ATE156842T1 - Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen - Google Patents

Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Info

Publication number
ATE156842T1
ATE156842T1 AT94904168T AT94904168T ATE156842T1 AT E156842 T1 ATE156842 T1 AT E156842T1 AT 94904168 T AT94904168 T AT 94904168T AT 94904168 T AT94904168 T AT 94904168T AT E156842 T1 ATE156842 T1 AT E156842T1
Authority
AT
Austria
Prior art keywords
pct
molecular weight
glycosaminoglycans
oligosaccharides
producing
Prior art date
Application number
AT94904168T
Other languages
English (en)
Inventor
Gianni Ferrari
Original Assignee
Mediolanum Farmaceutici Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici Srl filed Critical Mediolanum Farmaceutici Srl
Application granted granted Critical
Publication of ATE156842T1 publication Critical patent/ATE156842T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT94904168T 1992-12-23 1993-12-21 Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen ATE156842T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922950A IT1256236B (it) 1992-12-23 1992-12-23 Oligosaccaridi aventi attivita' biologica e procedimento per la loro preparazione di glicosaminoglicani

Publications (1)

Publication Number Publication Date
ATE156842T1 true ATE156842T1 (de) 1997-08-15

Family

ID=11364528

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94904168T ATE156842T1 (de) 1992-12-23 1993-12-21 Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Country Status (9)

Country Link
US (1) US5705493A (de)
EP (1) EP0675905B1 (de)
AT (1) ATE156842T1 (de)
AU (1) AU5833694A (de)
CA (1) CA2151610A1 (de)
DE (1) DE69313138T2 (de)
ES (1) ES2108418T3 (de)
IT (1) IT1256236B (de)
WO (1) WO1994014850A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004059506A (ja) * 2002-07-29 2004-02-26 Taisho Pharmaceut Co Ltd セレクチン及びケモカインに作用する過硫酸化オリゴ糖
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US8021677B2 (en) 2006-05-12 2011-09-20 Gore Enterprise Holdings, Inc. Immobilized biologically active entities having a high degree of biological activity
US20150011501A1 (en) * 2012-02-17 2015-01-08 Kimflexor, S.L. Partially depolymerized glycosaminoglycan silver and gold salts
CN114057908A (zh) * 2020-08-08 2022-02-18 烟台东诚药业集团股份有限公司 一种低分子硫酸软骨素钠的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454560A (en) * 1966-03-01 1969-07-08 Seikagaku Kogyo Co Ltd Process for the production of chondroitin polysulfate
JPS4942486B1 (de) * 1970-09-21 1974-11-15
FR2482611B1 (fr) * 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2548672A1 (fr) * 1983-07-04 1985-01-11 Pharmuka Lab Oligosaccharides sulfates et leur utilisation comme medicaments
IT1208509B (it) * 1985-03-13 1989-07-10 Mediolanum Farmaceutici Srl Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1245761B (it) * 1991-01-30 1994-10-14 Alfa Wassermann Spa Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.

Also Published As

Publication number Publication date
WO1994014850A1 (en) 1994-07-07
ITMI922950A1 (it) 1994-06-23
EP0675905A1 (de) 1995-10-11
EP0675905B1 (de) 1997-08-13
DE69313138D1 (de) 1997-09-18
IT1256236B (it) 1995-11-29
ES2108418T3 (es) 1997-12-16
AU5833694A (en) 1994-07-19
ITMI922950A0 (it) 1992-12-23
DE69313138T2 (de) 1997-12-11
US5705493A (en) 1998-01-06
CA2151610A1 (en) 1994-07-07

Similar Documents

Publication Publication Date Title
DE69023957T2 (de) Sulfatierte Polysaccharide, Antikoagulierungs- und Antikomplementärmittel, hergestellt aus Fukanen aus braunen Algen, und Verfahren zu deren Herstellung.
CA2325046A1 (en) Lactic acid residue containing polymer composition and product having improved stability, and method for preparation and use thereof
ES2269943T5 (es) Polímeros solubles de glucosa altamente ramificados y su procedimiento de obtención
ATE66350T1 (de) Suessware und verfahren zur herstellung derselben.
DE69433177D1 (de) Kulturmedium und verfahren zur herstellung von hyaluronsäure mit hohem molekulargewicht
DE60013271D1 (de) Verfahren zur herstellung von verzweigten, löslichen glukose-polymerisaten
SE8900586L (sv) Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader
SE9504495L (sv) Linjär blockpolymer innefattande urea- och uretangrupper, förfarande för framställning av linjära blockpolymerer samt användning av blockpolymererna som implantat
DE69308143D1 (de) Verfahren zur herstellung von polymilchsäure
ES2193144T3 (es) Compuestos de dna que comprenden secuencias que codifican manuronano c-5-epimerasa.
EP0126523A3 (en) Dentifrice compostions
DE69305346T2 (de) Zusammensetzung zur kontrollierten abgabe eines wirkstoffes und verfahren zur herstellung derselben
ATE157879T1 (de) Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungen
ATE123069T1 (de) Verfahren zur herstellung von humanem faktor viii und dessen analogen.
BG103822A (en) The use of zinc hyaluronate against peptic ulcer
ATE156842T1 (de) Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen
DE59503194D1 (de) Verfahren zur herstellung von stärkeabbauprodukten
CA2131565A1 (en) Organopolysiloxanes Containing Hydrophilic Groups
EP0477050A3 (en) Lps-producing bacteria, lpss, and lps-containing medicines and veterinary medicines
DE69018440D1 (de) Verfahren zur herstellung von hyaluronsäure mit niedrigem molekulargewicht.
EP0475383A3 (en) Polysaccharide composition or polysaccharide having heparinoid activity, process for producing the same, and anticoagulant containing the same as active ingredient
AU8595791A (en) Galactomannan derivatives for coating or embedding medicinally active substances
EP0786524A3 (de) Neue verzweigte Cyclodextrine und Verfahren zu ihrer Herstellung
ATE170403T1 (de) Alginatwundverbände
ATE135703T1 (de) Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties