AR087451A1 - Derivado de 1,2,3,4-tetrahidroquinolina util para tratamiento de diabetes - Google Patents

Derivado de 1,2,3,4-tetrahidroquinolina util para tratamiento de diabetes

Info

Publication number
AR087451A1
AR087451A1 ARP120102845A ARP120102845A AR087451A1 AR 087451 A1 AR087451 A1 AR 087451A1 AR P120102845 A ARP120102845 A AR P120102845A AR P120102845 A ARP120102845 A AR P120102845A AR 087451 A1 AR087451 A1 AR 087451A1
Authority
AR
Argentina
Prior art keywords
tetrahydroquinoline
diabetes
derived
useful
treatment
Prior art date
Application number
ARP120102845A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR087451(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR087451A1 publication Critical patent/AR087451A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Abstract

La presente proporciona un compuesto de la fórmula (1) o una sal farmacéutica del mismo, un proceso para preparar el compuesto y composición farmacéutica.
ARP120102845A 2011-08-17 2012-08-03 Derivado de 1,2,3,4-tetrahidroquinolina util para tratamiento de diabetes AR087451A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161524462P 2011-08-17 2011-08-17

Publications (1)

Publication Number Publication Date
AR087451A1 true AR087451A1 (es) 2014-03-26

Family

ID=46690732

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120102845A AR087451A1 (es) 2011-08-17 2012-08-03 Derivado de 1,2,3,4-tetrahidroquinolina util para tratamiento de diabetes

Country Status (29)

Country Link
US (1) US8431706B2 (es)
EP (1) EP2744806B1 (es)
JP (1) JP5903162B2 (es)
KR (1) KR101570624B1 (es)
CN (1) CN103687856B (es)
AP (1) AP3589A (es)
AR (1) AR087451A1 (es)
AU (1) AU2012295372A1 (es)
BR (1) BR112014003079A2 (es)
CA (1) CA2843474C (es)
CL (1) CL2014000357A1 (es)
CO (1) CO6880069A2 (es)
CR (1) CR20140052A (es)
DO (1) DOP2014000018A (es)
EA (1) EA022165B1 (es)
EC (1) ECSP14013211A (es)
ES (1) ES2578165T3 (es)
GT (1) GT201400022A (es)
IL (1) IL230635A (es)
IN (1) IN2014MN00191A (es)
MA (1) MA35351B1 (es)
MX (1) MX2014001832A (es)
PE (1) PE20140831A1 (es)
SG (1) SG11201401793PA (es)
TN (1) TN2014000058A1 (es)
TW (1) TWI537262B (es)
UA (1) UA110983C2 (es)
WO (1) WO2013025424A1 (es)
ZA (1) ZA201400705B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2016009176A0 (en) 2013-11-14 2016-04-30 Cadila Healthcare Ltd Novel heterocyclic compounds
US9957219B2 (en) 2013-12-04 2018-05-01 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
CN109666027A (zh) * 2017-10-17 2019-04-23 中国科学院上海药物研究所 一类酰胺结构的gpr40激动剂化合物及其用途
PL3737470T3 (pl) 2018-01-08 2023-05-08 Celon Pharma S.A. Pochodne kwasu 3-fenylo-4-heksynowego jako agoniści gpr40
EP4227302A1 (en) 2018-02-13 2023-08-16 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
JP7242702B2 (ja) 2018-04-19 2023-03-20 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
PT3820572T (pt) 2018-07-13 2023-11-10 Gilead Sciences Inc Inibidores pd-1/pd-l1
US11236085B2 (en) 2018-10-24 2022-02-01 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
AU2020363377A1 (en) 2019-10-07 2022-04-21 Kallyope, Inc. GPR119 agonists
JP2023526625A (ja) 2020-05-19 2023-06-22 キャリーオペ，インク． Ａｍｐｋアクチベーター
CA3183575A1 (en) 2020-06-26 2021-12-30 Iyassu Sebhat Ampk activators
KR20220136800A (ko) * 2021-04-01 2022-10-11 현대약품 주식회사 3-(4-(벤질옥시)페닐)헥스-4-이노익산 유도체의 신규 용도
CN115317484B (zh) * 2022-08-26 2023-07-18 北京箭牧科技有限公司 Ly2922470在制备预防或治疗脑血管疾病或组织缺血再灌注损伤药物中的应用
CN115671105B (zh) * 2022-11-22 2023-10-27 北京箭牧科技有限公司 Ly2922470在制备预防或治疗肾脏疾病药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT199900147A (es) * 1998-09-17 1999-09-06 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
CA2441790A1 (en) * 2001-03-27 2002-10-03 Actelion Pharmaceuticals Ltd. 1,2,3,4-tetrahydroisoquinolines derivatives as urotensin ii receptor antagonists
EA011010B1 (ru) * 2004-02-27 2008-12-30 Эмджен, Инк. Соединения, модулирующие рецептор gpr40, фармацевтическая композиция, способ лечения заболеваний, чувствительных к модулированию рецептора gpr40 (варианты), способ модулирования функции gpr40 (варианты) и способ модулирования циркулирующей концентрации инсулина
JP4875978B2 (ja) * 2004-03-15 2012-02-15 武田薬品工業株式会社 アミノフェニルプロパン酸誘導体
US7517910B2 (en) * 2004-03-30 2009-04-14 Takeda Pharmaceutical Company Limited Alkoxyphenylpropanoic acid derivatives
AR078522A1 (es) * 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis
AR078948A1 (es) * 2009-11-30 2011-12-14 Lilly Co Eli Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes

Also Published As

Publication number Publication date
AP2014007436A0 (en) 2014-02-28
WO2013025424A1 (en) 2013-02-21
TN2014000058A1 (en) 2015-07-01
DOP2014000018A (es) 2014-04-15
AU2012295372A1 (en) 2014-01-23
CN103687856A (zh) 2014-03-26
EA022165B1 (ru) 2015-11-30
GT201400022A (es) 2015-01-16
ZA201400705B (en) 2015-11-25
JP2014521744A (ja) 2014-08-28
EP2744806A1 (en) 2014-06-25
CL2014000357A1 (es) 2014-09-05
CA2843474A1 (en) 2013-02-21
CO6880069A2 (es) 2014-02-28
PE20140831A1 (es) 2014-07-14
EP2744806B1 (en) 2016-04-27
UA110983C2 (uk) 2016-03-10
CN103687856B (zh) 2015-07-22
CA2843474C (en) 2015-12-15
JP5903162B2 (ja) 2016-04-13
SG11201401793PA (en) 2014-09-26
ES2578165T3 (es) 2016-07-21
CR20140052A (es) 2014-06-20
IN2014MN00191A (es) 2015-08-21
EA201490269A1 (ru) 2014-05-30
NZ621248A (en) 2015-08-28
MX2014001832A (es) 2014-02-27
TW201319060A (zh) 2013-05-16
AP3589A (en) 2016-02-15
KR20140041835A (ko) 2014-04-04
IL230635A (en) 2015-11-30
US20130045990A1 (en) 2013-02-21
KR101570624B1 (ko) 2015-11-19
IL230635A0 (en) 2014-03-31
BR112014003079A2 (pt) 2017-02-21
ECSP14013211A (es) 2014-03-31
US8431706B2 (en) 2013-04-30
TWI537262B (zh) 2016-06-11
MA35351B1 (fr) 2014-08-01

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