AR118194A1 - Derivados heterociclos bicíclicos condensados como plaguicida - Google Patents

Derivados heterociclos bicíclicos condensados como plaguicida

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Publication number
AR118194A1
AR118194A1 ARP200100522A ARP200100522A AR118194A1 AR 118194 A1 AR118194 A1 AR 118194A1 AR P200100522 A ARP200100522 A AR P200100522A AR P200100522 A ARP200100522 A AR P200100522A AR 118194 A1 AR118194 A1 AR 118194A1
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AR
Argentina
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6alkyl
6alkoxy
6haloalkyl
halogen
cycloalkyl
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ARP200100522A
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English (en)
Inventor
Ilg Kerstin Dr
Hager Dominik Dr
Fischer Rdiger Dr
Sergey Zhersh
Lsel Peter Dr
Willot Matthieu Dr
Hoffmeister Laura Dr
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Bayer Ag
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Publication of AR118194A1 publication Critical patent/AR118194A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Reivindicación 1: Compuestos de la fórmula (1) caracterizada porque Aa significa nitrógeno o =C(R⁷)-, Ab significa nitrógeno o =C(R⁸)-, Ac significa nitrógeno o =C(R⁹)-, Ad significa nitrógeno o =C(R¹⁰)-, Ae significa nitrógeno o =C(R¹¹), a lo cual, Ab, Ac, Ad y Ae no pueden representar simultáneamente nitrógeno, R¹ significa C₁₋₆alquilo, C₁₋₆halógenoalquilo, C₁₋₆alquenilo, C₂₋₆halógenoalquenilo, C₂₋₆alquinilo, C₂₋₆halógenoalquinilo, C₃₋₈cicloalquilo, halógenoC₃₋₈cicloalquilo, C₃₋₆cicloalquilo-C₁₋₆alquilo, C₃₋₆cicloalquilo-C₁₋₆halógenoalquilo, C₁₋₆alquilo-C₃₋₈cicloalquilo, C₁₋₆halógenoalquilo-C₃₋₈cicloalquilo, C₃₋₈cicloalquilo-C₃₋₈cicloalquilo, espiro-C₃₋₈cicloalquilo-C₃₋₈cicloalquilo, C₄₋₁₂bicicloalquilo, C₁₋₆cianoalquilo, C₁₋₆hidroxialquilo, C₁₋₆alcoxi-C₁₋₆alquilo, C₂₋₆cianoalquenilo, C₃₋₆cicloalquilo-C₂₋₆alquenilo, C₂₋₆cianoalquinilo, C₃₋₆cicloalquilo-C₂₋₆alquinilo, C₁₋₆halógenoalcoxi-C₁₋₆alquilo, C₂₋₆alqueniloxi-C₁₋₆alquilo, C₂₋₆halógenoalqueniloxi-C₁₋₆alquilo, C₂₋₆alquiniloxi-C₁₋₄alquilo, C₂₋₆halógenoalquiniloxi-C₁₋₆alquilo, C₁₋₆alquiltio-C₁₋₆alquilo, C₁₋₆alquilosulfinilo-C₁₋₆alquilo, C₁₋₆alquilosulfonilo-C₁₋₆alquilo, C₁₋₆halógenoalquiltio-C₁₋₆alquilo, C₁₋₆halógenoalquilosulfinilo-C₁₋₆alquilo, C₁₋₆halógenoalquilosulfonilo-C₁₋₆alquilo, o tri-C₁₋₆alquilsililo, R⁷ significa hidrógeno, ciano, halógeno, acetilo, hidroxi, amino, C₃₋₈cicloalquilo, halógenoC₃₋₈cicloalquilo, C₁₋₆alquilo, C₁₋₆haloalquilo, C₁₋₆cianoalquilo, C₂₋₆alquenilo, C₂₋₆haloalquenilo, C₂₋₆alquinilo, C₂₋₆haloalquinilo, C₁₋₆alcoxi, C₁₋₆haloalcoxi, C₁₋₆alquiltio, C₁₋₆halógenoalquiltio, C₁₋₆alquilsulfinilo, C₁₋₆haloalquilsulfinilo, C₁₋₆alquilsulfonilo o C₁₋₆haloalquilsulfonilo, R⁸, R⁹, R¹⁰, R¹¹ independientemente uno del otro significan hidrógeno, halógeno, C₁₋₆alquilo, C₁₋₆haloalquilo, C₁₋₆alcoxi, C₁₋₆haloalcoxi, C₁₋₆haloalquiltio, C₁₋₆haloalquilsulfinilo, C₁₋₆haloalquilsulfonilo o C₁₋₆halógenoalquilo-C₃₋₈cicloalquilo, dado el caso, C₁₋₆cianoalquilo mono o polisustituido por halógeno, C₁₋₆cianoalquilo-C₃₋₈cicloalquilo, C₁₋₆halógenoalquilo-C₃₋₈cianocicloalquilo, C₁₋₆halógenoalquilo-C₃₋₈halógenocicloalquilo, dado el caso cianoC₃₋₆cicloalquilo mono o polisustituido por C₁₋₆alquilo o halógeno, dado el caso, espiro-C₃₋₈cicloalquilo-C₃₋₈cicloalquilo mono o polisustituido por ciano o halógeno, respectivamente o C₄₋₁₂bicicloalquilo, donde uno de los radicales R⁸, R⁹, R¹⁰, R¹¹ debe seleccionarse de C₁₋₆haloalquilo-C₃₋₈cicloalquilo, C₁₋₆cianoalquilo-C₃₋₈cicloalquilo, C₁₋₆haloalquilo-C₃₋₈cianocicloalquilo C₃₋₈, C₁₋₆haloalquilo-C₃₋₈halocicloalquilo, opcionalmente sustituido de forma simple o múltiple con C₁₋₆alquilo o cianoC₃₋₆cicloalquilo sustituido con halógeno, cada uno opcionalmente sustituido de forma simple o múltiple con ciano o espiro-C₃₋₈cicloalquilo-C₃₋₈cicloalquilo sustituido con halógeno o C₄₋₁₂bicicloalquilo, donde solo uno o dos de los radicales R⁸, R⁹, R¹⁰ o R¹¹ representa un sustituyente no igual a hidrógeno, Q se refiere a un compuesto cíclico parcialmente saturado o a un compuesto cíclico saturado heterocíclico o heteroaromático, bicíclico o tricíclico condensado de 8, 9, 10, 11 ó 12 eslabones que, dado el caso, puede contener al menos un grupo de carbonilo y/o el compuesto cíclico, dado el caso, es mono o polisustituido, de manera igual o diversa, y en donde los sustituyentes pueden elegirse independientemente entre sí entre hidrógeno, ciano, halógeno, nitro, acetilo, hidroxi, amino, SCN, tri-C₁₋₆alquilsilil, C₃₋₈cicloalquilo, C₃₋₈cicloalquilo-C₃₋₈cicloalquilo, C₁₋₆alquilo-C₃₋₈cicloalquilo, halógenoC₃₋₈cicloalquilo, C₁₋₆alquilo, C₁₋₆halógenoalquilo, C₁₋₆cianoalquilo, C₁₋₆hidroxialquilo, hidroxicarbonilo-C₁₋₆alcoxi, C₁₋₆alcoxicarbonilo-C₁₋₆alquilo, C₁₋₆alcoxi-C₁₋₆alquilo, C₂₋₆alquenilo, C₂₋₆halógenoalquenilo, C₂₋₆cianoalquenilo, C₂₋₆alquinilo, C₂₋₆alquiniloxi-C₁₋₄alquilo, C₂₋₆halógenoalquinilo, C₂₋₆cianoalquinilo, C₁₋₆alcoxi, C₁₋₆halógenoalcoxi, C₁₋₆halógenoalcoxi-C₁₋₆alquilo, C₂₋₆alqueniloxi-C₁₋₆alquilo, C₂₋₆halógenoalqueniloxi-C₁₋₆alquilo, C₁₋₆cianoalcoxi, C₁₋₆alcoxicarbonilo-C₁₋₆alcoxi, C₁₋₆alcoxi-C₁₋₆alcoxi, C₁₋₆alquilo-hidroxiimino, C₁₋₆alcoxiimino, C₁₋₆alquilo-C₁₋₆alcoxiimino, C₁₋₆halógenoalquilo-C₁₋₆alcoxiimino, C₁₋₆alquiltio, C₁₋₆halógenoalquiltio, C₁₋₆alcoxi-C₁₋₆alquiltio, C₁₋₆alquiltio-C₁₋₆alquilo, C₁₋₆alquilosulfinilo, C₁₋₆halógenoalquilosulfinilo, C₁₋₆alcoxi-C₁₋₆alquilosulfinilo, C₁₋₆alquilosulfinilo-C₁₋₆alquilo, C₁₋₆alquilosulfonilo, C₁₋₆halógenoalquilosulfonilo, C₁₋₆alcoxi-C₁₋₆alquilosulfonilo, C₁₋₆alquilosulfonilo-C₁₋₆alquilo, C₁₋₆alquilosulfoniloxi, C₁₋₆alquilocarbonilo, C₁₋₆alquilocarbonilo-C₁₋₆alquilo, C₁₋₆alquiltio-carbonilo, C₁₋₆halógenoalcoxicarbonilo, C₁₋₆alquilocarboniloxi, C₁₋₆alcoxicarbonilo, C₁₋₆halógenoalcoxicarbonilo, aminocarbonilo, C₁₋₆alquiloaminocarbonilo, C₁₋₆alquiloaminotiocarbonilo, di-C₁₋₆alquilo-aminocarbonilo, di-C₁₋₆alquilo-aminotiocarbonilo, C₂₋₆alquenilo-aminocarbonilo, di-C₂₋₆-alquenilo-aminocarbonilo, C₃₋₈cicloalquilo-aminocarbonilo, C₁₋₆alquilo-sulfonilamino, C₁₋₆alquilamino, di-C₁₋₆alquilamino, aminosulfonilo, C₁₋₆alquilo-aminosulfonilo, di-C₁₋₆alquilo-aminosulfonilo, C₁₋₆alquilo-sulfoximino, aminotiocarbonilo, C₁₋₆alquilo-aminotiocarbonilo, di-C₁₋₆alquilo-aminotiocarbonilo, C₃₋₈cicloalquilamino, NHCO-C₁₋₆alquilo(C₁₋₆alquilocarbonilamino), o donde los sustituyentes pueden elegirse independientemente entre sí entre fenil o un compuesto heteroaromático de 5 ó 6 anillos, mientras que el fenil o el compuesto pueden ser mono o polisustituidos, de manera igual o diversa por C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₆-cicloalquilo, C₁₋₆-haloalquilo, C₂₋₆-haloalquenilo, C₂₋₆-haloalquinilo, C₃₋₆-halocicloalquilo, halógeno, CN, NO₂, C₁₋₄-alcoxi, C₁₋₄-haloalcoxi, n significa 0, 1 ó 2.
ARP200100522A 2019-02-26 2020-02-26 Derivados heterociclos bicíclicos condensados como plaguicida AR118194A1 (es)

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EP (1) EP3931192B1 (es)
JP (1) JP7535532B2 (es)
KR (1) KR20210133984A (es)
CN (1) CN113727983A (es)
AR (1) AR118194A1 (es)
AU (1) AU2020228119A1 (es)
BR (1) BR112021010400A2 (es)
CL (1) CL2021002251A1 (es)
CO (1) CO2021011038A2 (es)
ES (1) ES2980245T3 (es)
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