EA201792155A1 - Композиции и способы детектирования биологического загрязнителя - Google Patents

Композиции и способы детектирования биологического загрязнителя

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Publication number
EA201792155A1
EA201792155A1 EA201792155A EA201792155A EA201792155A1 EA 201792155 A1 EA201792155 A1 EA 201792155A1 EA 201792155 A EA201792155 A EA 201792155A EA 201792155 A EA201792155 A EA 201792155A EA 201792155 A1 EA201792155 A1 EA 201792155A1
Authority
EA
Eurasian Patent Office
Prior art keywords
detection
compositions
methods
biological pollutant
amplification
Prior art date
Application number
EA201792155A
Other languages
English (en)
Other versions
EA037740B1 (ru
Inventor
Сердж Монпехо
Шелдон Минк
Пол Вескио
Original Assignee
Ридженерон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56297073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201792155(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ридженерон Фармасьютикалз, Инк. filed Critical Ридженерон Фармасьютикалз, Инк.
Publication of EA201792155A1 publication Critical patent/EA201792155A1/ru
Publication of EA037740B1 publication Critical patent/EA037740B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Представлены композиции и способы, пригодные для определения того, присутствует ли микробный загрязнитель в процессе производства биологических терапевтических средств. Конкретно, представлены искусственная плазмида позитивного контроля амплификации и оригинальный зонд для количественной полимеразной цепной реакции (PCR), которые делают возможным быстрое детектирование и детектирование в реальном времени ложно позитивных результатов.
EA201792155A 2015-03-27 2016-03-25 Композиции и способы детектирования биологического загрязнителя EA037740B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562139321P 2015-03-27 2015-03-27
PCT/US2016/024216 WO2016160572A1 (en) 2015-03-27 2016-03-25 Compositions and methods for detecting a biological contaminant

Publications (2)

Publication Number Publication Date
EA201792155A1 true EA201792155A1 (ru) 2018-04-30
EA037740B1 EA037740B1 (ru) 2021-05-17

Family

ID=56297073

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201792155A EA037740B1 (ru) 2015-03-27 2016-03-25 Композиции и способы детектирования биологического загрязнителя
EA202190319A EA202190319A1 (ru) 2015-03-27 2016-03-25 Композиции и способы детектирования биологического загрязнителя

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA202190319A EA202190319A1 (ru) 2015-03-27 2016-03-25 Композиции и способы детектирования биологического загрязнителя

Country Status (19)

Country Link
US (3) US10669594B2 (ru)
EP (3) EP3274469B1 (ru)
JP (4) JP6670847B2 (ru)
KR (2) KR102662675B1 (ru)
CN (2) CN107960108B (ru)
AR (2) AR104110A1 (ru)
AU (2) AU2016243498B2 (ru)
CA (2) CA2980915C (ru)
DK (1) DK3274469T3 (ru)
EA (2) EA037740B1 (ru)
ES (1) ES2804845T3 (ru)
IL (4) IL302434A (ru)
MX (2) MX2017012437A (ru)
PL (1) PL3274469T3 (ru)
PT (1) PT3274469T (ru)
SG (2) SG11201707690QA (ru)
TW (3) TW202336236A (ru)
WO (1) WO2016160572A1 (ru)
ZA (2) ZA201706797B (ru)

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TW202336236A (zh) 2015-03-27 2023-09-16 美商再生元醫藥公司 偵測生物污染物之組成物及方法
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US20190093149A1 (en) * 2017-09-27 2019-03-28 The United States Of America, As Represented By The Secretary Of Agriculture Assays for detecting multiple tick-borne pathogens
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US11702653B2 (en) 2018-05-21 2023-07-18 Battelle Memorial Institute Control compositions and methods for sequencing
WO2020124003A1 (en) * 2018-12-13 2020-06-18 Battelle Memorial Institute Methods and control compositions for a quantitative polymerase chain reaction
KR102278112B1 (ko) * 2020-07-10 2021-07-15 (주)하임바이오텍 특정 인공 뉴클레오타이드 서열을 이용한 위양성 판단용 조성물 및 이를 이용한 위양성 판단 방법
KR102532614B1 (ko) * 2020-09-18 2023-05-16 한국식품연구원 가공식품 및 농산물의 설치류 오염여부를 판별하는 방법
JP2023554350A (ja) * 2020-12-17 2023-12-27 アムジエン・インコーポレーテツド ウシパルボウイルス３（Ｂｏｖｉｎｅ ｐａｒｖｏｖｉｒｕｓ ３）を検出するためのリアルタイムＰＣＲ方法
KR102703684B1 (ko) * 2021-07-13 2024-09-04 재단법인 바이오나노헬스가드연구단 미생물 현장 오염 검출용 조성물 및 이의 용도
CN114561492A (zh) * 2022-02-28 2022-05-31 宁夏回族自治区疾病预防控制中心(宁夏回族自治区性病艾滋病防治中心) 一种新冠病毒核酸检测阳性质控品及其制备方法和用途
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Also Published As

Publication number Publication date
EP3274469B1 (en) 2020-04-29
BR112017020582A2 (pt) 2018-07-17
KR102662675B1 (ko) 2024-05-03
AR104110A1 (es) 2017-06-28
KR20240063188A (ko) 2024-05-09
CN114875175A (zh) 2022-08-09
TWI735433B (zh) 2021-08-11
MX2017012437A (es) 2018-06-19
TW202140801A (zh) 2021-11-01
EP3699298B1 (en) 2024-04-24
IL254731B (en) 2021-04-29
ES2804845T3 (es) 2021-02-09
DK3274469T3 (da) 2020-06-15
MX2021007667A (es) 2021-08-05
EP3699298A1 (en) 2020-08-26
EA202190319A1 (ru) 2021-09-30
EP4361290A2 (en) 2024-05-01
US10669594B2 (en) 2020-06-02
SG11201707690QA (en) 2017-10-30
TWI804917B (zh) 2023-06-11
US20200248278A1 (en) 2020-08-06
PT3274469T (pt) 2020-05-29
ZA201806101B (en) 2020-12-23
AR119878A2 (es) 2022-01-19
IL289447A (en) 2022-02-01
CA2980915A1 (en) 2016-10-06
US20230295747A1 (en) 2023-09-21
TW202336236A (zh) 2023-09-16
PL3274469T3 (pl) 2020-10-05
JP2023184743A (ja) 2023-12-28
US20160281182A1 (en) 2016-09-29
EA037740B1 (ru) 2021-05-17
CN107960108B (zh) 2022-03-08
IL281579A (en) 2021-05-31
SG10202006108RA (en) 2020-08-28
JP2020103306A (ja) 2020-07-09
IL254731A0 (en) 2017-11-30
US11549154B2 (en) 2023-01-10
EP3274469A1 (en) 2018-01-31
JP2018509174A (ja) 2018-04-05
IL302434A (en) 2023-06-01
JP2021121226A (ja) 2021-08-26
IL281579B (en) 2022-02-01
JP7385623B2 (ja) 2023-11-22
EP4361290A3 (en) 2024-07-24
TW201706413A (zh) 2017-02-16
CA2980915C (en) 2024-02-27
CA3226784A1 (en) 2016-10-06
CN107960108A (zh) 2018-04-24
KR20180026661A (ko) 2018-03-13
ZA201706797B (en) 2020-01-29
WO2016160572A1 (en) 2016-10-06
AU2016243498B2 (en) 2022-07-07
AU2022246398A1 (en) 2022-11-03
JP6894026B2 (ja) 2021-06-23
JP6670847B2 (ja) 2020-03-25
AU2016243498A1 (en) 2017-10-26
AU2016243498A2 (en) 2018-04-19

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