AT344332B - Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen - Google Patents

Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Info

Publication number
AT344332B
AT344332B AT153875A AT153875A AT344332B AT 344332 B AT344332 B AT 344332B AT 153875 A AT153875 A AT 153875A AT 153875 A AT153875 A AT 153875A AT 344332 B AT344332 B AT 344332B
Authority
AT
Austria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
acid addition
addition salts
producing new
Prior art date
Application number
AT153875A
Other languages
German (de)
English (en)
Other versions
ATA153875A (de
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ATA153875A publication Critical patent/ATA153875A/de
Application granted granted Critical
Publication of AT344332B publication Critical patent/AT344332B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT153875A 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen AT344332B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
ATA153875A ATA153875A (de) 1977-11-15
AT344332B true AT344332B (de) 1978-07-10

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT153875A AT344332B (de) 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Country Status (25)

Country Link
JP (1) JPS5827275B2 (da)
AT (1) AT344332B (da)
BE (1) BE826440A (da)
BG (3) BG24814A4 (da)
CA (1) CA1049511A (da)
CH (8) CH612425A5 (da)
CS (1) CS188221B2 (da)
DD (1) DD119236A5 (da)
DE (1) DE2411382C3 (da)
DK (1) DK137188C (da)
ES (6) ES440350A1 (da)
FI (1) FI63571C (da)
FR (1) FR2262984B1 (da)
GB (1) GB1496418A (da)
HU (1) HU177408B (da)
IE (1) IE40945B1 (da)
IL (1) IL46760A (da)
NL (1) NL7502724A (da)
NO (1) NO141800C (da)
PH (1) PH14127A (da)
PL (3) PL93499B1 (da)
RO (2) RO69617A (da)
SE (1) SE421919B (da)
SU (3) SU577982A3 (da)
ZA (1) ZA751394B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
AU708076B2 (en) * 1995-03-10 1999-07-29 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックインヒビター
CA2704628C (en) 2007-11-16 2016-11-29 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2687525B1 (en) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
FR2262984A1 (da) 1975-10-03
ZA751394B (en) 1976-11-24
CA1049511A (en) 1979-02-27
PL93700B1 (da) 1977-06-30
ATA153875A (de) 1977-11-15
CH620439A5 (en) 1980-11-28
FI750652A (da) 1975-09-10
IE40945B1 (en) 1979-09-12
HU177408B (en) 1981-10-28
SU588916A3 (ru) 1978-01-15
IE40945L (en) 1975-09-09
CH622014A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
FR2262984B1 (da) 1978-07-28
CH622015A5 (en) 1981-03-13
BE826440A (fr) 1975-09-08
JPS50123675A (da) 1975-09-29
NO750773L (da) 1975-09-10
SU577982A3 (ru) 1977-10-25
ES440348A1 (es) 1977-06-01
SE421919B (sv) 1982-02-08
BG24814A4 (en) 1978-05-12
SU577983A3 (ru) 1977-10-25
CH612425A5 (en) 1979-07-31
CH620681A5 (en) 1980-12-15
DE2411382B2 (de) 1979-01-18
AU7894275A (en) 1976-09-16
ES440349A1 (es) 1977-03-01
CH620440A5 (en) 1980-11-28
DE2411382A1 (de) 1975-09-18
DK137188B (da) 1978-01-30
FI63571C (fi) 1983-07-11
GB1496418A (en) 1977-12-30
RO70051A (ro) 1980-12-30
ES440350A1 (es) 1977-03-16
RO69617A (ro) 1980-08-15
FI63571B (fi) 1983-03-31
NL7502724A (nl) 1975-09-11
DK92975A (da) 1975-09-10
JPS5827275B2 (ja) 1983-06-08
IL46760A (en) 1978-12-17
CS188221B2 (en) 1979-02-28
DD119236A5 (da) 1976-04-12
ES440346A1 (es) 1977-03-01
SE7502592L (da) 1975-09-10
PH14127A (en) 1981-02-26
ES440347A1 (es) 1977-06-01
NO141800B (no) 1980-02-04
NO141800C (no) 1980-06-04
BG24813A4 (en) 1978-05-12
PL93699B1 (da) 1977-06-30
ES440345A1 (es) 1977-03-01
IL46760A0 (en) 1975-05-22
PL93499B1 (da) 1977-05-30
BG25087A3 (en) 1978-07-12
DK137188C (da) 1978-07-03
CH622016A5 (en) 1981-03-13
DE2411382C3 (de) 1979-09-06

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee