ATE165360T1 - Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung - Google Patents

Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung

Info

Publication number
ATE165360T1
ATE165360T1 AT93305864T AT93305864T ATE165360T1 AT E165360 T1 ATE165360 T1 AT E165360T1 AT 93305864 T AT93305864 T AT 93305864T AT 93305864 T AT93305864 T AT 93305864T AT E165360 T1 ATE165360 T1 AT E165360T1
Authority
AT
Austria
Prior art keywords
crystalline hydrate
hydrochloride
triazolylthiomethylthiocephalosporine
preparation
useful
Prior art date
Application number
AT93305864T
Other languages
German (de)
English (en)
Inventor
Hisanori Takahashi
Yutaka Ide
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE165360T1 publication Critical patent/ATE165360T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93305864T 1992-07-31 1993-07-26 Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung ATE165360T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20496592 1992-07-31

Publications (1)

Publication Number Publication Date
ATE165360T1 true ATE165360T1 (de) 1998-05-15

Family

ID=16499234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93305864T ATE165360T1 (de) 1992-07-31 1993-07-26 Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung

Country Status (23)

Country Link
US (1) US5407929A (cg-RX-API-DMAC7.html)
EP (1) EP0581552B1 (cg-RX-API-DMAC7.html)
KR (1) KR100245938B1 (cg-RX-API-DMAC7.html)
CN (1) CN1037683C (cg-RX-API-DMAC7.html)
AT (1) ATE165360T1 (cg-RX-API-DMAC7.html)
AU (1) AU657866B2 (cg-RX-API-DMAC7.html)
BR (1) BR9303235A (cg-RX-API-DMAC7.html)
CA (1) CA2101502A1 (cg-RX-API-DMAC7.html)
DE (1) DE69318077T2 (cg-RX-API-DMAC7.html)
ES (1) ES2115725T3 (cg-RX-API-DMAC7.html)
FI (1) FI933391A7 (cg-RX-API-DMAC7.html)
GR (1) GR3026699T3 (cg-RX-API-DMAC7.html)
HU (1) HU219637B (cg-RX-API-DMAC7.html)
IL (1) IL106516A (cg-RX-API-DMAC7.html)
MX (1) MX9304611A (cg-RX-API-DMAC7.html)
NO (1) NO303734B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ248285A (cg-RX-API-DMAC7.html)
PH (1) PH30109A (cg-RX-API-DMAC7.html)
PL (2) PL172830B1 (cg-RX-API-DMAC7.html)
RU (1) RU2118959C1 (cg-RX-API-DMAC7.html)
TW (1) TW307769B (cg-RX-API-DMAC7.html)
UA (1) UA37181C2 (cg-RX-API-DMAC7.html)
ZA (1) ZA935529B (cg-RX-API-DMAC7.html)

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MXPA03007349A (es) * 2001-02-24 2003-12-04 Boehringer Ingelheim Pharma Derivados de xantina, su preparacion y su empleo como medicamentos.
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
KR20030076759A (ko) * 2002-03-21 2003-09-29 주식회사 엘지생명과학 신규 세팔로스포린 화합물 및 그의 제조 방법
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
CN101219992B (zh) 2003-02-12 2011-08-31 日产化学工业株式会社 匹伐他汀钙的晶形
BRPI0408716B1 (pt) 2003-03-27 2017-08-29 Basilea Pharmaceutica Ag. Cefalosporin in crystalline form, process for its preparation and its uses, and preparation of cephalosporin
US7501426B2 (en) * 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) * 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20080251A1 (es) * 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
NZ600394A (en) 2006-05-04 2014-04-30 Boehringer Ingelheim Int Polymorphs of a dpp-iv enzyme inhibitor
ES2733348T3 (es) * 2007-08-17 2019-11-28 Boehringer Ingelheim Int Derivados de purina para uso en el tratamiento de enfermedades relacionadas con FAP
AR071175A1 (es) 2008-04-03 2010-06-02 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
CA2735562C (en) * 2008-08-15 2017-10-17 Boehringer Ingelheim International Gmbh Dpp-4 inhibitors for wound healing
MX2011002558A (es) 2008-09-10 2011-04-26 Boehringer Ingelheim Int Terapia de combinacion para el tratamiento de diabetes y estados relacionados.
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CA2745037C (en) 2008-12-23 2020-06-23 Boehringer Ingelheim International Gmbh Salt forms of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8(3-(r)-amino-piperidin-1-yl)-xanthine
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
CN102753161A (zh) 2009-11-27 2012-10-24 贝林格尔.英格海姆国际有限公司 基因型糖尿病患者利用dpp-iv抑制剂例如利拉利汀的治疗
CN107961377B (zh) 2010-05-05 2022-11-22 勃林格殷格翰国际有限公司 组合疗法
MX2012014247A (es) 2010-06-24 2013-01-18 Boehringer Ingelheim Int Terapia para la diabetes.
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
PL2731947T3 (pl) 2011-07-15 2019-07-31 Boehringer Ingelheim International Gmbh Podstawiona dimeryczna pochodna chinazoliny, sposób jej wytwarzania i jej zastosowanie w kompozycjach farmaceutycznych do leczenia cukrzycy typu I i II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US20130303462A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
US20130303554A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in sirs and/or sepsis
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
WO2015128453A1 (en) 2014-02-28 2015-09-03 Boehringer Ingelheim International Gmbh Medical use of a dpp-4 inhibitor
CA3022202A1 (en) 2016-06-10 2017-12-14 Boehringer Ingelheim International Gmbh Combinations of linagliptin and metformin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
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ES475573A1 (es) * 1977-07-12 1980-01-16 Fujisawa Pharmaceutical Co Un procedimiento para preparar nuevos compuestos de cefem
IE65926B1 (en) * 1990-07-19 1995-11-29 Shionogi & Co Thioalkylthio cephalosporin derivatives

Also Published As

Publication number Publication date
MX9304611A (es) 1994-02-28
CN1037683C (zh) 1998-03-11
FI933391L (fi) 1994-02-01
KR100245938B1 (ko) 2000-04-01
CA2101502A1 (en) 1994-02-01
DE69318077T2 (de) 1998-10-29
HUT68602A (en) 1995-06-28
EP0581552A2 (en) 1994-02-02
CN1089948A (zh) 1994-07-27
PL172830B1 (pl) 1997-12-31
EP0581552B1 (en) 1998-04-22
IL106516A0 (en) 1993-11-15
ZA935529B (en) 1994-02-24
PL299870A1 (en) 1994-02-07
DE69318077D1 (de) 1998-05-28
FI933391A7 (fi) 1994-02-01
ES2115725T3 (es) 1998-07-01
AU657866B2 (en) 1995-03-23
PH30109A (en) 1996-12-27
TW307769B (cg-RX-API-DMAC7.html) 1997-06-11
UA37181C2 (uk) 2001-05-15
NZ248285A (en) 1994-07-26
NO932745D0 (no) 1993-07-30
AU4422793A (en) 1994-02-03
FI933391A0 (fi) 1993-07-29
IL106516A (en) 1998-06-15
US5407929A (en) 1995-04-18
RU2118959C1 (ru) 1998-09-20
HU9302194D0 (en) 1993-10-28
NO303734B1 (no) 1998-08-24
NO932745L (no) 1994-02-01
KR940005636A (ko) 1994-03-22
EP0581552A3 (en) 1994-06-01
HU219637B (hu) 2001-06-28
PL172835B1 (pl) 1997-12-31
GR3026699T3 (en) 1998-07-31
BR9303235A (pt) 1994-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee