CA1323293C
(en)
*
|
1987-12-11 |
1993-10-19 |
Keith C. Backman |
Assay using template-dependent nucleic acid probe reorganization
|
US5449602A
(en)
*
|
1988-01-13 |
1995-09-12 |
Amoco Corporation |
Template-directed photoligation
|
DE68927373T2
(de)
*
|
1988-06-24 |
1997-03-20 |
Amgen Inc., Thousand Oaks, Calif. |
Verfahren und mittel zum nachweis von nukleinsäuresequenzen
|
US5175273A
(en)
*
|
1988-07-01 |
1992-12-29 |
Genentech, Inc. |
Nucleic acid intercalating agents
|
US6004826A
(en)
*
|
1988-07-20 |
1999-12-21 |
David Segev |
Repair-mediated process for amplifying and detecting nucleic acid sequences
|
WO1990001069A1
(en)
*
|
1988-07-20 |
1990-02-08 |
Segev Diagnostics, Inc. |
Process for amplifying and detecting nucleic acid sequences
|
GR1000347B
(el)
*
|
1988-12-21 |
1992-06-25 |
Ortho Diagnostic Systems Inc |
Μεθοδος παραγωγης νουκλεοτιδικων ανιχνευτων χρησιμοποιωντας ενα συμπληρωμα γεφυρωσεως.
|
EP0431086B1
(de)
*
|
1989-04-05 |
1997-05-28 |
VYSIS, Inc. |
Reagenzien zur verbesserung von hybridisierung
|
US5650302A
(en)
*
|
1990-05-01 |
1997-07-22 |
Amgen Inc. |
Method for reducing carryover contamination in an amplification procedure
|
US5494810A
(en)
*
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
US6277570B1
(en)
|
1993-04-13 |
2001-08-21 |
Naxcor |
Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
|
DE69429338T2
(de)
*
|
1993-04-13 |
2002-08-14 |
Naxcor, Menlo Park |
Nicht-nucleosidische cumarin-derivate als reagenzien zum crosslinking von polynucleotiden
|
US5767259A
(en)
*
|
1994-12-27 |
1998-06-16 |
Naxcor |
Oligonucleotides containing base-free linking groups with photoactivatable side chains
|
US6495676B1
(en)
|
1993-04-13 |
2002-12-17 |
Naxcor |
Nucleic acid sequence detection employing probes comprising non-nucleosidic coumarin derivatives as polynucleotide-crosslinking agents
|
US5616464A
(en)
*
|
1994-12-27 |
1997-04-01 |
Naxcor |
Nucleic acid sequence detection employing amplification probes
|
US5846709A
(en)
*
|
1993-06-15 |
1998-12-08 |
Imclone Systems Incorporated |
Chemical process for amplifying and detecting nucleic acid sequences
|
SE9400522D0
(sv)
|
1994-02-16 |
1994-02-16 |
Ulf Landegren |
Method and reagent for detecting specific nucleotide sequences
|
US5876924A
(en)
*
|
1994-06-22 |
1999-03-02 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method hybridization signal amplification method (HSAM)
|
US6593086B2
(en)
|
1996-05-20 |
2003-07-15 |
Mount Sinai School Of Medicine Of New York University |
Nucleic acid amplification methods
|
US5942391A
(en)
*
|
1994-06-22 |
1999-08-24 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method: ramification-extension amplification method (RAM)
|
EP0717782A1
(de)
*
|
1994-06-22 |
1996-06-26 |
Mount Sinai School Of Medicine Of The City University Of New York |
Ligation-abhängige amplifizierung zum nachweis von infektösen pathogenen und anormalen genen
|
USRE38442E1
(en)
*
|
1994-06-22 |
2004-02-24 |
Mount Sinai School Of Medicine |
Nucleic acid amplification method hybridization signal amplification method (HSAM)
|
US8236493B2
(en)
|
1994-10-21 |
2012-08-07 |
Affymetrix, Inc. |
Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
|
US6974666B1
(en)
*
|
1994-10-21 |
2005-12-13 |
Appymetric, Inc. |
Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
|
SE9403805D0
(sv)
*
|
1994-11-07 |
1994-11-07 |
Ulf Landegren |
Method of preparing oligonucleotide probes or primers, vector therefor and use thereof
|
JPH11501927A
(ja)
*
|
1995-03-09 |
1999-02-16 |
ナクスコー |
ポリヌクレオチド架橋剤としての非ヌクレオシドクマリン誘導体
|
WO1996040992A2
(en)
*
|
1995-06-07 |
1996-12-19 |
Abbott Laboratories |
Probe masking method of reducing background in an amplification reaction
|
JPH11514525A
(ja)
*
|
1995-11-03 |
1999-12-14 |
ナックスコー |
二本鎖高次構造多型分析
|
JP2001514873A
(ja)
*
|
1997-08-20 |
2001-09-18 |
ソーマジェニックス インコーポレイテッド |
結合特性が改善されたアンチセンスおよびアンチジーン治療薬並びにそれらの使用方法
|
DK1075328T3
(da)
|
1998-05-01 |
2006-03-27 |
Gen Probe Inc |
Automatiseret diagnostisk analysefremgangsmåde
|
US8337753B2
(en)
|
1998-05-01 |
2012-12-25 |
Gen-Probe Incorporated |
Temperature-controlled incubator having a receptacle mixing mechanism
|
US6124099A
(en)
*
|
1998-06-22 |
2000-09-26 |
The University Of Vermont And State Agricultural College |
Method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids
|
AU5779399A
(en)
|
1998-08-21 |
2000-03-27 |
Naxcor |
Assays using crosslinkable immobilized nucleic acids
|
US6303799B1
(en)
|
1998-11-10 |
2001-10-16 |
Naxcor |
Polynucleotide crosslinking agents
|
US7014994B1
(en)
|
1999-03-19 |
2006-03-21 |
Cornell Research Foundation,Inc. |
Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
|
AU2998800A
(en)
|
1999-03-24 |
2000-10-09 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
N-acylphosphoramidites and their use in oligonucleotide synthesis
|
US6372813B1
(en)
*
|
1999-06-25 |
2002-04-16 |
Motorola |
Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays
|
US6593088B1
(en)
|
1999-08-27 |
2003-07-15 |
Japan Science And Technology Corporation |
Reversible photocoupling nucleic acid and phosphoroamidite
|
US7306904B2
(en)
*
|
2000-02-18 |
2007-12-11 |
Olink Ab |
Methods and kits for proximity probing
|
JP3753942B2
(ja)
*
|
2000-03-10 |
2006-03-08 |
独立行政法人科学技術振興機構 |
5−ピリミジン含有核酸、それを用いた可逆的連結方法
|
US20040067498A1
(en)
*
|
2000-04-28 |
2004-04-08 |
Ahmed Chenna |
Detection of nucleic acid sequences by cleavage and separation of tag-containing structures
|
US6562575B1
(en)
|
2000-06-26 |
2003-05-13 |
Epicentre Technologies Corporation |
Analyte-specific assays based on formation of a replicase substrate
|
WO2002030944A2
(en)
|
2000-10-11 |
2002-04-18 |
Applera Corporation |
Fluorescent nucleobase conjugates having anionic linkers
|
JP4128453B2
(ja)
*
|
2001-03-19 |
2008-07-30 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
新規分子機能の進化
|
EP1377686A4
(de)
*
|
2001-04-12 |
2007-07-25 |
Caliper Life Sciences Inc |
Systeme und verfahren für genetische analyse mit hohem durchsatz
|
WO2002102820A1
(en)
|
2001-06-20 |
2002-12-27 |
Nuevolution A/S |
Nucleoside derivatives for library preparation
|
CA2465588A1
(en)
*
|
2001-11-09 |
2003-05-22 |
Aclara Biosciences, Inc. |
Detection of nucleic acid sequences by cleavage and separation of tag-containing structures
|
US6589744B2
(en)
|
2001-11-26 |
2003-07-08 |
Syngenta Participations Ag |
Method and kit for identification for nucleic acid modification enzymes and inhibitors thereof
|
WO2003048179A2
(en)
*
|
2001-12-03 |
2003-06-12 |
The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services |
Thermolabile hydroxyl protecting groups and methods of use
|
ATE414769T1
(de)
|
2002-03-15 |
2008-12-15 |
Nuevolution As |
Eine verbesserte methode zur synthese von matritzenabhängigen molekülen
|
AU2003247266A1
(en)
|
2002-08-01 |
2004-02-23 |
Nuevolution A/S |
Multi-step synthesis of templated molecules
|
EP1540013B1
(de)
*
|
2002-08-19 |
2015-07-08 |
The President and Fellows of Harvard College |
Entwicklung einer neuen molekularen funktion
|
US7508608B2
(en)
|
2004-11-17 |
2009-03-24 |
Illumina, Inc. |
Lithographically fabricated holographic optical identification element
|
US7164533B2
(en)
|
2003-01-22 |
2007-01-16 |
Cyvera Corporation |
Hybrid random bead/chip based microarray
|
US7901630B2
(en)
|
2002-08-20 |
2011-03-08 |
Illumina, Inc. |
Diffraction grating-based encoded microparticle assay stick
|
US7872804B2
(en)
|
2002-08-20 |
2011-01-18 |
Illumina, Inc. |
Encoded particle having a grating with variations in the refractive index
|
US7619819B2
(en)
|
2002-08-20 |
2009-11-17 |
Illumina, Inc. |
Method and apparatus for drug product tracking using encoded optical identification elements
|
US7923260B2
(en)
|
2002-08-20 |
2011-04-12 |
Illumina, Inc. |
Method of reading encoded particles
|
US7900836B2
(en)
|
2002-08-20 |
2011-03-08 |
Illumina, Inc. |
Optical reader system for substrates having an optically readable code
|
US7092160B2
(en)
|
2002-09-12 |
2006-08-15 |
Illumina, Inc. |
Method of manufacturing of diffraction grating-based optical identification element
|
US20100255603A9
(en)
|
2002-09-12 |
2010-10-07 |
Putnam Martin A |
Method and apparatus for aligning microbeads in order to interrogate the same
|
ES2640279T3
(es)
|
2002-10-30 |
2017-11-02 |
Nuevolution A/S |
Procedimiento para la síntesis de un complejo bifuncional
|
EP1756277B1
(de)
|
2002-12-19 |
2009-12-02 |
Nuevolution A/S |
Durch quasizufallsstrukturen und funktionen geführte synthesemethode
|
US20070026397A1
(en)
|
2003-02-21 |
2007-02-01 |
Nuevolution A/S |
Method for producing second-generation library
|
EP2236606B1
(de)
|
2003-03-20 |
2013-11-06 |
Nuevolution A/S |
Ligationsvermittelnde Codierung von kleinen Molekülen
|
US8017323B2
(en)
*
|
2003-03-26 |
2011-09-13 |
President And Fellows Of Harvard College |
Free reactant use in nucleic acid-templated synthesis
|
US20090163375A1
(en)
|
2003-09-09 |
2009-06-25 |
Bowman Christopher N |
Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event
|
US7354706B2
(en)
*
|
2003-09-09 |
2008-04-08 |
The Regents Of The University Of Colorado, A Body Corporate |
Use of photopolymerization for amplification and detection of a molecular recognition event
|
ATE464399T1
(de)
*
|
2003-09-09 |
2010-04-15 |
Univ Colorado Regents |
Verwendung der photopolymerisierung zur amplifikation und zum nachweis eines molekularen erkennungsereignisses
|
EP1670939B1
(de)
|
2003-09-18 |
2009-11-04 |
Nuevolution A/S |
Methode zur Gewinnung struktureller Informationen kodierter Moleküle und zur Selektion von Verbindungen
|
US7433123B2
(en)
|
2004-02-19 |
2008-10-07 |
Illumina, Inc. |
Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
|
EP1730277B1
(de)
|
2004-03-22 |
2009-10-28 |
Nuevolution A/S |
Ligationscodierung unter verwendung von oligonukleotidbausteinen
|
US7175334B2
(en)
|
2004-03-31 |
2007-02-13 |
Dpc Cirrus, Inc. |
Vessel agitator assembly
|
US7517978B1
(en)
*
|
2004-04-14 |
2009-04-14 |
Applied Biosystems, Llc |
Modified oligonucleotides and applications thereof
|
US7408051B2
(en)
*
|
2004-04-14 |
2008-08-05 |
Applera Corporation |
Modified oligonucleotides and applications thereof
|
ATE494392T1
(de)
|
2004-09-21 |
2011-01-15 |
Life Technologies Corp |
Zweifarbige echtzeit/endpunkt-quantifizierung von mikro-rnas (mirnas)
|
CA2587674A1
(en)
|
2004-11-16 |
2006-05-26 |
Illumina, Inc. |
Method and apparatus for reading coded microbeads
|
US9809824B2
(en)
*
|
2004-12-13 |
2017-11-07 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods
|
CN101171343A
(zh)
*
|
2005-04-14 |
2008-04-30 |
阿普里拉股份有限公司 |
含有假异胞嘧啶核碱基衍生物的3’修饰寡核苷酸及其作为引物或探针的应用
|
FI119038B
(fi)
*
|
2005-05-13 |
2008-06-30 |
Luvata Oy |
Menetelmä suprajohtavan elementin valmistamiseksi
|
US20070048759A1
(en)
*
|
2005-06-10 |
2007-03-01 |
Dan Luo |
Detection of target molecules with labeled nucleic acid detection molecules
|
US20100136614A1
(en)
*
|
2005-10-18 |
2010-06-03 |
Dan Luo |
Dendrimer-like modular delivery vector
|
US20070148246A1
(en)
*
|
2005-08-11 |
2007-06-28 |
Dan Luo |
Nucleic Acid-Based Matrixes
|
US8486621B2
(en)
*
|
2005-08-11 |
2013-07-16 |
Cornell Research Foundation, Inc. |
Nucleic acid-based matrixes
|
US7851159B2
(en)
*
|
2005-11-17 |
2010-12-14 |
Japan Science And Technology Agency |
Method for detecting target nucleic acid with specific base sequence and set of nucleic acids for detection
|
EP1957644B1
(de)
|
2005-12-01 |
2010-12-01 |
Nuevolution A/S |
Enzymvermittelnde kodierungsmethoden für eine effiziente synthese von grossen bibliotheken
|
US8153361B1
(en)
*
|
2006-02-06 |
2012-04-10 |
Steven Albert Benner |
Dynamic and combinatorial synthesis of polymerase primers
|
US7830575B2
(en)
|
2006-04-10 |
2010-11-09 |
Illumina, Inc. |
Optical scanner with improved scan time
|
US20090036325A1
(en)
*
|
2007-05-25 |
2009-02-05 |
Applera Corporation |
Directed assembly of amplicons to enhance read pairing signature with massively parallel short read sequencers
|
US20090137405A1
(en)
*
|
2007-11-16 |
2009-05-28 |
Christopher Bowman |
Detection of nucleic acid biomarkers using polymerization-based amplification
|
WO2009064485A1
(en)
*
|
2007-11-16 |
2009-05-22 |
Trustees Of Columbia University In The City Of New York |
Antioxidant flavonoid derivatives
|
CN102171234A
(zh)
*
|
2008-08-05 |
2011-08-31 |
康奈尔大学 |
光交联核酸水凝胶
|
KR101829182B1
(ko)
|
2009-04-02 |
2018-03-29 |
플루이다임 코포레이션 |
표적 핵산의 바코딩을 위한 멀티 프라이머 증폭 방법
|
JP2011036150A
(ja)
*
|
2009-08-07 |
2011-02-24 |
Olympus Corp |
標的核酸分子の定量方法及び標的核酸分子定量キット
|
WO2011027966A2
(en)
|
2009-09-03 |
2011-03-10 |
Seegene, Inc. |
Td probe and its uses
|
JP5633133B2
(ja)
*
|
2009-09-30 |
2014-12-03 |
凸版印刷株式会社 |
遺伝子解析装置
|
GB201001088D0
(en)
|
2010-01-23 |
2010-03-10 |
Trillion Genomics Ltd |
Detection
|
WO2011127933A1
(en)
|
2010-04-16 |
2011-10-20 |
Nuevolution A/S |
Bi-functional complexes and methods for making and using such complexes
|
EP2752668A3
(de)
|
2010-07-23 |
2014-10-15 |
Beckman Coulter, Inc. |
System oder Verfahren zur Aufnahme analytischer Einheiten
|
SG194722A1
(en)
|
2011-05-09 |
2013-12-30 |
Fluidigm Corp |
Probe based nucleic acid detection
|
US9446418B2
(en)
|
2011-11-07 |
2016-09-20 |
Beckman Coulter, Inc. |
Robotic arm
|
WO2013070748A1
(en)
|
2011-11-07 |
2013-05-16 |
Beckman Coulter, Inc. |
Magnetic damping for specimen transport system
|
KR20140092375A
(ko)
|
2011-11-07 |
2014-07-23 |
베크만 컬터, 인코포레이티드 |
원심분리기 시스템 및 작업 흐름
|
JP6190380B2
(ja)
|
2011-11-07 |
2017-08-30 |
ベックマン コールター, インコーポレイテッド |
等分機システムおよびワークフロー
|
WO2013070756A2
(en)
|
2011-11-07 |
2013-05-16 |
Beckman Coulter, Inc. |
System and method for processing samples
|
US9046506B2
(en)
|
2011-11-07 |
2015-06-02 |
Beckman Coulter, Inc. |
Specimen container detection
|
US9045803B2
(en)
|
2012-02-29 |
2015-06-02 |
Abbott Molecular Inc. |
Hepatitis B virus typing and resistance assay
|
JP2015530113A
(ja)
|
2012-09-28 |
2015-10-15 |
セファイド |
マイクロrna多重アッセイのための2プライマーpcr
|
CA2922926A1
(en)
|
2013-09-04 |
2015-03-12 |
Fluidigm Corporation |
Proximity assays for detecting nucleic acids and proteins in a single cell
|
US10526601B2
(en)
|
2014-05-23 |
2020-01-07 |
Digenomix Corporation |
Haploidome determination by digitized transposons
|
WO2016028312A1
(en)
|
2014-08-22 |
2016-02-25 |
Cepheid |
Methods of detecting influenza
|
WO2016069853A2
(en)
|
2014-10-30 |
2016-05-06 |
Cepheid |
Methods of detecting ebola
|
PT3234188T
(pt)
|
2014-12-15 |
2020-01-16 |
Cepheid |
Amplificação de ácidos nucleicos em base exponencial superior a 2
|
JP2018509896A
(ja)
|
2015-02-27 |
2018-04-12 |
フリューダイム・コーポレイション |
高処理能力研究用の単一細胞核酸
|
WO2016205233A2
(en)
|
2015-06-15 |
2016-12-22 |
Cepheid |
Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge
|
EP3551766B1
(de)
|
2016-12-12 |
2022-09-14 |
Cepheid |
Integrierte immuno-pcr und nukleinsäureanalyse in einer automatisierten reaktionskartusche
|
CA3046636A1
(en)
|
2016-12-12 |
2018-06-21 |
Cepheid |
Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge
|
US10427162B2
(en)
|
2016-12-21 |
2019-10-01 |
Quandx Inc. |
Systems and methods for molecular diagnostics
|
EP3788377A1
(de)
|
2018-05-04 |
2021-03-10 |
Abbott Laboratories |
Hbv-diagnostische, prognostische und therapeutische verfahren und produkte
|
AU2019371797A1
(en)
|
2018-10-29 |
2021-05-20 |
Cepheid |
Exponential base-3 nucleic acid amplification with reduced amplification time using nested overlapping primers
|
EP3901286A1
(de)
|
2020-04-24 |
2021-10-27 |
Mirnax Biosens, S.L. |
Bivalenter umkehrprimer
|
US20220389497A1
(en)
|
2019-11-04 |
2022-12-08 |
Mirnax Biosens, S.L. |
Bivalent reverse primer
|
EP4172363A1
(de)
|
2020-06-26 |
2023-05-03 |
Cepheid |
Verfahren zum nachweis von sars-cov-2, influenza und rsv
|
BR112023006262A2
(pt)
|
2020-10-06 |
2023-05-09 |
Cepheid |
Métodos de diagnóstico de tuberculose e de diferenciação entre tuberculose ativa e latente
|
EP4419715A1
(de)
|
2021-10-22 |
2024-08-28 |
Cepheid |
Zusammensetzungen und verfahren zur diagnose und behandlung von tuberkulose
|
WO2023212336A1
(en)
|
2022-04-29 |
2023-11-02 |
Cepheid |
Nucleic acid extraction and isolation with heat labile silanes and chemically modified solid supports
|
WO2023225362A1
(en)
|
2022-05-19 |
2023-11-23 |
Cepheid |
Mvp cartridge and methods of use and manufacture
|
WO2024059692A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|
WO2024129998A2
(en)
|
2022-12-16 |
2024-06-20 |
Cepheid |
Mpox clade ii biomarker panel
|
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