FR2115153A1 - 1-acyl-imidazoles - with antiviral activity - Google Patents

1-acyl-imidazoles - with antiviral activity

Info

Publication number
FR2115153A1
FR2115153A1 FR7135835A FR7135835A FR2115153A1 FR 2115153 A1 FR2115153 A1 FR 2115153A1 FR 7135835 A FR7135835 A FR 7135835A FR 7135835 A FR7135835 A FR 7135835A FR 2115153 A1 FR2115153 A1 FR 2115153A1
Authority
FR
France
Prior art keywords
pref
imidazoles
acyl
antiviral activity
hconh2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7135835A
Other languages
French (fr)
Other versions
FR2115153B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Berlin Chemie AG
Original Assignee
Berlin Chemie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlin Chemie AG filed Critical Berlin Chemie AG
Publication of FR2115153A1 publication Critical patent/FR2115153A1/en
Application granted granted Critical
Publication of FR2115153B1 publication Critical patent/FR2115153B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Cpds. of formula (I) (where R1, R2, R3 and R4 are opt. substd alkyl, cycloalkyl aralkyl or aryl or opt. substd heterocyclic gps. and R2-R4 can also be H; X is CO or SO2) are prepd.(a) by reacting a 2-R2-4-R3-5-R4-imidazole with R1-X-Z (where Z is halogen, pref. Cl or (when X = CO) R1CO.O) in a diluent pref. benzene, diisopropyl ether or acetone (when Z = halogen) or excess R1XZ (when Z = R1CO.O) or (b) by reacting R3CO.CHR4.NHXR1 with HCONH2 at 140-200 degrees C pref. 180-185 degrees C, in a diluent, pref. excess HCONH2.
FR7135835A 1970-11-30 1971-10-05 1-acyl-imidazoles - with antiviral activity Granted FR2115153A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD15162970 1970-11-30

Publications (2)

Publication Number Publication Date
FR2115153A1 true FR2115153A1 (en) 1972-07-07
FR2115153B1 FR2115153B1 (en) 1975-04-18

Family

ID=5483213

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7135835A Granted FR2115153A1 (en) 1970-11-30 1971-10-05 1-acyl-imidazoles - with antiviral activity

Country Status (3)

Country Link
CH (1) CH566996A5 (en)
FR (1) FR2115153A1 (en)
SU (2) SU450804A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721835A1 (en) * 1976-05-13 1977-11-24 Farmatis Srl NEW IMIDAZOLE COMPOUND, METHOD OF MANUFACTURING IT AND PHARMACEUTICAL PRODUCTS CONTAINING IT
EP0003560A2 (en) * 1978-02-01 1979-08-22 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations
EP0044394A2 (en) * 1980-06-11 1982-01-27 BASF Aktiengesellschaft Azolyl-4-nitro-2-trichloromethyl-phenyl sulfones, their preparation and use
EP0332295A2 (en) * 1988-02-10 1989-09-13 Mitsui Petrochemical Industries, Ltd. Novel imidazole derivative

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721835A1 (en) * 1976-05-13 1977-11-24 Farmatis Srl NEW IMIDAZOLE COMPOUND, METHOD OF MANUFACTURING IT AND PHARMACEUTICAL PRODUCTS CONTAINING IT
EP0003560A2 (en) * 1978-02-01 1979-08-22 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations
FR2416012A1 (en) * 1978-02-01 1979-08-31 Wellcome Found DERIVATIVES OF IMIDAZOLE AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
EP0003560A3 (en) * 1978-02-01 1979-10-31 The Wellcome Foundation Limited Imidazole derivatives and salts thereof, their synthesis, and intermediates, and pharmaceutical formulations
EP0044394A2 (en) * 1980-06-11 1982-01-27 BASF Aktiengesellschaft Azolyl-4-nitro-2-trichloromethyl-phenyl sulfones, their preparation and use
EP0044394A3 (en) * 1980-06-11 1982-02-03 BASF Aktiengesellschaft Azolyl-4-nitro-2-trichloromethyl-phenyl sulfones, their preparation and use
EP0332295A2 (en) * 1988-02-10 1989-09-13 Mitsui Petrochemical Industries, Ltd. Novel imidazole derivative
EP0332295A3 (en) * 1988-02-10 1991-10-02 Mitsui Petrochemical Industries, Ltd. Novel imidazole derivative

Also Published As

Publication number Publication date
SU450804A1 (en) 1974-11-25
SU496277A1 (en) 1975-12-25
FR2115153B1 (en) 1975-04-18
CH566996A5 (en) 1975-09-30

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Legal Events

Date Code Title Description
ST Notification of lapse