ES2553091T3 - Nuevos portadores recubiertos de agentes activos de liberación controlada - Google Patents

Nuevos portadores recubiertos de agentes activos de liberación controlada Download PDF

Info

Publication number
ES2553091T3
ES2553091T3 ES12781346.7T ES12781346T ES2553091T3 ES 2553091 T3 ES2553091 T3 ES 2553091T3 ES 12781346 T ES12781346 T ES 12781346T ES 2553091 T3 ES2553091 T3 ES 2553091T3
Authority
ES
Spain
Prior art keywords
controlled release
natural
release agents
calcium carbonate
synthetic calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12781346.7T
Other languages
English (en)
Inventor
Patrick Schwarzentruber
Nicola Di Maiuta
Joachim Schoelkopf
Catherine Jean Ridgway
Patrick A.C. Gane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omya International AG
Original Assignee
Omya International AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47143128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2553091(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP11188597.6A external-priority patent/EP2591772B1/en
Application filed by Omya International AG filed Critical Omya International AG
Application granted granted Critical
Publication of ES2553091T3 publication Critical patent/ES2553091T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Un portador para la liberación controlada de agentes activos, que comprende: - un núcleo, que comprende: - carbonato de calcio natural o sintético que ha reaccionado superficialmente, y - por lo menos un agente activo, en donde dicho por lo menos un agente activo está asociado con dicho carbonato de calcio natural o sintético que ha reaccionado superficialmente, y en donde dicho carbonato de calcio natural o sintético que ha reaccionado superficialmente es un producto de la reacción de carbonato de calcio natural o sintético con dióxido de carbono y uno o más ácidos, en donde el dióxido de carbono es formado in situ mediante el tratamiento con ácido y/o es suministrado desde una fuente externa, y - un recubrimiento que encapsula el núcleo.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8
imagen9
imagen10

Claims (1)

  1. imagen1
    imagen2
    imagen3
ES12781346.7T 2011-11-10 2012-11-08 Nuevos portadores recubiertos de agentes activos de liberación controlada Active ES2553091T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11188597.6A EP2591772B1 (en) 2011-11-10 2011-11-10 New coated controlled release active agent carriers
EP11188597 2011-11-10
US201161559253P 2011-11-14 2011-11-14
US201161559253P 2011-11-14
PCT/EP2012/072161 WO2013068478A1 (en) 2011-11-10 2012-11-08 New coated controlled release active agent carriers

Publications (1)

Publication Number Publication Date
ES2553091T3 true ES2553091T3 (es) 2015-12-04

Family

ID=47143128

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12781346.7T Active ES2553091T3 (es) 2011-11-10 2012-11-08 Nuevos portadores recubiertos de agentes activos de liberación controlada

Country Status (24)

Country Link
US (1) US9579291B2 (es)
EP (1) EP2747752B1 (es)
KR (1) KR101612655B1 (es)
CN (1) CN103957893B (es)
AU (1) AU2012334082B2 (es)
BR (1) BR112014011310B1 (es)
CA (1) CA2851069C (es)
CL (1) CL2014001172A1 (es)
CO (1) CO6940430A2 (es)
DK (1) DK2747752T3 (es)
ES (1) ES2553091T3 (es)
IL (1) IL231959A0 (es)
IN (1) IN2014MN00843A (es)
MX (1) MX346884B (es)
MY (1) MY168425A (es)
PL (1) PL2747752T3 (es)
PT (1) PT2747752E (es)
RU (2) RU2018123688A (es)
SG (1) SG11201401350WA (es)
SI (1) SI2747752T1 (es)
SM (1) SMT201600010B (es)
TW (1) TWI625129B (es)
WO (1) WO2013068478A1 (es)
ZA (1) ZA201403611B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2719376B1 (en) 2012-10-12 2015-03-04 Omya International AG Gastroretentive drug formulation and delivery systems and their method of preparation using functionalized calcium carbonate
WO2014127022A2 (en) * 2013-02-15 2014-08-21 Wellmark International Mineral feed-through formulation
TR201815327T4 (tr) 2015-06-10 2018-11-21 Omya Int Ag Anti-blokaj maddesi olarak yüzeyi tepkimeye girmiş kalsiyum karbonat kullanımı.
EP3176222A1 (en) * 2015-12-01 2017-06-07 Omya International AG Method for the production of granules comprising surface-reacted calcium carbonate
WO2017155906A1 (en) 2016-03-08 2017-09-14 Living Proof, Inc. Long lasting cosmetic compositions
EP3275947A1 (en) * 2016-07-25 2018-01-31 Omya International AG Surface-reacted calcium carbonate with functional cations
EP3400810A1 (en) * 2017-05-11 2018-11-14 Omya International AG Surface-reacted calcium carbonate in food
CN107258776A (zh) * 2017-06-29 2017-10-20 山东大农药业有限公司 一种缓释农药颗粒剂及其制备方法
JP7244494B2 (ja) 2017-09-13 2023-03-22 リビング プルーフ インコーポレイテッド 色保護剤組成物
AU2018333932B2 (en) 2017-09-13 2024-05-02 Living Proof, Inc. Long lasting cosmetic compositions
EP3694491A1 (en) 2017-10-10 2020-08-19 Capsugel Belgium NV Gelling multiparticulates
JP7214730B2 (ja) 2017-11-20 2023-01-30 リビング プルーフ インコーポレイテッド 長期持続性の化粧品性能を達成するための特性
EP3520798A1 (en) * 2018-01-31 2019-08-07 Omya International AG Use of functionalized calcium carbonate as active ingredient
EP3784711A1 (en) 2018-04-27 2021-03-03 Living Proof, Inc. Long lasting cosmetic compositions
EP3598105A1 (en) 2018-07-20 2020-01-22 Omya International AG Method for detecting phosphate and/or sulphate salts on the surface of a substrate or within a substrate, use of a lwir detecting device and a lwir imaging system
KR20200049662A (ko) * 2018-10-31 2020-05-08 (주)아모레퍼시픽 바이오 폴리머를 포함하는 코어-쉘 네트워크 구조체 및 이를 포함하는 조성물
US11896685B2 (en) 2018-10-31 2024-02-13 Amorepacific Corporation Core-shell network structure comprising biopolymer and composition comprising same
US20220105047A1 (en) * 2019-01-16 2022-04-07 Research Cooperation Foundation Of Yeungnam University Microcapsule composition using alginate gel, and method for producing same
KR20210069344A (ko) 2019-12-03 2021-06-11 (주)아모레퍼시픽 바이오 폴리머를 포함하는 효능물질 전달체
CN111436426B (zh) * 2020-05-11 2022-04-08 北京首创股份有限公司 供水管道输水用二次加氯胶囊及其制备方法
AR123009A1 (es) 2020-07-20 2022-10-19 Omya Int Ag Agente estabilizante para composición probiótica

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223896A1 (de) 1972-05-17 1973-11-29 Sanol Arznei Schwarz Gmbh Verfahren zum ueberziehen von feinteiligen arzneimitteln
US4657784A (en) 1986-03-10 1987-04-14 Ecolab Inc. Process for encapsulating particles with at least two coating layers having different melting points
EP0607467B1 (de) * 1992-12-01 1999-06-02 Spirig Ag Pharmazeutische Präparate S(+)-Ibuprofen enthaltende Arzneimittel
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
FR2787802B1 (fr) 1998-12-24 2001-02-02 Pluss Stauffer Ag Nouvelle charge ou pigment ou mineral traite pour papier, notamment pigment contenant du caco3 naturel, son procede de fabrication, compositions les contenant, et leurs applications
FR2852600B1 (fr) 2003-03-18 2005-06-10 Nouveau pigment mineral contenant du carbonate de calcium, suspension aqueuse le contenant et ses usages
FR2871474B1 (fr) 2004-06-11 2006-09-15 Omya Development Ag Nouveau pigment mineral sec contenant du carbonate de calcium, suspension aqueuse le contenant et ses usages
EP1891937A1 (en) 2006-08-25 2008-02-27 Novartis AG Galenic formulations of aliskiren
PT1974807E (pt) 2007-03-21 2010-05-10 Omya Development Ag Processo para a remoção de compostos desreguladores endócrinos
DE602007009124D1 (de) 2007-12-12 2010-10-21 Omya Development Ag Verfahren zur Herstellung von oberflächenreaktives Fällungskalziumkarbonat
EP2168572A1 (en) 2008-09-30 2010-03-31 Omya Development Ag New controlled release active agent carrier
JP5732043B2 (ja) 2009-04-24 2015-06-10 オムヤ インターナショナル アーゲー 活性成分を放出制御するための粒状物質
EP2264108B1 (en) 2009-06-15 2012-02-15 Omya Development AG Process to prepare a surface-reacted calcium carbonate implementing a weak acid
PL2264109T3 (pl) 2009-06-15 2012-07-31 Omya Int Ag Sposób wykorzystania przereagowanego powierzchniowo węglanu wapnia i jego wykorzystanie

Also Published As

Publication number Publication date
IN2014MN00843A (es) 2015-07-03
TW201328709A (zh) 2013-07-16
EP2747752B1 (en) 2015-10-07
KR20140091054A (ko) 2014-07-18
SMT201600010B (it) 2016-02-25
RU2018123688A3 (es) 2022-01-24
SG11201401350WA (en) 2014-05-29
NZ623515A (en) 2016-09-30
US20140248340A1 (en) 2014-09-04
CN103957893B (zh) 2017-08-15
IL231959A0 (en) 2014-05-28
RU2665382C1 (ru) 2018-08-29
CL2014001172A1 (es) 2014-09-12
WO2013068478A1 (en) 2013-05-16
KR101612655B1 (ko) 2016-04-14
CN103957893A (zh) 2014-07-30
EP2747752A1 (en) 2014-07-02
DK2747752T3 (en) 2016-01-18
AU2012334082A1 (en) 2014-04-24
MX346884B (es) 2017-04-05
RU2018123688A (ru) 2019-03-07
ZA201403611B (en) 2015-07-29
PL2747752T3 (pl) 2016-04-29
SI2747752T1 (sl) 2015-12-31
TWI625129B (zh) 2018-06-01
CO6940430A2 (es) 2014-05-09
CA2851069C (en) 2016-05-31
MX2014005466A (es) 2014-08-22
CA2851069A1 (en) 2013-05-16
MY168425A (en) 2018-11-09
US9579291B2 (en) 2017-02-28
BR112014011310A2 (pt) 2017-05-09
AU2012334082B2 (en) 2015-10-29
BR112014011310B1 (pt) 2022-04-12
PT2747752E (pt) 2016-02-08

Similar Documents

Publication Publication Date Title
ES2553091T3 (es) Nuevos portadores recubiertos de agentes activos de liberación controlada
ES2529725T3 (es) Combinaciones de principios activos nematicidas que comprenden fluopiram y Metarhizium
ES2536206T3 (es) Parche medicinal
TN2014000141A1 (en) New coated controlled release active agent carriers
UY35070A (es) ?Sistemas de administración y formulación de fármacos de retención gástrica, y método para su preparación usando carbonato de calcio funcionalizado?.
AR092957A1 (es) Formulacion de forma farmaceutica solida de desintegracion veloz que comprende carbonato de calcio funcionalizado y metodo para su fabricacion
ES2492497T3 (es) Perácidos alfa-ceto y métodos para su producción y uso
AR113360A2 (es) Sistema de generación de aerosol
AR093237A1 (es) Indicacion y activacion de conjuntos de parametros para la codificacion de video
MX2012013752A (es) Producto medico con un recubrimiento libre de particulas que libera una sustancia activa.
UY36313A (es) Composición que comprende un carbonato de calcio reaccionado en la superficie como agente antiaglomerante, y método para producirla
CL2013000163A1 (es) Proceso para la preparacion de material de carbonato de calcio que comprende proveer al menos un material que contenga carbonato de calcio, proveer al menos una sal de un acido graso c5-c28, tratar el material poniendolo en contacto con dicho acido graso y obtener dicho material tratado superficialmente; material de carbonato de calcio; y su uso en el control de material organico en un medio acuoso.
CL2017002136A1 (es) Composición de limpieza abrasiva. (división de solicitud no. 1383-2016)
UY34880A (es) Preparación líquida
MX340238B (es) Particulas fertilizantes recubiertas.
CO6630136A2 (es) Procedimiento para la preparación de 4-{4[({4-cloro-3-(trifluorometil) fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridina-2-carbocamida, sus sales y su monohidrato
AR102207A1 (es) Un método para preparar un filtro de tejido catalizado y un filtro de tejido catalizado
ES2509116T3 (es) Aceptor de color que reacciona formando color con un precursor de colorante, y material de registro termosensible con un aceptor de color de este tipo
AR085732A1 (es) Un dispositivo generador de 1-metilciclopropano
CO2018001368A2 (es) Métodos para administrar enzimas o microbios productores de carbonato de calcio en el fondo del pozo
ES2530731T3 (es) Dispositivos médicos que contienen nitroprusiato y agentes antimicrobianos
PH12016502536A1 (en) Composite preparation comprising 5-a-reductase inhibitor-containing film coating layer, and method for producing the composite preparation
BR112021017878A2 (pt) Carbonato de magnésio com superfície reagida, sistema de liberação, formulação de cuidados domiciliares, métodos para preparar um carbonato de magnésio com superfície reagida e para preparar um sistema de liberação, e, uso de um carbonato de magnésio com superfície reagida e de um sistema de liberação
ES2597030T3 (es) Material compuesto de caucho-cordón de acero
MX354994B (es) Toallita para la aplicación de al menos un principio activo sobre la piel.