AR079551A1 - Anticuerpos anti-her3 y usos de los mismos - Google Patents

Anticuerpos anti-her3 y usos de los mismos

Info

Publication number
AR079551A1
AR079551A1 ARP100104773A ARP100104773A AR079551A1 AR 079551 A1 AR079551 A1 AR 079551A1 AR P100104773 A ARP100104773 A AR P100104773A AR P100104773 A ARP100104773 A AR P100104773A AR 079551 A1 AR079551 A1 AR 079551A1
Authority
AR
Argentina
Prior art keywords
same
her3 antibodies
antibodies
her3
nucleic acid
Prior art date
Application number
ARP100104773A
Other languages
English (en)
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42126432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR079551(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of AR079551A1 publication Critical patent/AR079551A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Anticuerpos ligantes de HER3 humano (anticuerpo anti-HER3) a método para su produccion, a composiciones farmacéuticas que contienen dichos anticuerpos, y a usos de los mismos. Acido nucleico, vector de expresion, célula huésped, método de tratamiento de cáncer.
ARP100104773A 2009-12-22 2010-12-20 Anticuerpos anti-her3 y usos de los mismos AR079551A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09015831 2009-12-22

Publications (1)

Publication Number Publication Date
AR079551A1 true AR079551A1 (es) 2012-02-01

Family

ID=42126432

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100104773A AR079551A1 (es) 2009-12-22 2010-12-20 Anticuerpos anti-her3 y usos de los mismos

Country Status (33)

Country Link
US (4) US8859737B2 (es)
EP (1) EP2516469B1 (es)
JP (2) JP5680671B2 (es)
KR (2) KR20120098911A (es)
CN (1) CN102822201B (es)
AR (1) AR079551A1 (es)
AU (1) AU2010335282B2 (es)
BR (1) BR112012015255A2 (es)
CA (1) CA2782571C (es)
CL (1) CL2012001649A1 (es)
CO (1) CO6551674A2 (es)
CR (1) CR20120284A (es)
CY (1) CY1117563T1 (es)
DK (1) DK2516469T3 (es)
EC (1) ECSP12011995A (es)
ES (1) ES2571226T3 (es)
HK (1) HK1175183A1 (es)
HR (1) HRP20160737T1 (es)
HU (1) HUE029026T2 (es)
IL (1) IL220162A (es)
MA (1) MA33892B1 (es)
MX (1) MX2012007340A (es)
MY (1) MY161909A (es)
NZ (1) NZ600262A (es)
PE (1) PE20121616A1 (es)
PL (1) PL2516469T3 (es)
RS (1) RS54795B1 (es)
RU (1) RU2560583C2 (es)
SG (1) SG181894A1 (es)
SI (1) SI2516469T1 (es)
TW (1) TWI421092B (es)
UA (1) UA107821C2 (es)
WO (1) WO2011076683A1 (es)

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US9273143B2 (en) 2011-09-30 2016-03-01 Regeneron Pharmaceuticals, Inc. Methods and compositions comprising a combination of an anti-ErbB3 antibody and an anti-EGFR antibody
ES2694153T3 (es) * 2011-09-30 2018-12-18 Regeneron Pharmaceuticals, Inc. Anticuerpos anti-ErbB3 y usos de los mismos
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Also Published As

Publication number Publication date
US10196456B2 (en) 2019-02-05
CA2782571C (en) 2018-01-23
US9611331B2 (en) 2017-04-04
IL220162A0 (en) 2012-07-31
PE20121616A1 (es) 2012-12-05
HRP20160737T1 (hr) 2016-07-15
WO2011076683A1 (en) 2011-06-30
RU2560583C2 (ru) 2015-08-20
JP5680671B2 (ja) 2015-03-04
SG181894A1 (en) 2012-08-30
CA2782571A1 (en) 2011-06-30
US20140377273A1 (en) 2014-12-25
NZ600262A (en) 2013-06-28
CR20120284A (es) 2012-09-04
US20140377272A1 (en) 2014-12-25
KR20140130751A (ko) 2014-11-11
JP2015109848A (ja) 2015-06-18
US20110171222A1 (en) 2011-07-14
TWI421092B (zh) 2014-01-01
HUE029026T2 (en) 2017-01-30
KR20120098911A (ko) 2012-09-05
CN102822201B (zh) 2014-09-24
CO6551674A2 (es) 2012-10-31
CY1117563T1 (el) 2017-04-26
MY161909A (en) 2017-05-15
DK2516469T3 (en) 2016-05-02
CN102822201A (zh) 2012-12-12
ES2571226T3 (es) 2016-05-24
BR112012015255A2 (pt) 2017-01-10
JP2013514793A (ja) 2013-05-02
IL220162A (en) 2017-04-30
PL2516469T3 (pl) 2017-08-31
MA33892B1 (fr) 2013-01-02
AU2010335282A1 (en) 2012-07-12
EP2516469A1 (en) 2012-10-31
AU2010335282B2 (en) 2015-05-21
MX2012007340A (es) 2012-08-01
CL2012001649A1 (es) 2012-10-12
ECSP12011995A (es) 2012-07-31
US8859737B2 (en) 2014-10-14
RS54795B1 (sr) 2016-10-31
UA107821C2 (en) 2015-02-25
EP2516469B1 (en) 2016-03-30
HK1175183A1 (en) 2013-06-28
TW201130510A (en) 2011-09-16
US20170174784A1 (en) 2017-06-22
RU2012129735A (ru) 2014-01-27
SI2516469T1 (sl) 2016-05-31

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