AR092957A1 - Formulacion de forma farmaceutica solida de desintegracion veloz que comprende carbonato de calcio funcionalizado y metodo para su fabricacion - Google Patents
Formulacion de forma farmaceutica solida de desintegracion veloz que comprende carbonato de calcio funcionalizado y metodo para su fabricacionInfo
- Publication number
- AR092957A1 AR092957A1 ARP130103663A ARP130103663A AR092957A1 AR 092957 A1 AR092957 A1 AR 092957A1 AR P130103663 A ARP130103663 A AR P130103663A AR P130103663 A ARP130103663 A AR P130103663A AR 092957 A1 AR092957 A1 AR 092957A1
- Authority
- AR
- Argentina
- Prior art keywords
- speed
- calcium carbonate
- deintegration
- formulation
- manufacturing
- Prior art date
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title abstract 7
- 229910000019 calcium carbonate Inorganic materials 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 4
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 2
- 239000001569 carbon dioxide Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 238000010306 acid treatment Methods 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/006—Pressing and sintering powders, granules or fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/772—Articles characterised by their shape and not otherwise provided for
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Mechanical Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Geology (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Abstract
Una forma farmacéutica de desintegración veloz oral que comprende carbonato de calcio natural o sintético funcionalizado, por lo menos un ingrediente activo y por lo menos un desintegrante, donde dicho carbonato de calcio natural o sintético funcionalizado es un producto de la reacción de carbonato de calcio natural o sintético con dióxido de carbono y uno o más ácidos, donde el dióxido de carbono se forma in situ mediante el tratamiento ácido, y/o es suministrado desde una fuente externa, y donde el comprimido se disuelve en menos de 20 segundos cuando se introduce en un entorno acuoso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12188344.1A EP2719373B1 (en) | 2012-10-12 | 2012-10-12 | Fast disintegrating solid dosage form formulation comprising functionalized calcium carbonate and method of their manufacture |
US201261713671P | 2012-10-15 | 2012-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR092957A1 true AR092957A1 (es) | 2015-05-06 |
Family
ID=47022552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130103663A AR092957A1 (es) | 2012-10-12 | 2013-10-09 | Formulacion de forma farmaceutica solida de desintegracion veloz que comprende carbonato de calcio funcionalizado y metodo para su fabricacion |
Country Status (27)
Country | Link |
---|---|
US (1) | US20150283082A1 (es) |
EP (2) | EP2719373B1 (es) |
JP (1) | JP6196676B2 (es) |
KR (1) | KR101740835B1 (es) |
CN (2) | CN104768531A (es) |
AR (1) | AR092957A1 (es) |
AU (1) | AU2013328639B2 (es) |
BR (1) | BR112015008139B1 (es) |
CA (1) | CA2884912C (es) |
CL (1) | CL2015000893A1 (es) |
CO (1) | CO7350657A2 (es) |
DK (2) | DK2719373T3 (es) |
ES (2) | ES2628371T3 (es) |
HR (1) | HRP20191082T1 (es) |
HU (1) | HUE044281T2 (es) |
IL (1) | IL237766B (es) |
MX (1) | MX369779B (es) |
MY (1) | MY174635A (es) |
PL (2) | PL2719373T3 (es) |
PT (1) | PT2916816T (es) |
RU (2) | RU2018127317A (es) |
SG (1) | SG11201502290SA (es) |
SI (2) | SI2719373T1 (es) |
TR (1) | TR201909173T4 (es) |
TW (1) | TWI583387B (es) |
UY (1) | UY35071A (es) |
WO (1) | WO2014057038A1 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2654577T5 (es) | 2013-12-13 | 2021-06-17 | Omya Int Ag | Composición limpiadora abrasiva |
CA2937049C (en) | 2013-12-16 | 2024-01-16 | The University Of British Columbia | Self-fueled particles for propulsion through flowing aqueous fluids |
EP2921173A1 (en) | 2014-03-21 | 2015-09-23 | Omya International AG | Surface-reacted calcium carbonate for desensitizing teeth |
EP2949708B1 (en) | 2014-05-30 | 2018-04-04 | Omya International AG | Method for the production of granules comprising surface-reacted calcium carbonate |
TWI565763B (zh) | 2014-05-30 | 2017-01-11 | 歐米亞國際公司 | 製造包含表面經反應碳酸鈣之顆粒的方法 |
EP2957603A1 (en) | 2014-06-20 | 2015-12-23 | Omya International AG | Method for the production of granules comprising surface-reacted calcium carbonate |
EP3034070A1 (en) | 2014-12-18 | 2016-06-22 | Omya International AG | Method for the production of a pharmaceutical delivery system |
EP3069713A1 (en) | 2015-03-20 | 2016-09-21 | Omya International AG | Dispersible dosage form |
EP3176222A1 (en) * | 2015-12-01 | 2017-06-07 | Omya International AG | Method for the production of granules comprising surface-reacted calcium carbonate |
EP3260115A1 (en) * | 2016-06-21 | 2017-12-27 | Omya International AG | Method for the production of a dosage form |
EP3260114A1 (en) * | 2016-06-21 | 2017-12-27 | Omya International AG | Method for the production of a dosage form |
EP3269361A1 (en) | 2016-07-14 | 2018-01-17 | Omya International AG | Dosage form |
EP3275946A1 (en) * | 2016-07-25 | 2018-01-31 | Omya International AG | Post treatment of surface-reacted calcium carbonate with different functional cations |
EP3275537A1 (en) * | 2016-07-25 | 2018-01-31 | Omya International AG | Surface-modified calcium carbonate as carrier for transition metal-based catalysts |
EP3594289A1 (en) * | 2018-07-13 | 2020-01-15 | Omya International AG | Surface-reacted calcium carbonate for stabilizing mint oil |
CN118593436A (zh) * | 2018-09-17 | 2024-09-06 | Omya国际股份公司 | 包含共加工的微晶纤维素和经表面反应碳酸钙的高性能赋形剂 |
EP3682901A1 (en) | 2019-01-21 | 2020-07-22 | Omya International AG | High performance excipient comprising co-processed microcrystalline cellulose and surface-reacted calcium carbonate |
EP3622966A1 (en) | 2018-09-17 | 2020-03-18 | Omya International AG | High performance excipient comprising co-processed microcrystalline cellulose and surface-reacted calcium carbonate |
CN109749745A (zh) * | 2018-12-21 | 2019-05-14 | 西北农林科技大学 | 一种利用土体固化溶液加固土体的方法 |
US11113797B1 (en) | 2019-08-19 | 2021-09-07 | Snap Inc. | Passive flash imaging |
WO2021219529A1 (en) | 2020-04-28 | 2021-11-04 | Omya International Ag | Method for the production of free-flowing granules |
TW202200206A (zh) | 2020-04-28 | 2022-01-01 | 瑞士商歐米亞國際公司 | 包含表面反應碳酸鈣作為賦形劑之顆粒 |
CN115551982A (zh) * | 2020-05-28 | 2022-12-30 | 联合利华知识产权控股有限公司 | 片剂 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2556561C2 (de) | 1975-12-16 | 1983-04-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von porösen Tabletten |
US4650699A (en) * | 1983-04-18 | 1987-03-17 | Sermetel | Thixotropic alumina coating compositions, parts and methods |
US6066337A (en) | 1994-01-27 | 2000-05-23 | The Board Of Regents Of The University Of Oklahoma And Janssen Pharmaceutica, Inc. | Method for producing a rapidly dissolving dosage form |
US5595761A (en) | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
US5635210A (en) | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
FR2787802B1 (fr) | 1998-12-24 | 2001-02-02 | Pluss Stauffer Ag | Nouvelle charge ou pigment ou mineral traite pour papier, notamment pigment contenant du caco3 naturel, son procede de fabrication, compositions les contenant, et leurs applications |
FR2852600B1 (fr) | 2003-03-18 | 2005-06-10 | Nouveau pigment mineral contenant du carbonate de calcium, suspension aqueuse le contenant et ses usages | |
US20050244493A1 (en) * | 2004-04-30 | 2005-11-03 | Withiam Michael C | Rapidly disintegrating tablets comprising calcium carbonate |
DK2070991T3 (da) | 2007-12-12 | 2010-12-20 | Omya Development Ag | Fremgangsmåde til frembringelse af overflademodificeret, udfældet calciumcarbonat |
JP5490691B2 (ja) * | 2008-06-12 | 2014-05-14 | 株式会社三和化学研究所 | 炭酸カルシウム含有速崩壊性製剤 |
EP2168572A1 (en) * | 2008-09-30 | 2010-03-31 | Omya Development Ag | New controlled release active agent carrier |
EP2198857A1 (en) * | 2008-12-19 | 2010-06-23 | Ratiopharm GmbH | Oral dispersible tablet |
US8303868B2 (en) * | 2009-01-26 | 2012-11-06 | Shin-Etsu Chemical Co., Ltd. | Wet granulation tableting method using aqueous dispersion of low-substituted hydroxypropyl cellulose |
JP4562797B1 (ja) * | 2009-05-29 | 2010-10-13 | マイラン製薬株式会社 | 沈降炭酸カルシウムを有効成分とする口腔内崩壊錠 |
PL2264108T3 (pl) | 2009-06-15 | 2012-07-31 | Omya Int Ag | Sposób wytwarzania przereagowanego powierzchniowo węglanu wapnia, z wykorzystaniem słabego kwasu |
PT2377900E (pt) * | 2010-04-16 | 2013-11-07 | Omya Int Ag | Processo para preparar um material mineral com superfície modificada seus produtos resultantes e suas utilizações |
-
2012
- 2012-10-12 PL PL12188344T patent/PL2719373T3/pl unknown
- 2012-10-12 SI SI201230974A patent/SI2719373T1/sl unknown
- 2012-10-12 DK DK12188344.1T patent/DK2719373T3/en active
- 2012-10-12 EP EP12188344.1A patent/EP2719373B1/en active Active
- 2012-10-12 ES ES12188344.1T patent/ES2628371T3/es active Active
-
2013
- 2013-10-01 TW TW102135466A patent/TWI583387B/zh active
- 2013-10-09 UY UY0001035071A patent/UY35071A/es not_active Application Discontinuation
- 2013-10-09 AR ARP130103663A patent/AR092957A1/es not_active Application Discontinuation
- 2013-10-10 AU AU2013328639A patent/AU2013328639B2/en active Active
- 2013-10-10 PT PT13774204T patent/PT2916816T/pt unknown
- 2013-10-10 US US14/428,052 patent/US20150283082A1/en not_active Abandoned
- 2013-10-10 RU RU2018127317A patent/RU2018127317A/ru unknown
- 2013-10-10 MY MYPI2015701128A patent/MY174635A/en unknown
- 2013-10-10 SG SG11201502290SA patent/SG11201502290SA/en unknown
- 2013-10-10 PL PL13774204T patent/PL2916816T3/pl unknown
- 2013-10-10 MX MX2015004234A patent/MX369779B/es active IP Right Grant
- 2013-10-10 WO PCT/EP2013/071169 patent/WO2014057038A1/en active Application Filing
- 2013-10-10 HU HUE13774204 patent/HUE044281T2/hu unknown
- 2013-10-10 BR BR112015008139-8A patent/BR112015008139B1/pt active IP Right Grant
- 2013-10-10 TR TR2019/09173T patent/TR201909173T4/tr unknown
- 2013-10-10 CN CN201380052937.7A patent/CN104768531A/zh active Pending
- 2013-10-10 ES ES13774204T patent/ES2732841T3/es active Active
- 2013-10-10 EP EP13774204.5A patent/EP2916816B1/en active Active
- 2013-10-10 DK DK13774204.5T patent/DK2916816T3/da active
- 2013-10-10 JP JP2015536128A patent/JP6196676B2/ja active Active
- 2013-10-10 CN CN201910889639.2A patent/CN110742867A/zh active Pending
- 2013-10-10 SI SI201331489T patent/SI2916816T1/sl unknown
- 2013-10-10 CA CA2884912A patent/CA2884912C/en active Active
- 2013-10-10 KR KR1020157010108A patent/KR101740835B1/ko active IP Right Grant
- 2013-10-10 RU RU2015115916A patent/RU2676087C2/ru active
-
2015
- 2015-03-16 IL IL237766A patent/IL237766B/en unknown
- 2015-04-09 CL CL2015000893A patent/CL2015000893A1/es unknown
- 2015-04-14 CO CO15082672A patent/CO7350657A2/es unknown
-
2019
- 2019-06-17 HR HRP20191082TT patent/HRP20191082T1/hr unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |