AT281798B - Verfahren zur Herstellung von neuen α-(3-Benzoylphenyl)-essigsäuren sowie von deren Salzen - Google Patents
Verfahren zur Herstellung von neuen α-(3-Benzoylphenyl)-essigsäuren sowie von deren SalzenInfo
- Publication number
- AT281798B AT281798B AT432569A AT432569A AT281798B AT 281798 B AT281798 B AT 281798B AT 432569 A AT432569 A AT 432569A AT 432569 A AT432569 A AT 432569A AT 281798 B AT281798 B AT 281798B
- Authority
- AT
- Austria
- Prior art keywords
- benzoylphenyl
- salts
- new
- production
- acetic acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR92828A FR1546478A (fr) | 1967-01-27 | 1967-01-27 | Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation |
FR132526A FR94930E (fr) | 1967-01-27 | 1967-12-15 | Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation. |
Publications (1)
Publication Number | Publication Date |
---|---|
AT281798B true AT281798B (de) | 1970-06-10 |
Family
ID=26174596
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04324/69A AT280248B (de) | 1967-01-27 | 1968-01-26 | Verfahren zur herstellung von neuen alpha-(3-benzoylphenyl)-alkansaeuren sowie ihren optischen isomeren und bzw. oder salzen |
AT432569A AT281798B (de) | 1967-01-27 | 1968-01-26 | Verfahren zur Herstellung von neuen α-(3-Benzoylphenyl)-essigsäuren sowie von deren Salzen |
AT79468A AT280245B (de) | 1967-01-27 | 1968-01-26 | Verfahren zur Herstellung von neuen α-(3-Benzoylphenyl)-alkansäuren sowie von deren Salzen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04324/69A AT280248B (de) | 1967-01-27 | 1968-01-26 | Verfahren zur herstellung von neuen alpha-(3-benzoylphenyl)-alkansaeuren sowie ihren optischen isomeren und bzw. oder salzen |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT79468A AT280245B (de) | 1967-01-27 | 1968-01-26 | Verfahren zur Herstellung von neuen α-(3-Benzoylphenyl)-alkansäuren sowie von deren Salzen |
Country Status (21)
Country | Link |
---|---|
US (1) | US3641127A (de) |
AT (3) | AT280248B (de) |
BE (1) | BE709964A (de) |
CH (1) | CH484863A (de) |
CY (1) | CY668A (de) |
DE (1) | DE1668648C3 (de) |
DK (2) | DK119153B (de) |
ES (3) | ES349842A1 (de) |
FI (1) | FI45953C (de) |
FR (2) | FR1546478A (de) |
GB (1) | GB1164585A (de) |
IE (1) | IE31886B1 (de) |
IL (1) | IL29377A (de) |
LU (1) | LU55356A1 (de) |
MY (1) | MY7300143A (de) |
NL (1) | NL146485B (de) |
NO (2) | NO125672B (de) |
OA (1) | OA03403A (de) |
SE (1) | SE346989B (de) |
SU (1) | SU544364A3 (de) |
YU (3) | YU32373B (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2460984A (en) * | 1944-06-06 | 1949-02-08 | Wright Aeronautical Corp | Pipe connection |
FR2043472A1 (de) * | 1969-05-19 | 1971-02-19 | Rhone Poulenc Sa | |
OA04219A (fr) * | 1971-12-03 | 1979-12-31 | Rhone Poulenc Sa | Nouveau procédé de préparation de l'acide (benzol-3-phényl)-2 propionique et analogues. |
FR2202873A2 (en) * | 1972-10-16 | 1974-05-10 | Rhone Poulenc Sa | 3-benzoylphenyl acetic and 2-(3-benzoyl phenyl) - propionic acids prepn - for use as anti-inflammatories |
FR2163875A5 (en) * | 1971-12-03 | 1973-07-27 | Rhone Poulenc Sa | 3-benzoylphenyl acetic and 2-(3-benzoyl phenyl) - propionic acids prepn - for use as anti-inflammatories |
US3928415A (en) * | 1973-05-08 | 1975-12-23 | Cassella Farbwerke Mainkur Ag | Benzophenone derivatives and process for their production II |
FR2278331A1 (fr) * | 1974-01-24 | 1976-02-13 | Roussel Uclaf | Nouveaux acides carboxyliques et leurs derives, leur application comme medicaments et leur procede de preparation |
US4216326A (en) | 1975-01-20 | 1980-08-05 | Sterling Drug Inc. | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines |
DE2646792C2 (de) * | 1975-10-23 | 1985-05-09 | Mitsubishi Petrochemical Co., Ltd., Tokio/Tokyo | Verfahren zur Herstellung einer α-(arylsubstituierten)-Propionsäure und/oder eines Esters derselben |
YU39415B (en) * | 1978-04-10 | 1984-12-31 | Lek Tovarna Farmacevtskih | Process for preparing 2-(3-benzoyl-phenyl)-propionic acid |
US4417052A (en) | 1980-02-15 | 1983-11-22 | Sterling Drug Inc. | Phenyl-lower-alkyl piperidines and pyrrolidines |
DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
AT370721B (de) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der |
US5166141A (en) * | 1983-11-01 | 1992-11-24 | Scripps Clinic And Research Foundation | Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals |
JP2691760B2 (ja) * | 1987-03-20 | 1997-12-17 | 日本石油化学株式会社 | α―(3―ベンジルフェニル)プロピオン酸誘導体の製造方法 |
US4868214A (en) * | 1987-11-17 | 1989-09-19 | Analgesic Associates | Onset-hastened/enhanced analgesia |
JP2518014B2 (ja) * | 1988-05-31 | 1996-07-24 | 日産化学工業株式会社 | α−置換酢酸の精製方法 |
US5191112A (en) * | 1989-10-17 | 1993-03-02 | Nissan Chemical Industries, Ltd. | Process for optical resolution of (±)-2-(3-benzoyl)-phenylpropionic acid |
US5071988A (en) * | 1989-10-27 | 1991-12-10 | American Home Products Corporation | Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives |
US5218124A (en) * | 1989-10-27 | 1993-06-08 | American Home Products Corporation | Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives as inhibitors of pla2 and lipoxygenase |
DK0525506T4 (da) * | 1991-07-31 | 1999-10-11 | Tessenderlo Chem Nv | Fremgangsmåde til alfa-monoalkylering af arylacetonitriler, arylacetoestere og aryleddikesyrer |
DE4128787A1 (de) * | 1991-08-30 | 1993-03-04 | Bayer Ag | Neue zwischenprodukte und ihre verwendung bei der herstellung von s-ketoprofen |
FR2687915B1 (fr) * | 1992-02-28 | 1995-05-05 | Rhone Poulenc Rorer Sa | Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r). |
US5331000A (en) * | 1992-03-09 | 1994-07-19 | Sepracor Inc. | Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen |
ES2049647B1 (es) * | 1992-07-28 | 1994-12-16 | Menarini Lab | "procedimiento para la preparacion de nuevos derivados del acido 2-(3-benzoilfenil) propionico" |
ES2058024B1 (es) * | 1992-11-10 | 1995-05-01 | Menarini Lab | Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico. |
DE4319438C1 (de) * | 1993-06-11 | 1994-06-01 | Gerd Dr Dr Geislinger | Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren |
CA2185805A1 (en) * | 1994-03-18 | 1995-09-28 | Georg Frank | Low dosage ketoprofen |
JPH08151344A (ja) * | 1994-09-26 | 1996-06-11 | Nagase & Co Ltd | 2−(3−ベンゾイルフェニル)プロピオン酸の光学分割方法 |
ES2109859B1 (es) * | 1994-11-23 | 1998-08-16 | Menarini Lab | Nuevos derivados arilpropionicos con accion analgesica y procedimiento para su obtencion. |
US6080888A (en) * | 1997-01-08 | 2000-06-27 | Albemarle Corporation | Preparation of olefinic compounds and carboxylic derivatives thereof |
US6096920A (en) * | 1997-01-08 | 2000-08-01 | Albemarle Corporation | Preparation of carboxylic compounds and their derivatives |
US5792886A (en) * | 1997-01-08 | 1998-08-11 | Albemarle Corporation | Production of racemic 2-(6-methoxy-2-naphthyl) propionic acid of precursors thereof |
US6268526B1 (en) | 1998-12-16 | 2001-07-31 | Albemarle Corporation | Palladium catalyzed carbonylation process utilizing aromatic substituted alcohols and/or aromatic substituted alkyl halides |
IT1308633B1 (it) | 1999-03-02 | 2002-01-09 | Nicox Sa | Nitrossiderivati. |
US20080021085A1 (en) * | 2000-04-13 | 2008-01-24 | Mayo Foundation For Medical Education And Research | Method of reducing abeta42 and treating diseases |
AU2001257022B2 (en) * | 2000-04-13 | 2005-02-03 | Mayo Foundation For Medical Education And Research | Abeta 42 lowering agents |
IT1318674B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Faramaci per l'incontinenza. |
IT1318673B1 (it) * | 2000-08-08 | 2003-08-27 | Nicox Sa | Farmaci per le disfunzioni sessuali. |
US20030027867A1 (en) * | 2001-06-29 | 2003-02-06 | Myriad Genetics, Incorporated | Use of R-NSAID compounds for anti-HIV treatment |
NZ538727A (en) * | 2002-09-20 | 2008-01-31 | Nicox Sa | Manufacturing process for NO-donating compounds such as NO-donating diclofenac |
US7090859B2 (en) * | 2002-12-13 | 2006-08-15 | Ronald Thomas Haas | Ketoprofen compositions and methods of making them |
EP1603548A4 (de) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen |
JP2007528857A (ja) * | 2003-07-11 | 2007-10-18 | ミリアド ジェネティクス, インコーポレイテッド | アルツハイマー病の処置のための薬学的方法、投与レジメンおよび投薬形態 |
US20050171207A1 (en) * | 2003-09-26 | 2005-08-04 | Myriad Genetics, Incorporated | Method and composition for combination treatment of neurodegenerative disorders |
US20060047171A1 (en) * | 2003-12-22 | 2006-03-02 | Harold Meckler | Catalytic hydrogenation of nitriles to produce capsaicinoid derivatives and amine compounds, and methods for purifying and obtaining the polymorphs thereof |
US20070293538A1 (en) * | 2004-04-13 | 2007-12-20 | Myriad Genetics, Incorporated | Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders |
EP1745180A1 (de) * | 2004-04-29 | 2007-01-24 | Keystone Retaining Wall Systems, Inc. | Frontverkleidung für stützwände |
CA2618985A1 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
US20070015832A1 (en) * | 2005-07-14 | 2007-01-18 | Myriad Genetics, Incorporated | Methods of treating overactive bladder and urinary incontinence |
EA200800360A1 (ru) * | 2005-07-22 | 2008-06-30 | Мириад Дженетикс, Инк. | Формуляции с высоким содержанием лекарства и дозированные формы |
EP2046119A2 (de) * | 2006-07-07 | 2009-04-15 | Myriad Genetics, Inc. | Behandlung von psychiatrischen störungen |
LT5696B (lt) | 2009-01-22 | 2010-11-25 | Sanofi-Synthelabo (India) Ltd, Gidc | Aktyvių ingredientų, turinčių nesteroidinį priešuždegiminį vaistą ir kolchikozido darinį, naujas derinys |
ES2432222B1 (es) | 2012-04-30 | 2014-06-10 | Farmalider S.A. | Composición farmacéutica inyectable de dexketoprofeno y tramadol |
WO2014007779A1 (en) | 2012-07-06 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Orally-disintegrating formulations of dexketoprofen |
WO2014007780A1 (en) | 2012-07-06 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Orally-disintegrating formulations of dexketoprofen |
EP2730271B1 (de) | 2012-11-11 | 2018-01-24 | Symrise AG | Wässrige Zubereitungen |
EP2772245B1 (de) | 2013-02-27 | 2018-08-22 | Symrise AG | Ingwerextrakt zum Schutz von Stammzellen |
EP2862852B1 (de) | 2013-10-18 | 2018-07-04 | Symrise AG | Harnstoffderivate für den Schutz von Stammzellen |
MX2016007869A (es) | 2013-12-16 | 2016-10-07 | Zoetis Services Llc | Composiciones de ketoprofeno de accion prolongada. |
EP2921157B1 (de) | 2014-03-18 | 2017-08-16 | Symrise AG | Beschichtetes Titandioxid zur Verminderung des Bleicheffektes auf der Haut |
EP2939710B1 (de) | 2014-04-29 | 2020-06-17 | Symrise AG | Aktive Mischungen |
EP3045161A1 (de) | 2015-01-18 | 2016-07-20 | Symrise AG | Aktive Zusammensetzung enthaltend 1,2-Hexandiol und 1,2-Octandiol |
-
1967
- 1967-01-27 FR FR92828A patent/FR1546478A/fr not_active Expired
- 1967-12-15 FR FR132526A patent/FR94930E/fr not_active Expired
-
1968
- 1968-01-18 OA OA53169A patent/OA03403A/xx unknown
- 1968-01-19 NL NL686800880A patent/NL146485B/xx not_active IP Right Cessation
- 1968-01-24 NO NO0304/68A patent/NO125672B/no unknown
- 1968-01-25 IE IE107/68A patent/IE31886B1/xx unknown
- 1968-01-25 FI FI680194A patent/FI45953C/fi active
- 1968-01-25 US US700375A patent/US3641127A/en not_active Expired - Lifetime
- 1968-01-26 YU YU0188/68A patent/YU32373B/xx unknown
- 1968-01-26 CH CH121968A patent/CH484863A/fr not_active IP Right Cessation
- 1968-01-26 IL IL29377A patent/IL29377A/xx unknown
- 1968-01-26 BE BE709964D patent/BE709964A/xx not_active IP Right Cessation
- 1968-01-26 DE DE1668648A patent/DE1668648C3/de not_active Expired
- 1968-01-26 AT AT04324/69A patent/AT280248B/de active
- 1968-01-26 AT AT432569A patent/AT281798B/de not_active IP Right Cessation
- 1968-01-26 LU LU55356D patent/LU55356A1/xx unknown
- 1968-01-26 DK DK31668AA patent/DK119153B/da not_active IP Right Cessation
- 1968-01-26 SE SE01090/68A patent/SE346989B/xx unknown
- 1968-01-26 GB GB4326/68A patent/GB1164585A/en not_active Expired
- 1968-01-26 AT AT79468A patent/AT280245B/de not_active IP Right Cessation
- 1968-01-27 ES ES349842A patent/ES349842A1/es not_active Expired
- 1968-05-03 ES ES353484A patent/ES353484A1/es not_active Expired
- 1968-05-03 ES ES353485A patent/ES353485A1/es not_active Expired
-
1969
- 1969-01-06 SU SU1295338A patent/SU544364A3/ru active
-
1970
- 1970-03-24 DK DK151970AA patent/DK125550B/da not_active IP Right Cessation
-
1971
- 1971-10-07 NO NO03695/71*[A patent/NO126177B/no unknown
-
1973
- 1973-01-05 CY CY66873A patent/CY668A/xx unknown
- 1973-03-27 YU YU820/73A patent/YU34657B/xx unknown
- 1973-07-27 YU YU819/73A patent/YU34656B/xx unknown
- 1973-12-30 MY MY1343/73A patent/MY7300143A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO125672B (de) | 1972-10-16 |
NO126177B (de) | 1973-01-02 |
FR94930E (fr) | 1970-01-23 |
YU32373B (en) | 1974-10-31 |
NL146485B (nl) | 1975-07-15 |
DE1668648B2 (de) | 1973-07-19 |
YU18868A (en) | 1974-04-30 |
DE1668648A1 (de) | 1971-09-02 |
AT280248B (de) | 1970-04-10 |
YU34657B (en) | 1979-12-31 |
YU82073A (en) | 1979-07-10 |
FR1546478A (fr) | 1968-11-22 |
SU544364A3 (ru) | 1977-01-25 |
CH484863A (fr) | 1970-01-31 |
US3641127A (en) | 1972-02-08 |
MY7300143A (en) | 1973-12-31 |
DK119153B (da) | 1970-11-23 |
FI45953C (fi) | 1972-11-10 |
ES353484A1 (es) | 1970-01-16 |
OA03403A (fr) | 1970-12-15 |
YU81973A (en) | 1979-07-10 |
IE31886B1 (en) | 1973-02-07 |
AT280245B (de) | 1970-04-10 |
IL29377A (en) | 1971-04-28 |
BE709964A (de) | 1968-07-26 |
IE31886L (en) | 1968-07-27 |
SE346989B (de) | 1972-07-24 |
CY668A (en) | 1973-01-05 |
GB1164585A (en) | 1969-09-17 |
ES353485A1 (es) | 1969-10-16 |
DK125550B (da) | 1973-03-05 |
YU34656B (en) | 1979-12-31 |
NL6800880A (de) | 1968-07-29 |
DE1668648C3 (de) | 1974-02-21 |
LU55356A1 (de) | 1968-08-30 |
FI45953B (de) | 1972-07-31 |
ES349842A1 (es) | 1969-04-16 |
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