DE69313138D1 - Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen - Google Patents

Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Info

Publication number
DE69313138D1
DE69313138D1 DE69313138T DE69313138T DE69313138D1 DE 69313138 D1 DE69313138 D1 DE 69313138D1 DE 69313138 T DE69313138 T DE 69313138T DE 69313138 T DE69313138 T DE 69313138T DE 69313138 D1 DE69313138 D1 DE 69313138D1
Authority
DE
Germany
Prior art keywords
pct
molecular weight
glycosaminoglycans
oligosaccharides
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69313138T
Other languages
English (en)
Other versions
DE69313138T2 (de
Inventor
Gianni Ferrari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediolanum Farmaceutici SpA
Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici SpA filed Critical Mediolanum Farmaceutici SpA
Application granted granted Critical
Publication of DE69313138D1 publication Critical patent/DE69313138D1/de
Publication of DE69313138T2 publication Critical patent/DE69313138T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69313138T 1992-12-23 1993-12-21 Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen Expired - Fee Related DE69313138T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922950A IT1256236B (it) 1992-12-23 1992-12-23 Oligosaccaridi aventi attivita' biologica e procedimento per la loro preparazione di glicosaminoglicani
PCT/EP1993/003646 WO1994014850A1 (en) 1992-12-23 1993-12-21 Oligosaccharides having biological activity and preparation of same from glycosaminoglycans

Publications (2)

Publication Number Publication Date
DE69313138D1 true DE69313138D1 (de) 1997-09-18
DE69313138T2 DE69313138T2 (de) 1997-12-11

Family

ID=11364528

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69313138T Expired - Fee Related DE69313138T2 (de) 1992-12-23 1993-12-21 Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Country Status (9)

Country Link
US (1) US5705493A (de)
EP (1) EP0675905B1 (de)
AT (1) ATE156842T1 (de)
AU (1) AU5833694A (de)
CA (1) CA2151610A1 (de)
DE (1) DE69313138T2 (de)
ES (1) ES2108418T3 (de)
IT (1) IT1256236B (de)
WO (1) WO1994014850A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004059506A (ja) * 2002-07-29 2004-02-26 Taisho Pharmaceut Co Ltd セレクチン及びケモカインに作用する過硫酸化オリゴ糖
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US8021677B2 (en) 2006-05-12 2011-09-20 Gore Enterprise Holdings, Inc. Immobilized biologically active entities having a high degree of biological activity
CA2861052A1 (en) * 2012-02-17 2013-08-22 Kimflexor, S.L. Partially depolymerized glycosaminoglycan silver and gold salts
CN114057908A (zh) * 2020-08-08 2022-02-18 烟台东诚药业集团股份有限公司 一种低分子硫酸软骨素钠的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454560A (en) * 1966-03-01 1969-07-08 Seikagaku Kogyo Co Ltd Process for the production of chondroitin polysulfate
JPS4942486B1 (de) * 1970-09-21 1974-11-15
FR2482611B1 (fr) * 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2548672A1 (fr) * 1983-07-04 1985-01-11 Pharmuka Lab Oligosaccharides sulfates et leur utilisation comme medicaments
IT1208509B (it) * 1985-03-13 1989-07-10 Mediolanum Farmaceutici Srl Processo per la produzione di eparan solfato e dermatan solfato naturali sostanzialmente puri eloro impiego farmaceutico.
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1245761B (it) * 1991-01-30 1994-10-14 Alfa Wassermann Spa Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale.

Also Published As

Publication number Publication date
IT1256236B (it) 1995-11-29
EP0675905B1 (de) 1997-08-13
DE69313138T2 (de) 1997-12-11
AU5833694A (en) 1994-07-19
US5705493A (en) 1998-01-06
ITMI922950A1 (it) 1994-06-23
ITMI922950A0 (it) 1992-12-23
CA2151610A1 (en) 1994-07-07
ATE156842T1 (de) 1997-08-15
EP0675905A1 (de) 1995-10-11
WO1994014850A1 (en) 1994-07-07
ES2108418T3 (es) 1997-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee