ATE161265T1 - Derivate von 16-gliedrigen antibiotischen macroliden - Google Patents

Derivate von 16-gliedrigen antibiotischen macroliden

Info

Publication number
ATE161265T1
ATE161265T1 AT93914300T AT93914300T ATE161265T1 AT E161265 T1 ATE161265 T1 AT E161265T1 AT 93914300 T AT93914300 T AT 93914300T AT 93914300 T AT93914300 T AT 93914300T AT E161265 T1 ATE161265 T1 AT E161265T1
Authority
AT
Austria
Prior art keywords
pct
derivatives
macrolids
antibiotic
animals
Prior art date
Application number
AT93914300T
Other languages
English (en)
Inventor
Scott J Hecker
Martin R Jefson
James W Mcfarland
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE161265T1 publication Critical patent/ATE161265T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT93914300T 1992-07-15 1993-06-07 Derivate von 16-gliedrigen antibiotischen macroliden ATE161265T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91424292A 1992-07-15 1992-07-15
US99624392A 1992-12-23 1992-12-23

Publications (1)

Publication Number Publication Date
ATE161265T1 true ATE161265T1 (de) 1998-01-15

Family

ID=27129638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93914300T ATE161265T1 (de) 1992-07-15 1993-06-07 Derivate von 16-gliedrigen antibiotischen macroliden

Country Status (22)

Country Link
US (1) US5545624A (de)
EP (1) EP0649430B1 (de)
JP (1) JP2836964B2 (de)
KR (1) KR950702570A (de)
CN (1) CN1083068A (de)
AT (1) ATE161265T1 (de)
AU (1) AU4401093A (de)
BR (1) BR9306741A (de)
CA (1) CA2140243A1 (de)
CZ (1) CZ9995A3 (de)
DE (1) DE69315839T2 (de)
DK (1) DK0649430T3 (de)
FI (1) FI933204A (de)
GR (1) GR3026064T3 (de)
HU (1) HUT65330A (de)
IL (1) IL106263A0 (de)
MX (1) MX9304301A (de)
PL (1) PL307137A1 (de)
SK (1) SK4795A3 (de)
TW (1) TW226373B (de)
UY (1) UY23617A1 (de)
WO (1) WO1994002496A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677287A (en) * 1993-03-18 1997-10-14 Pfizer Inc. Antibacterial 16-membered ring macrolides containing olefins at C-20
ATE151767T1 (de) * 1993-07-15 1997-05-15 Pfizer Amid-derivate von 16-gliedrige heterocyclen als antibiotische macrolide
ES2076107B1 (es) * 1993-09-20 1996-04-01 Pfizer Derivados de antibioticos macrolidos de anillos de 16 miembros.
AU3121095A (en) * 1994-09-22 1996-04-09 Pfizer Inc. Antibiotic macrolides
EP0778283A3 (de) * 1995-12-05 1998-01-28 Pfizer Inc. Antibiotische Makrolide
US6605599B1 (en) * 1997-07-08 2003-08-12 Bristol-Myers Squibb Company Epothilone derivatives
CA2391834C (en) * 1999-08-30 2008-08-05 Toshiaki Miyake Macrolide antibiotics and treatment of pasteurellosis
US20020111317A1 (en) * 2000-09-25 2002-08-15 Leonard Katz Sixteen-membered macrolide compounds
US6664240B2 (en) 2001-11-15 2003-12-16 Enanta Pharmaceuticals, Inc. Tylosin derivatives having antibacterial activity
WO2003078411A1 (en) 2002-03-12 2003-09-25 Bristol-Myers Squibb Company C3-cyano epothilone derivatives
US7247617B2 (en) * 2004-07-13 2007-07-24 Kosan Biosciences Incorporated Sixteen-member macrolide antiinfective agents
JP5323696B2 (ja) 2006-07-28 2013-10-23 インターベツト・インターナシヨナル・ベー・ベー マクロライド合成方法
CN101506220B (zh) * 2006-07-28 2012-10-17 英特威国际有限公司 大环内酯合成方法
BR112014012585B1 (pt) 2011-11-25 2021-05-25 Bayer Intellectual Property Gmbh composto compreendendo derivados de tilosina, método de preparo do mesmo e composição farmacêutica ou veterinária
FR2995605B1 (fr) * 2012-09-18 2014-09-19 Sanofi Sa Derives de macrolides, leur preparation et leur application therapeutique.
NO2999707T3 (de) * 2013-05-23 2018-08-25
CN104788519B (zh) * 2014-01-22 2018-07-20 镇江威特药业有限责任公司 十六元环三胺内酯衍生物及其应用
CN105777828A (zh) * 2014-12-22 2016-07-20 菏泽市方明制药有限公司 一种用低质量的泰乐菌素制备高质量替米考星的方法
US10287275B2 (en) 2015-04-16 2019-05-14 Victor Pharma Co., Ltd. Zhenjiang 16-member triamilide derivatives and uses thereof
CN117510561B (zh) * 2023-11-30 2024-04-02 中国农业科学院饲料研究所 一种泰乐菌素衍生物及其制备方法与应用
CN117304241B (zh) * 2023-11-30 2024-03-01 中国农业科学院饲料研究所 一种大环内酯类化合物及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975372A (en) * 1975-02-28 1976-08-17 Schering Corporation Preparation of 12,13-desepoxy-12,13-dehydrorosamicin
AU561147B2 (en) * 1982-09-13 1987-04-30 Eli Lilly And Company 20-amino macrolide antibiotics
US4443436A (en) * 1982-09-13 1984-04-17 Eli Lilly And Company C-20-Modified macrolide derivatives of the macrolide antibiotics tylosin, desmycosin, macrocin, and lactenocin
JPS59225199A (ja) * 1983-02-10 1984-12-18 Microbial Chem Res Found ２０，２３−ジデオキシ−２３−アルキレンイミノ−２０−置換アミノマイカミノシルレロノライド
IL71032A0 (en) * 1983-02-28 1984-05-31 Lilly Co Eli C-20 and c-23-modified macrolide derivatives
US4468511A (en) * 1983-02-28 1984-08-28 Eli Lilly And Company C-20- And C-23-Modified macrolide derivatives
JPS59181299A (ja) * 1983-03-31 1984-10-15 Microbial Chem Res Found ２０，２３−ジデオキシ−２０，２３−ビス置換アミノ−マイカミノシルレロノライド
US4921947A (en) * 1986-03-31 1990-05-01 Eli Lilly And Company Process for preparing macrolide derivatives
EP0262903A3 (de) * 1986-09-29 1988-11-02 Eli Lilly And Company Acylderivate von 20-modifiziertem Tylosin und Desmycosin-Derivate
US4820694A (en) * 1986-09-29 1989-04-11 Eli Lilly And Company Modifications of 3-O-demethylmycinose in macrocin and lactenocin
US4920103A (en) * 1986-09-29 1990-04-24 Eli Lilly And Company Modifications of mycinose and 3-O-demethylmycinose in tylosin-type macrolides
FR2638458A1 (fr) * 1988-10-27 1990-05-04 Adir Nouveaux derives de la tylosine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
CZ9995A3 (en) 1995-07-12
TW226373B (de) 1994-07-11
PL307137A1 (en) 1995-05-02
FI933204A0 (fi) 1993-07-14
CA2140243A1 (en) 1994-02-03
UY23617A1 (es) 1994-01-05
BR9306741A (pt) 1998-12-08
EP0649430A1 (de) 1995-04-26
SK4795A3 (en) 1995-07-11
MX9304301A (es) 1994-02-28
US5545624A (en) 1996-08-13
HU9302016D0 (en) 1993-10-28
GR3026064T3 (en) 1998-05-29
AU4401093A (en) 1994-02-14
DK0649430T3 (da) 1998-02-09
WO1994002496A1 (en) 1994-02-03
JP2836964B2 (ja) 1998-12-14
DE69315839T2 (de) 1998-04-09
KR950702570A (ko) 1995-07-29
IL106263A0 (en) 1993-11-15
EP0649430B1 (de) 1997-12-17
CN1083068A (zh) 1994-03-02
DE69315839D1 (de) 1998-01-29
JPH07504922A (ja) 1995-06-01
HUT65330A (en) 1994-05-02
FI933204A (fi) 1994-01-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee