SG11201401793PA - A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes - Google Patents

A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes

Info

Publication number
SG11201401793PA
SG11201401793PA SG11201401793PA SG11201401793PA SG11201401793PA SG 11201401793P A SG11201401793P A SG 11201401793PA SG 11201401793P A SG11201401793P A SG 11201401793PA SG 11201401793P A SG11201401793P A SG 11201401793PA SG 11201401793P A SG11201401793P A SG 11201401793PA
Authority
SG
Singapore
Prior art keywords
diabetes
novel
treatment
derivative useful
tetrahydroquinoline derivative
Prior art date
Application number
SG11201401793PA
Inventor
Chafiq Hamdouchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201401793P(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11201401793PA publication Critical patent/SG11201401793PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201401793PA 2011-08-17 2012-08-09 A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes SG11201401793PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161524462P 2011-08-17 2011-08-17
PCT/US2012/050051 WO2013025424A1 (en) 2011-08-17 2012-08-09 A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes

Publications (1)

Publication Number Publication Date
SG11201401793PA true SG11201401793PA (en) 2014-09-26

Family

ID=46690732

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401793PA SG11201401793PA (en) 2011-08-17 2012-08-09 A Novel 1,2,3,4-Tetrahydroquinoline Derivative Useful for the Treatment of Diabetes

Country Status (29)

Country Link
US (1) US8431706B2 (en)
EP (1) EP2744806B1 (en)
JP (1) JP5903162B2 (en)
KR (1) KR101570624B1 (en)
CN (1) CN103687856B (en)
AP (1) AP3589A (en)
AR (1) AR087451A1 (en)
AU (1) AU2012295372A1 (en)
BR (1) BR112014003079A2 (en)
CA (1) CA2843474C (en)
CL (1) CL2014000357A1 (en)
CO (1) CO6880069A2 (en)
CR (1) CR20140052A (en)
DO (1) DOP2014000018A (en)
EA (1) EA022165B1 (en)
EC (1) ECSP14013211A (en)
ES (1) ES2578165T3 (en)
GT (1) GT201400022A (en)
IL (1) IL230635A (en)
IN (1) IN2014MN00191A (en)
MA (1) MA35351B1 (en)
MX (1) MX2014001832A (en)
PE (1) PE20140831A1 (en)
SG (1) SG11201401793PA (en)
TN (1) TN2014000058A1 (en)
TW (1) TWI537262B (en)
UA (1) UA110983C2 (en)
WO (1) WO2013025424A1 (en)
ZA (1) ZA201400705B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10011609B2 (en) 2013-11-14 2018-07-03 Cadila Healthcare Limited Heterocyclic compounds
US9957219B2 (en) 2013-12-04 2018-05-01 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
CN109666027A (en) * 2017-10-17 2019-04-23 中国科学院上海药物研究所 GPR40 agonist compound of a kind of amide structure and application thereof
US11964938B2 (en) 2018-01-08 2024-04-23 Celon Pharma S.A. 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists
UA126458C2 (en) 2018-02-13 2022-10-05 Гіліад Сайєнсіз, Інк. Pd-1/pd-l1 inhibitors
US10899735B2 (en) 2018-04-19 2021-01-26 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
SI3820572T1 (en) 2018-07-13 2023-12-29 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
WO2020086556A1 (en) 2018-10-24 2020-04-30 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
TWI751585B (en) * 2019-06-28 2022-01-01 美商美國禮來大藥廠 Glucagon-like peptide 1 receptor agonists
EP4041722A4 (en) 2019-10-07 2023-12-13 Kallyope, Inc. Gpr119 agonists
EP4052790A4 (en) * 2019-10-31 2023-12-27 China Petroleum & Chemical Corporation Supported catalyst, preparation method therefor and application thereof
MX2022014505A (en) 2020-05-19 2022-12-13 Kallyope Inc Ampk activators.
CA3183575A1 (en) 2020-06-26 2021-12-30 Iyassu Sebhat Ampk activators
WO2022211303A1 (en) * 2021-04-01 2022-10-06 현대약품 주식회사 Novel use of 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative
CN115317484B (en) * 2022-08-26 2023-07-18 北京箭牧科技有限公司 Application of LY2922470 in preparing medicine for preventing or treating cerebrovascular diseases or tissue ischemia reperfusion injury
CN115671105B (en) * 2022-11-22 2023-10-27 北京箭牧科技有限公司 Application of LY2922470 in preparation of medicines for preventing or treating kidney diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT199900147A (en) * 1998-09-17 1999-09-06 1, 2, 3, 4- TETRAHIDROQUINOLINAS 2-SUBSTITUTED 4-AMINO SUBSTITUTED.
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
BR0207715A (en) * 2001-03-27 2004-03-23 Actelion Pharmaceuticals Ltd Compounds, pharmaceutical compositions, and use of one or more compounds
CA2558585C (en) 2004-02-27 2010-10-12 Amgen Inc. Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
US7786165B2 (en) * 2004-03-15 2010-08-31 Takeda Pharmaceutical Company Limited Aminophenylpropanoic acid derivative
JP4859665B2 (en) * 2004-03-30 2012-01-25 武田薬品工業株式会社 Alkoxyphenylpropanoic acid derivatives
AR078522A1 (en) * 2009-10-15 2011-11-16 Lilly Co Eli SPIROPIPERIDINE COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE TO PREPARE A USEFUL MEDICINAL PRODUCT TO TREAT DIABETES AND INTERMEDIARY COMPOUND FOR SYNTHESIS
AR078948A1 (en) * 2009-11-30 2011-12-14 Lilly Co Eli SPYROPIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION THAT INCLUDE IT AND ITS USE TO PREPARE A USEFUL MEDICINAL PRODUCT TO TREAT DIABETES

Also Published As

Publication number Publication date
EA022165B1 (en) 2015-11-30
ECSP14013211A (en) 2014-03-31
BR112014003079A2 (en) 2017-02-21
ES2578165T3 (en) 2016-07-21
CN103687856A (en) 2014-03-26
WO2013025424A1 (en) 2013-02-21
AU2012295372A1 (en) 2014-01-23
EP2744806B1 (en) 2016-04-27
UA110983C2 (en) 2016-03-10
PE20140831A1 (en) 2014-07-14
GT201400022A (en) 2015-01-16
IL230635A (en) 2015-11-30
JP5903162B2 (en) 2016-04-13
EA201490269A1 (en) 2014-05-30
MA35351B1 (en) 2014-08-01
TN2014000058A1 (en) 2015-07-01
KR20140041835A (en) 2014-04-04
CL2014000357A1 (en) 2014-09-05
CR20140052A (en) 2014-06-20
CA2843474A1 (en) 2013-02-21
NZ621248A (en) 2015-08-28
DOP2014000018A (en) 2014-04-15
ZA201400705B (en) 2015-11-25
AR087451A1 (en) 2014-03-26
AP2014007436A0 (en) 2014-02-28
KR101570624B1 (en) 2015-11-19
IN2014MN00191A (en) 2015-08-21
AP3589A (en) 2016-02-15
TWI537262B (en) 2016-06-11
TW201319060A (en) 2013-05-16
CA2843474C (en) 2015-12-15
CO6880069A2 (en) 2014-02-28
US20130045990A1 (en) 2013-02-21
US8431706B2 (en) 2013-04-30
EP2744806A1 (en) 2014-06-25
MX2014001832A (en) 2014-02-27
CN103687856B (en) 2015-07-22
IL230635A0 (en) 2014-03-31
JP2014521744A (en) 2014-08-28

Similar Documents

Publication Publication Date Title
AP3589A (en) A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes
EP2762476A4 (en) 1,2,4-triazine-6-carboxamide derivative
EP2699091A4 (en) 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
HK1198586A1 (en) 6-difluoromethyl-5,6-dihydro-2h-[1,4]oxazin-3-amine derivatives 6--56--2h-[14]-3-
HK1192757A1 (en) Substituted 4-aryl-n-phenyl-1,3,5-triazin-2-amines 4--n--135--2-
HK1206938A1 (en) Process for the preparation of 3-chloro-4,5,6-trifluoro- picolinonitrile 3--456--
HK1199242A1 (en) Process for the production of 1,3-butadiene 13-
EP2687519A4 (en) 1,2-benzisothiazol-3-one compound production method
EP2883870B8 (en) Method for producing 1,4-benzoxazine compound
HK1190706A1 (en) Sec-hydroxycyclohexyl derivatives as hsl inhibitors for the treatment diabetes hsl -
PL2771328T3 (en) Process for preparing 1,2-benzisothiazolin-3-one
PL2734492T3 (en) Process for the preparation of 1, 1, 1 - trifluoropropane
IL228757A0 (en) Process for the preparation of a sulfated derivative of 3,5-diiodo-o-{3-iodphenyl}-l-tyrosine
PL392489A1 (en) Process for the preparation of 3�, 7?-dihydroxy-5?-androst-17-one
PL390553A1 (en) Process for the preparation of 1,2-epoxybutan-3-ol
PL390554A1 (en) Process for the preparation of 2,3-epoxybutan-1-ol
GB201102024D0 (en) Novel heterocyclic compounds 3
GB201101822D0 (en) Novel heterocyclic compounds 2
GB201101821D0 (en) Novel heterocyclic compounds 1
GB201101823D0 (en) Novel heterocyclic compounds 4
IL222349A0 (en) A process for the preparation of isoserine derivatives
IL222929A0 (en) Process for preparing substituted 1, 3 - dihydro - 2h - indol - 2 - ones
AU2012900131A0 (en) "Heterocyclic compounds"
GB201113450D0 (en) Novel compounds 60
GB201113448D0 (en) Novel compounds 61