AR194688A1 - Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazina - Google Patents

Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazina

Info

Publication number
AR194688A1
AR194688A1 AR248326A AR24832673A AR194688A1 AR 194688 A1 AR194688 A1 AR 194688A1 AR 248326 A AR248326 A AR 248326A AR 24832673 A AR24832673 A AR 24832673A AR 194688 A1 AR194688 A1 AR 194688A1
Authority
AR
Argentina
Prior art keywords
hydroxibencil
benzhidril
piperazine
procedure
obtaining
Prior art date
Application number
AR248326A
Other languages
English (en)
Spanish (es)
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2226767A external-priority patent/DE2226767A1/de
Priority claimed from DE19732312212 external-priority patent/DE2312212A1/de
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Application granted granted Critical
Publication of AR194688A1 publication Critical patent/AR194688A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
AR248326A 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazina AR194688A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2226767A DE2226767A1 (de) 1972-06-02 1972-06-02 N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung
DE19732312212 DE2312212A1 (de) 1973-03-12 1973-03-12 N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung

Publications (1)

Publication Number Publication Date
AR194688A1 true AR194688A1 (es) 1973-07-31

Family

ID=25763357

Family Applications (5)

Application Number Title Priority Date Filing Date
AR248325A AR196936A1 (es) 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p- hidroxibencil-piperazina
AR248327A AR201001A1 (es) 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas
AR248326A AR194688A1 (es) 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazina
AR252417A AR204987A1 (es) 1972-06-02 1974-01-01 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas
AR252416A AR200764A1 (es) 1972-06-02 1974-02-18 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AR248325A AR196936A1 (es) 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p- hidroxibencil-piperazina
AR248327A AR201001A1 (es) 1972-06-02 1973-05-31 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas

Family Applications After (2)

Application Number Title Priority Date Filing Date
AR252417A AR204987A1 (es) 1972-06-02 1974-01-01 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas
AR252416A AR200764A1 (es) 1972-06-02 1974-02-18 Procedimiento para la obtencion de n-benzhidril-n'-p-hidroxibencil-piperazinas

Country Status (26)

Country Link
US (1) US3868377A (ja)
JP (1) JPS4948687A (ja)
AR (5) AR196936A1 (ja)
AT (3) AT331802B (ja)
AU (1) AU470393B2 (ja)
BG (3) BG20595A3 (ja)
CA (1) CA980347A (ja)
CH (4) CH579064A5 (ja)
CS (4) CS182248B2 (ja)
DD (1) DD106644A5 (ja)
DK (1) DK139751C (ja)
EG (1) EG11434A (ja)
ES (3) ES415464A1 (ja)
FI (1) FI55656C (ja)
FR (1) FR2186265B1 (ja)
GB (1) GB1386916A (ja)
HU (1) HU165312B (ja)
IE (1) IE37717B1 (ja)
IL (1) IL42384A (ja)
NL (1) NL7306771A (ja)
NO (1) NO138026C (ja)
PH (1) PH9485A (ja)
PL (3) PL91050B1 (ja)
RO (3) RO68378A (ja)
SE (1) SE396385B (ja)
SU (4) SU507238A3 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59101475A (ja) * 1982-12-02 1984-06-12 Nippon Chemiphar Co Ltd 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
HU186656B (en) * 1982-12-28 1985-09-30 Richter Gedeon Vegyeszet Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them
GB8320701D0 (en) * 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agent
JPS60222472A (ja) * 1984-03-30 1985-11-07 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
ATE107296T1 (de) * 1988-08-05 1994-07-15 Nippon Chemiphar Co Optisch aktive piperazin-derivate.
FR2661176B1 (fr) * 1990-04-20 1992-06-12 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
CA2153979C (en) * 1993-12-08 2003-10-21 Mark Hellberg Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
KR20110022635A (ko) * 2008-06-02 2011-03-07 시플라 리미티드 레보세티리진의 합성방법 및 이에 사용하기 위한 중간체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2709169A (en) * 1955-05-24 X c chs
US3051710A (en) * 1959-12-21 1962-08-28 Lakeside Lab Inc Glycolic acid amide derivatives of piperazine and use thereof

Also Published As

Publication number Publication date
NL7306771A (ja) 1973-12-04
NO138026C (no) 1978-06-14
SE396385B (sv) 1977-09-19
FR2186265B1 (ja) 1976-03-05
AT331252B (de) 1976-08-10
SU508196A3 (ru) 1976-03-25
NO138026B (no) 1978-03-06
CS178429B2 (ja) 1977-09-15
JPS4948687A (ja) 1974-05-11
CH574949A5 (ja) 1976-04-30
BG20595A3 (ja) 1975-12-05
IL42384A (en) 1976-12-31
SU530644A3 (ru) 1976-09-30
RO68379A (ro) 1981-11-24
DD106644A5 (ja) 1974-06-20
FI55656C (fi) 1979-09-10
PH9485A (en) 1976-01-08
CS182234B2 (en) 1978-04-28
ES415464A1 (es) 1976-05-01
CS178430B2 (ja) 1977-09-15
BG20596A3 (ja) 1975-12-05
ATA483173A (de) 1975-12-15
AR201001A1 (es) 1975-02-06
AU470393B2 (en) 1976-03-11
US3868377A (en) 1975-02-25
PL91050B1 (ja) 1977-02-28
SU577995A3 (ru) 1977-10-25
ES415465A1 (es) 1976-05-16
AU5634373A (en) 1974-12-05
AT331802B (de) 1976-08-25
RO62900A (ro) 1982-10-26
FI55656B (fi) 1979-05-31
ATA483273A (de) 1975-11-15
AR204987A1 (es) 1976-03-31
DK139751B (da) 1979-04-09
CH594651A5 (ja) 1978-01-13
IE37717B1 (en) 1977-09-28
CH579064A5 (ja) 1976-08-31
IL42384A0 (en) 1973-07-30
CA980347A (en) 1975-12-23
EG11434A (en) 1977-09-30
SU507238A3 (ru) 1976-03-15
PL97129B1 (pl) 1978-02-28
IE37717L (en) 1973-12-02
ES415466A1 (es) 1976-05-16
DK139751C (da) 1979-09-17
RO68378A (ro) 1982-02-01
GB1386916A (en) 1975-03-12
AR200764A1 (es) 1974-12-13
FR2186265A1 (ja) 1974-01-11
CH593959A5 (ja) 1977-12-30
ATA483073A (de) 1975-12-15
CS182248B2 (en) 1978-04-28
HU165312B (ja) 1974-08-28
BG20371A3 (ja) 1975-11-05
AT331801B (de) 1976-08-25
PL94759B1 (pl) 1977-08-31
AR196936A1 (es) 1974-02-28

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