AT370097B - Verfahren zur herstellung von neuen 3,5-diamino-6-(substituierten phenyl)-1,2,4-triazinen und deren saeureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen 3,5-diamino-6-(substituierten phenyl)-1,2,4-triazinen und deren saeureadditionssalzen

Info

Publication number
AT370097B
AT370097B AT0289680A AT289680A AT370097B AT 370097 B AT370097 B AT 370097B AT 0289680 A AT0289680 A AT 0289680A AT 289680 A AT289680 A AT 289680A AT 370097 B AT370097 B AT 370097B
Authority
AT
Austria
Prior art keywords
triazines
diamino
acid addition
addition salts
substituted phenyl
Prior art date
Application number
AT0289680A
Other languages
German (de)
English (en)
Other versions
ATA289680A (de
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AT370097(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ATA289680A publication Critical patent/ATA289680A/de
Application granted granted Critical
Publication of AT370097B publication Critical patent/AT370097B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0289680A 1979-06-01 1980-05-30 Verfahren zur herstellung von neuen 3,5-diamino-6-(substituierten phenyl)-1,2,4-triazinen und deren saeureadditionssalzen AT370097B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01

Publications (2)

Publication Number Publication Date
ATA289680A ATA289680A (de) 1982-07-15
AT370097B true AT370097B (de) 1983-02-25

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0289680A AT370097B (de) 1979-06-01 1980-05-30 Verfahren zur herstellung von neuen 3,5-diamino-6-(substituierten phenyl)-1,2,4-triazinen und deren saeureadditionssalzen

Country Status (30)

Country Link
US (2) US4486354A (cg-RX-API-DMAC7.html)
EP (2) EP0021121B1 (cg-RX-API-DMAC7.html)
JP (2) JPS5625169A (cg-RX-API-DMAC7.html)
AR (1) AR227521A1 (cg-RX-API-DMAC7.html)
AT (1) AT370097B (cg-RX-API-DMAC7.html)
AU (2) AU530999B2 (cg-RX-API-DMAC7.html)
BG (1) BG60427B2 (cg-RX-API-DMAC7.html)
CA (1) CA1112643A (cg-RX-API-DMAC7.html)
CS (1) CS234018B2 (cg-RX-API-DMAC7.html)
CZ (1) CZ384891A3 (cg-RX-API-DMAC7.html)
DD (1) DD151309A5 (cg-RX-API-DMAC7.html)
DK (1) DK153787C (cg-RX-API-DMAC7.html)
ES (1) ES491998A0 (cg-RX-API-DMAC7.html)
FI (1) FI67844C (cg-RX-API-DMAC7.html)
GE (1) GEP19960470B (cg-RX-API-DMAC7.html)
GR (1) GR68380B (cg-RX-API-DMAC7.html)
HU (1) HU182086B (cg-RX-API-DMAC7.html)
IE (1) IE49823B1 (cg-RX-API-DMAC7.html)
IL (1) IL60201A (cg-RX-API-DMAC7.html)
IT (1) IT1147087B (cg-RX-API-DMAC7.html)
MX (1) MX9202962A (cg-RX-API-DMAC7.html)
MY (1) MY8500062A (cg-RX-API-DMAC7.html)
NL (1) NL950007I2 (cg-RX-API-DMAC7.html)
NZ (1) NZ193890A (cg-RX-API-DMAC7.html)
PL (1) PL124029B1 (cg-RX-API-DMAC7.html)
SU (1) SU1055331A3 (cg-RX-API-DMAC7.html)
UA (1) UA5576A1 (cg-RX-API-DMAC7.html)
YU (1) YU145680A (cg-RX-API-DMAC7.html)
ZA (1) ZA803250B (cg-RX-API-DMAC7.html)
ZW (1) ZW12980A1 (cg-RX-API-DMAC7.html)

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GB9124807D0 (en) * 1991-11-22 1992-01-15 Wellcome Found Pharmaceutical formulations
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IL105986A (en) * 1992-06-12 1998-12-06 Wellcome Found Pharmaceutical preparations containing triazine compounds for the prevention or reduction of tolerable dependence or the opposite of dependency
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
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GB9305692D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
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US10189859B2 (en) * 2013-12-21 2019-01-29 Nektar Therapeutics Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine
US10576086B2 (en) 2015-06-12 2020-03-03 University Of Greenwich Triazine derivatives as interferon-gamma inhibitors
TWI808952B (zh) 2016-12-16 2023-07-21 瑞士商愛杜西亞製藥有限公司 包含t型鈣通道阻斷劑之醫藥組合
TWI826531B (zh) 2018-09-21 2023-12-21 南韓商愛思開生物製藥股份有限公司 具有㗁二唑之化合物及包含該化合物之醫藥組合物
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Family Cites Families (8)

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GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
AT190941B (de) * 1954-09-22 1957-07-25 Chemie Linz Ag Verfahren zur Herstellung neuer Guanylhydrazone
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EP0024351B1 (en) * 1979-08-16 1984-10-31 The Wellcome Foundation Limited Solid pharmaceutical formulation containing substitued phenyl-triazines

Also Published As

Publication number Publication date
IT1147087B (it) 1986-11-19
ZA803250B (en) 1982-01-27
EP0059987A1 (en) 1982-09-15
FI67844C (fi) 1985-06-10
JPS6133163A (ja) 1986-02-17
IE801126L (en) 1980-12-01
IL60201A0 (en) 1980-07-31
ES8104993A1 (es) 1981-05-16
AU5890680A (en) 1980-12-04
IT8048848A0 (it) 1980-05-30
JPH0144179B2 (cg-RX-API-DMAC7.html) 1989-09-26
CZ384891A3 (en) 1993-10-13
EP0059987B1 (en) 1985-08-14
PL224633A1 (cg-RX-API-DMAC7.html) 1981-02-13
BG60427B2 (bg) 1995-03-31
ES491998A0 (es) 1981-05-16
GEP19960470B (en) 1996-08-29
SU1055331A3 (ru) 1983-11-15
CS234018B2 (en) 1985-03-14
JPH0144706B2 (cg-RX-API-DMAC7.html) 1989-09-29
YU145680A (en) 1983-02-28
US4486354A (en) 1984-12-04
ATA289680A (de) 1982-07-15
NL950007I1 (nl) 1995-06-16
NL950007I2 (nl) 1997-02-03
DK233880A (da) 1980-12-02
UA5576A1 (uk) 1994-12-28
AU530999B2 (en) 1983-08-04
DD151309A5 (de) 1981-10-14
EP0021121B1 (en) 1983-05-11
DK153787C (da) 1989-01-16
NZ193890A (en) 1984-07-06
ZW12980A1 (en) 1982-01-06
MX9202962A (es) 1992-07-01
FI801758A7 (fi) 1980-12-02
MY8500062A (en) 1985-12-31
FI67844B (fi) 1985-02-28
DK153787B (da) 1988-09-05
HU182086B (en) 1983-12-28
AR227521A1 (es) 1982-11-15
US4602017A (en) 1986-07-22
IL60201A (en) 1984-05-31
EP0021121A1 (en) 1981-01-07
PL124029B1 (en) 1982-12-31
JPS5625169A (en) 1981-03-10
IE49823B1 (en) 1985-12-25
CA1112643A (en) 1981-11-17
GR68380B (cg-RX-API-DMAC7.html) 1981-12-28
AU566870B2 (en) 1987-11-05

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