SG10201705852PA - Pyridine derivative - Google Patents

Pyridine derivative

Info

Publication number
SG10201705852PA
SG10201705852PA SG10201705852PA SG10201705852PA SG10201705852PA SG 10201705852P A SG10201705852P A SG 10201705852PA SG 10201705852P A SG10201705852P A SG 10201705852PA SG 10201705852P A SG10201705852P A SG 10201705852PA SG 10201705852P A SG10201705852P A SG 10201705852PA
Authority
SG
Singapore
Prior art keywords
pyridine derivative
pyridine
derivative
Prior art date
Application number
SG10201705852PA
Inventor
Akinobu Maruyama
Hirofumi Kamada
Mika Fujinuma
Susumu Takeuchi
Hiroshi Saitoh
Yoshimasa Takahashi
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Publication of SG10201705852PA publication Critical patent/SG10201705852PA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Beans For Foods Or Fodder (AREA)
SG10201705852PA 2012-11-14 2013-11-13 Pyridine derivative SG10201705852PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012250661 2012-11-14

Publications (1)

Publication Number Publication Date
SG10201705852PA true SG10201705852PA (en) 2017-08-30

Family

ID=50731196

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201705852PA SG10201705852PA (en) 2012-11-14 2013-11-13 Pyridine derivative
SG11201503770VA SG11201503770VA (en) 2012-11-14 2013-11-13 Pyridine derivative

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201503770VA SG11201503770VA (en) 2012-11-14 2013-11-13 Pyridine derivative

Country Status (36)

Country Link
US (2) US9637469B2 (en)
EP (2) EP3339302A1 (en)
JP (2) JP5774238B2 (en)
KR (1) KR20150082194A (en)
CN (2) CN107721931A (en)
AR (1) AR093468A1 (en)
AU (2) AU2013345894B2 (en)
BR (1) BR112015010977A2 (en)
CA (1) CA2891408A1 (en)
CL (1) CL2015001279A1 (en)
CY (1) CY1120127T1 (en)
DK (1) DK2944633T3 (en)
ES (1) ES2662444T3 (en)
HK (1) HK1211940A1 (en)
HR (1) HRP20180451T1 (en)
HU (1) HUE037736T2 (en)
IL (2) IL238539A (en)
LT (1) LT2944633T (en)
MA (1) MA38078B1 (en)
ME (1) ME03016B (en)
MX (1) MX2015003672A (en)
NO (1) NO2944633T3 (en)
NZ (1) NZ708031A (en)
PE (1) PE20150974A1 (en)
PH (1) PH12015501037A1 (en)
PL (1) PL2944633T3 (en)
PT (1) PT2944633T (en)
RS (1) RS57090B1 (en)
RU (1) RU2640588C2 (en)
SA (1) SA515360431B1 (en)
SG (2) SG10201705852PA (en)
SI (1) SI2944633T1 (en)
TW (1) TWI666205B (en)
UA (1) UA117359C2 (en)
WO (1) WO2014077285A1 (en)
ZA (1) ZA201503322B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2948792A1 (en) * 2014-05-13 2015-11-19 Teijin Pharma Limited Novel crystalline polymorphs of pyridine derivative and method for producing the same
AR100403A1 (en) * 2014-05-13 2016-10-05 Teijin Pharma Ltd PIRAZINE DERIVATIVES
CA3017547A1 (en) * 2016-03-15 2017-09-21 Bayer Cropscience Aktiengesellschaft Substituted sulfonyl amides for controlling animal pests
CN107286156A (en) * 2016-04-05 2017-10-24 江苏新元素医药科技有限公司 New URAT1 inhibitor and its in application pharmaceutically
CN106008488B (en) * 2016-05-20 2018-10-30 广东东阳光药业有限公司 Cyanoindole analog derivative and its preparation method and application
WO2017202291A1 (en) * 2016-05-23 2017-11-30 南京明德新药研发股份有限公司 Thiophene, manufacturing method thereof, and pharmaceutical application of same
TW201822637A (en) 2016-11-07 2018-07-01 德商拜耳廠股份有限公司 Substituted sulfonamides for controlling animal pests
JP7098630B2 (en) 2017-01-10 2022-07-11 バイエル・アクチエンゲゼルシヤフト Heterocyclene derivative as a pest control agent
TW201837036A (en) 2017-01-10 2018-10-16 德商拜耳廠股份有限公司 Heterocycle derivatives as pesticides
CN108658879A (en) * 2017-03-29 2018-10-16 天津药物研究院有限公司 A kind of URAT1 inhibitor and its preparation method and application
CN109251184B (en) * 2017-07-13 2021-06-15 浙江海正药业股份有限公司 Medical application of 2-trifluoromethyl benzene sulfonamide derivative
KR20200142508A (en) 2018-03-08 2020-12-22 인사이트 코포레이션 Aminopyrazine diol compounds as PI3K-γ inhibitors
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
TWI820231B (en) 2018-10-11 2023-11-01 德商拜耳廠股份有限公司 Process for preparing substituted imidazole derivatives
CN111943957B (en) * 2019-05-17 2023-01-06 中国医学科学院药物研究所 Quinoline formamide compound and preparation method and application thereof
EP4055010A1 (en) 2019-11-07 2022-09-14 Bayer Aktiengesellschaft Substituted sulfonyl amides for controlling animal pests
US20230247994A1 (en) 2020-07-02 2023-08-10 Bayer Aktiengesellschaft Heterocyclene derivatives as pest control agents
CN114315729B (en) * 2021-12-09 2024-01-26 大连理工大学 1-benzyl-2, 4-diaryl imidazole compound, synthetic method and application thereof in resisting tumor

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1599032A (en) * 1977-03-04 1981-09-30 May & Baker Ltd Imidazole derivatives having herbicidal activity
JPS5671073A (en) 1979-11-12 1981-06-13 Takeda Chem Ind Ltd Imidazole derivative
US4770689A (en) * 1986-03-10 1988-09-13 Janssen Pharmaceutica N.V. Herbicidal imidazole-5-carboxylic acid derivatives
PL149675B1 (en) * 1986-03-10 1990-03-31 Method of obtaining novel derivatives of 1-methyl 1h-imidazolecarboxylic-5 acid
MY100938A (en) 1986-06-06 1991-05-31 Ciba Geigy Ag Arylkylimidazole derivatives.
DD260928A5 (en) * 1986-06-06 1988-10-12 Ciba-Geigy Ag,Ch PROCESS FOR THE PREPARATION OF NEW ARALKYLIMIDIZOL DERIVATIVES
JPH08119936A (en) * 1994-10-18 1996-05-14 Fujisawa Pharmaceut Co Ltd Heterocyclic derivative
IT1295405B1 (en) * 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P USE OF AN ANGIOTENSIN II RECEPTORAL ANTAGONIST FOR DRUG PREPARATION TO INCREASE THE SURVIVAL RATE OF
AU2001275794A1 (en) * 2000-07-28 2002-02-13 Sumitomo Pharmaceuticals Co. Ltd. Pyrrole derivatives
ATE376830T1 (en) 2001-02-22 2007-11-15 Teijin Pharma Ltd BENZO(B(THIOPHENE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
AU2003902828A0 (en) * 2003-06-05 2003-06-26 Fujisawa Pharmaceutical Co., Ltd. Dpp-iv inhibitor
PT2217577E (en) * 2007-11-27 2014-10-20 Ardea Biosciences Inc Novel compounds and compositions and methods of use
WO2009148599A1 (en) * 2008-06-04 2009-12-10 Synta Pharmaceuticals Corp. Pyrrole compunds that modulate hsp90 activity
BRPI0918586A2 (en) * 2008-09-04 2015-12-01 Ardea Biosciences Inc compounds, compositions and methods of use thereof for modulating uric acid levels
JP2010202575A (en) * 2009-03-03 2010-09-16 Takeda Chem Ind Ltd Heterocyclic compound
CN102548964B (en) * 2009-07-10 2014-09-24 通用医疗公司 Etomidate analogues that do not inhibit adrenocortical steroid synthesis
CN102035579B (en) * 2009-09-28 2014-09-03 夏普株式会社 Information feedback method and user equipment
AR081930A1 (en) 2010-06-16 2012-10-31 Ardea Biosciences Inc THIOACETATE COMPOUNDS
JP5485811B2 (en) * 2010-06-23 2014-05-07 株式会社ジャパンディスプレイ Bidirectional shift register and image display device using the same
CA2807971A1 (en) 2010-08-11 2012-02-16 Millenium Pharmaceuticals, Inc. Heteroaryls and uses thereof

Also Published As

Publication number Publication date
PH12015501037A1 (en) 2015-07-27
WO2014077285A1 (en) 2014-05-22
IL238539A0 (en) 2015-06-30
UA117359C2 (en) 2018-07-25
AR093468A1 (en) 2015-06-10
CA2891408A1 (en) 2014-05-22
ES2662444T3 (en) 2018-04-06
SG11201503770VA (en) 2015-06-29
ME03016B (en) 2018-10-20
NO2944633T3 (en) 2018-06-30
PE20150974A1 (en) 2015-07-04
PT2944633T (en) 2018-05-09
EP3339302A1 (en) 2018-06-27
SA515360431B1 (en) 2017-11-15
NZ708031A (en) 2018-04-27
JP5774238B2 (en) 2015-09-09
JP2015091865A (en) 2015-05-14
PL2944633T3 (en) 2018-08-31
AU2013345894B2 (en) 2017-05-25
ZA201503322B (en) 2016-01-27
US20170190694A1 (en) 2017-07-06
CY1120127T1 (en) 2018-12-12
TWI666205B (en) 2019-07-21
MA38078A1 (en) 2016-09-30
CL2015001279A1 (en) 2015-06-26
CN107721931A (en) 2018-02-23
HRP20180451T1 (en) 2018-06-01
AU2017204665A1 (en) 2017-07-27
US9637469B2 (en) 2017-05-02
KR20150082194A (en) 2015-07-15
BR112015010977A2 (en) 2017-07-11
SI2944633T1 (en) 2018-06-29
JPWO2014077285A1 (en) 2017-01-05
CN104797570A (en) 2015-07-22
LT2944633T (en) 2018-03-12
JP6293068B2 (en) 2018-03-14
DK2944633T3 (en) 2018-03-12
TW201422603A (en) 2014-06-16
AU2013345894A1 (en) 2015-05-21
US20150284358A1 (en) 2015-10-08
CN104797570B (en) 2017-11-07
AU2013345894A9 (en) 2015-11-12
MX2015003672A (en) 2015-06-15
IL238539A (en) 2017-11-30
RU2015122698A (en) 2017-01-10
MA38078B1 (en) 2017-04-28
EP2944633A4 (en) 2016-01-06
HK1211940A1 (en) 2016-06-03
EP2944633B1 (en) 2018-01-31
HUE037736T2 (en) 2018-09-28
RS57090B1 (en) 2018-06-29
EP2944633A1 (en) 2015-11-18
RU2640588C2 (en) 2018-01-10
IL243193A0 (en) 2016-02-29

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