AR079536A1 - Granulos para preparaciones farmaceuticas, metodo y aparato para su produccion - Google Patents
Granulos para preparaciones farmaceuticas, metodo y aparato para su produccionInfo
- Publication number
- AR079536A1 AR079536A1 ARP100104755A ARP100104755A AR079536A1 AR 079536 A1 AR079536 A1 AR 079536A1 AR P100104755 A ARP100104755 A AR P100104755A AR P100104755 A ARP100104755 A AR P100104755A AR 079536 A1 AR079536 A1 AR 079536A1
- Authority
- AR
- Argentina
- Prior art keywords
- granules
- pharmaceutical
- pharmaceutical preparation
- active ingredient
- ingredient
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 5
- 239000008187 granular material Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical group NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 abstract 1
- 229960004963 mesalazine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Reivindicacion 1: Una preparacion farmacéutica que comprende gránulos de los cuales cada uno tiene un ingrediente activo farmacéutico y de los cuales cada uno tiene un eje predeterminado y el mismo perfil transversal predeterminado, en donde por lo menos 80% en cantidad de estos gránulos tienen una proporcion de aspecto menor de 2.2. Reivindicacion 8: La preparacion farmacéutica de cualquier reivindicacion precedente, en donde el ingrediente activo farmacéutico comprende un ingrediente anti-inflamatorio. Reivindicacion 9: La preparacion farmacéutica de cualquier reivindicacion precedente, en donde el ingrediente activo farmacéutico es 5-ácido aminosalicílico. Reivindicacion 20: El uso de un separador de longitud en un método para producir una preparacion farmacéutica, en donde el uso ocurre durante la seleccion de gránulos de los cuales cada uno tiene un eje predeterminado y el mismo perfil transversal predeterminado y del cual por lo menos una cantidad tiene un ingrediente activo farmacéutico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179877A EP2340812A1 (en) | 2009-12-18 | 2009-12-18 | Granules for pharmaceutical preparations, methods and apparatus for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR079536A1 true AR079536A1 (es) | 2012-02-01 |
Family
ID=42110308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104755A AR079536A1 (es) | 2009-12-18 | 2010-12-20 | Granulos para preparaciones farmaceuticas, metodo y aparato para su produccion |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US8765185B2 (es) |
| EP (2) | EP2340812A1 (es) |
| JP (1) | JP5593396B2 (es) |
| KR (1) | KR101882880B1 (es) |
| CN (2) | CN105769772A (es) |
| AR (1) | AR079536A1 (es) |
| AU (1) | AU2010332884B2 (es) |
| BR (1) | BR112012014935B1 (es) |
| CA (1) | CA2784235C (es) |
| DK (1) | DK2512453T3 (es) |
| ES (1) | ES2612870T3 (es) |
| HR (1) | HRP20161639T1 (es) |
| HU (1) | HUE031228T2 (es) |
| IL (1) | IL220319A (es) |
| JO (1) | JO3762B1 (es) |
| LT (1) | LT2512453T (es) |
| MX (2) | MX2012006851A (es) |
| NL (1) | NL1038373C2 (es) |
| NZ (1) | NZ600582A (es) |
| PL (1) | PL2512453T3 (es) |
| PT (1) | PT2512453T (es) |
| RS (1) | RS55438B1 (es) |
| RU (1) | RU2584349C2 (es) |
| SI (1) | SI2512453T1 (es) |
| TW (1) | TWI511723B (es) |
| WO (1) | WO2011073245A2 (es) |
| ZA (1) | ZA201204441B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004093883A2 (en) * | 2003-04-23 | 2004-11-04 | Ferring B.V. | Sachet for a pharmaceutical composition |
| EP2350096B1 (en) | 2008-10-02 | 2019-12-11 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| EP2340812A1 (en) | 2009-12-18 | 2011-07-06 | Ferring International Center S.A. | Granules for pharmaceutical preparations, methods and apparatus for their production |
| US20140141075A1 (en) | 2012-11-21 | 2014-05-22 | Warner Chilcott Company, Llc | 5-aminosalicylic acid capsule formulation |
| DE202017102645U1 (de) * | 2017-05-03 | 2018-08-06 | Romaco Kilian Gmbh | Ablaufvorrichtung für Presslinge einer Rundläufer-Tablettenpresse sowie Rundläufer-Tablettenpresse mit Ablaufvorrichtung |
| RU2667637C1 (ru) * | 2017-06-26 | 2018-09-21 | Гермес Арцнаймиттель ГмбХ | Фармацевтическая композиция для перорального применения, содержащая n-ацетилцистеин с маскированным вкусом |
| EP3459527B1 (en) | 2017-09-20 | 2022-11-23 | Tillotts Pharma Ag | Method for preparing a solid dosage form comprising antibodies by wet granulation, extrusion and spheronization |
| EP3459529A1 (en) | 2017-09-20 | 2019-03-27 | Tillotts Pharma Ag | Preparation of sustained release solid dosage forms comprising antibodies by spray drying |
| EP3459528B1 (en) | 2017-09-20 | 2022-11-23 | Tillotts Pharma Ag | Preparation of solid dosage forms comprising antibodies by solution/suspension layering |
| KR102161235B1 (ko) * | 2020-07-22 | 2020-09-29 | 주식회사 피티케이 | 이송 일체형 과립 제조 장치 및 방법 |
| CN114472139A (zh) * | 2022-01-04 | 2022-05-13 | 安徽宏信药业发展有限公司 | 一种中药药丸干燥筛选装置 |
| CN115445902B (zh) * | 2022-09-21 | 2023-06-06 | 重庆科技学院 | 一种条形颗粒物三维尺寸分选方法及装置 |
| CN116942532B (zh) * | 2023-09-20 | 2023-12-12 | 北京爱力佳医药科技有限公司 | 一种粉状药物制备装置 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1981002671A1 (en) | 1980-03-20 | 1981-10-01 | Ferring Farma Lab | Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease by oral administration |
| US4720473A (en) * | 1986-03-10 | 1988-01-19 | Cri International, Inc. | Production of improved catalyst-type particles using length and density grading |
| CA1294943C (en) * | 1986-03-10 | 1992-01-28 | J. Gary Welch | Production of improved catalyst-type particles using length and density grading |
| JPH0827133B2 (ja) * | 1993-07-13 | 1996-03-21 | 不二パウダル株式会社 | 湿潤粉粒体の処理装置 |
| ES2149733T5 (es) | 1995-12-21 | 2008-05-01 | Farmaceutisk Laboratorium Ferring A/S | Composicion farmaceutica oral de liberacion modificada que contiene 5-asa y metodo para el tratamiento de enfermedades intestinales. |
| US6004581A (en) * | 1995-12-21 | 1999-12-21 | Farmaceutisk Laboratorium Ferring A/S | Modified release oral pharmaceutical composition and method for the treatment of bowel diseases |
| AUPO637197A0 (en) | 1997-04-23 | 1997-05-15 | F.H. Faulding & Co. Limited | Taste-masked pharmaceutical compositions |
| DE19724181A1 (de) * | 1997-06-09 | 1998-12-10 | Bayer Ag | Multiple-unit-retard-Zubereitungen und Verfahren zu ihrer Herstellung |
| JP2000128774A (ja) | 1998-10-26 | 2000-05-09 | Tanabe Seiyaku Co Ltd | 薬物を含有する球形微粒子の製法 |
| US6146685A (en) | 1998-11-05 | 2000-11-14 | Delsys Pharmaceutical Corporation | Method of deposition a dry powder and dispensing device |
| PT1146862E (pt) * | 1999-01-29 | 2003-09-30 | Disphar Int Bv | Composicoes farmaceuticas |
| US6735487B1 (en) | 1999-07-01 | 2004-05-11 | Ods Properties, Inc. | Interactive wagering system with promotions |
| GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
| US8282955B2 (en) | 2001-10-15 | 2012-10-09 | Ferring B.V. | Method for the preparation of a pharmaceutical composition comprising 5-aminosalicylic acid for use in treatment of ulcerative colitis and Crohn's disease |
| PT1441700E (pt) * | 2001-10-15 | 2007-10-29 | Ferring Bv | Método para a preparação de uma composição compreendendo ácido 5-aminosalicílico para uso em tratamento de colites ulcerosas ou da doença de crohn |
| US7445796B2 (en) | 2002-08-19 | 2008-11-04 | L. Perrigo Company | Pharmaceutically active particles of a monomodal particle size distribution and method |
| WO2004093883A2 (en) | 2003-04-23 | 2004-11-04 | Ferring B.V. | Sachet for a pharmaceutical composition |
| EP1470819A1 (en) * | 2003-04-23 | 2004-10-27 | Ferring B.V. | High drug load mesalazine sachet |
| EP1547601A1 (en) | 2003-12-23 | 2005-06-29 | Ferring B.V. | Coating method |
| US7207505B2 (en) | 2004-06-04 | 2007-04-24 | Bender Martin P | Method for producing small granules |
| DE102004028977A1 (de) * | 2004-06-16 | 2006-01-05 | Add Advanced Drug Delivery Technologies Ltd. | Neutralpellets |
| WO2007061717A2 (en) | 2005-11-17 | 2007-05-31 | Teva Pharmaceutical Industries, Ltd. | Methods for isolating propargylated aminoindans |
| EP2340812A1 (en) | 2009-12-18 | 2011-07-06 | Ferring International Center S.A. | Granules for pharmaceutical preparations, methods and apparatus for their production |
-
2009
- 2009-12-18 EP EP09179877A patent/EP2340812A1/en not_active Withdrawn
-
2010
- 2010-11-10 NL NL1038373A patent/NL1038373C2/en not_active IP Right Cessation
- 2010-12-15 PL PL10793226T patent/PL2512453T3/pl unknown
- 2010-12-15 LT LTEP10793226.1T patent/LT2512453T/lt unknown
- 2010-12-15 KR KR1020127018413A patent/KR101882880B1/ko active IP Right Grant
- 2010-12-15 MX MX2012006851A patent/MX2012006851A/es active IP Right Grant
- 2010-12-15 JP JP2012543713A patent/JP5593396B2/ja active Active
- 2010-12-15 EP EP10793226.1A patent/EP2512453B1/en active Active
- 2010-12-15 NZ NZ600582A patent/NZ600582A/en unknown
- 2010-12-15 BR BR112012014935-0A patent/BR112012014935B1/pt active IP Right Grant
- 2010-12-15 AU AU2010332884A patent/AU2010332884B2/en active Active
- 2010-12-15 WO PCT/EP2010/069733 patent/WO2011073245A2/en active Application Filing
- 2010-12-15 SI SI201031345A patent/SI2512453T1/sl unknown
- 2010-12-15 JO JOP/2010/0446A patent/JO3762B1/ar active
- 2010-12-15 CN CN201610133023.9A patent/CN105769772A/zh active Pending
- 2010-12-15 MX MX2014011350A patent/MX351365B/es unknown
- 2010-12-15 RS RS20161111A patent/RS55438B1/sr unknown
- 2010-12-15 DK DK10793226.1T patent/DK2512453T3/en active
- 2010-12-15 RU RU2012124834/15A patent/RU2584349C2/ru active
- 2010-12-15 US US13/516,145 patent/US8765185B2/en active Active
- 2010-12-15 PT PT107932261T patent/PT2512453T/pt unknown
- 2010-12-15 HU HUE10793226A patent/HUE031228T2/en unknown
- 2010-12-15 ES ES10793226.1T patent/ES2612870T3/es active Active
- 2010-12-15 CN CN201080063456.2A patent/CN102791257B/zh active Active
- 2010-12-15 CA CA2784235A patent/CA2784235C/en active Active
- 2010-12-17 TW TW099144475A patent/TWI511723B/zh active
- 2010-12-20 AR ARP100104755A patent/AR079536A1/es not_active Application Discontinuation
-
2012
- 2012-06-12 IL IL220319A patent/IL220319A/en active IP Right Grant
- 2012-06-15 ZA ZA2012/04441A patent/ZA201204441B/en unknown
-
2014
- 2014-05-16 US US14/279,806 patent/US9114083B2/en active Active
-
2016
- 2016-12-05 HR HRP20161639TT patent/HRP20161639T1/hr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |