AR110133A1 - Sulfonilamidas sustituidas para combatir parásitos animales - Google Patents

Sulfonilamidas sustituidas para combatir parásitos animales

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Publication number
AR110133A1
AR110133A1 ARP170103079A ARP170103079A AR110133A1 AR 110133 A1 AR110133 A1 AR 110133A1 AR P170103079 A ARP170103079 A AR P170103079A AR P170103079 A ARP170103079 A AR P170103079A AR 110133 A1 AR110133 A1 AR 110133A1
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AR
Argentina
Prior art keywords
alkyl
alkoxy
halogen
cycloalkyl
alkylsulfinyl
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Application number
ARP170103079A
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English (en)
Inventor
Turberg Andreas Dr
Lishchynskyi Anton Dr
Ulrich Grgens
Arnd Voerste
Becker Angela Dr
Herrmann Stefan Dr
Lsel Peter Dr
Eilmus Sascha Dr
Malsam Olga Dr
Ilg Kerstin Dr
Portz Daniela Dr
Schwarz Hans Dr
- Dr Jansen Johannes Georg
- Dr Andree Roland Rudolf
Kausch-Busies Nina Dr
Hager Dominik Dr
Kbbeler Susanne Dr
Wroblowsky Heinz Dr
- Dr Flein Martin Juergen
Original Assignee
Bayer Ag
Bayer Cropscience Ag
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Application filed by Bayer Ag, Bayer Cropscience Ag filed Critical Bayer Ag
Publication of AR110133A1 publication Critical patent/AR110133A1/es

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Toxicology (AREA)

Abstract

La presente se refiere al uso de un compuesto de la fórmula general (1), para combatir parásitos animales, en particular nematodos. Reivindicación 1: Uso de un compuesto de la fórmula (1), en la que M representa un resto seleccionado de las fórmulas (2) - (4), donde R¹ es hidrógeno, hidroxi, ciano, carboxi, halógeno, nitro, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, halógenoalquiltio C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, alquiltiocarbonilo C₁₋₆, alquilsulfoximino C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquil C₁₋₆-aminosulfonilo, halógenoalquiltio C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆-alquilo C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquilamino C₃₋₈, alquilcarbonilamino C₁₋₆ o es aril-alquilo C₁₋₆ o hetaril-alquilo C₁₋₆ dado el caso mono- o polisustituido de manera igual o diferente, donde en el caso de hetarilo, eventualmente puede estar contenido al menos un grupo carbonilo y donde el o los sustituyentes se seleccionaron en cada caso independientemente entre sí de: ciano, carboxilo, halógeno, nitro, acetilo, hidroxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquilhidroxiimino C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquilaminsulfonilo C₁₋₆, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquilaminotiocarbonilo C₁₋₆, cicloalquilamino C₃₋₈ y/o alquilcarbonilamino C₁₋₆; R² es hidrógeno, ciano, halógeno, nitro, acetilo, hidroxi, carboxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, halógenoalquiltio C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, alquiltiocarbonilo C₁₋₆, alquilsulfoximino C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquil C₁₋₆-aminosulfonilo, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquilamino C₃₋₈, alquilcarbonilamino C₁₋₆ o es arilo o hetarilo dado el caso mono- o polisustituido de manera igual o diferente, donde en el caso de hetarilo, eventualmente puede estar contenido al menos un grupo carbonilo y donde como sustituyentes se consideran respectivamente: ciano, carboxilo, halógeno, nitro, acetilo, hidroxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquilhidroxiimino C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquilaminsulfonilo C₁₋₆, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquilaminotiocarbonilo C₁₋₆, cicloalquilamino C₃₋₈ y/o alquilcarbonilamino C₁₋₆; R³ es hidrógeno, ciano, halógeno, hidroxi, carboxi, nitro, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, halógenoalquiltio C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, alquiltiocarbonilo C₁₋₆, alquilsulfoximino C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquil C₁₋₆-aminosulfonilo, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquilamino C₃₋₈, alquilcarbonilamino C₁₋₆ o es aril-alquilo C₁₋₆ o hetaril-alquilo C₁₋₆ dado el caso mono- o polisustituido de manera igual o diferente, donde en el caso de hetarilo, eventualmente puede estar contenido al menos un grupo carbonilo y donde el o los sustituyentes se seleccionaron en cada caso independientemente entre sí de: ciano, carboxilo, halógeno, nitro, acetilo, hidroxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquilhidroxiimino C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquilaminsulfonilo C₁₋₆, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquilaminotiocarbonilo C₁₋₆, cicloalquilamino C₃₋₈ y/o alquilcarbonilamino C₁₋₆; R⁴ es hidrógeno, ciano, halógeno, nitro, acetilo, hidroxi, carboxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alquilsulfoximino C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquiltio C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆-alquilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, alquiltiocarbonilo C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, di-alquil C₁₋₆-aminotiocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquil C₁₋₆-aminosulfonilo, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquil C₁₋₆-aminotiocarbonilo, cicloalquilamino C₃₋₈, alquilcarbonilamino C₁₋₆ o es arilo o hetarilo dado el caso mono- o polisustituido de manera igual o diferente, donde en el caso de hetarilo, eventualmente puede estar contenido al menos un grupo carbonilo y donde como sustituyentes se consideran respectivamente: ciano, carboxilo, halógeno, nitro, acetilo, hidroxi, amino, SCN, tri-alquilsililo C₁₋₆, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, hidroxicarbonil-alcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alquilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₆, alquenilo C₂₋₆, halógenoalquenilo C₂₋₆, cianoalquenilo C₂₋₆, alquinilo C₂₋₆, halógenoalquinilo C₂₋₆, cianoalquinilo C₂₋₆, alcoxi C₁₋₆, halógenoalcoxi C₁₋₆, cianoalcoxi C₁₋₆, alcoxicarbonil C₁₋₆-alcoxi C₁₋₆, alcoxi C₁₋₆-alcoxi C₁₋₆, alquilhidroxiimino C₁₋₆, alcoxiimino C₁₋₆, alquil C₁₋₆-alcoxiimino C₁₋₆, halógenoalquilo C₁₋₆-alcoxiimino C₁₋₆, alquiltio C₁₋₆, halógenoalquiltio C₁₋₆, alcoxi C₁₋₆-alquiltio C₁₋₆, alquiltio C₁₋₆-alquilo C₁₋₆, alquilsulfinilo C₁₋₆, halógenoalquilsulfinilo C₁₋₆, alcoxi C₁₋₆-alquilsulfinilo C₁₋₆, alquilsulfinilo C₁₋₆-alquilo C₁₋₆, alquilsulfonilo C₁₋₆, halógenoalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilsulfonilo C₁₋₆, alquilsulfonilo C₁₋₆-alquilo C₁₋₆, alquilsulfoniloxi C₁₋₆, alquilcarbonilo C₁₋₆, halógenoalquilcarbonilo C₁₋₆, alquilcarboniloxi C₁₋₆, alcoxicarbonilo C₁₋₆, halógenoalcoxicarbonilo C₁₋₆, aminocarbonilo, alquilaminocarbonilo C₁₋₆, di-alquil C₁₋₆-aminocarbonilo, alquenilaminocarbonilo C₂₋₆, di-alquenilaminocarbonilo C₂₋₆, cicloalquilaminocarbonilo C₃₋₈, alquilsulfonilamino C₁₋₆, alquilamino C₁₋₆, di-alquilamino C₁₋₆, aminosulfonilo, alquilaminsulfonilo C₁₋₆, di-alquilaminsulfonilo C₁₋₆, alquilsulfoximino C₁₋₆, aminotiocarbonilo, alquilaminotiocarbonilo C₁₋₆, di-alquilaminotiocarbonilo C₁₋₆, cicloalquilamino C₃₋₈ y/o alquilcarbonilamino C₁₋₆; R⁵ es hidrógeno, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-cicloalquilo C₃₋₈, alquil C₁₋₆-cicloalquilo C₃₋₈, halógenocicloalquilo C₃₋₈, alquilo C₁₋₆, halógenoalquilo C₁₋₆, cianoalquilo C₁₋₆, hidroxialquilo C₁₋₆, alcoxicarbonil C₁₋₆-alquilo
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