AT340895B - Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen

Info

Publication number
AT340895B
AT340895B AT195476A AT195476A AT340895B AT 340895 B AT340895 B AT 340895B AT 195476 A AT195476 A AT 195476A AT 195476 A AT195476 A AT 195476A AT 340895 B AT340895 B AT 340895B
Authority
AT
Austria
Prior art keywords
trifluormethylacylophenone
oximathers
aminoathyl
acid addition
addition salts
Prior art date
Application number
AT195476A
Other languages
German (de)
English (en)
Other versions
ATA195476A (de
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Priority to AT41377A priority Critical patent/AT342568B/de
Priority to AT317277A priority patent/AT342574B/de
Publication of ATA195476A publication Critical patent/ATA195476A/de
Application granted granted Critical
Publication of AT340895B publication Critical patent/AT340895B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT195476A 1975-03-20 1976-03-17 Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen AT340895B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT41377A AT342568B (de) 1975-03-20 1977-01-24 Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
AT317277A AT342574B (de) 1975-03-20 1977-05-04 Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (2)

Publication Number Publication Date
ATA195476A ATA195476A (de) 1977-05-15
AT340895B true AT340895B (de) 1978-01-10

Family

ID=19823424

Family Applications (1)

Application Number Title Priority Date Filing Date
AT195476A AT340895B (de) 1975-03-20 1976-03-17 Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen

Country Status (27)

Country Link
US (1) US4085225A (en:Method)
JP (1) JPS6026776B2 (en:Method)
AR (2) AR211011A1 (en:Method)
AT (1) AT340895B (en:Method)
AU (1) AU505358B2 (en:Method)
BE (1) BE839744A (en:Method)
CA (1) CA1076142A (en:Method)
CH (4) CH626057A5 (en:Method)
DD (1) DD128332A5 (en:Method)
DE (1) DE2610886A1 (en:Method)
DK (1) DK144942C (en:Method)
ES (1) ES446192A1 (en:Method)
FI (1) FI61875C (en:Method)
FR (1) FR2304336A1 (en:Method)
GB (1) GB1535226A (en:Method)
GR (1) GR60052B (en:Method)
HU (1) HU171030B (en:Method)
IE (1) IE43768B1 (en:Method)
IL (1) IL49238A (en:Method)
IT (1) IT1063064B (en:Method)
MX (1) MX9203723A (en:Method)
NL (1) NL7503310A (en:Method)
PL (3) PL101951B1 (en:Method)
SE (1) SE410312B (en:Method)
SU (3) SU635867A3 (en:Method)
YU (1) YU39345B (en:Method)
ZA (1) ZA761434B (en:Method)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
AU6776196A (en) * 1995-08-16 1997-03-12 Eli Lilly And Company Potentiation of serotonin response
IN182588B (en:Method) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (en:Method) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
WO2001078721A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research Aβ42 LOWERING AGENTS
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
WO2001080845A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics (2-aminoethyl) oxime derivatives for the treatment of depression
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
CA2462903C (en) * 2001-10-12 2011-09-20 Serenix Pharmaceuticals, Llc Beta-lactamyl vasopressin v1a antagonists
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
ATE449633T1 (de) 2003-09-12 2009-12-15 Pfizer Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern
ATE473967T1 (de) * 2003-11-26 2010-07-15 Pfizer Prod Inc Aminopyrazolderivate als gsk-3-inhibitoren
ES2515092T3 (es) 2003-12-11 2014-10-29 Sunovion Pharmaceuticals Inc. Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
US20050233010A1 (en) * 2004-04-19 2005-10-20 Satow Philip M Lithium combinations, and uses related thereto
WO2005108683A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2601709C (en) 2005-03-22 2017-02-14 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids
JP2008538573A (ja) 2005-04-22 2008-10-30 ワイス ベンゾフラニルアルカナミン誘導体およびその５−ｈｔ２ｃアゴニストとしての使用
AR056979A1 (es) * 2005-04-22 2007-11-07 Wyeth Corp Derivados de dihidrobenzofuranos y usos de los mismos
US20060252825A1 (en) * 2005-04-22 2006-11-09 Wyeth Crystal forms of {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
US7402687B2 (en) 2005-04-22 2008-07-22 Wyeth Dihydrobenzofuran derivatives and uses thereof
CA2614289A1 (en) * 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
PL1910346T3 (pl) * 2005-07-19 2019-09-30 Azevan Pharmaceuticals, Inc. Beta-laktamowy antagonista wazopresyny fenyloalaniny, cysteiny i seryny
NZ564789A (en) * 2005-07-22 2010-07-30 Myriad Genetics Inc High drug load formulations and dosage forms
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP1942879A1 (en) 2005-10-31 2008-07-16 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007231011A1 (en) * 2006-03-24 2007-10-04 Wyeth New therapeutic combinations for the treatment of depression
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
WO2008034032A2 (en) * 2006-09-14 2008-03-20 Azevan Pharmaceuticals, Inc. Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
EP2125017A2 (en) * 2007-01-11 2009-12-02 Braincells, Inc. Modulation of neurogenesis with use of modafinil
US20110034565A1 (en) 2008-04-18 2011-02-10 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
PT2491038T (pt) 2009-10-23 2016-07-14 Janssen Pharmaceutica Nv Octahidropirrolo[3,4-c]pirrolos disubstituídos como modeladores de recetores de orexina
JP5815552B2 (ja) 2009-12-08 2015-11-17 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ 眼疾患を治療する化合物および方法
ES2858499T3 (es) 2010-07-01 2021-09-30 Azevan Pharmaceuticals Inc Compuestos para su uso en el tratamiento de trastorno explosivo intermitente
BR112013023810A2 (pt) 2011-03-17 2016-12-13 Lupin Ltd composições farmacêuticas de liberação controlada de inibidores seletivos da recaptação de serotonina
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
WO2014178064A2 (en) * 2013-04-03 2014-11-06 Zcl Chemicals Limited "an improved process for the preparation of fluvoxamine maleate"
CN106456578B (zh) 2014-02-07 2020-02-18 匈牙利科学院大学及其他机构附属研究所 Sigma-1受体激动剂化合物的用途
SG10202001065SA (en) 2014-03-28 2020-04-29 Azevan Pharmaceuticals Inc Compositions and methods for treating neurodegenerative diseases
MY197558A (en) 2016-03-10 2023-06-23 Janssen Pharmaceutica Nv Methods of treating depression using orexin-2 receptor antagonists
US12239125B2 (en) 2016-11-24 2025-03-04 SigmaDrugs Kutató Korlátolt Felelsség Társaság Compositions for organ preservation
EP3681871A4 (en) 2017-09-15 2021-05-26 Azevan Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF A BRAIN DAMAGE
KR20220049526A (ko) 2019-07-19 2022-04-21 바이오엑셀 테라퓨틱스 인코포레이티드 비-진정성 덱스메데토미딘 치료 양생법
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
CH629477A5 (de) 1982-04-30
MX9203723A (es) 1992-07-01
DK115976A (da) 1976-09-21
FI61875C (fi) 1982-10-11
PL100052B1 (pl) 1978-08-31
SU620206A3 (ru) 1978-08-15
CH629184A5 (de) 1982-04-15
IE43768L (en) 1976-09-20
SU635867A3 (ru) 1978-11-30
CH629761A5 (de) 1982-05-14
JPS51125345A (en) 1976-11-01
NL7503310A (nl) 1976-09-22
SE410312B (sv) 1979-10-08
AU505358B2 (en) 1979-11-15
ES446192A1 (es) 1977-10-01
IL49238A0 (en) 1976-05-31
HU171030B (hu) 1977-10-28
GB1535226A (en) 1978-12-13
ATA195476A (de) 1977-05-15
SE7603341L (sv) 1976-09-21
DE2610886C2 (en:Method) 1987-09-24
YU71476A (en) 1982-10-31
YU39345B (en) 1984-10-31
DD128332A5 (de) 1977-11-09
PL100614B1 (pl) 1978-10-31
SU645559A3 (ru) 1979-01-30
FI760699A7 (en:Method) 1976-09-21
DE2610886A1 (de) 1976-10-07
PL101951B1 (pl) 1979-02-28
JPS6026776B2 (ja) 1985-06-25
IE43768B1 (en) 1981-05-20
AR211153A1 (es) 1977-10-31
IT1063064B (it) 1985-02-11
GR60052B (en) 1978-04-04
BE839744A (fr) 1976-09-20
FR2304336B1 (en:Method) 1979-09-28
CA1076142A (en) 1980-04-22
AU1214776A (en) 1977-09-22
DK144942B (da) 1982-07-12
ZA761434B (en) 1977-10-26
US4085225A (en) 1978-04-18
IL49238A (en) 1978-08-31
AR211011A1 (es) 1977-10-14
FI61875B (fi) 1982-06-30
DK144942C (da) 1982-12-06
FR2304336A1 (fr) 1976-10-15
CH626057A5 (en:Method) 1981-10-30

Similar Documents

Publication Publication Date Title
AT340895B (de) Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
AT344683B (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saeureadditionssalzen
AT362375B (de) Verfahren zur herstellung von neuen pyridinyl-2 (1h)-pyridinonen und deren saeureadditionssalzen
AT361937B (de) Verfahren zur herstellung von neuen 4-acyl- aminophenyl-aethanolaminen und deren saeure- additionssalzen
AT355563B (de) Verfahren zur herstellung von neuen imidazolyl- oximaethern und von deren saeureadditionssalzen
AT355017B (de) Verfahren zur herstellung von neuen benziso- thiazolonen und deren saeureadditionssalzen
AT347463B (de) Verfahren zur herstellung von neuen 1,1,1- triarylalkylaminen und deren saeureadditions- salzen
AT350552B (de) Verfahren zur herstellung von neuen propargyl- 2-phenylamino-imidazolinen-(2) und deren saeureadditionssalzen
AT353970B (de) Verfahren zur herstellung von neuen 7-methoxy- cephalosporinen und deren salzen
AT344142B (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saeureadditionssalzen
AT346303B (de) Verfahren zur herstellung von neuen 7- aminobenzocycloheptenen und deren saeure- additionssalzen
AT363923B (de) Verfahren zur herstellung von neuen 8-amino-alkyltetracyclononanen und von deren saeureadditionssalzen
AT340896B (de) Verfahren zur herstellung von neuen p-halogen-acylophenon- o - (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA328376A (de) Verfahren zur herstellung von neuen 3-aminomethyl-2-phenylbicyclo(2,2,2)octanen und deren saureadditionssalzen
AT352724B (de) Verfahren zur herstellung von neuen substi- tuierten sulfoximiden und deren salzen
AT342599B (de) Verfahren zur herstellung von neuen indolobenzazepinen und deren saureadditionssalzen
AT340897B (de) Verfahren zur herstellung von neuen p-methylthioacylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT342565B (de) Verfahren zur herstellung von neuen 3,4-dichlorphenon-o-(2-aminoathyl)-oximathern und deren saureadditionssalzen
AT351509B (de) Verfahren zur herstellung von neuen 3-phenoxy-2 -hydroxy-1-phenoxy- oder -1-phenylthioalkyl- amino-propanen und von deren saeureadditions- salzen
AT360033B (de) Verfahren zur herstellung von neuen tetrahydro- -s-triazinthionen und deren saeure- additionssalzen
AT360010B (de) Verfahren zur herstellung von neuen azabicyclo- alkanen und deren physiologisch vertraeglichen saeureadditionssalzen
AT340894B (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl) -oximather und deren saureadditionssalzen
AT342021B (de) Verfahren zur herstellung von neuen p-methylsulfinyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT348979B (de) Verfahren zur herstellung von neuen 7-aminomethylbenzocycloheptenen und deren saeureadditonssalzen
AT349024B (de) Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saeureadditionssalzen

Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELA Expired due to lapse of time
SZA Application filed for a certificate of protection

Free format text: SZ 75/94, 941213

SZW Certificate of protection rejected

Free format text: SZ 75/94, 19941213