ECSP14013211A - Nuevo derivado de 1,2,3,4-tetrahidroquinolina útil para el tratamiento de diabetes - Google Patents

Nuevo derivado de 1,2,3,4-tetrahidroquinolina útil para el tratamiento de diabetes

Info

Publication number
ECSP14013211A
ECSP14013211A ECSP14013211A ECSP14013211A EC SP14013211 A ECSP14013211 A EC SP14013211A EC SP14013211 A ECSP14013211 A EC SP14013211A EC SP14013211 A ECSP14013211 A EC SP14013211A
Authority
EC
Ecuador
Prior art keywords
diabetes
tetrahydroquinoline
useful
treatment
new derivative
Prior art date
Application number
Other languages
English (en)
Inventor
Chafiq Hamdouchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP14013211(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP14013211A publication Critical patent/ECSP14013211A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención proporciona un compuesto de la Fórmula siguienteo una sal farmacéutica del mismo, métodos para tratar diabetes usando el compuesto y un proceso para preparar el compuesto.
ECSP14013211 2011-08-17 2014-02-17 Nuevo derivado de 1,2,3,4-tetrahidroquinolina útil para el tratamiento de diabetes ECSP14013211A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161524462P 2011-08-17 2011-08-17

Publications (1)

Publication Number Publication Date
ECSP14013211A true ECSP14013211A (es) 2014-03-31

Family

ID=46690732

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP14013211 ECSP14013211A (es) 2011-08-17 2014-02-17 Nuevo derivado de 1,2,3,4-tetrahidroquinolina útil para el tratamiento de diabetes

Country Status (29)

Country Link
US (1) US8431706B2 (es)
EP (1) EP2744806B1 (es)
JP (1) JP5903162B2 (es)
KR (1) KR101570624B1 (es)
CN (1) CN103687856B (es)
AP (1) AP3589A (es)
AR (1) AR087451A1 (es)
AU (1) AU2012295372A1 (es)
BR (1) BR112014003079A2 (es)
CA (1) CA2843474C (es)
CL (1) CL2014000357A1 (es)
CO (1) CO6880069A2 (es)
CR (1) CR20140052A (es)
DO (1) DOP2014000018A (es)
EA (1) EA022165B1 (es)
EC (1) ECSP14013211A (es)
ES (1) ES2578165T3 (es)
GT (1) GT201400022A (es)
IL (1) IL230635A (es)
IN (1) IN2014MN00191A (es)
MA (1) MA35351B1 (es)
MX (1) MX2014001832A (es)
PE (1) PE20140831A1 (es)
SG (1) SG11201401793PA (es)
TN (1) TN2014000058A1 (es)
TW (1) TWI537262B (es)
UA (1) UA110983C2 (es)
WO (1) WO2013025424A1 (es)
ZA (1) ZA201400705B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201690888A1 (ru) 2013-11-14 2016-10-31 Кадила Хелзкэр Лимитед Новые гетероциклические соединения
EP3076959B1 (en) 2013-12-04 2018-07-04 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
CN109666027A (zh) * 2017-10-17 2019-04-23 中国科学院上海药物研究所 一类酰胺结构的gpr40激动剂化合物及其用途
US11964938B2 (en) 2018-01-08 2024-04-23 Celon Pharma S.A. 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists
CR20200347A (es) 2018-02-13 2020-09-23 Gilead Sciences Inc Inhibidores pd-1/pd-l1
CN112041311B (zh) 2018-04-19 2023-10-03 吉利德科学公司 Pd-1/pd-l1抑制剂
UA126421C2 (uk) 2018-07-13 2022-09-28 Гіліад Сайєнсіз, Інк. Інгібітори pd-1/pd-l1
JP7158577B2 (ja) 2018-10-24 2022-10-21 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
TWI751585B (zh) * 2019-06-28 2022-01-01 美商美國禮來大藥廠 類升糖素肽1受體促效劑
IL291985A (en) 2019-10-07 2022-06-01 Kallyope Inc gpr119 agonists
CA3159650A1 (en) * 2019-10-31 2021-05-06 China Petroleum & Chemical Corporation Supported catalyst, preparation method therefor and application thereof
WO2021236617A1 (en) 2020-05-19 2021-11-25 Kallyope, Inc. Ampk activators
AU2021297323A1 (en) 2020-06-26 2023-02-16 Kallyope, Inc. AMPK activators
CA3213380A1 (en) * 2021-04-01 2022-10-06 Hye Jin Yoo Novel use of 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative
CN115317484B (zh) * 2022-08-26 2023-07-18 北京箭牧科技有限公司 Ly2922470在制备预防或治疗脑血管疾病或组织缺血再灌注损伤药物中的应用
CN115671105B (zh) * 2022-11-22 2023-10-27 北京箭牧科技有限公司 Ly2922470在制备预防或治疗肾脏疾病药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
GT199900147A (es) * 1998-09-17 1999-09-06 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
ES2246399T3 (es) * 2001-03-27 2006-02-16 Actelion Pharmaceuticals Ltd. 1,2,3,4-tetrahidroisoquinolinas como antagonistas derivados del receptor de urotensina ii.
ES2433466T3 (es) * 2004-02-27 2013-12-11 Amgen, Inc Compuestos, composiciones farmacéuticas y métodos para su uso en el tratamiento de trastornos metabólicos
US7786165B2 (en) * 2004-03-15 2010-08-31 Takeda Pharmaceutical Company Limited Aminophenylpropanoic acid derivative
US7517910B2 (en) * 2004-03-30 2009-04-14 Takeda Pharmaceutical Company Limited Alkoxyphenylpropanoic acid derivatives
AR078522A1 (es) * 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis
AR078948A1 (es) * 2009-11-30 2011-12-14 Lilly Co Eli Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes

Also Published As

Publication number Publication date
AP2014007436A0 (en) 2014-02-28
MA35351B1 (fr) 2014-08-01
TW201319060A (zh) 2013-05-16
ES2578165T3 (es) 2016-07-21
AP3589A (en) 2016-02-15
IL230635A (en) 2015-11-30
IL230635A0 (en) 2014-03-31
KR101570624B1 (ko) 2015-11-19
BR112014003079A2 (pt) 2017-02-21
IN2014MN00191A (es) 2015-08-21
GT201400022A (es) 2015-01-16
SG11201401793PA (en) 2014-09-26
ZA201400705B (en) 2015-11-25
WO2013025424A1 (en) 2013-02-21
NZ621248A (en) 2015-08-28
CA2843474C (en) 2015-12-15
TN2014000058A1 (en) 2015-07-01
PE20140831A1 (es) 2014-07-14
US20130045990A1 (en) 2013-02-21
EP2744806A1 (en) 2014-06-25
CL2014000357A1 (es) 2014-09-05
AR087451A1 (es) 2014-03-26
CO6880069A2 (es) 2014-02-28
UA110983C2 (uk) 2016-03-10
CN103687856B (zh) 2015-07-22
EP2744806B1 (en) 2016-04-27
CA2843474A1 (en) 2013-02-21
TWI537262B (zh) 2016-06-11
JP5903162B2 (ja) 2016-04-13
KR20140041835A (ko) 2014-04-04
JP2014521744A (ja) 2014-08-28
CN103687856A (zh) 2014-03-26
AU2012295372A1 (en) 2014-01-23
EA201490269A1 (ru) 2014-05-30
US8431706B2 (en) 2013-04-30
MX2014001832A (es) 2014-02-27
DOP2014000018A (es) 2014-04-15
CR20140052A (es) 2014-06-20
EA022165B1 (ru) 2015-11-30

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