DE69534264D1 - Facettenreiches verfahren zur unterdrückung der vermehrung latenter viren in menschen und tieren - Google Patents

Facettenreiches verfahren zur unterdrückung der vermehrung latenter viren in menschen und tieren

Info

Publication number
DE69534264D1
DE69534264D1 DE69534264T DE69534264T DE69534264D1 DE 69534264 D1 DE69534264 D1 DE 69534264D1 DE 69534264 T DE69534264 T DE 69534264T DE 69534264 T DE69534264 T DE 69534264T DE 69534264 D1 DE69534264 D1 DE 69534264D1
Authority
DE
Germany
Prior art keywords
reproduction
animals
viruses
laten
facet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534264T
Other languages
English (en)
Other versions
DE69534264T2 (de
Inventor
Dyke Knox Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HIV Diagnostics Inc
Original Assignee
HIV Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HIV Diagnostics Inc filed Critical HIV Diagnostics Inc
Application granted granted Critical
Publication of DE69534264D1 publication Critical patent/DE69534264D1/de
Publication of DE69534264T2 publication Critical patent/DE69534264T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • A61K38/446Superoxide dismutase (1.15)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2066IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Finger-Pressure Massage (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DE69534264T 1994-10-04 1995-10-02 Facettenreiches verfahren zur unterdrückung der vermehrung latenter viren in menschen und tieren Expired - Lifetime DE69534264T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US317730 1994-10-04
US08/317,730 US5686436A (en) 1993-05-13 1994-10-04 Multi-faceted method to repress reproduction of latent viruses in humans and animals
PCT/US1995/012534 WO1996010402A1 (en) 1994-10-04 1995-10-02 Multi-faceted method to repress reproduction of latent viruses in humans and animals

Publications (2)

Publication Number Publication Date
DE69534264D1 true DE69534264D1 (de) 2005-07-14
DE69534264T2 DE69534264T2 (de) 2006-05-04

Family

ID=23235022

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534264T Expired - Lifetime DE69534264T2 (de) 1994-10-04 1995-10-02 Facettenreiches verfahren zur unterdrückung der vermehrung latenter viren in menschen und tieren

Country Status (9)

Country Link
US (3) US5686436A (de)
EP (1) EP0784471B1 (de)
AT (1) ATE297200T1 (de)
AU (1) AU699871B2 (de)
CA (1) CA2201774C (de)
DE (1) DE69534264T2 (de)
ES (1) ES2243941T3 (de)
PT (1) PT784471E (de)
WO (1) WO1996010402A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4435661C2 (de) * 1994-10-05 1998-07-02 Deutsches Krebsforsch Mittel zur Behandlung von Papillomvirus-positiven gutartigen, malignen und prämalignen Läsionen
TW517089B (en) 1996-09-03 2003-01-11 Res Dev Foundation Assessment of intracellular cysteine and glutathione concentrations
US5874468A (en) * 1996-12-26 1999-02-23 Yissum Brain targeted low molecular weight hydrophobic antioxidant compounds
WO1998029101A1 (en) * 1996-12-31 1998-07-09 Antioxidant Pharmaceuticals Corporation Pharmaceutical preparations of glutathione and methods of administration thereof
DE69841217D1 (de) * 1997-01-13 2009-11-19 Univ Emory Glutathion zur behandlung von influenzainfektionen
DE59712694D1 (de) * 1997-04-18 2006-08-24 Fritz Stanislaus Stabilisiertes arzneimittel enthaltend cysteinylderivate
FR2766712B1 (fr) * 1997-08-01 1999-10-22 Aguettant Lab Composition de preference solution antioxydante et medicaments en faisant application
DE19735120A1 (de) * 1997-08-13 1999-02-18 Peter Hans Prof D Hofschneider Verwendung von Thiolverbindungen zur Inaktivierung von Viren
US6831057B2 (en) 1997-10-28 2004-12-14 The University Of North Carolina At Chapel Hill Use of NF-κB inhibition in combination therapy for cancer
US7186543B1 (en) 1998-07-21 2007-03-06 Gambro Inc. Preparation of vaccines using a photosensitizer and light
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
US6277337B1 (en) 1998-07-21 2001-08-21 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US6242473B1 (en) * 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
FR2792201B1 (fr) * 1999-04-15 2001-11-02 Donatien Mavoungou Procede du renforcement immunitaire et du developpement d'un transporteur lipidique pour une therapie genique anti-vih et anti-bacterienne
WO2000075365A2 (en) 1999-06-08 2000-12-14 University Of Iowa Research Foundation Compounds and methods to enhance raav transduction
EP1200074A2 (de) * 1999-07-16 2002-05-02 Maxim Pharmaceuticals, Inc. Verwendung von diphenyliodonium zur aktivierung und schützung von zytotoxischer lymphozyten
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US7078045B2 (en) * 2000-03-02 2006-07-18 Sang-Geon Kim Pharmaceutical composition for treatment and prevention of liver fibrosis and cirrhosis
KR20030067935A (ko) * 2002-02-09 2003-08-19 김상건 올티프라즈를 포함하는 간경화(간경변증) 치료를 위한 간 조직 재생용 제약 조성물
US7648699B2 (en) 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
US7985588B2 (en) 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
TW590780B (en) 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US20020137704A1 (en) * 2000-06-13 2002-09-26 Markovitz David M. Methods of inhibiting host-cell mediated viral replication
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
WO2001097749A2 (en) * 2000-06-23 2001-12-27 Kotze, Gavin, Salomon The use of synthetic, non-hormonal 21-aminosteroids and thereof
US6756063B2 (en) 2001-03-29 2004-06-29 Zoltan Laboratories, Llc Methods and compositions for the treatment of human and animal cancers
PT1393277E (pt) 2001-05-21 2006-09-29 Alcon Inc Utilizacao de inibidores de nf-kb para tratar disturbios de olho seco
EP1273297A1 (de) * 2001-07-06 2003-01-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Vitamin E für die Behandlung von Krankheiten in denen die Bindung des Transkriptionsfaktors NF-KB und/oder AP-1 an die Zielorte des Promotors einen günstigen Effekt hat (z.B. AIDS, Herzinfarkt)
AT411149B (de) * 2001-07-16 2003-10-27 Gaudernak Elisabeth Verwendung von dithiocarbamaten zur herstellung eines mittels zur behandlung bzw. prävention einer virusinfektion im respiratorischen bereich
CA2454167A1 (en) * 2001-07-16 2003-01-30 Elisabeth Gaudernak Use of a class of antiviral compounds to produce an agent for treating or preventing a virus infection in the respiratory tract
US7199122B2 (en) * 2001-10-02 2007-04-03 Fox Chase Cancer Center Methods for inhibiting angiogenesis
US20030158213A1 (en) * 2001-11-16 2003-08-21 Freeman Bruce A. Xanthine oxidase inhibition as a strategy to alleviate oxidative impairment of vascular function
JP5102434B2 (ja) * 2002-09-09 2012-12-19 ネステク ソシエテ アノニム 皮膚品質を改良するための経口投与可能な組成物
DE10300222A1 (de) * 2003-01-03 2004-07-15 MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen
AU2004227915A1 (en) 2003-03-31 2004-10-21 John F. Engelhardt Pharmico-gene theraphy of epithelial sodium channel associated disoders
WO2005023274A1 (en) * 2003-09-05 2005-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium
US7200207B2 (en) * 2004-03-13 2007-04-03 Intrado Inc. Communication network for providing emergency services
CA2578748C (en) * 2004-09-03 2014-10-14 Kyowa Hakko Kogyo Co., Ltd. Composition and method for prevention or treatment of stomatitis
AR057623A1 (es) 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd Materiales y metodos para el tratamiento de las infecciones virales
JP2009535034A (ja) * 2006-04-28 2009-10-01 ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン 哺乳動物細胞のパルボウイルス形質導入を調節若しくはウイルス感染を変えるための方法および化合物、ウイルス受容体若しくは共受容体の同定方法
US20080057111A1 (en) * 2006-08-29 2008-03-06 Lixian Jiang Herbal composition for flu prevention and treatment
US20100151042A1 (en) * 2007-05-25 2010-06-17 Hao Yi Liang Materials and Methods for Treating Influenza Infections
EP3656385A1 (de) 2008-05-28 2020-05-27 ReveraGen BioPharma, Inc. Nichthormonale steroide modulatoren von nf-kb zur behandlung von erkrankungen
WO2011127048A2 (en) 2010-04-05 2011-10-13 Validus Biopharma NON-HORMONAL STEROID MODULATORS OF NF-ĸB FOR TREATMENT OF DISEASE
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
WO2017040370A1 (en) * 2015-09-03 2017-03-09 The Scripps Research Institute Small-molecule inhibitors of hiv-1 replication
WO2017139381A1 (en) 2016-02-08 2017-08-17 University Of Iowa Research Foundation Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
US11684679B2 (en) 2016-03-07 2023-06-27 University Of Iowa Research Foundation AAV-mediated expression using a synthetic promoter and enhancer
WO2018132747A1 (en) 2017-01-13 2018-07-19 University Of Iowa Research Foundation Bocaparvovirus small noncoding rna and uses thereof
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions
US11135220B1 (en) 2020-04-08 2021-10-05 St Ip Holding Ag Methods of treating viral infections with formulated compositions comprising 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657967A5 (en) * 1983-10-20 1986-10-15 Stronheim Bio Nutrient Foundat Nutritional adjuvant
CA1321349C (en) 1986-11-21 1993-08-17 Robert Zimmerman Therapeutic combination of free-radical scavenger or metabolic inhibitor and biologically active protein
DE3851152T2 (de) 1987-09-03 1995-01-26 Univ Georgia Cyclosporin-augenmittel.
US5026688A (en) * 1988-10-31 1991-06-25 Administrators Of The Tulane Educational Fund Novel AZT analogs
US5292773A (en) * 1990-02-14 1994-03-08 Hirsch Gerald P Treating aids and HIV infection with methionine
WO1991016034A1 (en) 1990-04-26 1991-10-31 The Procter & Gamble Company Chelator compositions comprising oxime compounds
US5977073A (en) 1991-06-06 1999-11-02 Life Sciences' Technologies, Inc. Nutrient composition for treatment of immune disorders
US5296466A (en) * 1992-02-19 1994-03-22 Board Of Regents, The University Of Texas System Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein
US5292538A (en) 1992-07-22 1994-03-08 Metagenics, Inc. Improved sustained energy and anabolic composition and method of making
US5403834A (en) * 1992-12-07 1995-04-04 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
FR2699821A1 (fr) 1992-12-24 1994-07-01 Pichot Eric Traitement homéopathique préventif des maladies cardio-vasculaires (athérome, athérothrombomatose, infarctus du myocarde).
US5824664A (en) * 1993-03-26 1998-10-20 U.S. Bioscience, Inc. Suppression of HIV expression by organic thiophosphate
US5463063A (en) * 1993-07-02 1995-10-31 Celgene Corporation Ring closure of N-phthaloylglutamines
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen

Also Published As

Publication number Publication date
ES2243941T3 (es) 2005-12-01
CA2201774A1 (en) 1996-04-11
EP0784471A2 (de) 1997-07-23
PT784471E (pt) 2005-10-31
US6514955B1 (en) 2003-02-04
AU699871B2 (en) 1998-12-17
DE69534264T2 (de) 2006-05-04
AU3760395A (en) 1996-04-26
US5846961A (en) 1998-12-08
CA2201774C (en) 2010-03-23
WO1996010402A1 (en) 1996-04-11
EP0784471B1 (de) 2005-06-08
ATE297200T1 (de) 2005-06-15
EP0784471A4 (de) 1997-11-19
US5686436A (en) 1997-11-11

Similar Documents

Publication Publication Date Title
DE69534264D1 (de) Facettenreiches verfahren zur unterdrückung der vermehrung latenter viren in menschen und tieren
EA199800667A1 (ru) Новые фенантридины
PT758248E (pt) Formulacoes para o factor ix
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
BR9609537A (pt) Composições farmacêuticas
MX9304756A (es) 9-[(glicilo substituido)amido]-6-desmetil-6-desoxitetraciclinas, metodo para su produccion y composiciones farmaceuticas que las contienen.
TR199901191T2 (xx) Benzamidoaldehitlerin sistein proteaz� inhibit�r� olarak kullan�m�.
DE69907945D1 (de) Zusammensetzung zur vorbeugung und/oder behandlung der atherosklerose
BR9811099A (pt) Inibidores de urocinase
EP0793660A4 (de) 2-substituierte 1,2,5-thiadiazolidin-3-on-1,1-dioxiden, zusammensetzung und deren verwendung
DK0623121T3 (da) Fremstilling af N-acetylneuraminsyrederivater
DE59507755D1 (de) Dipeptidische p-amidinobenzylamide mit n-terminalen sulfonyl- bzw. aminosulfonylresten
MX9704034A (es) Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso.
DK0840792T3 (da) (S)-hydroxynitrillyase fra Hevea brasiliensis
ES8100800A1 (es) Procedimiento para la preparacion de derivados furanonicos
MD960168A (ro) Metodă şi compuşi pentru tratamentul infecţiilor virale
EP0607777A3 (de)
ES2110258T3 (es) Derivados de 1,3,5(10)-estratrieno activos por via oral.
KR970061248A (ko) 알츠하이머병 치료용 1, 1, 2-트리페닐부트-1-엔 유도체
PT1150703E (pt) Terapia de esclerose multipla com chaperonina 10 e beta-interferao
EA200000112A1 (ru) Новая композиция
NO973366L (no) Fremgangsmåte for behandling av multippel sklerose
SE9402241D0 (sv) Inhibitor
MX9704035A (es) 1,1-dioxidos de 2-(fosfiniloximetil)-1,2,5-tiadiazolidin-3-ona substituidos y composiciones y metodo de uso de los mismos.
ATE255594T1 (de) Hepatitis b inhibitoren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition