AR119878A2 - Composiciones y métodos para detectar un contaminante biológico - Google Patents
Composiciones y métodos para detectar un contaminante biológicoInfo
- Publication number
- AR119878A2 AR119878A2 ARP200102452A ARP200102452A AR119878A2 AR 119878 A2 AR119878 A2 AR 119878A2 AR P200102452 A ARP200102452 A AR P200102452A AR P200102452 A ARP200102452 A AR P200102452A AR 119878 A2 AR119878 A2 AR 119878A2
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- methods
- detect
- biological contaminant
- false
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000356 contaminant Substances 0.000 title 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000012569 microbial contaminant Substances 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 238000003753 real-time PCR Methods 0.000 abstract 1
- 238000011897 real-time detection Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se proveen composiciones y métodos útiles para la determinación de si un contaminante microbiano está presente en un proceso de producción de agentes terapéuticos biológicos. Específicamente, se proveen un plásmido control de amplificación positivo artificial y una sonda de detección de PCR cuantitativa única, lo cual posibilita la detección rápida y en tiempo real de un resultado falso positivo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562139321P | 2015-03-27 | 2015-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR119878A2 true AR119878A2 (es) | 2022-01-19 |
Family
ID=56297073
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160100814A AR104110A1 (es) | 2015-03-27 | 2016-03-28 | Composiciones y métodos para detectar un contaminante biológico |
ARP200102452A AR119878A2 (es) | 2015-03-27 | 2020-09-01 | Composiciones y métodos para detectar un contaminante biológico |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP160100814A AR104110A1 (es) | 2015-03-27 | 2016-03-28 | Composiciones y métodos para detectar un contaminante biológico |
Country Status (20)
Country | Link |
---|---|
US (3) | US10669594B2 (es) |
EP (3) | EP3699298B1 (es) |
JP (4) | JP6670847B2 (es) |
KR (2) | KR102662675B1 (es) |
CN (2) | CN107960108B (es) |
AR (2) | AR104110A1 (es) |
AU (2) | AU2016243498B2 (es) |
BR (1) | BR112017020582A2 (es) |
CA (2) | CA3226784A1 (es) |
DK (1) | DK3274469T3 (es) |
EA (2) | EA202190319A1 (es) |
ES (1) | ES2804845T3 (es) |
IL (4) | IL302434A (es) |
MX (2) | MX2017012437A (es) |
PL (1) | PL3274469T3 (es) |
PT (1) | PT3274469T (es) |
SG (2) | SG11201707690QA (es) |
TW (3) | TW202336236A (es) |
WO (1) | WO2016160572A1 (es) |
ZA (2) | ZA201706797B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202336236A (zh) | 2015-03-27 | 2023-09-16 | 美商再生元醫藥公司 | 偵測生物污染物之組成物及方法 |
CN110997725A (zh) | 2017-06-12 | 2020-04-10 | 蓝鳍生物医药公司 | 抗-il1rap抗体和抗体药物缀合物 |
US20190093149A1 (en) * | 2017-09-27 | 2019-03-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Assays for detecting multiple tick-borne pathogens |
CN112105747A (zh) * | 2018-01-30 | 2020-12-18 | 拜奥法尔防护有限责任公司 | 用于验证核酸扩增测定的方法和系统 |
KR20200135822A (ko) * | 2018-03-20 | 2020-12-03 | 루마사이트 엘엘씨 | 레이저력 사이톨로지를 사용한 고급 생물리적 및 생화학적 세포 모니터링 및 정량화 |
US11702653B2 (en) | 2018-05-21 | 2023-07-18 | Battelle Memorial Institute | Control compositions and methods for sequencing |
US11441176B2 (en) | 2018-12-13 | 2022-09-13 | Battelle Memorial Institute | Methods and control compositions for a quantitative polymerase chain reaction |
KR102278112B1 (ko) * | 2020-07-10 | 2021-07-15 | (주)하임바이오텍 | 특정 인공 뉴클레오타이드 서열을 이용한 위양성 판단용 조성물 및 이를 이용한 위양성 판단 방법 |
KR102532614B1 (ko) * | 2020-09-18 | 2023-05-16 | 한국식품연구원 | 가공식품 및 농산물의 설치류 오염여부를 판별하는 방법 |
AU2021401989A1 (en) * | 2020-12-17 | 2023-06-29 | Amgen Inc. | Real time pcr method to detect bovine parvovirus 3 |
KR20230011040A (ko) * | 2021-07-13 | 2023-01-20 | 재단법인 바이오나노헬스가드연구단 | 미생물 현장 오염 검출용 조성물 및 이의 용도 |
CN114561492A (zh) * | 2022-02-28 | 2022-05-31 | 宁夏回族自治区疾病预防控制中心(宁夏回族自治区性病艾滋病防治中心) | 一种新冠病毒核酸检测阳性质控品及其制备方法和用途 |
CN116814848B (zh) * | 2023-04-12 | 2024-03-19 | 中国医学科学院医学实验动物研究所 | 基于荧光raa检测小鼠微小病毒的引物和探针及方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US5585254A (en) * | 1987-08-21 | 1996-12-17 | University Of Colorado Foundation, Inc. | Autonomous parvovirus gene delivery vehicles and expression vectors |
US5371241A (en) | 1991-07-19 | 1994-12-06 | Pharmacia P-L Biochemicals Inc. | Fluorescein labelled phosphoramidites |
US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
ATE462791T1 (de) * | 1999-08-13 | 2010-04-15 | Deutsches Krebsforsch | Parvovirus ns1 varianten |
AT409383B (de) | 1999-12-22 | 2002-07-25 | Baxter Ag | Verfahren zur detektion und quantifizierung von nukleinsäuren in einer probe |
US20020177222A1 (en) * | 2000-08-10 | 2002-11-28 | Sikun Li | Replication competent AAV helper functions |
CZ308201B6 (cs) * | 2001-06-28 | 2020-02-26 | Grifols Worldwide Operations Limited | Diagnostické zkoušky pro parvovirus B19 |
JP3727317B2 (ja) | 2002-03-08 | 2005-12-14 | エイエスエムエル ネザランドズ ベスローテン フエンノートシャップ | リソグラフィに使用するためのマスク、マスクを作成する方法、リソグラフィ装置、およびデバイス製造方法 |
WO2004044247A2 (en) * | 2002-11-12 | 2004-05-27 | Genolife | One step real-time rt pcr kits for the universal detection of organisms in industrial products |
WO2004104229A2 (en) * | 2003-05-16 | 2004-12-02 | Vickery Michael C L | Internal control nucleic acid molecule for nucleic acid amplification systems |
DE102006034844B3 (de) | 2006-07-27 | 2007-12-06 | DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH | Zusammensetzungen und Verfahren zur Amplifikation von Hepatitis A-Viren (HAV) und/oder Parvoviren B19 (PB19) mittels Multiplex-PCR |
PL2150617T3 (pl) | 2007-06-04 | 2015-04-30 | Regeneron Pharma | Wzmocniona ekspresja i regiony stabilności |
EP2098599A1 (en) | 2008-03-05 | 2009-09-09 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Composition comprising an oligonucleotide mixture for the detection of contaminations in cell cultures |
WO2010111509A1 (en) * | 2009-03-25 | 2010-09-30 | Life Technologies Corporation | Discriminatory positive/extraction control dna |
CN102471378B (zh) | 2009-06-26 | 2014-04-02 | 瑞泽恩制药公司 | 容易地分离的具有天然免疫球蛋白形式的双特异性抗体 |
ES2531581T3 (es) * | 2010-10-21 | 2015-03-17 | Deutsches Krebsforschungszentrum | Reorientación de parvovirus de rata H-1PV hacia células oncológicas mediante manipulación genética de su cápside |
AU2012221740B2 (en) * | 2011-02-25 | 2016-11-17 | Novartis Ag | Exogenous internal positive control |
CN102206713B (zh) * | 2011-04-06 | 2013-01-02 | 浙江大学 | 三重荧光定量rt-pcr检测试剂盒及用途 |
GB201203568D0 (en) * | 2012-02-29 | 2012-04-11 | Vela Operations Pte Ltd | Real time PCR detection of streptococcus |
HU230463B1 (hu) * | 2012-07-02 | 2016-07-28 | Ud-Genomed Medical Genomic Technologies Kft. | Kontroll rendszer immunprecipitációs vizsgálatokhoz |
WO2014055515A1 (en) * | 2012-10-02 | 2014-04-10 | Neurophage Pharmaceuticals, Inc. | Use of p3 of bacteriophage fusion proteins as amyloid binding agents |
GB2525024A (en) * | 2014-04-10 | 2015-10-14 | Vela Operations Pte Ltd | Universal controls for sequencing assays |
TW202336236A (zh) | 2015-03-27 | 2023-09-16 | 美商再生元醫藥公司 | 偵測生物污染物之組成物及方法 |
-
2016
- 2016-03-24 TW TW112118669A patent/TW202336236A/zh unknown
- 2016-03-24 TW TW105109119A patent/TWI735433B/zh active
- 2016-03-24 TW TW110125474A patent/TWI804917B/zh active
- 2016-03-25 PL PL16734060T patent/PL3274469T3/pl unknown
- 2016-03-25 US US15/080,859 patent/US10669594B2/en active Active
- 2016-03-25 CA CA3226784A patent/CA3226784A1/en active Pending
- 2016-03-25 SG SG11201707690QA patent/SG11201707690QA/en unknown
- 2016-03-25 BR BR112017020582-3A patent/BR112017020582A2/pt active Search and Examination
- 2016-03-25 IL IL302434A patent/IL302434A/en unknown
- 2016-03-25 KR KR1020177031064A patent/KR102662675B1/ko active IP Right Grant
- 2016-03-25 MX MX2017012437A patent/MX2017012437A/es unknown
- 2016-03-25 EP EP20164343.4A patent/EP3699298B1/en active Active
- 2016-03-25 PT PT167340603T patent/PT3274469T/pt unknown
- 2016-03-25 WO PCT/US2016/024216 patent/WO2016160572A1/en active Application Filing
- 2016-03-25 DK DK16734060.3T patent/DK3274469T3/da active
- 2016-03-25 EA EA202190319A patent/EA202190319A1/ru unknown
- 2016-03-25 CN CN201680025470.0A patent/CN107960108B/zh active Active
- 2016-03-25 SG SG10202006108RA patent/SG10202006108RA/en unknown
- 2016-03-25 CA CA2980915A patent/CA2980915C/en active Active
- 2016-03-25 KR KR1020247014130A patent/KR20240063188A/ko active Search and Examination
- 2016-03-25 EP EP24161139.1A patent/EP4361290A2/en active Pending
- 2016-03-25 EA EA201792155A patent/EA037740B1/ru unknown
- 2016-03-25 JP JP2017550633A patent/JP6670847B2/ja active Active
- 2016-03-25 AU AU2016243498A patent/AU2016243498B2/en active Active
- 2016-03-25 EP EP16734060.3A patent/EP3274469B1/en active Active
- 2016-03-25 ES ES16734060T patent/ES2804845T3/es active Active
- 2016-03-25 CN CN202210143904.4A patent/CN114875175A/zh active Pending
- 2016-03-28 AR ARP160100814A patent/AR104110A1/es unknown
-
2017
- 2017-09-27 IL IL254731A patent/IL254731B/en active IP Right Grant
- 2017-09-27 MX MX2021007667A patent/MX2021007667A/es unknown
- 2017-10-09 ZA ZA2017/06797A patent/ZA201706797B/en unknown
-
2018
- 2018-09-12 ZA ZA2018/06101A patent/ZA201806101B/en unknown
-
2020
- 2020-03-02 JP JP2020034913A patent/JP6894026B2/ja active Active
- 2020-04-22 US US16/855,217 patent/US11549154B2/en active Active
- 2020-09-01 AR ARP200102452A patent/AR119878A2/es unknown
-
2021
- 2021-03-17 IL IL281579A patent/IL281579B/en unknown
- 2021-06-02 JP JP2021092874A patent/JP7385623B2/ja active Active
- 2021-12-28 IL IL289447A patent/IL289447A/en unknown
-
2022
- 2022-10-05 AU AU2022246398A patent/AU2022246398A1/en active Pending
-
2023
- 2023-05-04 US US18/061,712 patent/US20230295747A1/en active Pending
- 2023-11-10 JP JP2023191978A patent/JP2023184743A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR119878A2 (es) | Composiciones y métodos para detectar un contaminante biológico | |
WO2015195949A3 (en) | Methods, compositions, and devices for rapid analysis of biological markers | |
WO2014194113A3 (en) | Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients | |
EP3862439A3 (en) | Liver cancer detection kit or device, and detection method | |
MX2017005159A (es) | Composiciones y metodos para detectar un virus de rna. | |
BR112016029583A2 (pt) | ?kit ou dispositivo para a detecção de câncer esofágico e método de detecção? | |
WO2015128272A3 (en) | Photo-selective method for biological sample analysis field | |
MX2022014633A (es) | Metodos para detectar norovirus. | |
PH12017501967A1 (en) | Maize plant dbn9936 and method for use in detecting nucleic acid sequence thereof | |
EP2576833A4 (en) | METHOD AND DEVICE FOR THE POINT-OF-CARE DETECTION OF NUCLEIC ACID IN A SAMPLE | |
EP3287791A4 (en) | BLOOD SAMPLE COAGULATION CAPACITY ASSESSMENT METHOD, AND REAGENT, REAGENT KIT AND DEVICE FOR USE THEREIN | |
CL2015001568A1 (es) | Métodos de detección multiplex de ácidos nucleicos | |
PH12017500798A1 (en) | Pna probes, kits and methods for detecting human papillomavirus genotypes of human papillomavirus | |
EP3081653A4 (en) | Method for detecting nucleic acid using asymmetric isothermal amplification of nucleic acid and signal probe | |
MA45489A (fr) | Procédés de culture de cellules, kits et appareil associés | |
MX2015001961A (es) | Metodos y sistemas para ensayos. | |
MX2019007894A (es) | Composiciones y metodos para detectar el adn tumoral circulante. | |
GB2542576A (en) | Method and kit of detecting the absence of micro-oranisms | |
MX2017006898A (es) | Amplificacion y deteccion de acidos nucleicos en una muestra biologica. | |
MX2017001134A (es) | Composiciones y metodos para la deteccion y analisis de tuberculosis micobacteriana. | |
EP3460454A4 (en) | BIOSENSOR AND METHOD OF ANALYZING A SPECIMEN USING THE BIOSENSOR | |
EP3147371A4 (en) | Novel method for detecting detection object in sample, and detection kit using same | |
BR112016024622A2 (pt) | composições e métodos para melhorar e/ou prever a amplificação de dna | |
MX2016017136A (es) | Composiciones y metodos para detectar pegivirus 2 de humano (hpgv-2). | |
PL403996A1 (pl) | Sposób jednoczesnej detekcji bakterii i grzybów w preparacie biologicznym metodą PCR, startery oraz zestaw do detekcji bakterii i grzybów |