 2015-02-24 Ethicon, Inc. Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant
EP2413838A4 (en) * 2009-04-03 2012-09-19 Biomerix Corp AT LEAST PARTIALLY RESORBIBLE RETICULATED ELASTOMER MATRIX PARTICLES AND PRODUCTION METHOD
US9050176B2 (en) 2009-04-03 2015-06-09 Biomerix Corporation At least partially resorbable reticulated elastomeric matrix elements and methods of making same
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
ES2992024T3 (es) 2011-06-23 2024-12-05 Dsm Ip Assets Bv Nuevos copolímeros de poliesteramida biodegradables para la administración de fármacos
TWI641396B (zh) * 2011-09-23 2018-11-21 Bvw控股公司 醫療共聚物
US10434071B2 (en) 2014-12-18 2019-10-08 Dsm Ip Assets, B.V. Drug delivery system for delivery of acid sensitivity drugs
WO2020117763A1 (en) 2018-12-03 2020-06-11 International Life Sciences Llc D/B/A Artelon Eyelet interference screw and methods of use
CN112011049A (zh) * 2019-05-30 2020-12-01 中国科学院化学研究所 一种热塑性聚脲弹性体及其制备方法
CA3160955A1 (en) 2019-11-12 2021-05-20 Dsm Ip Assets B.V. Polyesteramide copolymers possessing high glass transition temperatures

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790976A (fr) * 1971-11-06 1973-05-07 Bayer Ag Derives silyles de l'uree et leur preparation
US4549010A (en) * 1984-06-27 1985-10-22 Merck & Co., Inc. Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal
AU2800489A (en) * 1987-12-02 1989-07-05 Tyndale Plains-Hunter Ltd. Hydrophilic polyurethanes of improved strength
CA2038605C (en) * 1990-06-15 2000-06-27 Leonard Pinchuk Crack-resistant polycarbonate urethane polymer prostheses and the like
WO1992000338A1 (en) * 1990-06-26 1992-01-09 Commonwealth Scientific And Industrial Research Organisation Polyurethane or polyurethane-urea elastomeric compositions
WO1992004390A1 (en) * 1990-09-12 1992-03-19 Polymedica Industries, Inc. Biostable polyurethane products

Also Published As

Publication number Publication date
IL124884A (en) 2002-03-10
EP0866816B1 (en) 2001-05-30
NZ324479A (en) 1999-05-28
NO982703D0 (no) 1998-06-11
CZ179398A3 (cs) 1998-11-11
CA2240061A1 (en) 1997-06-26
DE69613144T2 (de) 2001-11-29
BR9612032A (pt) 1999-12-28
SE9504495L (sv) 1997-06-16
DE69613144D1 (de) 2001-07-05
SK79798A3 (en) 1999-03-12
AU1154797A (en) 1997-07-14
PT866816E (pt) 2001-10-31
ES2159769T3 (es) 2001-10-16
CN1214057A (zh) 1999-04-14
AU709440B2 (en) 1999-08-26
SI0866816T1 (enExample) 2001-10-31
PL327246A1 (en) 1998-12-07
IL124884A0 (en) 1999-01-26
GR3036469T3 (en) 2001-11-30
SE9504495D0 (sv) 1995-12-15
JP2000502142A (ja) 2000-02-22
US6210441B1 (en) 2001-04-03
CN1152899C (zh) 2004-06-09
KR20000064383A (ko) 2000-11-06
RU2189993C2 (ru) 2002-09-27
SE505703C2 (sv) 1997-09-29
DK0866816T3 (da) 2001-09-10
JP4059524B2 (ja) 2008-03-12
HUP9901201A2 (hu) 1999-07-28
EP0866816A1 (en) 1998-09-30
WO1997022643A1 (en) 1997-06-26
NO982703L (no) 1998-07-14
HUP9901201A3 (en) 2000-04-28
TR199801091T2 (xx) 2001-12-21

Similar Documents

Publication Publication Date Title
DE69613144D1 (de) Harnstoff- und urethangruppen enthaltendes lineares blockpolymer, verfahren zur herstellung von linearen blockpolymeren sowie verwendung der blockpolymeren als implantate
DE69826639T2 (de) Chirurgische artikel hergestellt aus polyesteramiden mit von aminosäuren abstammenden gruppen und dazu alternierend mit von alpha-hydroxysäuren abstammenden gruppen
ATE250663T1 (de) Kulturmedium und verfahren zur herstellung von hyaluronsäure mit hohem molekulargewicht
ATE380109T1 (de) Systeme, verfahren und vorrichtungen zur herstellung von dosierformen
DE59601880D1 (de) Verfahren zur herstellung hydrophiler oder teilweise hydrophiler, anorganischer aerogele
DE69826994D1 (de) Bioabbaubare terephthalat polyester-polyphosphat polymere, zusammensetzungen, gegenstände und verfahren für ihre herstellung und verwendung
DE69626996D1 (de) Unter gewebebedingungen abbaubares material und verfahren zu seiner herstellung
DE69928219D1 (de) Lipasehemmende polymere
RU98113712A (ru) Линейный блок-полимер, содержащий группу мочевины и уретановую группу, способ получения линейных блок-полимеров и использование блок-полимеров в качестве имплантатов
DE59305882D1 (de) Mitogenfreie substanz, deren herstellung sowie verwendung
DE69837141D1 (de) Polyhydroxyalkanoate für in vivo anwendungen
ATE388721T1 (de) Alpha interferon-polymer konjugate mit erhöhter biologischer wirksamkeit sowie verfahren zu deren herstellung
ATE169644T1 (de) Verfahren zur herstellung von oh-gruppen enthaltenden copolymerisaten und deren verwendung in festkörperreichen beschichtungsmitteln
US9381251B2 (en) Thermoplastic paste for repairing living tissues
DE69517191D1 (de) Wasserlösliche derivate epipodophyllotoxine, verfahren zu ihrer herstellung, ihre verwendung als medikament und ihre verwendung zur herstellung eines antikrebsmittels
AT501700A1 (de) Mit strahlung härtbare, biologisch abbaubare zusammensetzungen und deren verwendung als stützmaterialien für den knochenersatz
DE69332219D1 (de) Injektion zur heilung von verletztem abnormem gewebe, verfahren zu ihrer herstellung und ihre verwendung
DE59709792D1 (de) Ringannelierte dihydropyrane, verfahren zur herstellung sowie deren verwendung
DE59807490D1 (de) Verfahren zur herstellung halbharter kompakter oder zelliger formkörper auf pur-basis und deren stabilisierung, daraus hergestellte formkörper, sowie deren verwendung
ATE219505T1 (de) Verfahren zur herstellung von polyhydroxycarbonsäure
DE59404739D1 (de) Dextranester, verfahren zu ihrer herstellung und ihre verwendung zur umhüllung oder einbettung von arzneimitteln
DE69313138D1 (de) Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen
EP0991371A4 (en) PROCESS FOR THE TREATMENT OF DENTAL PROSTHESES

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee