ATA70979A - Verfahren zur herstellung von neuen 1-substituierten imidazolderivaten und deren salzen - Google Patents
Verfahren zur herstellung von neuen 1-substituierten imidazolderivaten und deren salzenInfo
- Publication number
- ATA70979A ATA70979A AT0070979A AT70979A ATA70979A AT A70979 A ATA70979 A AT A70979A AT 0070979 A AT0070979 A AT 0070979A AT 70979 A AT70979 A AT 70979A AT A70979 A ATA70979 A AT A70979A
- Authority
- AT
- Austria
- Prior art keywords
- salts
- imidazole derivatives
- substituted imidazole
- producing new
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT184583A AT378772B (de) | 1978-02-01 | 1983-05-19 | Verfahren zur herstellung von neuen 1-substituierten imidazolderivaten und deren salzen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB398478 | 1978-02-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA70979A true ATA70979A (de) | 1983-04-15 |
AT372949B AT372949B (de) | 1983-11-25 |
Family
ID=9768613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0070979A AT372949B (de) | 1978-02-01 | 1979-01-31 | Verfahren zur herstellung von neuen 1-substituierten imidazolderivaten und deren salzen |
Country Status (26)
Country | Link |
---|---|
US (2) | US4416895A (de) |
EP (2) | EP0003732B1 (de) |
JP (1) | JPS54145665A (de) |
AT (1) | AT372949B (de) |
AU (1) | AU533272B2 (de) |
BE (1) | BE873849A (de) |
CA (2) | CA1146549A (de) |
CH (1) | CH643736A5 (de) |
DE (3) | DE2862340D1 (de) |
DK (1) | DK41479A (de) |
ES (1) | ES477305A1 (de) |
FI (1) | FI790314A (de) |
FR (2) | FR2416012A1 (de) |
GB (2) | GB2018136B (de) |
GR (1) | GR65609B (de) |
HU (1) | HU182629B (de) |
IE (1) | IE47649B1 (de) |
IL (1) | IL56556A (de) |
IT (1) | IT1115800B (de) |
LU (1) | LU80863A1 (de) |
MC (1) | MC1241A1 (de) |
NL (1) | NL7900807A (de) |
NZ (1) | NZ189520A (de) |
PT (1) | PT69165A (de) |
SE (1) | SE7900834L (de) |
ZA (1) | ZA79412B (de) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55313A (en) * | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
JPS55115872A (en) * | 1979-02-22 | 1980-09-06 | Wellcome Found | Imidazole derivative and medical composition |
GR73560B (de) * | 1979-02-24 | 1984-03-15 | Pfizer | |
DK157860C (da) * | 1979-06-07 | 1990-07-30 | Shionogi & Co | Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf |
US4218461A (en) * | 1979-08-15 | 1980-08-19 | E. R. Squibb & Sons, Inc. | 2,3-Dihydro-2-[(1H-imidazol-1-yl)-methylene]-1H-inden-1-ones |
PH16249A (en) * | 1980-02-04 | 1983-08-16 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives,its pharmaceutical composition and method of use |
US4321272A (en) * | 1980-08-25 | 1982-03-23 | Syntex (U.S.A.) Inc. | Derivatives of substituted N-alkylimidazoles |
NL8005204A (nl) * | 1980-09-17 | 1982-04-16 | Gist Brocades Nv | Ethenyl-imidazool-derivaten met antimycotische werkzaamheid. |
GR75101B (de) * | 1980-10-23 | 1984-07-13 | Pfizer | |
JPS6036427B2 (ja) * | 1980-12-05 | 1985-08-20 | 塩野義製薬株式会社 | 1−ベンジルイミダゾ−ル誘導体 |
DE3103068A1 (de) * | 1981-01-30 | 1982-08-26 | Basf Ag, 6700 Ludwigshafen | Vinylazole, verfahren zu ihrer herstellung und ihre verwendung bei der bekaempfung von pilzen |
ZA824343B (en) * | 1981-07-01 | 1983-04-27 | Upjohn Co | Pyridinyl- and imidazolyl-benzofurane and benzothiophenes |
ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
GB2115408B (en) * | 1982-02-09 | 1985-10-16 | Ici Plc | Triazole and imidazole derivatives |
EP0091503A1 (de) * | 1982-04-14 | 1983-10-19 | Gist-Brocades N.V. | Verfahren zur Bekämpfung von fungiziden Infektionen |
EP0106060B1 (de) * | 1982-08-14 | 1988-09-28 | The Wellcome Foundation Limited | Imidazol-Derivate und Salze, deren Herstellung und pharmazeutische Zusammenstellungen |
JPS59225183A (ja) * | 1983-02-01 | 1984-12-18 | Yoshitomi Pharmaceut Ind Ltd | ジヒドロベンゾフラン誘導体 |
DE3484023D1 (de) * | 1983-03-03 | 1991-03-07 | Basf Ag | Azolylmethylcycloalkane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
US4536505A (en) * | 1983-05-17 | 1985-08-20 | Ciba-Geigy Corporation | Certain N-(pyridyl) indoles |
PH22076A (en) * | 1983-08-25 | 1988-05-20 | Daiichi Seiyaku Co | Benzocycloalkane derivative |
IT1212791B (it) * | 1983-11-24 | 1989-11-30 | Medea Res Srl | Derivato imidazolico adattivita' vasodilatatrice ed antitrombotica, sua preparazione e composizioni farmaceutiche che lo contengono. |
EP0149426B1 (de) * | 1983-12-20 | 1988-05-04 | Ciba-Geigy Ag | Mikrobizide |
EP0149976A3 (de) * | 1983-12-30 | 1986-12-10 | Ciba-Geigy Ag | Substituierte Imidazole |
US4593029A (en) * | 1984-02-15 | 1986-06-03 | Syntex (U.S.A.) Inc. | Novel ω-(N-imidazolyl)alkyl ethers of 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones |
US4659730A (en) * | 1984-06-18 | 1987-04-21 | Eli Lilly And Company | Aromatase inhibiting imidazole derivatives |
JPS61110266A (ja) * | 1984-11-05 | 1986-05-28 | Omron Tateisi Electronics Co | カード発行方法 |
US4609733A (en) * | 1984-12-27 | 1986-09-02 | Ciba-Geigy Corporation | 3-keto-substituted-N-pyridylindoles |
DE3508905A1 (de) * | 1985-03-13 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Neue imidazolylverbindungen und verfahren zu ihrer herstellung |
IL81264A (en) * | 1986-01-30 | 1990-11-05 | Takeda Chemical Industries Ltd | Quinone derivatives,their production and pharmaceutical compositions containing them |
US5229385A (en) * | 1986-01-30 | 1993-07-20 | Takeda Chemical Industries, Ltd. | Quinone derivatives, their production and use |
US4749713A (en) * | 1986-03-07 | 1988-06-07 | Ciba-Geigy Corporation | Alpha-heterocycle substituted tolunitriles |
IL82401A0 (en) * | 1986-05-06 | 1987-11-30 | Merrell Dow Pharma | Dopamine beta hydroxy-lase inhibiting imidazole derivatives and pharmaceutical compositions containing them |
KR930004646B1 (ko) * | 1986-12-09 | 1993-06-02 | 다나베 세이야꾸 가부시끼가이샤 | 심기능 부전의 예방 및 치료제 |
EP0285356A3 (de) * | 1987-03-30 | 1989-05-31 | Smithkline Beecham Corporation | Dopamin-beta-hydroxylase-Hemmer |
US4837333A (en) * | 1987-05-14 | 1989-06-06 | G. D. Searle & Co. | Substituted alkylidene imidazoles |
DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
IL91542A0 (en) * | 1988-10-06 | 1990-04-29 | Erba Carlo Spa | N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them |
JPH0710862B2 (ja) * | 1989-08-08 | 1995-02-08 | 宇部興産株式会社 | アゾリジン誘導体、その製法及び農園芸用殺菌剤 |
JPH03115267A (ja) * | 1989-09-28 | 1991-05-16 | Maruho Kk | プロピオフエノン誘導体、その製造方法、それを含む中枢性筋弛緩剤および抗痙攣剤 |
US5073566A (en) * | 1989-11-30 | 1991-12-17 | Eli Lilly And Company | Angiotensin ii antagonist 1,3-imidazoles and use thereas |
US5635521A (en) * | 1991-09-23 | 1997-06-03 | Sandoz Ltd. | Imidazolylmethyl-pyridines |
DE4131584A1 (de) * | 1991-09-23 | 1993-03-25 | Sandoz Ag | Imidazolylmethyl-pyridine, ihre herstellung und anwendung als pharmazeutika |
ZA929788B (en) * | 1991-12-18 | 1993-06-22 | Schering Corp | Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring. |
GB9127304D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
US5401851A (en) * | 1992-06-03 | 1995-03-28 | Eli Lilly And Company | Angiotensin II antagonists |
US5612360A (en) * | 1992-06-03 | 1997-03-18 | Eli Lilly And Company | Angiotensin II antagonists |
US5359073A (en) * | 1992-11-24 | 1994-10-25 | G. D. Searle & Co. | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists |
US5262426A (en) * | 1993-01-22 | 1993-11-16 | G. D. Searle & Co. | N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists |
US5360907A (en) * | 1993-06-14 | 1994-11-01 | G.D. Searle & Co. | Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives |
GB9312893D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
WO1995029901A1 (en) * | 1994-04-28 | 1995-11-09 | Uniroyal Chemical Company, Inc. | Fungicidal azole derivatives |
FR2723370B1 (fr) * | 1994-08-02 | 1996-09-13 | Roussel Uclaf | Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
FR2723369B1 (fr) * | 1994-08-02 | 1996-09-13 | Roussel Uclaf | Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
US5652363A (en) * | 1995-10-05 | 1997-07-29 | C.D. Searle & Co. | Pyrido-1,4-oxazinylalkyl-benzamide derivatives |
FR2757511B1 (fr) * | 1996-12-23 | 2001-05-04 | Sanofi Sa | Procede pour la preparation d'un derive de tetrahydropyridine |
US5855869A (en) * | 1996-12-31 | 1999-01-05 | Rhodia Inc. | Microparticulate abrasives |
WO2000069823A1 (en) * | 1999-05-12 | 2000-11-23 | Neurosearch A/S | Ion channel modulating agents |
JP2002262119A (ja) | 2001-02-28 | 2002-09-13 | Sharp Corp | 画像処理装置、画像処理方法、画像処理プログラムを記録した機械読取可能な記録媒体および画像処理プログラム |
JP5165154B2 (ja) * | 2010-04-27 | 2013-03-21 | 日本製紙株式会社 | 細胞分化促進剤およびその用途 |
WO2012052540A1 (en) * | 2010-10-21 | 2012-04-26 | Universitaet Des Saarlandes | Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases |
CN104334565A (zh) | 2012-05-29 | 2015-02-04 | 莫门蒂夫性能材料有限责任公司 | 异氰酸基硅烷的制备 |
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DE488681C (de) * | 1927-02-27 | 1930-01-06 | I G Farbenindustrie Akt Ges | Verfahren zur Darstellung von Imidazolderivaten |
DE1620362A1 (de) * | 1966-05-04 | 1970-04-02 | Shell Int Research | Verfahren zur Herstellung von N-Alkyl- bzw.N-Alkenylimidazolen |
US3592826A (en) * | 1967-05-22 | 1971-07-13 | Union Carbide Corp | Imidazole catalysts for diketene reactions |
GB1321701A (en) * | 1969-10-01 | 1973-06-27 | Continental Pharma | Amino-alcohols their salts and process for prepairing the same |
IE34545B1 (en) * | 1969-10-01 | 1975-06-11 | Continental Pharma | Amino-alcohols,their salts and process for preparing the same |
FR2115153A1 (en) * | 1970-11-30 | 1972-07-07 | Berlin Chemie Veb | 1-acyl-imidazoles - with antiviral activity |
GB1364312A (en) * | 1972-01-25 | 1974-08-21 | Beecham Group Ltd | Biologically active imidazoles |
FR2215153A5 (de) * | 1973-01-19 | 1974-08-19 | Cit Alcatel | |
FR2249616A1 (en) * | 1973-10-31 | 1975-05-30 | Pepro | Fungicidal compositions contg 1-aralkyl benzimidazoles - for treatment of plants and seeds |
JPS5437953B2 (de) * | 1974-04-25 | 1979-11-17 | ||
US3927017A (en) * | 1974-06-27 | 1975-12-16 | Janssen Pharmaceutica Nv | 1-({62 -Aryl-{62 -R-ethyl)imidazoles |
DE2533211A1 (de) * | 1975-07-24 | 1977-02-10 | Heumann Ludwig & Co Gmbh | Verfahren zur herstellung von imidazolderivaten |
US4036975A (en) * | 1975-07-28 | 1977-07-19 | Xyntex (U.S.A) Inc. | 1-[2-(1-Adamantyl)-2-(R-thio)ethyl]imidazoles and 1-[2-(1-adamantyl)-2-(R-oxy)ethyl]imidazoles |
US4118461A (en) * | 1975-12-18 | 1978-10-03 | Rohm And Haas Company | 1-Substituted aralkyl imidazoles |
GB1533706A (en) * | 1976-03-01 | 1978-11-29 | Ici Ltd | Fungicidal imidazoles and 1,2,4-triazoles |
US4150153A (en) * | 1977-05-13 | 1979-04-17 | Syntex (U.S.A.) Inc. | 1-(Naphthylethyl)imidazole derivatives |
US4284641A (en) * | 1977-08-26 | 1981-08-18 | Burroughs Wellcome Co. | Pharmaceutically active imidazole derivatives |
-
1978
- 1978-11-02 EP EP78101294A patent/EP0003732B1/de not_active Expired
- 1978-11-02 DE DE7878101294T patent/DE2862340D1/de not_active Expired
-
1979
- 1979-01-29 MC MC791359A patent/MC1241A1/xx unknown
- 1979-01-31 CA CA000320640A patent/CA1146549A/en not_active Expired
- 1979-01-31 GB GB7903452A patent/GB2018136B/en not_active Expired
- 1979-01-31 ES ES477305A patent/ES477305A1/es not_active Expired
- 1979-01-31 HU HU79WE594A patent/HU182629B/hu unknown
- 1979-01-31 EP EP79100289A patent/EP0003560B1/de not_active Expired
- 1979-01-31 LU LU80863A patent/LU80863A1/xx unknown
- 1979-01-31 IE IE177/79A patent/IE47649B1/en unknown
- 1979-01-31 GR GR58227A patent/GR65609B/el unknown
- 1979-01-31 PT PT7969165A patent/PT69165A/pt unknown
- 1979-01-31 JP JP1028479A patent/JPS54145665A/ja active Pending
- 1979-01-31 DE DE19792903653 patent/DE2903653A1/de not_active Withdrawn
- 1979-01-31 NL NL7900807A patent/NL7900807A/xx not_active Application Discontinuation
- 1979-01-31 NZ NZ189520A patent/NZ189520A/en unknown
- 1979-01-31 DK DK41479A patent/DK41479A/da not_active Application Discontinuation
- 1979-01-31 BE BE193196A patent/BE873849A/xx not_active IP Right Cessation
- 1979-01-31 SE SE7900834A patent/SE7900834L/xx not_active Application Discontinuation
- 1979-01-31 GB GB8137257A patent/GB2098064B/en not_active Expired
- 1979-01-31 CH CH94579A patent/CH643736A5/de not_active IP Right Cessation
- 1979-01-31 AT AT0070979A patent/AT372949B/de not_active IP Right Cessation
- 1979-01-31 DE DE7979100289T patent/DE2966948D1/de not_active Expired
- 1979-01-31 FI FI790314A patent/FI790314A/fi not_active Application Discontinuation
- 1979-01-31 AU AU43808/79A patent/AU533272B2/en not_active Ceased
- 1979-01-31 IL IL56556A patent/IL56556A/xx unknown
- 1979-01-31 IT IT47847/79A patent/IT1115800B/it active
- 1979-01-31 FR FR7902450A patent/FR2416012A1/fr active Granted
- 1979-01-31 ZA ZA79412A patent/ZA79412B/xx unknown
- 1979-09-19 FR FR7923318A patent/FR2429593A1/fr active Granted
-
1981
- 1981-04-02 US US06/250,454 patent/US4416895A/en not_active Expired - Fee Related
- 1981-04-02 US US06/250,481 patent/US4528195A/en not_active Expired - Fee Related
-
1982
- 1982-11-30 CA CA000416728A patent/CA1162855A/en not_active Expired
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