ATE255594T1 - Hepatitis b inhibitoren - Google Patents

Hepatitis b inhibitoren

Info

Publication number
ATE255594T1
ATE255594T1 AT97946476T AT97946476T ATE255594T1 AT E255594 T1 ATE255594 T1 AT E255594T1 AT 97946476 T AT97946476 T AT 97946476T AT 97946476 T AT97946476 T AT 97946476T AT E255594 T1 ATE255594 T1 AT E255594T1
Authority
AT
Austria
Prior art keywords
hepatitis
inhibitors
peptides
virus
inhibit
Prior art date
Application number
AT97946476T
Other languages
English (en)
Inventor
Kenneth Murray
Michael Richard Dyson
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of ATE255594T1 publication Critical patent/ATE255594T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT97946476T 1996-10-31 1997-10-31 Hepatitis b inhibitoren ATE255594T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3053496P 1996-10-31 1996-10-31
PCT/US1997/019965 WO1998018818A2 (en) 1996-10-31 1997-10-31 Hepatitis b inhibitors

Publications (1)

Publication Number Publication Date
ATE255594T1 true ATE255594T1 (de) 2003-12-15

Family

ID=21854673

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97946476T ATE255594T1 (de) 1996-10-31 1997-10-31 Hepatitis b inhibitoren

Country Status (11)

Country Link
US (1) US6544520B1 (de)
EP (1) EP0952982B1 (de)
JP (2) JP4091663B2 (de)
AT (1) ATE255594T1 (de)
AU (1) AU5163598A (de)
CA (1) CA2270401A1 (de)
DE (1) DE69726602T2 (de)
DK (1) DK0952982T3 (de)
ES (1) ES2207753T3 (de)
PT (1) PT952982E (de)
WO (1) WO1998018818A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL348766A1 (en) 1998-12-04 2002-06-03 Biogen Hbv core antigen particles with multiple immunogenic components attached via peptide ligands
KR100746991B1 (ko) 2004-08-06 2007-08-08 한국과학기술연구원 Hbv 코아 단백질과 표면 단백질 간 상호작용의 측정을이용한 hbv의 증식 억제물질의 검색방법
KR100949310B1 (ko) * 2007-11-21 2010-03-23 한국과학기술연구원 세포 영상 기법을 이용한 hbv 캡시드 단백질과 표면단백질 간 상호작용 측정 방법과 이를 이용한 hbv 증식억제물질의 검색방법
CN101503461B (zh) * 2009-02-12 2011-09-07 北京大学人民医院 一种具有诱导肝癌细胞凋亡功能的多肽

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204096A (en) 1984-03-07 1993-04-20 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers
US5296572A (en) 1986-04-30 1994-03-22 James Sparrow Large pore polyamide resin and method of preparation thereof
CA1338800C (en) 1986-06-17 1996-12-17 Michael Houghton Hepatitis delta and diagnostics and vaccines
JPH02273700A (ja) 1989-04-14 1990-11-08 Olympus Optical Co Ltd ペプチド
US5547669A (en) 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
KR940000755B1 (ko) 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5556744A (en) 1992-05-29 1996-09-17 The Trustees Of The University Of Pennsylvania Methods and compositions for diagnosing and treating certain HIV infected patients
US5531990A (en) 1993-12-15 1996-07-02 Health Research, Inc. Method of raising an immune response with an anti-idiotypic antibody having correspondence with human hepatitis B surface antigen
US5856459A (en) 1995-06-06 1999-01-05 Hybridon, Inc. Oligonucleotides specific for hepatitis B virus

Also Published As

Publication number Publication date
JP4091663B2 (ja) 2008-05-28
ES2207753T3 (es) 2004-06-01
JP2008120814A (ja) 2008-05-29
US6544520B1 (en) 2003-04-08
JP2001503750A (ja) 2001-03-21
CA2270401A1 (en) 1998-05-07
WO1998018818A2 (en) 1998-05-07
EP0952982A2 (de) 1999-11-03
DE69726602T2 (de) 2004-09-30
EP0952982B1 (de) 2003-12-03
AU5163598A (en) 1998-05-22
DE69726602D1 (en) 2004-01-15
DK0952982T3 (da) 2004-03-29
PT952982E (pt) 2004-03-31
WO1998018818A3 (en) 1998-07-09

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