ATE190502T1 - Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken - Google Patents

Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken

Info

Publication number
ATE190502T1
ATE190502T1 AT94106827T AT94106827T ATE190502T1 AT E190502 T1 ATE190502 T1 AT E190502T1 AT 94106827 T AT94106827 T AT 94106827T AT 94106827 T AT94106827 T AT 94106827T AT E190502 T1 ATE190502 T1 AT E190502T1
Authority
AT
Austria
Prior art keywords
gram
membrane proteins
outer membrane
lot
preparation
Prior art date
Application number
AT94106827T
Other languages
English (en)
Inventor
Gary W Zlotnick
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE190502T1 publication Critical patent/ATE190502T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94106827T 1993-05-13 1994-05-02 Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken ATE190502T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6158193A 1993-05-13 1993-05-13

Publications (1)

Publication Number Publication Date
ATE190502T1 true ATE190502T1 (de) 2000-04-15

Family

ID=22036711

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94106827T ATE190502T1 (de) 1993-05-13 1994-05-02 Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken

Country Status (11)

Country Link
US (2) US6355253B1 (de)
EP (1) EP0624376B1 (de)
JP (1) JP3711289B2 (de)
KR (1) KR100355961B1 (de)
AT (1) ATE190502T1 (de)
CA (1) CA2123355C (de)
DE (1) DE69423383T2 (de)
DK (1) DK0624376T3 (de)
ES (1) ES2145072T3 (de)
GR (1) GR3033469T3 (de)
PT (1) PT624376E (de)

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DK0991761T3 (da) * 1997-08-21 2008-05-19 Nederlanden Staat Hidtil ukendte mutaner af gramnegative mucosale bakterier og anvendelse deraf i vacciner
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US20070026021A1 (en) * 1998-05-01 2007-02-01 Chiron S.R.I. Neisseria meningitidis antigens and compositions
WO1999061053A1 (en) 1998-05-29 1999-12-02 Chiron Corporation Combination meningitidis b/c vaccines
DK2270173T3 (en) 1999-05-19 2016-03-07 Glaxosmithkline Biolog Sa Neisserial combination compositions
GB9928196D0 (en) * 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
DK1248647T3 (da) * 2000-01-17 2010-09-27 Novartis Vaccines & Diagnostic Ydre membranvesikel (OMV) vaccine omfattende N. meningitidis serogruppe B ydre membranproteiner
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
US7785608B2 (en) * 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
US7301554B2 (en) * 2002-09-20 2007-11-27 Ricoh Company, Ltd. Light scanning device, scanning line adjusting method, scanning line adjusting control method, image forming apparatus, and image forming method
ES2608048T3 (es) 2002-10-11 2017-04-05 Glaxosmithkline Biologicals Sa Vacunas polipeptídicas para protección amplia contra linajes meningocócicos hipervirulentos
EP1581243A4 (de) * 2002-12-06 2008-01-02 Agennix Inc Orales lactoferrin für sepsisbehandlung
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
AU2004312067A1 (en) 2003-12-30 2005-07-21 Wyeth Formulations of hydrophobic proteins in an immunogenic composition having improved tolerability
GB0416120D0 (en) 2004-07-19 2004-08-18 Health Prot Agency Stable compositions containing OMV's
GB0419627D0 (en) * 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
CN101203529A (zh) 2005-02-18 2008-06-18 诺华疫苗和诊断公司 来自脑膜炎/脓毒症相关性大肠杆菌的蛋白质和核酸
SG160329A1 (en) 2005-02-18 2010-04-29 Novartis Vaccines & Diagnostic Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli
KR100612895B1 (ko) * 2005-05-04 2006-08-14 삼성전자주식회사 화학 물질을 이용한 생물학적 시료로부터 단백질의선택적인 제거 방법
EP2064230A2 (de) 2006-08-16 2009-06-03 Novartis AG Immungene aus uropathogenen escherichia coli
AR064642A1 (es) * 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
JP5723768B2 (ja) * 2008-05-30 2015-05-27 ザ ユナイテッド ステイツ オブ アメリカ， アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー， オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ 髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
HUE052850T2 (hu) 2010-08-23 2021-05-28 Wyeth Llc Neisseria meningitidis RLP2086 antigéneket tartalmazó stabil készítmények
GB201015132D0 (en) * 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
NZ607224A (en) 2010-09-10 2014-11-28 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
AU2011300418B2 (en) * 2010-09-10 2016-05-12 Glaxosmithkline Biologicals Sa Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
KR101763625B1 (ko) 2012-03-09 2017-08-01 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
CN104602702B (zh) 2012-09-18 2021-08-27 葛兰素史密丝克莱恩生物有限公司 外膜囊泡
ES2685894T3 (es) 2013-03-08 2018-10-15 Pfizer Inc. Polipéptidos de fusión inmunogénicos
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
EA031589B1 (ru) * 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
EP3270959A1 (de) 2015-02-19 2018-01-24 Pfizer Inc Neisseria meningitidis-zusammensetzungen und verfahren dafür
SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof
CN110568116A (zh) * 2019-09-17 2019-12-13 广东医科大学附属医院 一种筛选用于诊断阿尔茨海默病的生物标志物的方法

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US4386066A (en) * 1981-08-20 1983-05-31 Merck & Co., Inc. Immunogenic complex from N. gonorrhoeae
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EP0351604B1 (de) * 1988-06-29 1994-09-14 The Rockefeller University Neisseria-Vakzine
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US5552146A (en) * 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis

Also Published As

Publication number Publication date
KR100355961B1 (ko) 2002-12-26
DK0624376T3 (da) 2000-07-24
GR3033469T3 (en) 2000-09-29
CA2123355A1 (en) 1994-11-14
EP0624376A1 (de) 1994-11-17
DE69423383D1 (de) 2000-04-20
JPH0819396A (ja) 1996-01-23
US6921537B2 (en) 2005-07-26
JP3711289B2 (ja) 2005-11-02
CA2123355C (en) 2007-08-28
US6355253B1 (en) 2002-03-12
EP0624376B1 (de) 2000-03-15
PT624376E (pt) 2000-07-31
DE69423383T2 (de) 2000-08-24
ES2145072T3 (es) 2000-07-01
US20020136741A1 (en) 2002-09-26

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee