ATE182884T1 - Mittel für behandlung der leber- gallenerkrankungen - Google Patents

Mittel für behandlung der leber- gallenerkrankungen

Info

Publication number
ATE182884T1
ATE182884T1 AT95303718T AT95303718T ATE182884T1 AT E182884 T1 ATE182884 T1 AT E182884T1 AT 95303718 T AT95303718 T AT 95303718T AT 95303718 T AT95303718 T AT 95303718T AT E182884 T1 ATE182884 T1 AT E182884T1
Authority
AT
Austria
Prior art keywords
literary
treatment
diseases
agents
methyl group
Prior art date
Application number
AT95303718T
Other languages
English (en)
Inventor
Ryuji Ueno
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ATE182884T1 publication Critical patent/ATE182884T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95303718T 1994-06-03 1995-05-31 Mittel für behandlung der leber- gallenerkrankungen ATE182884T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12248794 1994-06-03

Publications (1)

Publication Number Publication Date
ATE182884T1 true ATE182884T1 (de) 1999-08-15

Family

ID=14837070

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95303718T ATE182884T1 (de) 1994-06-03 1995-05-31 Mittel für behandlung der leber- gallenerkrankungen

Country Status (14)

Country Link
US (1) US5739161A (de)
EP (1) EP0690049B1 (de)
KR (1) KR100260573B1 (de)
CN (1) CN1076605C (de)
AT (1) ATE182884T1 (de)
AU (1) AU690241B2 (de)
CA (1) CA2150287C (de)
DE (1) DE69511181T2 (de)
DK (1) DK0690049T3 (de)
ES (1) ES2137456T3 (de)
FI (1) FI952721A (de)
GR (1) GR3031066T3 (de)
NO (1) NO308993B1 (de)
NZ (1) NZ272234A (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
TWI225398B (en) 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
JP4332316B2 (ja) 1999-10-15 2009-09-16 スキャンポ・アーゲー 二環式化合物組成物およびその安定化方法
EP1267882B1 (de) 2000-03-24 2009-04-15 Sucampo AG PROSTAGLANDINE zur Behandlung von Lichtstrahlung erzeugten Augenerkrankungen wie Photoretinitis
KR100874626B1 (ko) * 2000-04-06 2008-12-17 수캄포 아게 담즙 분비 촉진 조성물
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
BR0212233A (pt) 2001-08-31 2004-10-05 Sucampo Ag Abridor de canal de cloreto
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
TWI263505B (en) 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
CA2502439C (en) * 2002-10-23 2011-11-22 Sucampo Ag Prostaglandin compounds for the treatment of obesity
AU2003292556B2 (en) 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
US8337891B2 (en) * 2003-07-03 2012-12-25 Sucampo Ag Enteric coated composition comprising prostaglandin analogs as chloride channel opener
JP5222462B2 (ja) 2003-08-21 2013-06-26 スキャンポ・アーゲー 眼科用組成物
JP4690814B2 (ja) * 2004-08-02 2011-06-01 株式会社アールテック・ウエノ プロスタグランジン誘導体の製造法
CN101146541B (zh) * 2005-01-27 2012-04-11 苏坎波公司 用于治疗中枢神经系统疾病的方法和组合物
KR20160120809A (ko) * 2005-03-04 2016-10-18 수캄포 아게 말초 혈관 질환 치료를 위한 방법 및 조성물
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
EP1871380B1 (de) * 2005-04-12 2011-10-19 Sucampo AG Kombinierte verwendung einer prostaglandin-verbindung und eines protonenpumpenhemmers zur behandlung von magen-darm-erkrankungen
US8026393B2 (en) 2006-01-24 2011-09-27 Sucampo Ag Soft-gelatin capsule formulation
MX2008009652A (es) 2006-01-24 2008-11-06 R Tech Ueno Ltd Composicion farmaceutica que comprende un compuesto biciclico y metodo para estabilizar el compuesto biciclico.
WO2007091697A2 (en) * 2006-02-07 2007-08-16 R-Tech Ueno, Ltd. Method for preparing prostaglandin derivative
JP4648340B2 (ja) * 2006-02-07 2011-03-09 株式会社アールテック・ウエノ 15−ケトプロスタグランジンe誘導体の製造法
CA2642744C (en) * 2006-02-28 2015-02-24 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
KR101382922B1 (ko) 2006-03-13 2014-04-08 가부시키가이샤 아루떼꾸 우에노 수성 조성물
US8871752B2 (en) 2008-02-19 2014-10-28 Sucampo Ag Method for modulating stem cell growth
US8609729B2 (en) 2009-04-15 2013-12-17 Sucampo Ag Method for treating macular degeneration
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
EP2694077A4 (de) 2011-04-07 2015-01-21 Sucampo Ag Verfahren zur behandlung von asthenopie
KR20140043075A (ko) * 2011-04-19 2014-04-08 수캄포 아게 사이토카인 활성의 조절 방법
EP2726472B1 (de) * 2011-07-01 2016-12-21 R-Tech Ueno, Ltd. Verfahren zur herstellung eines fettsäurederivats
CN102875586A (zh) * 2011-07-11 2013-01-16 上海天伟生物制药有限公司 一种利马前列素关键中间体的制备方法
RU2648474C2 (ru) 2011-08-05 2018-03-26 Сукампо Аг Способ лечения шизофрении
CN103058907B (zh) * 2011-10-21 2016-05-11 武汉启瑞药业有限公司 鲁比前列酮或其中间体的制备方法
AR092821A1 (es) 2012-04-20 2015-05-06 Sucampo Ag Conjugado de derivado de acido graso-polimero
US20150057351A1 (en) 2013-08-22 2015-02-26 Sucampo Ag Method for treating neuropathic pain
WO2016203317A1 (en) 2015-06-19 2016-12-22 Sucampo Ag Pharmaceutical compositions comprising fatty acid derivative
US10428566B2 (en) * 2017-04-17 2019-10-01 James G. Arendts Flexible unitary sandwich-like panel overhead door

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4306078A (en) * 1979-12-03 1981-12-15 Hoffmann-La Roche Inc. 16-Substituted prostaglandins
US4374856A (en) 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
JPS58164512A (ja) 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS58203911A (ja) 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS62129218A (ja) 1985-12-02 1987-06-11 Teijin Ltd チアプロスタグランジン類を活性成分として含有する肝疾患治療剤
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
JPH0688966B2 (ja) 1987-01-28 1994-11-09 株式会社アールテック・ウエノ プロスタグランジンe類およびそれを含む抗潰瘍剤
JPH0681728B2 (ja) 1987-10-02 1994-10-19 株式会社上野製薬応用研究所 下 剤
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
JP2579193B2 (ja) * 1988-07-19 1997-02-05 小野薬品工業株式会社 16,16−ジフルオロ−15−オキソ−15−デオキシpge誘導体
DD295522A5 (de) * 1989-07-26 1991-11-07 �����@������������������k�� 5-Alkyl-1,3,4-Thiadiazole, Verfahren zu ihrer Herstellung und Verwendung als Schädlingsbekämpfungsmittel
CA2027814C (en) 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds

Also Published As

Publication number Publication date
NZ272234A (en) 1996-02-27
AU2041295A (en) 1995-12-14
EP0690049B1 (de) 1999-08-04
CA2150287C (en) 2004-08-10
DK0690049T3 (da) 2000-03-06
EP0690049A3 (de) 1997-03-26
CN1076605C (zh) 2001-12-26
NO952214L (no) 1995-12-04
FI952721A (fi) 1995-12-04
DE69511181T2 (de) 1999-12-02
AU690241B2 (en) 1998-04-23
EP0690049A2 (de) 1996-01-03
KR960000230A (ko) 1996-01-25
FI952721A0 (fi) 1995-06-02
CN1126591A (zh) 1996-07-17
US5739161A (en) 1998-04-14
NO952214D0 (no) 1995-06-02
KR100260573B1 (ko) 2000-07-01
CA2150287A1 (en) 1995-12-04
GR3031066T3 (en) 1999-12-31
DE69511181D1 (de) 1999-09-09
ES2137456T3 (es) 1999-12-16
NO308993B1 (no) 2000-11-27

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Legal Events

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UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner