EP3287791A4 - Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein - Google Patents

Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein Download PDF

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Publication number
EP3287791A4
EP3287791A4 EP16782966.2A EP16782966A EP3287791A4 EP 3287791 A4 EP3287791 A4 EP 3287791A4 EP 16782966 A EP16782966 A EP 16782966A EP 3287791 A4 EP3287791 A4 EP 3287791A4
Authority
EP
European Patent Office
Prior art keywords
reagent
blood specimen
coagulation ability
evaluating coagulation
reagent kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16782966.2A
Other languages
German (de)
French (fr)
Other versions
EP3287791A1 (en
Inventor
Midori Shima
Keiji Nogami
Tomoko Matsumoto
Takehisa Kitazawa
Tetsuhiro Soeda
Yuka Ikeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Sysmex Corp
Nara Medical University PUC
Original Assignee
Chugai Pharmaceutical Co Ltd
Sysmex Corp
Nara Medical University PUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Sysmex Corp, Nara Medical University PUC filed Critical Chugai Pharmaceutical Co Ltd
Publication of EP3287791A1 publication Critical patent/EP3287791A1/en
Publication of EP3287791A4 publication Critical patent/EP3287791A4/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/122—Kinetic analysis; determining reaction rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
EP16782966.2A 2015-04-24 2016-03-30 Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein Pending EP3287791A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015089865 2015-04-24
PCT/JP2016/060566 WO2016170944A1 (en) 2015-04-24 2016-03-30 Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein

Publications (2)

Publication Number Publication Date
EP3287791A1 EP3287791A1 (en) 2018-02-28
EP3287791A4 true EP3287791A4 (en) 2019-03-27

Family

ID=57143474

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16782966.2A Pending EP3287791A4 (en) 2015-04-24 2016-03-30 Method for evaluating coagulation ability of blood specimen, and reagent, reagent kit and device to be used therein

Country Status (5)

Country Link
US (1) US10302626B2 (en)
EP (1) EP3287791A4 (en)
JP (2) JP6147945B2 (en)
CN (2) CN107533071A (en)
WO (1) WO2016170944A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7370322B2 (en) * 2018-06-04 2023-10-27 中外製薬株式会社 How to detect complexes
JP7328251B2 (en) * 2018-11-15 2023-08-16 積水メディカル株式会社 Analysis method, analysis device and analysis program
WO2020158948A1 (en) 2019-01-31 2020-08-06 積水メディカル株式会社 Method for analyzing blood coagulation characteristics of blood specimen
WO2020218425A1 (en) 2019-04-26 2020-10-29 積水メディカル株式会社 Method for measuring titer of coagulation factor inhibitor
CN110160980B (en) * 2019-06-25 2021-12-28 迈克医疗电子有限公司 Method and device for analyzing sample absorbance change rate and optical detection system
CN114829943A (en) * 2019-12-26 2022-07-29 积水医疗株式会社 Method for measuring blood coagulation time
JP2021156833A (en) * 2020-03-30 2021-10-07 シスメックス株式会社 Measuring method of blood coagulation activity
WO2022054819A1 (en) 2020-09-08 2022-03-17 積水メディカル株式会社 Blood coagulation reaction analysis method
JP2022145224A (en) * 2021-03-19 2022-10-03 シスメックス株式会社 Analysis method, analysis device, analysis system, and analysis program for analyzing bleeding tendency of subject
WO2024018789A1 (en) * 2022-07-21 2024-01-25 株式会社日立ハイテク Method for estimating cause of prolongation of blood coagulation time, and information processing device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2775292A1 (en) * 2013-03-06 2014-09-10 Sysmex Corporation Blood coagulation analyzer and blood coagulation analyzing method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004191320A (en) * 2002-12-13 2004-07-08 Sysmex Corp Inspection method of aptt measuring reagent
DE102005008066A1 (en) * 2005-02-22 2006-08-24 Haemosys Gmbh Determining overall coagulation activity of blood or plasma sample, by determining consumed quantity of thrombin inhibitor admixed with blood sample
JP5029638B2 (en) * 2009-03-18 2012-09-19 株式会社島津製作所 Blood coagulation analyzer
JP5455847B2 (en) * 2010-08-27 2014-03-26 京セラ株式会社 Character input device, character input method, and character input program
EP2644698B1 (en) * 2010-11-17 2018-01-03 Chugai Seiyaku Kabushiki Kaisha Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii
JP5607593B2 (en) * 2011-09-05 2014-10-15 日本電信電話株式会社 Coagulation activity measuring device, measuring chip and measuring method
CA2886326C (en) * 2012-09-28 2021-11-02 Chugai Seiyaku Kabushiki Kaisha Method for evaluating blood coagulation reaction
JP2014190954A (en) 2013-03-28 2014-10-06 Sysmex Corp Reagent for activated partial thromboplastin time measurement and usage thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2775292A1 (en) * 2013-03-06 2014-09-10 Sysmex Corporation Blood coagulation analyzer and blood coagulation analyzing method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATSUMOTO TOMOKO ET AL: "A modified thrombin generation test for investigating very low levels of factor VIII activity in hemophilia A", INTERNATIONAL JOURNAL OF HEMATOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 90, no. 5, 25 November 2009 (2009-11-25), pages 576 - 582, XP036412424, ISSN: 0925-5710, [retrieved on 20091125], DOI: 10.1007/S12185-009-0450-Y *
See also references of WO2016170944A1 *

Also Published As

Publication number Publication date
JP2017106925A (en) 2017-06-15
JPWO2016170944A1 (en) 2017-05-18
EP3287791A1 (en) 2018-02-28
WO2016170944A1 (en) 2016-10-27
US20180045709A1 (en) 2018-02-15
CN114578068A (en) 2022-06-03
CN107533071A (en) 2018-01-02
JP6147945B2 (en) 2017-06-14
JP6154969B2 (en) 2017-06-28
US10302626B2 (en) 2019-05-28

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